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  • Open Access

    ARTICLE

    The Correlation Between Texture Features and Fibrous Cap Thickness of Lipid-Rich Atheroma Based on Optical Coherence Tomography Imaging

    Chunliu He1, Jiaqiu Wang2, Yuxiang Huang1, Tongjing Zhu1, Yuehong Miao1, Zhiyong Li1,2*

    Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 23-36, 2016, DOI:10.3970/mcb.2016.013.027

    Abstract Fibrous cap thickness (FCT) is seen as critical to plaque vulnerability. Therefore, the development of automatic algorithms for the quantification of FCT is for estimating cardiovascular risk of patients. Intravascular optical coherence tomography (IVOCT) is currently the only in vivo imaging modality with which FCT, the critical component of plaque vulnerability, can be assessed accurately. This study was aimed to discussion the correlation between the texture features of OCT images and the FCT in lipid-rich atheroma. Methods: Firstly, a full automatic segmentation algorithm based on unsupervised fuzzy c means (FCM) clustering with geometric constrains was developed to segment the ROIs… More >

  • Open Access

    ARTICLE

    Additive Manufacturing of Anatomical Models from Computed Tomography Scan Data

    Y. Gür*

    Molecular & Cellular Biomechanics, Vol.11, No.4, pp. 249-258, 2014, DOI:10.3970/mcb.2014.011.249

    Abstract The purpose of the study presented here was to investigate the manufacturability of human anatomical models from Computed Tomography (CT) scan data via a 3D desktop printer which uses fused deposition modelling (FDM) technology. First, Digital Imaging and Communications in Medicine (DICOM) CT scan data were converted to 3D Standard Triangle Language (STL) format by using InVaselius digital imaging program. Once this STL file is obtained, a 3D physical version of the anatomical model can be fabricated by a desktop 3D FDM printer. As a case study, a patient’s skull CT scan data was considered, and a tangible version of… More >

  • Open Access

    ARTICLE

    Novel Approach for Automatic Region of Interest and Seed Point Detection in CT Images Based on Temporal and Spatial Data

    Zhe Liu1, Charlie Maere1,*, Yuqing Song1

    CMC-Computers, Materials & Continua, Vol.59, No.2, pp. 669-686, 2019, DOI:10.32604/cmc.2019.04590

    Abstract Accurately finding the region of interest is a very vital step for segmenting organs in medical image processing. We propose a novel approach of automatically identifying region of interest in Computed Tomography Image (CT) images based on temporal and spatial data . Our method is a 3 stages approach, 1) We extract organ features from the CT images by adopting the Hounsfield filter. 2)We use these filtered features and introduce our novel approach of selecting observable feature candidates by calculating contours’ area and automatically detect a seed point. 3) We use a novel approach to track the growing region changes… More >

  • Open Access

    ARTICLE

    A New Inverse Algorithm for Tomographic Reconstruction of Damage Images Using Lamb Waves

    M. Morii1, N. Hu1,2, H. Fukunaga3, J.H. Li1, Y.L. Liu1, S. Atobe3, Alamusi3, J.H. Qiu4

    CMC-Computers, Materials & Continua, Vol.26, No.1, pp. 37-66, 2011, DOI:10.3970/cmc.2011.026.037

    Abstract Lamb wave tomography (LWT) is a potential and efficient technique for non-destructive tomographic reconstruction of damage images in structural components or materials. A new two-stage inverse algorithm with a small amount of scanning data for quickly reconstructing damage images in aluminum and CFRP laminated plates was proposed in this paper. Due to its high sensitivity to damages, the amplitude decrease of transmitted Lamb waves after travelling through the inspected region was employed as a key signal parameter related to the attenuation of Lamb waves in propagation routes. A through-thickness circular hole and a through-thickness elliptical hole in two aluminum plates,… More >

  • Open Access

    ARTICLE

    Automatic Delineation of Lung Parenchyma Based on Multilevel Thresholding and Gaussian Mixture Modelling

    S. Gopalakrishnan1, *, A. Kandaswamy2

    CMES-Computer Modeling in Engineering & Sciences, Vol.114, No.2, pp. 141-152, 2018, DOI:10.3970/cmes.2018.114.141

    Abstract Delineation of the lung parenchyma in the thoracic Computed Tomography (CT) is an important processing step for most of the pulmonary image analysis such as lung volume extraction, lung nodule detection and pulmonary vessel segmentation. An automatic method for accurate delineation of lung parenchyma in thoracic Computed Tomography images is presented in this paper. The proposed method involves a segmentation phase followed by a lung boundary correction technique. The tissues in the thoracic Computed Tomography can be represented by a number of Gaussians. We propose a histogram utilized Adaptive Multilevel Thresholding (AMT) for estimating the total number of Gaussians and… More >

  • Open Access

    ARTICLE

    An approximately H1-optimal Petrov-Galerkin meshfree method: application to computation of scattered light for optical tomography

