Yongxia He¹, Zheng Wang¹, Yue Wang², Man Sun^3,*

Oncologie, Vol.23, No.3, pp. 351-357, 2021, DOI:10.32604/Oncologie.2021.014772

Abstract Gastric cancer is a highly malignant disease with complex pathogenic mechanisms, and has high incidence and mortality rate. At present, the diagnosis of gastric cancer mainly includes gastroscopy, serum analysis and needle biopsy, and the treatment methods include conventional surgical resection, radiotherapy and chemotherapy. Yet, some limitations were involved in these diagnostic and therapeutic methods, so accurate targeted therapy has received considerable attention. MicroRNAs (miRNAs) are non-coding RNA that can interact with the 3-terminal non-translational region of the target gene mRNA to reduce the expression of the target gene, participate in the regulation of multiple signaling pathways, and play an… More >

Hanan A. Hosni Mahmoud, Amal H. Alharbi, Norah S. Alghamdi^*

Intelligent Automation & Soft Computing, Vol.31, No.2, pp. 1273-1286, 2022, DOI:10.32604/iasc.2022.020662

Abstract In this paper we propose a computerized breast cancer detection and breast masses classification system utilizing mammograms. The motivation of the proposed method is to detect breast cancer tumors in early stages with more accuracy and less negative false cases. Our proposed method utilizes clustering of different features by segmenting the breast mammogram and then extracts deep features using the presented Convolution Neural Network (CNN). The extracted features are then combined with subjective features such as shape, texture and density. The combined features are then utilized by the Extreme Learning Machine Clustering (ELMC) algorithm to combine segments together to identify… More >

Ashit Kumar Dutta^*

Intelligent Automation & Soft Computing, Vol.31, No.2, pp. 1007-1023, 2022, DOI:10.32604/iasc.2022.019778

Abstract In recent days, Internet of Things (IoT) based image classification technique in the healthcare services is becoming a familiar concept that supports the process of detecting cancers with Computer Tomography (CT) images. Lung cancer is one of the perilous diseases that increases the mortality rate exponentially. IoT based image classifiers have the ability to detect cancer at an early stage and increases the life span of a patient. It supports oncologist to monitor and evaluate the health condition of a patient. Also, it can decipher cancer risk marker and act upon them. The process of feature extraction and selection from… More >

N. Jayanthi^1,*, D. Manohari², Mohamed Yacin Sikkandar³, Mohamed Abdelkader Aboamer³, Mohamed Ibrahim Waly³, C. Bharatiraja⁴

Intelligent Automation & Soft Computing, Vol.31, No.2, pp. 1317-1329, 2022, DOI:10.32604/iasc.2022.018974

Abstract Lung cancer is a curable disease if detected early, and its mortality rate decreases with forwarding treatment measures. At first, an easy and accurate way to detect is by using image processing techniques on the cancer-affected images captured from the patients. This paper proposes a novel lung cancer detection method. Firstly, an adaptive median filter algorithm (AMF) is applied to preprocess those images for improving the quality of the affected area. Then, a supervised image edge detection algorithm (SIED) is presented to segment those images. Then, feature extraction is employed to extract the mean, standard deviation, energy, contrast, etc., of… More >

G. Jayandhi^1,*, J.S. Leena Jasmine², S. Mary Joans²

Computer Systems Science and Engineering, Vol.40, No.2, pp. 491-503, 2022, DOI:10.32604/csse.2022.016376

Abstract The most common form of cancer for women is breast cancer. Recent advances in medical imaging technologies increase the use of digital mammograms to diagnose breast cancer. Thus, an automated computerized system with high accuracy is needed. In this study, an efficient Deep Learning Architecture (DLA) with a Support Vector Machine (SVM) is designed for breast cancer diagnosis. It combines the ideas from DLA with SVM. The state-of-the-art Visual Geometric Group (VGG) architecture with 16 layers is employed in this study as it uses the small size of 3 × 3 convolution filters that reduces system complexity. The softmax layer… More >

R. Sujitha^*, B. Paramasivan

CMC-Computers, Materials & Continua, Vol.70, No.1, pp. 1557-1572, 2022, DOI:10.32604/cmc.2022.019323

