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  • Design an Artificial Neural Network by MLP Method; Analysis of the Relationship between Demographic Variables, Resilience, COVID-19 and Burnout
  • Abstract In addition to the effect that the COVID-19 pandemic has had on the physical and mental health of individuals, it has also led to a change in the mental and emotional state of many employees. Especially among businesses and private companies, which faced many restrictions due to the special conditions of the pandemic. Therefore, the present study aimed to design an artificial neural network with MLP technique to analyze the relationship between demographic variables, resilience, COVID-19 and burnout in start-ups in Iran. The research method was quantitative. Managers and employees of start-ups formed the statistical population of the study, based…
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  • A Review of Electromagnetic Energy Regenerative Suspension System & Key Technologies
  • Abstract The active suspension has undoubtedly improved the performance of the vehicle, however, the trend of “lowcarbonization, intelligence, and informationization” in the automotive industry has put forward higher and more urgent requirements for the suspension system. The automotive industry and researchers favor active energy regeneration suspension technology with safety, comfort, and high energy regenerative efficiency. In this paper, we review the research progress of the structure form, optimization method, and control strategy of electromagnetic energy regenerative suspension. Specifically, comparing the pros and cons of the existing technology in solving the contradiction between dynamic performance and energy regeneration. In addition, the development…
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  • A Ring-Reinforced Right Ventricle to Pulmonary Artery Conduit is Associated with Better Regional Mechanics after Stage I Norwood Operation
  • Abstract Background: The right ventricle to pulmonary artery conduit (RVPAC) may impair right ventricular (RV) function in patients with functional single right ventricles. Modification of the RVPAC using a ring-reinforced end with dunked insertion into the RV through a limited ventriculotomy may reduce the impact on RV function. We compared RV segmental strain between patients with a traditional RVPAC and ring-reinforced RVPAC using feature tracking cardiovascular magnetic resonance (CMR) imaging. Methods: Patients with CMR examinations after Stage I operation with RVPAC between 2000 and 2018 were reviewed. Ventricular mass, volumes, late gadolinium enhancement (LGE), and peak radial and circumferential strain of…
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  • Early Cardiac Catheterizations within 30 Days Post Congenital Heart Surgery in Children
  • Abstract Background: This study set out to assess the indications, feasibility, safety, and outcome of early cardiac catheterizations (CC) within 30 days after congenital heart surgery (CHS) in children. Methods and Results: This is a retrospective, single-center case review study of all CC within 30 days after CHS between 1/2010-12/2020. A total of 317 (138 diagnostic, 179 interventional) CC were performed in 245 patients at a median of 4 days (IQR 13) after CHS. The median age was 3 months (IQR 6), and body weight was 5 kg (IQR 4). A total of 194 (61.2%) CC were performed in patients with…
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  • NOTCH3 Mutations and CADASIL Phenotype in Pulmonary Arterial Hypertension Associated with Congenital Heart Disease
  • Abstract Background: The etiology of pulmonary arterial hypertension associated with congenital heart disease (PAHCHD) is complicated and the phenotype is heterogeneous. Genetic defects of NOTCH3 were associated with cerebral disease and pulmonary hypertension. However, the relationship between NOTCH3 mutations and the clinical phenotype has not been reported in CHD-PAH. Methods: We eventually enrolled 142 PAH-CHD patients from Fuwai Hospital. Whole exome sequencing (WES) was performed to screen the rare deleterious variants of NOTCH3 gene. Results: This PAH-CHD cohort included 43 (30.3%) men and 99 (69.7%) women with the mean age 29.8 ± 10.9 years old. The pathogenic or likely pathogenic mutations…
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  • Factors Affecting the Genetic Diagnostic Rate in Congenital Heart Disease
  • Abstract Background: Over 400 genes contribute to the development of congenital heart disease (CHD). Additionally, multisystemic manifestations accompanying syndromic CHD pose a higher risk of genetic diseases. This study investigated the diagnostic yield of whole-exome sequencing (WES) in patients with sporadic syndromic CHD and the phenotypic factors affecting the genetic diagnostic rate. Methods: Sixty-four patients with sporadic syndromic CHD aged <18 years underwent WES between May 2018 and December 2020 in a single tertiary center, and the association between genetic testing data and extracardiac phenotypes was analyzed. Results: Extracardiac phenotypes were measured as 3.66 ± 3.05 (standard deviation, interquartile range: 2–5)…
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  • Preoperative Feeding in Single Ventricle Neonates is Predictive of Shorter Time to Goal Feed
  • Abstract Background: Patients with single ventricle anatomy are at increased risk of growth failure and malnutrition. Amongst cardiac centers, there is little standardization of feeding practices in this complex population. We hypothesized that initiation of our center’s preoperative feeding protocol would result in decreased gastrostomy tube (G-tube) use, decreased length of stay and would not result in increased Necrotizing Enterocolitis (NEC) rates. Methods: A single institution review of 52 patients who had undergone stage I single ventricle palliative repair was performed. Patient diagnoses were hypoplastic left heart syndrome (39%), atrioventricular canal (15%), and other (46%). Postoperative parameters such as time to…
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  • Minimally Invasive Surgical Technique in Double Aortic Arch with Distal Atretic Left-Side in Infant: From a Single-Surgeon Clinical Experience
  • Abstract Background: Double aortic arch (DAA) with distal left-sided aortic arch atresia (LAAA) can form complete vascular ring by ligamentum connection. We aimed to introduce an uncommon DAA-LAAA diagnosis and treatment by the minimally invasive surgical technique (MIST). Methods: We retrospectively reviewed 7 cases of DAA-LAAA that were treated from January 2017 to July 2021. All infant patients underwent surgical repair by minimally invasive surgical technique. Mean follow-up was 14.43 months (range, 5–21 months). Results: There were seven patients with DAA-LAAA, including six males and one female. Median age was 19.29 months (range, 9.0–29.0 months). Median weight was 11.30 kg (range,…
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