Mario D’Ambrosio¹, Elisabetta Bigagli^1,*, Lorenzo Cinci¹, Cecilia Brunetti^2,*, Edgardo Giordani³, Francesco Ferrini³, Cristina Luceri¹

Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.073250 - 30 January 2026

Abstract Moringa oleifera (MO) is traditionally used to mitigate inflammatory-mediated disorders; however, the influence of ecotypic variation on its anti-inflammatory activity remains poorly understood. In this study, we compared the phytochemical composition and anti-inflammatory activity of ethanolic extracts obtained from fresh and dried leaves of four MO ecotypes (India, Paraguay, Mozambique, and Pakistan), all grown under the same outdoor conditions, as well as two commercial powders (Just Moringa and WISSA), using LPS-stimulated RAW 264.7 macrophages. Extracts from fresh leaves were 19–43% more cytotoxic than those from dried leaves, depending on the ecotype, likely due to higher cyanogenic… More >

Chee Chin Lim^1,2,*, Hui Wen Tiu¹, Qi Wei Oung^1,3, Chiew Chea Lau⁴, Xiao Jian Tan^2,5

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.070468 - 12 January 2026

Abstract Breast cancer remains one of the leading causes of cancer mortality world-wide, with accurate molecular subtyping is critical for guiding treatment and improving patient outcomes. Traditional molecular subtyping via immuno-histochemistry (IHC) test is invasive, time-consuming, and may not fully represent tumor heterogeneity. This study proposes a non-invasive approach using digital mammography images and deep learning algorithm for classifying breast cancer molecular subtypes. Four pretrained models, including two Convolutional Neural Networks (MobileNet_V3_Large and VGG-16) and two Vision Transformers (ViT_B_16 and ViT_Base_Patch16_Clip_224) were fine-tuned to classify images into HER2-enriched, Luminal, Normal-like, and Triple Negative subtypes. Hyperparameter tuning,… More >

Elizabeth Martinez¹, Ana K. Escalera-Ordaz¹, Francisco J. Espinosa-García², Yolanda M. García-Rodríguez², Rafael Ariza-Flores³, Javier Ponce-Saavedra⁴, Patricio Apáez-Barrios⁵, Héctor Guillén-Andrade^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4155-4171, 2025, DOI:10.32604/phyton.2025.073438 - 29 December 2025

Abstract Volatile organic compounds (VOCs) play an important role in plant survival and adaptation. They contribute to defense against pests and pathogens, tolerance to abiotic stress, and the mediation of essential ecological interactions such as pollination and attraction of dispersal agents. The complex mixture of VOCs produced by an organism, known as volatilome, varies across species, populations, and individuals, making VOCs a major factor in crop diversification and adaptation. In this context, characterizing the volatilome of crop genotypes can provide insight into their ecological associations and potential relationships with agronomic traits. In this study, the volatilome… More >

Helen Fenske¹, Ingrid R. Niesman^2,*

BIOCELL, Vol.49, No.12, pp. 2433-2455, 2025, DOI:10.32604/biocell.2025.071078 - 24 December 2025

Abstract Objective: Tyrosinase is the rate-limiting enzyme in the generation of melanin. The feline tyrosinase mutation, G302R, confers temperature-sensitive loss of function, resulting in the familiar Siamese cat phenotype. Crystal or cryoEM structures are elusive for any mammalian tyrosinase to date. Protein misfolding is suggested as a basis for phenotypes resulting from mutant tyrosinases, but this hypothesis needs structural confirmation. Our objective for this study is to confirm misfolding of mutant tyrosinase as a basis for temperature-sensitive phenotypes compared to catalytic dysfunction that may be responsible for other tyrosinase mutant breed phenotypes. Methods: We have employed… More >

Erping Song^1,*, Zipin Yao²

Energy Engineering, Vol.122, No.12, pp. 5129-5147, 2025, DOI:10.32604/ee.2025.063827 - 27 November 2025

Abstract Wind farm layout optimization is a critical challenge in renewable energy development, especially in regions with complex terrain. Micro-siting of wind turbines has a significant impact on the overall efficiency and economic viability of wind farm, where the wake effect, wind speed, types of wind turbines, etc., have an impact on the output power of the wind farm. To solve the optimization problem of wind farm layout under complex terrain conditions, this paper proposes wind turbine layout optimization using different types of wind turbines, the aim is to reduce the influence of the wake effect… More >