Abstract With the modernization of machine learning techniques in healthcare, different innovations including support vector machine (SVM) have predominantly played a major role in classifying lung cancer, predicting coronavirus disease 2019, and other diseases. In particular, our algorithm focuses on integrated datasets as compared with other existing works. In this study, parallel-based SVM (P-SVM) and multiclass-based multiple submodels (MMSM-SVM) were used to analyze the optimal classification of lung diseases. This analysis aimed to find the optimal classification of lung diseases with id and stages, such as key-value pairs in MapReduce combined with P-SVM and MMSVM for binary and multiclasses, respectively. For… More >

Ali Raza¹, Muhammad Rafiq², Dalal Alrowaili³, Nauman Ahmed⁴, Ilyas Khan^5,*, Kottakkaran Sooppy Nisar⁶, Muhammad Mohsin⁷

CMC-Computers, Materials & Continua, Vol.70, No.1, pp. 1649-1666, 2022, DOI:10.32604/cmc.2022.019148

Abstract Nonlinear modelling has a significant role in different disciplines of sciences such as behavioral, social, physical and biological sciences. The structural properties are also needed for such types of disciplines, as dynamical consistency, positivity and boundedness are the major requirements of the models in these fields. One more thing, this type of nonlinear model has no explicit solutions. For the sake of comparison its computation will be done by using different computational techniques. Regrettably, the aforementioned structural properties have not been restored in the existing computational techniques in literature. Therefore, the construction of structural preserving computational techniques are needed. The… More >

Naglaa F. Soliman^1,2, Naglaa S. Ali², Mahmoud I. Aly^2,3, Abeer D. Algarni^1,*, Walid El-Shafai⁴, Fathi E. Abd El-Samie^1,4

CMC-Computers, Materials & Continua, Vol.70, No.1, pp. 1315-1334, 2022, DOI:10.32604/cmc.2022.017001

Abstract Breast cancer is the most common type of cancer, and it is the reason for cancer death toll in women in recent years. Early diagnosis is essential to handle breast cancer patients for treatment at the right time. Screening with mammography is the preferred examination for breast cancer, as it is available worldwide and inexpensive. Computer-Aided Detection (CAD) systems are used to analyze medical images to detect breast cancer, early. The death rate of cancer patients has decreased by detecting tumors early and having appropriate treatment after operations. Processing of mammogram images has four main steps: pre-processing, segmentation of the… More >

Chandrasekar Thaventhiran, K. R. Sekar^*

Intelligent Automation & Soft Computing, Vol.31, No.1, pp. 495-506, 2022, DOI:10.32604/iasc.2022.019546

Abstract Prediction of lung cancer at early stages is essential for diagnosing and prescribing the correct treatment. With the continuous development of medical data in healthcare services, Lung cancer prediction is the most concerning area of interest. Therefore, early prediction of cancer helps in reducing the mortality rate of humans. The existing techniques are time-consuming and have very low accuracy. The proposed work introduces a novel technique called Target Projection Feature Matched Deep Artificial Neural Network with LSTM (TPFMDANN-LSTM) for accurate lung cancer prediction with minimum time consumption. The proposed deep learning model consists of multiple layers to learn the given… More >

KEWEI GAO^1,#, JIANGFENG HU^2,#, YI ZHOU³, LIANG ZHU^1,*

BIOCELL, Vol.45, No.6, pp. 1521-1526, 2021, DOI:10.32604/biocell.2021.09220

Abstract Increasing evidence proves that circular RNAs (circRNAs) play an important role in regulating the biological behaviors of tumors. The central purpose of this research was to investigate the functions of circRNA in gastric cancer. The utilization of real-time PCR was to test circPTN expression in gastric cancer cells. Cell counting colony formation assays, CCK-8 assay, and EdU assay were used to investigate proliferation. Transwell assay was applied to investigate migration. We discovered that circPTN was highly expressed in gastric cancer cells. Low expression of circPTN inhibits gastric cancer cell proliferation and migration. Elevated expression of circPTN promotes gastric cancer cell… More >