Wenchao Shi¹, Tao Wei², Chuan Yang³, Qichao Fan³, Hongxi Liu⁴, Bin Shao^5,*, Peng Jing^4,*

CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2026.075293

Abstract Enhancing the strength of nanotwinned aluminum (Al) is essential for the development of next-generation high-end chip technology. To better understand the detwinning behavior of nanotwinned Al under conditions with no resolved shear stress acting on the twin boundaries, we conducted molecular dynamics simulations of uniaxial tensile deformation in nanotwinned single-crystal Al at room temperature. Detwinning is observed only when the twin boundary spacing is 7.01 Å. At larger spacings, twin boundaries remain parallel to the loading direction, with no rotation or bending, indicating negligible migration. Detwinning is triggered by localized stress from dislocation interactions, with More >

Qi Wang, Kelvin Amos Nicodemas^*

CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2026.074305

Abstract Multivariate time series forecasting plays a crucial role in decision-making for systems like energy grids and transportation networks, where temporal patterns emerge across diverse scales from short-term fluctuations to long-term trends. However, existing Transformer-based methods often process data at a single resolution or handle multiple scales independently, overlooking critical cross-scale interactions that influence prediction accuracy. To address this gap, we introduce the Hierarchical Attention Transformer (HAT), which enables direct information exchange between temporal hierarchies through a novel cross-scale attention mechanism. HAT extracts multi-scale features using hierarchical convolutional-recurrent blocks, fuses them via temperature-controlled mechanisms, and optimizes More >

Guancan Liang^#, Jian Pan^#, Ruixiang Dai, Ziyi Lin, Xunbao Wang, Teng Hou, Zhicheng Luo, Xiaoming Wang^*

Canadian Journal of Urology, DOI:10.32604/cju.2026.074252

Abstract Background: The causal link between mental illness and prostatitis remains inconclusive, largely due to heterogeneity and potential confounders. This study explored the causal link between mental illness and prostatitis in men using Mendelian randomization (MR), and offered recommendations for enhancing future research. Methods: Publicly accessible genome-wide association study (GWAS) data were accessed via the IEU OpenGWAS platform and FinnGen database for this research. The inverse variance weighted (IVW) approach served as the primary Mendelian randomization analysis, while MR-Egger, weighted median, weighted mode, and simple mode methods were additionally applied to evaluate potential relationships between prostatitis… More >

Dalin Wang¹, Mingcai Zhang¹, Richard Hastings², Patrick George¹, Ryan Ranzau¹, Jinxi Wang^1,3,*

BIOCELL, DOI:10.32604/biocell.2026.074572

Abstract Objective: Although endplate (EP) injury may cause intervertebral disc (IVD) degeneration and Modic changes (MCs) in the vertebral bone marrow (VBM), EP injury-induced synchronous cellular reactions and their crosstalk in the IVD and VBM remain unclear. This protocol-based study aimed to streamline and optimize the methods of tissue harvest and cell preparation for flow cytometry (FCM) analysis of T-cell and macrophage subpopulations in both VBM and IVD adjacent to the surgically induced EP microfracture in mice. Methods: EP injury or sham procedure was performed at the spinal levels L4-5 and L5-6 in male mice. Step-by-step… More >

Kuo Li^1,2, Yue Tang^1,2, Yonggang Li^1,2,*, Yuhao Wu^1,2,*

Congenital Heart Disease, DOI:10.32604/chd.2026.076517

Abstract Background: There has been an increasing number of studies documenting the application of the right axillary thoracotomy (RAT) approach for the repair of congenital heart diseases. However, no research has reported the RAT approach in repairing the anomalous aortic origin of a coronary artery (AAOCA). This study aims to investigate the feasibility and safety of the RAT approach for repairing AAOCA in children. Methods: We performed a retrospective study at the Children’s Hospital of Chongqing Medical University between January 2024 and October 2025 to investigate the clinical outcomes of the RAT approach for repairing AAOCA in… More >

