LU SUN^1,2, HUAICHENG TAN¹, TING YU³, RUICHAO LIANG^4,*

Oncology Research, Vol.31, No.6, pp. 967-988, 2023, DOI:10.32604/or.2023.042309

Abstract Lung adenocarcinoma (LUAD) is the most common and deadliest subtype of lung cancer. To select more targeted and effective treatments for individuals, further advances in classifying LUAD are urgently needed. The number, type, and function of T cells in the tumor microenvironment (TME) determine the progression and treatment response of LUAD. Long noncoding RNAs (lncRNAs), may regulate T cell differentiation, development, and activation. Thus, our aim was to identify T cell-related lncRNAs (T cell-Lncs) in LUAD and to investigate whether T cell-Lncs could serve as potential stratifiers and therapeutic targets. Seven T cell-Lncs were identified to further establish the T… More >

Muhammad Irfan¹, Ahmad Shaf^2,*, Tariq Ali², Umar Farooq², Saifur Rahman¹, Salim Nasar Faraj Mursal¹, Mohammed Jalalah¹, Samar M. Alqhtani³, Omar AlShorman⁴

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 711-729, 2023, DOI:10.32604/cmc.2023.038176

Abstract A brain tumor is a mass or growth of abnormal cells in the brain. In children and adults, brain tumor is considered one of the leading causes of death. There are several types of brain tumors, including benign (non-cancerous) and malignant (cancerous) tumors. Diagnosing brain tumors as early as possible is essential, as this can improve the chances of successful treatment and survival. Considering this problem, we bring forth a hybrid intelligent deep learning technique that uses several pre-trained models (Resnet50, Vgg16, Vgg19, U-Net) and their integration for computer-aided detection and localization systems in brain tumors. These pre-trained and integrated… More >

R. D. Dhaniya¹, K. M. Umamaheswari^2,*

Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 1129-1143, 2023, DOI:10.32604/iasc.2023.035905

Abstract Current revelations in medical imaging have seen a slew of computer-aided diagnostic (CAD) tools for radiologists developed. Brain tumor classification is essential for radiologists to fully support and better interpret magnetic resonance imaging (MRI). In this work, we reported on new observations based on binary brain tumor categorization using HYBRID CNN-LSTM. Initially, the collected image is pre-processed and augmented using the following steps such as rotation, cropping, zooming, CLAHE (Contrast Limited Adaptive Histogram Equalization), and Random Rotation with panoramic stitching (RRPS). Then, a method called particle swarm optimization (PSO) is used to segment tumor regions in an MR image. After… More >

Amarendra Reddy Panyala^1,2, M. Baskar^3,*

Computer Systems Science and Engineering, Vol.46, No.3, pp. 3883-3899, 2023, DOI:10.32604/csse.2023.037050

Abstract The deep learning models are identified as having a significant impact on various problems. The same can be adapted to the problem of brain tumor classification. However, several deep learning models are presented earlier, but they need better classification accuracy. An efficient Multi-Feature Approximation Based Convolution Neural Network (CNN) model (MFA-CNN) is proposed to handle this issue. The method reads the input 3D Magnetic Resonance Imaging (MRI) images and applies Gabor filters at multiple levels. The noise-removed image has been equalized for its quality by using histogram equalization. Further, the features like white mass, grey mass, texture, and shape are… More >

Muhammed Mutlu Yapici¹, Rukiye Karakis^2,*, Kali Gurkahraman³

CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5049-5067, 2023, DOI:10.32604/cmc.2023.035584

Abstract Deep learning (DL) techniques, which do not need complex pre-processing and feature analysis, are used in many areas of medicine and achieve promising results. On the other hand, in medical studies, a limited dataset decreases the abstraction ability of the DL model. In this context, we aimed to produce synthetic brain images including three tumor types (glioma, meningioma, and pituitary), unlike traditional data augmentation methods, and classify them with DL. This study proposes a tumor classification model consisting of a Dense Convolutional Network (DenseNet121)-based DL model to prevent forgetting problems in deep networks and delay information flow between layers. By… More >

