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  • Open Access

    ARTICLE

    Examination of camptothecin and 10-hydroxycamptothecin in Camptotheca acuminata plant and cell culture, and the affected yields under several cell culture treatments

    YAN PI1, KEJI JIANG2, RONG HOU1, YIFU GONG3, JUAN LIN1, XIAOFEN SUN1, AND KEXUAN TANG1,4*

    BIOCELL, Vol.34, No.3, pp. 139-144, 2010, DOI:10.32604/biocell.2010.34.139

    Abstract Camptothecin and its derivatives are monoterpenoid indole alkaloids exhibiting significant anti-tumor actions. With the aim of improving the production of these pharmaceuticals, the contents of camptothecin and 10-hydroxycamptothecin in different tissues including roots, stems, leaves, young flower buds, opening flowers, fading flowers and seeds from Camptotheca acuminata, were investigated. The young flower buds had the highest alkaloid concentrations (camptothecin, 2.46 mg/g of dry weight; 10- hydroxycamptothecin, 1.41 mg/g of dry weight). Callus showed lower concentrations but it should also be considered as a potential source of these pharmaceuticals. In the present study, the growth rate of Camptotheca acuminata cells in… More >

  • Open Access

    ARTICLE

    Agmatine pretreatment protects retinal ganglion cells (RGC-5 cell line) from oxidative stress in vitro

    IIZUKA YOKO1, SAMIN HONG2, CHAN YUN KIM2, SEUNG KAB KIM2, GONG JE SEONG2

    BIOCELL, Vol.32, No.3, pp. 245-250, 2008, DOI:10.32604/biocell.2008.32.245

    Abstract Agmatine, 2-(4-aminobutyl)guanidine, has been reported to have neuroprotective effects against various neuronal damages. In this study it was investigated whether agmatine pretreatment rescues the retinal ganglion cells from oxidative injury in vitro. After differentiation of transformed rat retinal ganglion cells (RGC-5 cell line) with staurosporine, agmatine (0.0 to 100.0 μM) pretreatment was performed for 2 hours. Subsequently, they were exposed to hydrogen peroxide (0.0 to 2.5 mM) as an oxidative stress. Cell viability was monitored for up to 48 hours with the lactate dehydrogenase (LDH) assay and apoptosis was examined by the terminal deoxynucleotide transferase-mediated terminal uridine deoxynucleotidyl transferase nick… More >

  • Open Access

    ARTICLE

    Study of the myenteric and submucous plexuses after BAC treatment in the intestine of rats

    NILZA CRISTINA BUTTOW, MIRIAM SANTIN, LUCIANA CONCI MACEDO, ALINE CRISTINA NERES TEIXEIRA, GISELE CAROLINE NOVAKOWSKI, TAÍSE ROBERTA BOLONHEIS ARMELIN, KATHYA ASSMANN

    BIOCELL, Vol.28, No.2, pp. 135-142, 2004, DOI:10.32604/biocell.2004.28.135

    Abstract A morphological and quantitative study in the ileal and colonic myenteric and submucous plexuses of rats after BAC denervation was performed. Four groups were employed: SI – ileum control; CBI – denervated ileum; SC – colon control; and CBC – denervated colon. We used the Myosin-V immunohistochemistry technique to study the myenteric and submucous plexuses. In the submucous plexus of the ileum and colon there was not a significant decrease in the number of neurons/mm2 and of ganglia/mm2 . The denervation of the myenteric plexus in the group CBI was 44.7% and in the group CBC, 68.3%. In the myenteric… More >

  • Open Access

    ARTICLE

    Biofilter efficiency of Eichhornia crassipes in wastewater treatment of fish farming in Amazonia

    Rubim MAL1, PR Isolino Sampaio1, P Parolin2,3

    Phyton-International Journal of Experimental Botany, Vol.84, No.1, pp. 244-251, 2015, DOI:10.32604/phyton.2015.84.244

    Abstract Fish is a very important part of the human diet in Amazonia. Near the growing cities, fish populations and individual size have decreased over the past decades. Alternatives to traditional and industrial fishing arise, including fish farming. Strategies to minimize the impact of fish farms on the environment are needed to have a regular and healthy fish supply. This is to avoid a reduction of biodiversity, a depletion of natural resources, and/or the induction of significant changes in the structure and functioning of adjacent ecosystems. Very little research has been performed on management of effluents as to maintain the quality… More >

  • Open Access

    ARTICLE

    Ethnobotanical survey of medicinal plants used in treatment of ticks

    Magwede K1, MP Tshisikhawe1, D Luseba2, RB Bhat1

    Phyton-International Journal of Experimental Botany, Vol.83, pp. 155-165, 2014, DOI:10.32604/phyton.2014.83.155

    Abstract The documentation of traditional knowledge on medicinal use of plants has provided many important drugs that are used worldwide on a daily basis. Traditional remedies had been (and still are) the main source of livestock ailment treatments, especially in regions of poor resources of the Vhembe District, South Africa. In many rural areas of the Republic of South Africa, traditional medicine is sometimes the only available modern orthodox health care for managing both human and animal health. Much work remains to be done regarding the documentation of the existing ethnobotanical knowledge. In this work, we report an inventory list of… More >

