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  • Open Access

    REVIEW

    Clinically proven natural products against breast cancer, with mechanistic insights

    MD. MAHMUDUL HASAN1,2, SHAH MD. WASIN2,3, MISHU RAHMAN2,4, EVA AZME1,2, MD. SAQLINE MOSTAQ5, MD. MAHEDI HASAN NAHID6, NOR MOHAMMAD7, FARJANA AFRIN TANJUM8, MD. ANAMUL HAQUE5, MD ASHIQ MAHMUD5,*, MOHAMMAD NURUL AMIN5,*

    Oncology Research, DOI:10.32604/or.2025.062778

    Abstract Background: Breast cancer still stands to be the foremost contributor to cancer-related incidence and mortality in women globally accounting for about 14% of all female cancer-related deaths worldwide. This research seeks to illustrate the mechanisms and clinical findings of natural products against breast cancer treatment. Methodology: Required data for this review article was retrieved employing several readily obtainable search databases, including Web of Science® (Thomson Reuters, USA), PubMed® (U.S. National Library of Medicine, USA), and SciVerse Scopus® (Elsevier Properties S.A., USA), taking into consideration certain search terms like “breast cancer,” “natural products against breast cancer,” and “Clinically… More > Graphic Abstract

    Clinically proven natural products against breast cancer, with mechanistic insights

  • Open Access

    REVIEW

    Molecular insights into immune evasion in head and neck squamous cell carcinomas: Toward a promising treatment strategy

    HYEON JI KIM1,#, BO KYUNG JOO1,#, JIN-SEOK BYUN2,3,*, DO-YEON KIM1,3,*

    Oncology Research, DOI:10.32604/or.2025.062207

    Abstract Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive and devastating disease arising primarily from the mucosal epithelium of the oral cavity, pharynx, and larynx. HNSCC ranks as the sixth most common cancer worldwide, carrying significant morbidity and mortality. HPV-positive HNSCC can be partially prevented with the FDA-approved HPV vaccine and generally exhibits a more favorable prognosis compared to HPV-negative cases. However, effective screening and treatment approaches remain elusive for HPV-negative HNSCC. While precancerous lesions may precede invasive cancer in certain situations, most patients present with advanced disease without prior indication of precancerous More >

  • Open Access

    ARTICLE

    The Relationship between Parental Phubbing and Problem Behaviors in Preschool Children

    Qiulan Gu1,2, Mei Zhao1,2,*

    International Journal of Mental Health Promotion, DOI:10.32604/ijmhp.2025.062796

    Abstract Objectives: With the widespread adoption of smartphones, parental phubbing behaviors have become increasingly prevalent, potentially affecting preschool children’s development. Current research primarily focuses on adolescent populations, while the mechanisms through which parental phubbing and authoritarian parenting style influence preschool children’s behavioral problems within the Chinese cultural context remain to be explored. Our investigation seeks to examine the factors contributing to behavioral difficulties among children of preschool age and provide theoretical guidance for prevention. Methods: In our research, we utilized a convenience sampling approach to collect data from parents whose children (n = 612) were between… More >

  • Open Access

    ARTICLE

    SRM Simulation of Thermal Convective on MHD Nanofluids across Moving Flat Plate

    Shahina Akter1,2, Muhammad Amer Qureshi3, Mohammad Ferdows1,*

    Frontiers in Heat and Mass Transfer, DOI:10.32604/fhmt.2025.062311

    Abstract This study explores free convective heat transfer in an electrically conducting nanofluid flow over a moving semi-infinite flat plate under the influence of an induced magnetic field and viscous dissipation. The velocity and magnetic field vectors are aligned at a distance from the plate. The Spectral Relaxation Method (SRM) is used to numerically solve the coupled nonlinear partial differential equations, analyzing the effects of the Eckert number on heat and mass transfer. Various nanofluids containing , , , and nanoparticles are examined to assess how external magnetic fields influence fluid behavior. Key parameters, including the More >

  • Open Access

    ARTICLE

    Numerical Analysis of the Aerodynamic Performance of an Ahmed Body Fitted with Spoilers of Different Opening Areas

    Haichao Zhou*, Wei Zhang, Tinghui Huang, Haoran Li

    FDMP-Fluid Dynamics & Materials Processing, DOI:10.32604/fdmp.2025.064991

    Abstract The configuration of a spoiler plays a crucial role in the aerodynamics of a vehicle. In particular, investigating the impact of spoiler design on aerodynamic performance is essential for effectively reducing drag and optimizing efficiency. This study focuses on the 35° Ahmed body as the test model and examines six different spoiler types mounted on its slant surface. Using the Lattice Boltzmann Method (LBM) in XFlow and the Large Eddy Simulation (LES) technique, the aerodynamic effects of these spoilers were analyzed. The numerical approach was validated against published experimental data. Results indicate that aerodynamic drag More >