Abishek Mahesh¹, Deeptimaan Banerjee¹, Ahona Saha¹, Manas Ranjan Prusty^2,*, A. Balasundaram²

CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5967-5982, 2023, DOI:10.32604/cmc.2023.033920

Abstract A brain tumor is the uncharacteristic progression of tissues in the brain. These are very deadly, and if it is not diagnosed at an early stage, it might shorten the affected patient’s life span. Hence, their classification and detection play a critical role in treatment. Traditional Brain tumor detection is done by biopsy which is quite challenging. It is usually not preferred at an early stage of the disease. The detection involves Magnetic Resonance Imaging (MRI), which is essential for evaluating the tumor. This paper aims to identify and detect brain tumors based on their location in the brain. In… More >

Abdullah A. Asiri¹, Bilal Khan², Fazal Muhammad^3,*, Shams ur Rahman⁴, Hassan A. Alshamrani¹, Khalaf A. Alshamrani¹, Muhammad Irfan⁵, Fawaz F. Alqhtani¹

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 299-312, 2023, DOI:10.32604/iasc.2023.032426

Abstract In the medical profession, recent technological advancements play an essential role in the early detection and categorization of many diseases that cause mortality. The technique rising on daily basis for detecting illness in magnetic resonance through pictures is the inspection of humans. Automatic (computerized) illness detection in medical imaging has found you the emergent region in several medical diagnostic applications. Various diseases that cause death need to be identified through such techniques and technologies to overcome the mortality ratio. The brain tumor is one of the most common causes of death. Researchers have already proposed various models for the classification… More >

Abdullah A. Asiri¹, Ahmad Shaf^2,*, Tariq Ali², Muhammad Aamir², Ali Usman², Muhammad Irfan³, Hassan A. Alshamrani¹, Khlood M. Mehdar⁴, Osama M. Alshehri⁵, Samar M. Alqhtani⁶

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 127-143, 2023, DOI:10.32604/iasc.2023.032391

Abstract The brain tumor is an abnormal and hysterical growth of brain tissues, and the leading cause of death affected patients worldwide. Even in this technology-based arena, brain tumor images with proper labeling and acquisition still have a problem with the accurate and reliable generation of realistic images of brain tumors that are completely different from the original ones. The artificially created medical image data would help improve the learning ability of physicians and other computer-aided systems for the generation of augmented data. To overcome the highlighted issue, a Generative Adversarial Network (GAN) deep learning technique in which two neural networks… More >

Ziquan Zhu¹, Muhammad Attique Khan², Shui-Hua Wang¹, Yu-Dong Zhang^1,*

CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 101-111, 2023, DOI:10.32604/cmc.2023.030790

Abstract Brain tumor refers to the formation of abnormal cells in the brain. It can be divided into benign and malignant. The main diagnostic methods for brain tumors are plain X-ray film, Magnetic resonance imaging (MRI), and so on. However, these artificial diagnosis methods are easily affected by external factors. Scholars have made such impressive progress in brain tumors classification by using convolutional neural network (CNN). However, there are still some problems: (i) There are many parameters in CNN, which require much calculation. (ii) The brain tumor data sets are relatively small, which may lead to the overfitting problem in CNN.… More >

P. P. Fathimathul Rajeena^1,*, R. Sivakumar²

Intelligent Automation & Soft Computing, Vol.35, No.3, pp. 2837-2855, 2023, DOI:10.32604/iasc.2023.030144

Abstract An accurate and early diagnosis of brain tumors based on medical imaging modalities is of great interest because brain tumors are a harmful threat to a person’s health worldwide. Several medical imaging techniques have been used to analyze brain tumors, including computed tomography (CT) and magnetic resonance imaging (MRI). CT provides information about dense tissues, whereas MRI gives information about soft tissues. However, the fusion of CT and MRI images has little effect on enhancing the accuracy of the diagnosis of brain tumors. Therefore, machine learning methods have been adopted to diagnose brain tumors in recent years. This paper intends… More >