Ryan G. McQueen¹, Paulina M. Gutkin², George M. Hoffman³, Ronald K. Woods^4,*

Congenital Heart Disease, DOI:10.32604/chd.2025.075838

Abstract Objective: The objective of this study was to understand intraoperative risk factors for post-Norwood extracorporeal membrane oxygenation (ECMO) in patients with hypoplastic left heart syndrome (HLHS). Methods: We conducted a retrospective, single-institution review of all patients with HLHS who underwent a Norwood procedure (nadir cardiopulmonary bypass temperature ≤ 22°C) over a 12-year period with quantitative and qualitative analysis. Results: Of 102 Norwood patients, 14 (13.7%) required ECMO. ECMO patients had longer median cardiopulmonary bypass (CPB) times (276 vs. 172 min, p < 0.001) and myocardial ischemic times (98.5 vs 83 min, p = 0.021). Longer CPB time was More >

Yuanyuan Li¹, Xingyue Wang¹, Yucan Deng¹, Runfang Tian¹, Jinfeng Zhao¹, Li Liu^2,*, Panpan Sun^3,*, Zhiguang Ping^1,3,*

Congenital Heart Disease, DOI:10.32604/chd.2026.075611

Abstract Background: Four-dimensional (4D) ultrasound is increasingly being used for prenatal diagnosis of congenital heart disease (CHD). We aimed to perform a systematic review and meta-analysis to evaluate its diagnostic accuracy for fetal CHD. Methods: This systematic review was conducted in accordance with the PRISMA-DTA guidelines. We systematically searched eight databases for studies published up to July 22, 2025. Data were extracted to calculate diagnostic accuracy metrics, study quality was assessed using QUADAS-2, and a bivariate random-effects model was used for the meta-analysis. Results: A total of 49 studies were included, comprising 45 retrospective and 4 prospective studies,… More >

Jae Hong Lee¹, Seung Min Baek², Hye Won Kwon³, Sungkyu Cho^3,4, Jae Gun Kwak^3,4, Woong-Han Kim^3,4,5,*

Congenital Heart Disease, DOI:10.32604/chd.2025.075046

Abstract Background: We evaluated surgical outcomes of biventricular repair for atrioventricular septal defect (AVSD) with tetralogy of Fallot (TOF) or double-outlet right ventricle (DORV). Methods: This retrospective pilot study included 12 patients who underwent biventricular repair of AVSD with TOF (n = 6) or DORV (n = 6) between 2004 and 2023. Right ventricular outflow tract (RVOT) reconstruction was performed using transannular patch (TAP, n = 4) or pulmonary valve preservation (PVP, n = 8). Clinical outcomes, including longitudinal pulmonary valve growth, RVOT obstruction, and pulmonary regurgitation, were reviewed descriptively, with particular focus on the feasibility of PVP.… More >

Bryanna N. Schwartz^*, Victoria L. Pemberton, D’Andrea Freemon, Kristin M. Burns, Gail D. Pearson

Congenital Heart Disease, DOI:10.32604/chd.2025.073995

Abstract Background: In the 1990s, there were few multicenter research collaborations and pediatric cardiovascular clinical trials. The National Heart, Lung, and Blood Institute at the National Institutes of Health established the Pediatric Heart Network (PHN) in 2001 to stimulate multi-center collaboration and clinical studies in children and adults with congenital heart disease (CHD) and pediatric acquired heart disease. Methods: The PHN developed a flexible infrastructure for multi-center collaborative clinical research in children and adults with CHD and pediatric acquired heart disease. The objectives of the PHN are to improve health outcomes in individuals of all ages with… More >

Yufei Xie^1,#, Jing Wang^2,#, Qun Wu¹, Haoxuan Li², Xiaomin Duan¹, Fangyun Wang¹, Xin Zhang^1,*, Xiaofeng Li^3,*

Congenital Heart Disease, DOI:10.32604/chd.2025.073905

Abstract Uhl’s anomaly is an exceedingly rare (fewer than 1 in 1,000,000 live births) and often fatal congenital heart disease characterized by the near-complete absence of the right ventricular (RV) myocardium. Although typically considered sporadic, we report a familial case suggesting an inherited etiology. A 12-year-old boy presented with exertional chest pain and a decade-long history of an abnormal cardiac silhouette. Comprehensive imaging revealed apical RV wall thinning, aneurysmal bulging with trabeculations, and severely impaired RV function, with a Tricuspid Annular Plane Systolic Excursion (TAPSE) of 10 mm and a Fractional Area Change (FAC) of 35%.… More >