    N Pimprikar1, J Teresa2, D Roy1,3, R M Vasu4, K Rajan4

    CMES-Computer Modeling in Engineering & Sciences, Vol.92, No.1, pp. 33-61, 2013, DOI:10.3970/cmes.2013.092.033

    Abstract Nearly pollution-free solutions of the Helmholtz equation for k-values corresponding to visible light are demonstrated and verified through experimentally measured forward scattered intensity from an optical fiber. Numerically accurate solutions are, in particular, obtained through a novel reformulation of the H1 optimal Petrov-Galerkin weak form of the Helmholtz equation. Specifically, within a globally smooth polynomial reproducing framework, the compact and smooth test functions are so designed that their normal derivatives are zero everywhere on the local boundaries of their compact supports. This circumvents the need for a priori knowledge of the true solution on the support boundary and relieves the… More >

  • Open Access

    ARTICLE

    Numerical Simulation of Graphite Properties Using X-ray Tomography and Fast Multipole Boundary Element Method

    H. T. Wang, G. Hall, S. Y. Yu, Z. H. Yao

    CMES-Computer Modeling in Engineering & Sciences, Vol.37, No.2, pp. 153-174, 2008, DOI:10.3970/cmes.2008.037.153

    Abstract Graphite materials are widely used in gas-cooled nuclear reactors as both moderators and reflectors. The graphite properties change when the microstructure damage occurs due to the in-core radiation and oxidation, thereby having a strong impact on the service life of graphite. In this paper, the X-ray tomography and the boundary element method (BEM) are introduced to the microstructure modeling and numerical simulations of both the mechanical and thermal property changes of nuclear graphite due to radiolytic oxidation. The model is established by the three-dimensional X-ray scan on the isotropic nuclear graphite Gilsocarbon, which is used in the UK commercial reactors.… More >

  • Open Access

    ARTICLE

    The Detection of Super-elliptical Inclusions in Infrared Computerised Axial Tomography

    N.S.Mera1, L. Elliott2, D.B.Ingham2

    CMES-Computer Modeling in Engineering & Sciences, Vol.15, No.2, pp. 107-114, 2006, DOI:10.3970/cmes.2006.015.107

    Abstract The purpose of this study is to investigate the efficiency, accuracy and rate of convergence of an evolutionary algorithm for detecting inclusions parametrised by superellipses in non-destructive evaluation and testing. The inverse problem investigated consists of identifying the geometry of discontinuities in a conductive material from Cauchy data measurements taken on the boundary. Temperature and heat flux are measured on the outside boundary of the domain and the position and the size of a super-elliptical inclusion are determined by minimising an objective functional using an evolution strategy. The super-elliptical form allows the parametric model to characterise a variety of shapes… More >

  • Open Access

    ARTICLE

    Methodology for Numerical Simulation of Trabecular Bone Structures Mechanical Behavior

    M.A. Argenta1, A.P. Gebert2, E.S. Filho3, B.A. Felizari4, M.B. Hecke5

    CMES-Computer Modeling in Engineering & Sciences, Vol.79, No.3&4, pp. 159-182, 2011, DOI:10.3970/cmes.2011.079.159

    Abstract Various methods in the literature proposesequations to calculate the stiffness as a function of density of bone tissue such as apparent density and ash density among others[Helgason, Perilli, Schileo, Taddei, Brynjolfsson and Viceconti, 2008]. Other ones present a value of an equivalent elasticity modulus, obtained by statistical adjustments of curves generated through mechanical compression tests over various specimens[Chevalier, Pahr, Allmer, Charlebois and Zysset, 2007; Cuppone, Seedhom, Berry and Ostell, 2004]. Bone tissue is a material withdifferent behaviors according to the scale of observation. It has a complex composite hierarchical structure, which is responsible for assign optimal mechanical properties. Its characteristics,… More >

  • Open Access

    ARTICLE

    A Thermal Tomography Problem in Estimating the Unknown Interfacial Enclosure in a Multiple Region Domain with an Internal Cavity

    Cheng-Hung Huang1, Meng-Ting Chaing1

    CMES-Computer Modeling in Engineering & Sciences, Vol.53, No.2, pp. 153-180, 2009, DOI:10.3970/cmes.2009.053.153

    Abstract A three-dimensional thermal tomography problem (or inverse geometry problem) in estimating the unknown irregular shape of interfacial enclosure (or surface) for a multiple region domain with an internal cavity by using the steepest descent method (SDM) and a general purpose commercial code CFD-ACE+ is examined in the present work based on the simulated measured temperature distributions on the outer surface obtained by infrared thermography. The advantage of calling CFD-ACE+ as a subroutine in this thermal tomography problem lies in its characteristics of easily-handling the moving boundary problem considered here since it has the function of automatic grid generation. Three test… More >

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