Su Jin Shin¹, Sang Uk Shin^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2787-2819, 2025, DOI:10.32604/cmes.2025.072602 - 26 November 2025

Abstract To reconstruct vehicle accidents, data from the time of the incident—such as pre-collision speed and collision point—is essential. This data is collected and generated through various sensors installed in the vehicle. However, it may contain sensitive information about the vehicle owner. Consequently, vehicle owners tend to be reluctant to provide their vehicle data due to concerns about personal information exposure. Therefore, extensive research has been conducted on secure vehicle data trading models. Existing models primarily utilize centralized approaches, leading to issues such as single points of failure, data leakage, and manipulation. To address these problems,… More >

Ivica Delic¹, Goran Jukic², Ivan Varnica², Valentina Spanic^3,*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3189-3203, 2025, DOI:10.32604/phyton.2025.070489 - 29 October 2025

Abstract This study evaluated agro-morphological traits, grain quality traits, and phenotypic stability of nine soybean genotypes across four environments over two growing seasons (2022–2023). Traits such as days to flowering, days to maturity, and disease symptoms were monitored throughout the season. At maturity, parameters including grain yield, grain oil and protein content, 1000-seed weight, test weight, scores of lodgings, shattering, plant height, and first pod height were evaluated. In addition, 18 morphological traits were scored, of which eight were sufficiently variable for further analysis. In terms of environmental stability, genotypes 2 and 13 excelled, while genotypes… More >

Heng Zhang^1,#, Meng Wang^1,#, Dong Zeng^1,2, Yunbo Xu¹, Dongyuan Guo¹, Xuanchen Liu^1,3, Zhanqi Ren⁴, Jinzi Zhang¹, Yuhang Liu¹, Qiuyu Wang¹, Shuo Yu¹, Guanzheng Qu^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3205-3216, 2025, DOI:10.32604/phyton.2025.069994 - 29 October 2025

Abstract Hybridization remains an important method for breeding new poplar varieties. It results in significant variation in leaf phenotype among parents and offspring, and among offspring themselves. This study aimed to investigate whether leaf shape variations were similar in offspring produced from reciprocal crosses. Specifically, two hybrid combinations were produced: the direct cross with Populus ussuriensis as the maternal parent and P. simonii × P. nigra as the paternal parent (HY53), and the reciprocal cross with P. simonii × P. nigra as the maternal parent and P. ussuriensis as the paternal parent (HY268). Using 3-month-old rooted cuttings from 40 clones (36 F₁ hybrids… More >

Andreea Moldovan¹, Ioana Moldovan^2,*, Lukács Lehel², Antonia Odagiu³, Lucia Draghia⁴, Maria Cantor^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2767-2779, 2025, DOI:10.32604/phyton.2025.069324 - 30 September 2025

Abstract Pelargonium zonale is an important ornamental and medicinal plant. The purpose of this investigation was to evaluate the effects of conventional and unconventional fertilization on variations in the physicochemical parameters of the culture substrate (temperature, pH, and electrical conductivity) in two cultivars of Pelargonium zonale (L.) L’Hér., grown in pots. This study was conducted under greenhouse conditions, using Pindstrup peat as the culture substrate. The analysis focused on how these physicochemical indicators of peat influenced plant height and development under fertilization conditions. Results revealed that in the ‘Tango Salmon’ cultivar, both fertilization regimes significantly modified substrate temperature… More >

Yongting Duan^*Chengcheng Zhu

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.010514

Abstract Clarify the mechanical properties of different laminations and the fracture mechanism of continental shale under in-situ stress can provide theoretical basis for more comprehensive evaluation of the fracability of continental shale oil reservoir. The Chang 72 continental shale was used to investigate the mechanical properties of laminations and the effect of natural structure on the crack propagation of the shale. The X-ray diffraction (XRD) and thin section tests show that the laminations contain two types: bright sandy lamination with void structure and dark muddy lamination with layer structure. The real-time Computed Tomography (CT) uniaxial compression… More >