Wei Chen^*, Wuwen Liu, Yue Liang

FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.029310

Abstract River sand is an essential component used as a fine aggregate in mortar and concrete. Due to unrestrained exploitation, river sand resources are gradually being exhausted. This requires alternative solutions. This study deals with the properties of cement mortar containing different levels of manufactured sand (MS) based on quartzite, used to replace river sand. The river sand was replaced at 20%, 40%, 60% and 80% with MS (by weight or volume). The mechanical properties, transfer properties, and microstructure were examined and compared to a control group to study the impact of the replacement level. The results indicate that the compressive… More >

Hao Zhang¹, Yan Zhang^1,*, Wei Liu², Ximin Zhang³, Xiang Liu²

Energy Engineering, Vol., , DOI:10.32604/ee.2023.041410

Abstract The microscopic characteristics and mechanical properties of rocks change after the action of acid on deep shale, which affects the fracturing effect. Accordingly, we designed and conducted indoor experiments related to the changes in macro and microscopic characteristics after the interaction of acid with the shale of Wujiaping Formation, based on which the characteristic law of fracture volume modification after acid fracturing was studied using numerical simulation. The results demonstrate that the pores and fractures are enlarged and the structure is significantly loosened after the acid immersion. And a 15% concentration of hydrochloric acid can effectively dissolve shale. Furthermore, the… More >

Zediao Chen, Feng Liu^*

CMES-Computer Modeling in Engineering & Sciences, Vol., , DOI:10.32604/cmes.2023.046618

Abstract Crack propagation in brittle material is not only crucial for structural safety evaluation, but also has a wideranging impact on material design, damage assessment, resource extraction, and scientific research. A thorough investigation into the behavior of crack propagation contributes to a better understanding and control of the properties of brittle materials, thereby enhancing the reliability and safety of both materials and structures. As an implicit discrete element method, the Discontinuous Deformation Analysis (DDA) has gained significant attention for its developments and applications in recent years. Among these developments, the particle DDA equipped with the bonded particle model is a powerful… More >

Raghunathan Krishankumar¹, Dhruva Sundararajan², K. S. Ravichandran², Edmundas Kazimieras Zavadskas^3,*

CMES-Computer Modeling in Engineering & Sciences, Vol., , DOI:10.32604/cmes.2023.029438

Abstract Hydrogen is the new age alternative energy source to combat energy demand and climate change. Storage of hydrogen is vital for a nation’s growth. Works of literature provide different methods for storing the produced hydrogen, and the rational selection of a viable method is crucial for promoting sustainability and green practices. Typically, hydrogen storage is associated with diverse sustainable and circular economy (SCE) criteria. As a result, the authors consider the situation a multi-criteria decision-making (MCDM) problem. Studies infer that previous models for hydrogen storage method (HSM) selection (i) do not consider preferences in the natural language form; (ii) weights… More >

XIANGDONG SUN^1,2,#, HUIJUAN WEN^1,2,#, FAZHAN LI^1,2, IHTISHAM BUKHARI^1,2, FEIFEI REN^1,2, XIA XUE^1,2, PENGYUAN ZHENG^1,2,*, YANG MI^1,2,*

Oncology Research, Vol., , DOI:10.32604/or.2023.044618

Abstract Nicotinamide adenine dinucleotide (NAD+) plays an essential role in cellular metabolism, mitochondrial homeostasis, inflammation, and senescence. However, the role of NAD+-regulated genes, including coding and long non-coding genes in cancer development is poorly understood. We constructed a prediction model based on the expression level of NAD+ metabolism-related genes (NMRGs). Furthermore, we validated the expression of NMRGs in gastric cancer (GC) tissues and cell lines; additionally, β-nicotinamide mononucleotide (NMN), a precursor of NAD+, was used to treat the GC cell lines to analyze its effects on the expression level of NMRGs lncRNAs and cellular proliferation, cell cycle, apoptosis, and senescence-associated secretory… More > Graphic Abstract

TINGTING LI¹, WEI ZHONG¹, LIU YANG¹, ZHIYU ZHAO¹, LI WANG¹, CONG LIU¹, WANYUN LI¹, HAIYAN LV², SHENGYU WANG¹, JIANGHUA YAN¹, TING WU^1,*, GANG SONG^1,*, FANGHONG LUO^1,*

