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  • Open Access

    ARTICLE

    Loss to Specialized Cardiology Follow-Up in Adults Living with Congenital Heart Disease

    Cheryl Dickson1,2,4, Danielle Osborn1, David Baker1,4, Judith Fethney3, David S. Celermajer1,4, Rachael Cordina1,4,*

    Congenital Heart Disease, Vol.19, No.1, pp. 49-63, 2024, DOI:10.32604/chd.2023.044874

    Abstract Background: Much has been written about the loss to follow-up in the transition between pediatric and adult Congenital Heart Disease (CHD) care centers. Much less is understood about the loss to follow-up (LTF) after a successful transition. This is critical too, as patients lost to specialised care are more likely to experience morbidity and premature mortality. Aims: To understand the prevalence and reasons for loss to follow-up (LTF) at a large Australian Adult Congenital Heart Disease (ACHD) centre. Methods: Patients with moderate or highly complex CHD and gaps in care of >3 years (defined as LTF) were identified from a… More >

  • Open Access

    ARTICLE

    Developing risk models and subtypes of autophagy-associated LncRNAs for enhanced prognostic prediction and precision in therapeutic approaches for liver cancer patients

    LU ZHANG*, JINGUO CHU*, YUSHAN YU

    Oncology Research, Vol.32, No.4, pp. 703-716, 2024, DOI:10.32604/or.2023.030988

    Abstract Background: Limited research has been conducted on the influence of autophagy-associated long non-coding RNAs (ARLncRNAs) on the prognosis of hepatocellular carcinoma (HCC). Methods: We analyzed 371 HCC samples from TCGA, identifying expression networks of ARLncRNAs using autophagy-related genes. Screening for prognostically relevant ARLncRNAs involved univariate Cox regression, Lasso regression, and multivariate Cox regression. A Nomogram was further employed to assess the reliability of Riskscore, calculated from the signatures of screened ARLncRNAs, in predicting outcomes. Additionally, we compared drug sensitivities in patient groups with differing risk levels and investigated potential biological pathways through enrichment analysis, using consensus clustering to identify subgroups… More >

  • Open Access

    ARTICLE

    ADVANCES IN THERMODIFFUSION AND THERMOPHORESIS (SORET EFFECT) IN LIQUID MIXTURES

    Morteza Eslamian*

    Frontiers in Heat and Mass Transfer, Vol.2, No.4, pp. 1-20, 2011, DOI:10.5098/hmt.v2.4.3001

    Abstract Recent advances in thermodiffusion (Soret effect) in binary and higher multicomponent liquid mixtures are reviewed. The mixtures studied include the hydrocarbon, associating, molten metal and semiconductor, polymer, and DNA mixtures. The emphasis is placed on the theoretical works, particularly models based on the nonequilibrium thermodynamics, although other approaches such as the statistical, kinetic and hydrodynamic approaches are discussed as well. For each mixture, the major theoretical and experimental works are discussed and the research trends and challenges are addressed. Some of the challenges include a need for combining various methods to develop a comprehensive theoretical model or at least to… More >

  • Open Access

    REVIEW

    The heterogeneity of tumor-associated macrophages and strategies to target it

    HAO LV1, BO ZHU1,2, DEGAO CHEN1,2,*

    BIOCELL, Vol.48, No.3, pp. 363-378, 2024, DOI:10.32604/biocell.2023.046367

    Abstract Tumor-associated macrophages (TAMs) are emerging as targets for tumor therapy because of their primary role in promoting tumor progression. Several studies have been conducted to target TAMs by reducing their infiltration, depleting their numbers, and reversing their phenotypes to suppress tumor progression, leading to the development of drugs in preclinical and clinical trials. However, the heterogeneous characteristics of TAMs, including their ontogenetic and functional heterogeneity, limit their targeting. Therefore, in-depth exploration of the heterogeneity of TAMs, combined with immune checkpoint therapy or other therapeutic modalities could improve the efficiency of tumor treatment. This review focuses on the heterogeneous ontogeny and… More >

  • Open Access

    ARTICLE

    An Artificial Intelligence-Based Framework for Fruits Disease Recognition Using Deep Learning

    Irfan Haider1, Muhammad Attique Khan1,*, Muhammad Nazir1, Taerang Kim2, Jae-Hyuk Cha2