  • Open Access

    ARTICLE

    Liquid compost factor: a biologically derived seed treatment for increased grain chickpea production

    Robles-Hernández1* L, AC González-Franco1, SO Guy2, WC Chun2

    Phyton-International Journal of Experimental Botany, Vol.78, pp. 129-134, 2009, DOI:10.32604/phyton.2009.78.129

    Abstract This study presents the effect of Liquid Compost Factor (LCF) seed treatments on plant height in greenhouse trials, and plant density, plant height and seed yield of chickpea in field conditions. The greenhouse trials were organized in a randomized block design, while in field experiments were established in a factorial complete randomized block design conducted in Moscow and Genesee, Idaho, USA locations during 2003 and 2004. In the greenhouse, LCF 1:64 had the highest plant growth, and was statistically similar to LCF 1:110, LCF 1:128 and LCF 1:140, but different to the non-treated control. The orthogonal contrasts of LCF treatments… More >

  • Open Access

    ABSTRACT

    Virtual Implantation of Stent-graft by Finite Element Simulation and Its Applications in Endovascular Treatment Planning for B Type Aortic Dissection

    Zhuanyuan Meng1, Tao Ma2, Zhihui Dong2, Shengzhang Wang1,*, Weiguo Fu2

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 60-60, 2019, DOI:10.32604/mcb.2019.07253

    Abstract Thoracic endovascular aortic repair has been widely applied to treat Stanford Type B aortic dissection. However, retrograde type A dissection can occur as a complication after thoracic endovascular repair for Stanford type B aortic dissection. In order to investigated the possible mechanical reasons of the new entry occurring when stent grafts were implanted into the true lumen of one type B aortic dissection, a framework of virtual implantation of stent-graft by using finite element simulations was developed in this paper. The animal experiments were adopted to verify the finite element simulation of stent-graft implantation. Moreover, the manufactured stent-grafts were implanted… More >

  • Open Access

    ABSTRACT

    Role of Intracoronary OCT in Diagnosis and Treatment of Acute Coronary Syndrome

    Haibo Jia1,*, Bo Yu1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 23-24, 2019, DOI:10.32604/mcb.2019.05708

    Abstract Coronary angiography is the traditional standard imaging modality for visual evaluation of coronary anatomy and guidance of percutaneous coronary interventions (PCI). However, the 2-dimensional lumenogram cannot depict the arterial vessel per se and plaque characteristics, or directly assess the stenting result. Intracoronary imaging by means of intravascular ultrasound (IVUS) and optical coherence tomography (OCT) provides valuable incremental information that can be used clinically to optimize stent implantation and thereby minimize stent-related problems. Beyond guidance of stent selection and optimisation, imaging provides critical insights into the pathophysiology of acute coronary syndrome (ACS), greater clarity when confronted with angiographically ambiguous lesions and… More >

  • Open Access

    ARTICLE

    Post-treatment with plant extracts used in Brazilian folk medicine caused a partial reversal of the antiproliferative effect of glyphosate in the Allium cepa test

    VIVIANE DAL-SOUTO FRESCURA1, ANDRIELLE WOUTERS KUHN1, HAYWOOD DAIL LAUGHINGHOUSE IV2, JUÇARA TEREZINHA PARANHOS1, SOLANGE BOSIO TEDESCO1

    BIOCELL, Vol.37, No.2, pp. 23-28, 2013, DOI:10.32604/biocell.2013.37.023

    Abstract Species of the genus Psychotria are used for multiple purposes in Brazilian folk medicine, either as water infusions, baths or poultices. This study was aimed to evaluate the genotoxic and antiproliferative effects of infusions of Psychotria brachypoda and P. birotula on the Allium cepa test. Exposure to distilled water was used as a negative control, while exposure to glyphosate was used as a positive control. The interaction of extracts (as a post-treatment) with the effects of glyphosate was also studied. Results showed that glyphosate and the extracts of both P. brachypoda and P. birotula reduced the mitotic index as compared… More >

  • Open Access

    ARTICLE

    Experimental Study of Shot Peening Followed by Cold Spray Coating on Residual Stresses of the Treated Parts

    R. Ghelichi1, S. Bagherifard1, I. Fernandez Parienete2, M.Guagliano1,3, Simone Vezzù4

    Structural Durability & Health Monitoring, Vol.6, No.1, pp. 17-30, 2010, DOI:10.3970/sdhm.2010.006.017

    Abstract Coating deposition processes such as cold spraying are commonly employed to increase wear and fatigue resistance and consequently to enhance longevity of engineering components. Such processes typically introduce residual stresses into the coated surface, which in turn affect efficiency of coatings and play an important role in coating durability. In fact residual stresses are the key parameter to obtain compact and well-adherent coatings. They can modify several coating properties such as adhesion, structure, toughness, hardness reflecting on the macroscopic chemical and mechanical behavior of the coating.
    Present study describes alteration of residual stress state of two types of aluminum coatings… More >

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