Oncology Research, Vol., , DOI:10.32604/or.2023.043807

Abstract The high mortality rate associated with gastric cancer (GC) has resulted in an urgent need to identify novel therapeutic targets for GC. This study aimed to investigate whether GAIP interacting protein, C terminus 1 (GIPC1) represents a therapeutic target and its regulating mechanism in GC. GIPC1 expression was elevated in GC tissues, liver metastasis tissues, and lymph node metastases. GIPC1 knockdown or GIPC1 blocking peptide blocked the platelet-derived growth factor receptor (PDGFR)/PI3K/AKT signaling pathway, and inhibited the proliferation and migration of GC cells. Conversely, GIPC1 overexpression markedly activated the PDGFR/PI3K/AKT signaling pathway, and promoted GC cell proliferation and migration. Furthermore,… More > Graphic Abstract

Ming Liu¹, Pinghua Zhu^2,*, Xiancui Yan², Haichao Li², Xintong Chen²

Journal of Renewable Materials, Vol., , DOI:10.32604/jrm.2023.045381

Abstract As socioeconomic development continues, the issue of building energy consumption has attracted significant attention, and improving the thermal insulation performance of buildings has become a crucial strategic measure. Simultaneously, the application of solid waste in insulation materials has also become a hot topic. This paper reviews the sources and classifications of solid waste, focusing on research progress in its application as insulation materials in the domains of daily life, agriculture, and industry. The research shows that incorporating household solid waste materials, such as waste glass, paper, and clothing scraps into cementitious thermal insulation can significantly reduce the thermal conductivity of… More >

Liting Jia¹, Xiao Han¹, Cuixia Qiao², Gang Zhao², Yanzhi Xia¹, Zhixin Xue^1,*

Journal of Renewable Materials, Vol., , DOI:10.32604/jrm.2023.044310

Abstract Ba²⁺ pre-crosslinked carrageenan fiber (Ba/CAF) was prepared by adding a small amount of Ba²⁺ to the carrageenan (CA) solution as the spinning solution. Ba/CAF-n/A, Ba/CAF-n/B and Ba/CAF-n/C were prepared with ethanol solution (combine A), high concentration BaCl₂ solution (combine B) and low concentration BaCl₂ solution (combine C), as coagulation bath and stretch bath, respectively. The combination of coagulation bath and stretch bath suitable for Ba²⁺ pre-crosslinking wet spinning was screened. The results showed that Ba²⁺ can induce the birefringence of the CA molecular chain, and the Ba²⁺ pre-crosslinking effect is the best when the CA mass fraction is 8.0 wt%.… More > Graphic Abstract

Eun Kyoung Han, Hae Kyoung Son^*

International Journal of Mental Health Promotion, Vol., , DOI:10.32604/ijmhp.2023.041560

Abstract Dementia prevalence has soared due to population aging. In Mild Cognitive Impairment (MCI) as a pre-dementia stage, sleep disturbances have raised much interest as a factor in a bidirectional relationship with cognitive decline. Thus, this study developed the Sleep and Cognition Enhancement Multimodal Intervention (SCEMI) based on Lazarus’ multimodal approach and conducted a randomized controlled experiment to investigate the effects of the novel program on sleep and cognition in MCI elderly. The participants were 55 MCI elderly with sleep disturbances at two dementia care centers located in S-city, Gyeonggi-do, South Korea (n = 25 in the experimental group and n… More >

Chenlin Zhu¹, Yan Zhao¹, Zhitao Jiang¹, Jiafeng Xie³, Lifang Zeng^2,*, Lijuan Qian^1,*

Frontiers in Heat and Mass Transfer, Vol., , DOI:10.32604/fhmt.2023.044433

Abstract Efficient and secure refueling within the vehicle refueling systems exhibits a close correlation with the issues concerning fuel backflow and gasoline evaporation. This paper investigates the transient flow behavior in fuel hose refilling and simplified tank fuel replenishment using the volume of fluid method. The numerical simulation is validated with the simplified hose refilling experiment and the evaporation simulation of Stefan tube. The effects of injection flow rate and injection directions have been discussed in the fuel hose refilling part. For both the experiment and simulation, the pressure at the end of the refueling pipe in the lower located nozzle… More >