    Computer Systems Science and Engineering, Vol.48, No.2, pp. 529-554, 2024, DOI:10.32604/csse.2023.042080

    Abstract Fruit infections have an impact on both the yield and the quality of the crop. As a result, an automated recognition system for fruit leaf diseases is important. In artificial intelligence (AI) applications, especially in agriculture, deep learning shows promising disease detection and classification results. The recent AI-based techniques have a few challenges for fruit disease recognition, such as low-resolution images, small datasets for learning models, and irrelevant feature extraction. This work proposed a new fruit leaf leaf leaf disease recognition framework using deep learning features and improved pathfinder optimization. Three fruit types have been employed in this work for… More >

  • Open Access

    ARTICLE

    Security Monitoring and Management for the Network Services in the Orchestration of SDN-NFV Environment Using Machine Learning Techniques

    Nasser Alshammari1, Shumaila Shahzadi2, Saad Awadh Alanazi1,*, Shahid Naseem3, Muhammad Anwar3, Madallah Alruwaili4, Muhammad Rizwan Abid5, Omar Alruwaili4, Ahmed Alsayat1, Fahad Ahmad6,7

    Computer Systems Science and Engineering, Vol.48, No.2, pp. 363-394, 2024, DOI:10.32604/csse.2023.040721

    Abstract Software Defined Network (SDN) and Network Function Virtualization (NFV) technology promote several benefits to network operators, including reduced maintenance costs, increased network operational performance, simplified network lifecycle, and policies management. Network vulnerabilities try to modify services provided by Network Function Virtualization MANagement and Orchestration (NFV MANO), and malicious attacks in different scenarios disrupt the NFV Orchestrator (NFVO) and Virtualized Infrastructure Manager (VIM) lifecycle management related to network services or individual Virtualized Network Function (VNF). This paper proposes an anomaly detection mechanism that monitors threats in NFV MANO and manages promptly and adaptively to implement and handle security functions in order… More >

  • Open Access

    EDITORIAL

    Special issue on “Boiling in Microchannels”

    Frontiers in Heat and Mass Transfer, Vol.3, No.1, pp. 1-3, 2012, DOI:10.5098/hmt.v3.1.1001

    Abstract This article has no abstract. More >

  • Open Access

    EDITORIAL

    Introduction to the Special Issue on Recent Developments on Computational Biology-I

    Carlo Cattani1, Haci Mehmet Baskonus2,*, Armando Ciancio3

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 2261-2264, 2024, DOI:10.32604/cmes.2024.050209

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    PCA-LSTM: An Impulsive Ground-Shaking Identification Method Based on Combined Deep Learning

    Yizhao Wang*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3029-3045, 2024, DOI:10.32604/cmes.2024.046270

    Abstract Near-fault impulsive ground-shaking is highly destructive to engineering structures, so its accurate identification ground-shaking is a top priority in the engineering field. However, due to the lack of a comprehensive consideration of the ground-shaking characteristics in traditional methods, the generalization and accuracy of the identification process are low. To address these problems, an impulsive ground-shaking identification method combined with deep learning named PCA-LSTM is proposed. Firstly, ground-shaking characteristics were analyzed and ground-shaking the data was annotated using Baker’s method. Secondly, the Principal Component Analysis (PCA) method was used to extract the most relevant features related to impulsive ground-shaking. Thirdly, a… More >

  • Open Access

    ARTICLE

    Discrete Element Modelling of Damage Evolution of Concrete Considering Meso-Structure of ITZ

    Weiliang Gao1, Shixu Jia2, Tingting Zhao2,3,*, Zhiyong Wang2

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3495-3511, 2024, DOI:10.32604/cmes.2023.046188

    Abstract The mechanical properties of interfacial transition zones (ITZs) have traditionally been simplified by reducing the stiffness of cement in previous simulation methods. A novel approach based on the discrete element method (DEM) has been developed for modeling concrete. This new approach efficiently simulates the meso-structure of ITZs, accurately capturing their heterogeneous properties. Validation against established uniaxial compression experiments confirms the precision of this model. The proposed model can model the process of damage evolution containing cracks initiation, propagation and penetration. Under increasing loads, cracks within ITZs progressively accumulate, culminating in macroscopic fractures that traverse the mortar matrix, forming the complex,… More >

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