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  • Open Access

    ARTICLE

    RESEARCH ON BUILDING GLAZED TILE OF FLY ASH ADDED BY RADIATION HEAT TREATMENT INSIDE CATALYTIC COMBUSTION FURNACE OF NATURAL GAS

    Shihong Zhang* , Xu Fan

    Frontiers in Heat and Mass Transfer, Vol.14, No.1, pp. 1-6, 2020, DOI:10.5098/hmt.14.9

    Abstract This article discussed compressive strength, water absorption, thermal conductivity and Frost resistance of building glazed tile of fly ash added in order to solve the problem of shortage of raw materials in the production. According to the technology of catalytic combustion furnace, glazed tiles of fly ash added with pure solid texture and glamorous colors were obtained by radiation heat treatment. It also greatly reduced pollutant emissions. The suitable proportion is about 30% of fly ash from these tests and the molding pressure is 20MPa. The utilization of fly ash not only alleviates the environmental pollution, but also saves raw… More >

  • Open Access

    ARTICLE

    COMPARISON OF BOG TREATMENT TECHNOLOGY IN LNG STATION WITHOUT LNG OUTPUT

    Rongge Xiaoa,* , Zheng Daia, Yue Zhub , Leyuan Suna , Hao Lia , Haiwei Linc

    Frontiers in Heat and Mass Transfer, Vol.14, No.1, pp. 1-5, 2020, DOI:10.5098/hmt.14.2

    Abstract In order to select economical and reasonable Boil-off gas (BOG) treatment technology for different types of liquefied natural gas (LNG) stations, this paper introduces the related technologies of BOG treatment without LNG Output. Using the same working fluid and operating parameters to simulate then the six technologies of pulse tube cryocooler recovery, liquid nitrogen recovery, nitrogen expansion recovery, jet refrigeration recovery, mixed refrigerant refrigeration recovery, and direct compression process were compared in terms of power consumption, economy. On the basis of comparative analysis of power consumption, the actual usage of the above process, and with the payback period as the… More >

  • Open Access

    ARTICLE

    Reflection on Psychological Services in Oncology and Palliative Care in Two Montreal University Hospital Centers

    Réflexion sur l’offre de services psychologiques en oncologie et soins palliatifs dans deux centres hospitaliers universitaires montréalais

    C. Defer, M.-S. Bernatchez

    Psycho-Oncologie, Vol.16, No.1, pp. 212-217, 2022, DOI:10.3166/pson-2022-0184

    Abstract In the face of cancer and at the end of life, emotional distress is common and is increasingly recognized, resulting in a significant number of requests for consultation with our specialized psychological services. The authors present a reflection on the various factors that guide their interventions with oncology and palliative care patients in a hospital setting. The challenge is to offer the right care at the right time to all patients and their loved ones who need it. The treatment plan will be adjusted according to the severity and the nature of the distress, the need to intervene within a… More >

  • Open Access

    ARTICLE

    Genome-Wide Analysis of the KANADI Gene Family and Its Expression Patterns under Different Nitrogen Concentrations Treatments in Populus trichocarpa

    Minghui Niu1,#, Heng Zhang1,#, Xiangyang Li1, Zhibao Hu1, Hongjiao Zhang2,3, Zhiru Xu2,3, Chunpu Qu1,4,*, Guanjun Liu1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 2001-2015, 2023, DOI:10.32604/phyton.2023.029350

    Abstract KANADI (KAN) is a plant-specific gene that controlled the polarity development of lateral organs. It mainly acted on the abaxial characteristics of plants to make the lateral organs asymmetrical. However, it had been less identified in woody plants. In this study, the members of the KAN gene family in Populus trichocarpa were identified and analyzed using the bioinformatics method. The results showed that a total of 8 KAN family members were screened out, and each member contained the unique GARP domain and conserved region of the family proteins. Phylogenetic analysis and their gene structures revealed that all KAN genes from… More >

  • Open Access

    ARTICLE

    Impact of Precariousness and Perceived Social Support, on the Return to Work of Women with Breast Cancer, in the Year Following the Beginning of Adjuvant Treatments

    Influence de la précarité sociale et du soutien social perçu, sur le retour au travail des femmes ayant un cancer du sein, dans l’année suivant le début des traitements adjuvants

    B. Porro, A. Michel, F. Cousson-Gélie

    Psycho-Oncologie, Vol.16, No.2, pp. 273-281, 2022, DOI:10.3166/pson-2022-0181

    Abstract The aim is to assess the associations between social precariousness, perceived social support, and the return to work (RTW) in the first year following the beginning of adjuvant breast cancer treatment. Sixty-eight breast cancer patients encountered when starting their adjuvant treatment (T0) were followed up at 3 (T1) and 12 months (T2). Friends’ informative support at T0 favours the RTW at T1. Precariousness and negative support at T0 and T2 decrease the likelihood of RTW at T2. RTW support should be offered and tailored at the outset of treatment.

