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The Fabrication of Water-Soluble Chitosan Capsule Shell Modified by Alginate and Gembili Starch (Dioscorea esculenta L)

Yatim Lailun Ni’mah*, Suprapto Suprapto, Harmami, Ita Ulfin, Puput Asmaul Fauziyah
Chemistry Department, Faculty of Science and Analytical Data, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia
* Corresponding Author: Yatim Lailun Ni’mah. Email:
(This article belongs to this Special Issue: Bio-based/Degradable Materials towards A Sustainable Future)

Journal of Renewable Materials 2022, 10(9), 2365-2376. https://doi.org/10.32604/jrm.2022.020001

Received 28 October 2021; Accepted 07 January 2022; Issue published 30 May 2022

Abstract

Capsule shells have been successfully fabricated from water-soluble chitosan (WSC) with the addition of alginate and Gembili starch. WSC was synthesized from crab shell chitosan by depolymerization reaction. The capsule shells were made with the composition of WSC: Alginate, 2:1, 3:1 and 4:1 (w/w) with and without the addition of Gembili starch. Gembili starch was added with a ratio of Alginate: Starch, 1:1 (w/w). The capsule shell properties were evaluated according to Indonesian Pharmacopoeia standard. The solubility test showed that the capsule shells were comply with the standard. The highest degrees of swelling in water and HCl 0.1 N solution were 491.93% and 410.51%, respectively. The highest degradation percentages in water and HCl 0.1 N solution were 57.80% and 21.44%, respectively. The observation of physical appearance indicated that the capsule shell with WSC: Alginate: Starch in ratio of 3:1:1 has appearance close to commercial capsule shell.

Graphical Abstract

The Fabrication of Water-Soluble Chitosan Capsule Shell Modified by Alginate and Gembili Starch (<i>Dioscorea esculenta</i> L)

Keywords

Capsule shell; water soluble chitosan; capsule shell degradation; capsule shell solubility

Cite This Article

Ni’mah, Y. L., Suprapto, S., , H., Ulfin, I., Fauziyah, P. A. (2022). The Fabrication of Water-Soluble Chitosan Capsule Shell Modified by Alginate and Gembili Starch (Dioscorea esculenta L). Journal of Renewable Materials, 10(9), 2365–2376.



This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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