  • Open Access

    ARTICLE

    Full Ceramic Bearing Fault Diagnosis with Few-Shot Learning Using GPT-2

    David He1,*, Miao He2, Jay Yoon3

    CMES-Computer Modeling in Engineering & Sciences, DOI:10.32604/cmes.2025.063975

    Abstract Full ceramic bearings are mission-critical components in oil-free environments, such as food processing, semiconductor manufacturing, and medical applications. Developing effective fault diagnosis methods for these bearings is essential to ensuring operational reliability and preventing costly failures. Traditional supervised deep learning approaches have demonstrated promise in fault detection, but their dependence on large labeled datasets poses significant challenges in industrial settings where fault-labeled data is scarce. This paper introduces a few-shot learning approach for full ceramic bearing fault diagnosis by leveraging the pre-trained GPT-2 model. Large language models (LLMs) like GPT-2, pre-trained on diverse textual data,… More >

  • Open Access

    ARTICLE

    DEMGAN: A Machine Learning-Based Intrusion Detection System Evasion Scheme

    Dawei Xu1,2,3, Yue Lv1, Min Wang1, Baokun Zheng4,*, Jian Zhao1,3, Jiaxuan Yu5

    CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2025.064833

    Abstract Network intrusion detection systems (IDS) are a prevalent method for safeguarding network traffic against attacks. However, existing IDS primarily depend on machine learning (ML) models, which are vulnerable to evasion through adversarial examples. In recent years, the Wasserstein Generative Adversarial Network (WGAN), based on Wasserstein distance, has been extensively utilized to generate adversarial examples. Nevertheless, several challenges persist: (1) WGAN experiences the mode collapse problem when generating multi-category network traffic data, leading to subpar quality and insufficient diversity in the generated data; (2) Due to unstable training processes, the authenticity of the data produced by… More >

  • Open Access

    ARTICLE

    Short-Term Electricity Load Forecasting Based on T-CFSFDP Clustering and Stacking-BiGRU-CBAM

    Mingliang Deng1, Zhao Zhang1,*, Hongyan Zhou2, Xuebo Chen2

    CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2025.064509

    Abstract To fully explore the potential features contained in power load data, an innovative short-term power load forecasting method that integrates data mining and deep learning techniques is proposed. Firstly, a density peak fast search algorithm optimized by time series weighting factors is used to cluster and analyze load data, accurately dividing subsets of data into different categories. Secondly, introducing convolutional block attention mechanism into the bidirectional gated recurrent unit (BiGRU) structure significantly enhances its ability to extract key features. On this basis, in order to make the model more accurately adapt to the dynamic changes… More >

  • Open Access

    ARTICLE

    An Optimized Unsupervised Defect Detection Approach via Federated Learning and Adaptive Embeddings Knowledge Distillation

    Jinhai Wang1, Junwei Xue1, Hongyan Zhang2, Hui Xiao3,4, Huiling Wei3,4, Mingyou Chen3,4, Jiang Liao2, Lufeng Luo3,4,*

    CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2025.064489

    Abstract Defect detection based on computer vision is a critical component in ensuring the quality of industrial products. However, existing detection methods encounter several challenges in practical applications, including the scarcity of labeled samples, limited adaptability of pre-trained models, and the data heterogeneity in distributed environments. To address these issues, this research proposes an unsupervised defect detection method, FLAME (Federated Learning with Adaptive Multi-Model Embeddings). The method comprises three stages: (1) Feature learning stage: this work proposes FADE (Feature-Adaptive Domain-Specific Embeddings), a framework employs Gaussian noise injection to simulate defective patterns and implements a feature discriminator… More >

  • Open Access

    ARTICLE

    ONTDAS: An Optimized Noise-Based Traffic Data Augmentation System for Generalizability Improvement of Traffic Classifiers

    Rongwei Yu1, Jie Yin1,*, Jingyi Xiang1, Qiyun Shao2, Lina Wang1

    CMC-Computers, Materials & Continua, DOI:10.32604/cmc.2025.064438

    Abstract With the emergence of new attack techniques, traffic classifiers usually fail to maintain the expected performance in real-world network environments. In order to have sufficient generalizability to deal with unknown malicious samples, they require a large number of new samples for retraining. Considering the cost of data collection and labeling, data augmentation is an ideal solution. We propose an optimized noise-based traffic data augmentation system, ONTDAS. The system uses a gradient-based searching algorithm and an improved Bayesian optimizer to obtain optimized noise. The noise is injected into the original samples for data augmentation. Then, an More >

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