    Résumé
    L’objectif est d’étudier les liens entre précarité sociale, soutien… More >

  • Open Access

    REVIEW

    Review and prospect of immune checkpoint blockade therapy represented by PD-1/PD-L1 in the treatment of clear cell renal cell carcinoma

    WENFEI GE1,#, SHIYAN SONG1,#, XIAOCHEN QI1,#, FENG CHEN1,#, XIANGYU CHE1, YONGHAO SUN1, JIN WANG1, XIAOWEI LI2, NANA LIU3, QIFEI WANG1,*, GUANGZHEN WU1,*

    Oncology Research, Vol.31, No.3, pp. 255-270, 2023, DOI:10.32604/or.2023.027942

    Abstract As a common tumor of the urinary system, the morbidity and mortality related to renal carcinoma, are increasing annually. Clear cell renal cell carcinoma (CCRCC) is the most common subtype of renal cell carcinoma, accounting for approximately 75% of the total number of patients with renal cell carcinoma. Currently, the clinical treatment of ccRCC involves targeted therapy, immunotherapy, and a combination of the two. In immunotherapy, PD-1/PD-L1 blocking of activated T cells to kill cancer cells is the most common treatment. However, as treatment progresses, some patients gradually develop resistance to immunotherapy. Meanwhile, other patients experience great side effects after… More > Graphic Abstract

    Review and prospect of immune checkpoint blockade therapy represented by PD-1/PD-L1 in the treatment of clear cell renal cell carcinoma

  • Open Access

    ARTICLE

    Bioinformatic analysis of lncRNA-associated competing endogenous RNA regulatory networks in synovial tissue of temporomandibular joint osteoarthritis

    CHUYAO WANG1,2,#, CHUAN LU2,#, LUXIANG ZOU2,*, DONGMEI HE2,*

    BIOCELL, Vol.47, No.6, pp. 1293-1306, 2023, DOI:10.32604/biocell.2023.028199

    Abstract Background: Temporomandibular joint osteoarthritis (TMJOA) is an end-stage disease that seriously affects the patients’ quality of life. Molecular insights in advancing our understanding of TMJOA are the need of the hour. Methods: We performed RNA high-throughput sequencing and bioinformatics analysis of differentially expressed (DE) long non-coding RNA (lncRNAs), microRNAs (miRNAs), and messenger RNA (mRNAs) in human synovial TMJOA tissues. Firstly, synovium samples of TMJOA patients and non-TMJOA controls were collected for highthroughput sequencing of lncRNAs, miRNAs, and mRNAs. We then performed biological function analysis of the top 100 mRNAs with more than 2-fold differential expression, and their upstream regulated miRNAs… More >

  • Open Access

    ARTICLE

    Exploring the mechanisms of magnolol in the treatment of periodontitis by integrating network pharmacology and molecular docking

    DER-JEU CHEN, CHENG-HUNG LAI*

    BIOCELL, Vol.47, No.6, pp. 1317-1327, 2023, DOI:10.32604/biocell.2023.028883

    Abstract Background: Magnolol, a bioactive extract of the Chinese herb Magnolia officinalis has a protective effect against periodontitis. This study is aimed to explore the mechanisms involved in the functioning of magnolol against periodontitis and provide a basis for further research. Methods: Network pharmacology analysis was performed based on the identification of related targets from public databases. The Protein-protein interaction (PPI) network was constructed to visualize the significance between the targets of magnolol and periodontitis. Subsequently, Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed to predict the functions and the signal regulatory pathways involved in… More >

  • Open Access

    ARTICLE

    Proteomics analysis provides novel biomarkers and therapeutic target candidates in the treatment of the Huang-Pu-Tong-Qiao formula in an AD rat model

    QIAN CHEN1,#, XIN LEI1,#, GUANHUA HU1,#, YAN WANG2, ZHENGQING FANG1, GUOQUAN WANG1, HANG SONG1, SHU YE1,*, BIAO CAI1,*

    BIOCELL, Vol.47, No.6, pp. 1265-1277, 2023, DOI:10.32604/biocell.2023.028811

    Abstract Background: Huang-Pu-Tong-Qiao formula (HPTQ), a traditional Chinese herbal formula, has a variety of pharmacological effects. It has been used to treat Alzheimer’s disease (AD) for decades. This study aimed to screen differentially expressed proteins in the hippocampus of AD model rats treated with HPTQ. Proteomic studies of the effects of HPTQ on AD are key to understanding the therapeutic mechanisms of HPTQ and identifying potential therapeutic targets. Methods: We hence used the isobaric tags for relative and absolute quantification (ITRAQ) approach to investigate the differentially expressed proteins in the hippocampus of AD model rats before and after HPTQ administration and… More >

  • Open Access

    ARTICLE

    Managing Health Treatment by Optimizing Complex Lab-Developed Test Configurations: A Health Informatics Perspective

    Uzma Afzal1, Tariq Mahmood2, Ali Mustafa Qamar3,*, Ayaz H. Khan4,5

    CMC-Computers, Materials & Continua, Vol.75, No.3, pp. 6251-6267, 2023, DOI:10.32604/cmc.2023.037653

    Abstract A complex Laboratory Developed Test (LDT) is a clinical test developed within a single laboratory. It is typically configured from many feature constraints from clinical repositories, which are part of the existing Laboratory Information Management System (LIMS). Although these clinical repositories are automated, support for managing patient information with test results of an LDT is also integrated within the existing LIMS. Still, the support to configure LDTs design needs to be made available even in standard LIMS packages. The manual configuration of LDTs is a complex process and can generate configuration inconsistencies because many constraints between features can remain unsatisfied.… More >

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