Xiaohang He¹, Minjie Liu², Zhengwu Fang¹, Dongfang Ma^1,2,3,*, Yilin Zhou^1,3,*, Junliang Yin¹

Phyton-International Journal of Experimental Botany, Vol.90, No.3, pp. 971-986, 2021, DOI:10.32604/phyton.2021.012726

Abstract Plant AT-rich sequence and zinc-binding protein (PLATZ) is a plant transcription factor that has been studied in corn. PLATZ can non-specifically bind to sequences rich in A/T bases to induce transcriptional repression. It is involved in the regulation of dehydration tolerance in seeds. In this study, we performed bioinformatics analysis to identify and characterize wheat PLATZ(TaPLATZ)genes. We identified 49 wheat PLATZ genes by searching the wheat genome by using known PLATZ gene sequences from rice, Arabidopsis, and maize. Phylogenetic analysis on PLATZ gene sequences from different species was performed. We found that PLATZs could be divided into three groups. The… More >

FANGLIAN HE¹, WEIQING DONG^1,*, SHAOLONG WEI^2,*, ZUYANG QIU³, JINGLI HUANG⁴, HUIPING JIANG¹, SHIYU HUANG¹, LILI LIU³

BIOCELL, Vol.45, No.3, pp. 785-796, 2021, DOI:10.32604/biocell.2021.014418

Abstract Taro (Colocasia esculenta (L.) Schott) is an important crop in Africa, Southeast Asia, and subtropics and is used as a food and medicine. The purple color pigmentation is an appealing character in taro. We sampled taro corms of the cultivar ‘Lipu Taro’ at four developmental stages, including LPYS1 (without purple pigment, 50 days of development (DOD)), LPYS2 (very few purple pigments, 75 DOD), LPYS3 (moderate purple pigments, 115 DOD) and LPYS4 (high purple pigments, 205 DOD). The purpose of our study was to identify the key genes underpinning the purple pigmentation in taro based on RNA-sequencing. Through RNA-Seq, 6453 differentially… More >

Víctor A. Sánchez-Camargo^1,2, Samantha Romero-Rodríguez¹, Jorge M. Vázquez-Ramos^1,*

Phyton-International Journal of Experimental Botany, Vol.90, No.2, pp. 307-330, 2021, DOI:10.32604/phyton.2021.014967

Abstract The E2F/DP pathway is a widely conserved regulatory mechanism in pluricellular organisms. The family of E2F and DP transcription factors was originally described having a role in the transition from the G1 to the S phase of the cell cycle. However, the discovery of hundreds of possible gene targets and their involvement in many other biochemical processes, soon showed that they participated in cell development and differentiation, chromatin remodeling, DNA repair and others. The E2F/DP transcription factors can act as either activators or repressors of transcription depending on their association to other regulatory proteins, particularly the retinoblastoma protein, or even… More >

Haoliang Zhang^1,*, Xiaowei Xing², Yang Liu¹, Shuangli Li¹, Weiyuan Li³

Oncologie, Vol.22, No.2, pp. 107-116, 2020, DOI:10.32604/oncologie.2020.012494

Abstract Lung cancer is the leading cause of death in cancer patients. Based on a modular and comprehensive analysis method, it is intended to identify their common pathogenesis. We downloaded data and analyzed differences in lung adenocarcinoma samples, lung squamous cell carcinoma samples, and normal samples. Co-expression analysis, enrichment analysis, and hypergeometric testing were used to predict transcription factors, ncRNAs, and retrospective target genes. We get 4596 differentially expressed genes in common differences in high multiples and clustered into 14 modules dysfunction. The 14 genes (including DOK2, COL5A1, and TSPAN8) have the highest connectivity in the dysfunction module and are identified… More >

Tamilselvan SUBRAMANI^1,2, Suresh RAO², Kamatchiammal SENTHILKUMAR³, Soundararajan PERIASAMY⁴, Noorjahan Banu ALITHEEN¹

BIOCELL, Vol.37, No.3, pp. 71-76, 2013, DOI:10.32604/biocell.2013.37.071

Abstract The present study demonstrates that the expression of c-Jun and c-Fos are elevated in gingival fibroblast cells treated with angiotensin II and cyclosporine. The healthy human gingival tissues were collected and gingival fibroblasts were isolated and cultured. We used RT-PCR and Western blot analysis to identify the expression of c-Jun and c-Fos in cyclosporine and angiotensin II treated human gingival fibroblast cells. We found that angiotensin II in combination with cyclosporine induces c-Jun and c-Fos expressions significantly; however, the angiotensin II antagonist losartan inhibits the expression of c-Jun and c-Fos (p < 0.01). The data suggest that angiotensin II in… More >

Chan RL

Phyton-International Journal of Experimental Botany, Vol.78, pp. 5-10, 2009, DOI:10.32604/phyton.2009.78.005

Abstract Transcription factors (TFs) are proteins able to specifically recognize DNA sequences in the regulatory regions of their target genes. They bind these specific sequences, an event that leads to the activation or repression of whole signal transduction pathways. In plants about 1500 TFs were informatically identified; identification was mainly based in the presence of DNA-binding domains in the translated sequences. They were classified in families and subfamilies according to several features, including the conservation of the DNA binding domain, the genes structures and the functions they exert. Among transcription factors, several seem to be potential powerful biotechnological tools to improve… More >