Fatma Nese Efil¹, Sania Qureshi^1,2,3, Nezihal Gokbulut^1,4, Kamyar Hosseini^1,3, Evren Hincal^1,4,*, Amanullah Soomro²

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 485-512, 2024, DOI:10.32604/cmes.2024.047907

Abstract The global population has been and will continue to be severely impacted by the COVID-19 epidemic. The primary objective of this research is to demonstrate the future impact of COVID-19 on those who suffer from other fatal conditions such as cancer, heart disease, and diabetes. Here, using ordinary differential equations (ODEs), two mathematical models are developed to explain the association between COVID-19 and cancer and between COVID-19 and diabetes and heart disease. After that, we highlight the stability assessments that can be applied to these models. Sensitivity analysis is used to examine how changes in certain factors impact different aspects… More >

JIA SHAO^1,2, CAN ZHANG², YAONAN TANG², AIQIN HE², WEIPEI ZHU^1,*

BIOCELL, Vol.48, No.4, pp. 571-580, 2024, DOI:10.32604/biocell.2024.049092

Abstract Objective: Previous studies indicated that aberrant circular RNA (circRNA) expression affects gene expression regulatory networks, leading to the aberrant activation of tumor pathways and promoting tumor cell growth. However, the expression, clinical significance, and effects on cell propagation, invasion, and dissemination of circRNA_001896 in cervical cancer (CC) tissues remain unclear. Methods: The Gene Expression Omnibus (GEO) datasets (GSE113696 and GSE102686) were used to examine differential circRNA expression in CC and adjacent tissues. The expression of circRNA_001896 was detected in 72 CC patients using fluorescence quantitative PCR. Correlation analysis with clinical pathological features was performed through COX multivariate and univariate analysis.… More >

LIJUAN ZHANG^1,#, QINGYIN MENG^2,#, LI ZHUANG¹, QUAN GONG¹, XIANDA HUANG³, XUEQIN LI¹, SHIJUAN LI¹, GUOQIN WANG⁴, XICAI WANG^5,*

BIOCELL, Vol.48, No.4, pp. 581-590, 2024, DOI:10.32604/biocell.2024.047260

Abstract Background: Lung adenocarcinoma is a very pervasive histological form of lung cancers, and inhibiting metastasis is crucial for effective treatment. In this investigation, we explored the functional interaction of miR-30a-5p and the putative transcription factor 2 of the homeodomain (PHTF2) in dictating the aggressiveness and metastasis of lung adenocarcinoma. Method: We collected clinical samples to evaluate the expression patterns of miR-30a-5p and PHTF2 in lung adenocarcinoma along with normal tissues. Cellular experiments including cell count kit (CCK)-8 growth assay, apoptosis analysis, migration and invasion examinations were performed to assess the aggressiveness of lung adenocarcinoma cells. Furthermore, we examined tumorigenesis and… More > Graphic Abstract

JIYU WANG^1,2, HUIXIA LI^1,2, DEYUAN ZHOU^1,2, LIHONG BAI^1,2, KEJING TANG^1,2,3,*

BIOCELL, Vol.48, No.4, pp. 623-637, 2024, DOI:10.32604/biocell.2024.030420

Abstract Background: For patients with lung cancer, timely identification of new lung lesions as infectious or non-infectious, and accurate identification of pathogens is very important in improving OS of patients. As a new auxiliary examination, metagenomic next-generation sequencing (mNGS) is believed to be more accurate in diagnosing infectious diseases in patients without underlying diseases, compared with conventional microbial tests (CMTs). We designed this study to find out whether mNGS has better performance in distinguishing infectious and non-infectious diseases in lung cancer patients using bronchoalveolar lavage fluid (BALF). Materials and Methods: This study was a real-world retrospective review based on electronic medical… More >

PRABHAT KUMAR, ANJANA SARKAR, PURNIMA JAIN^*

Journal of Polymer Materials, Vol.39, No.1-2, pp. 121-135, 2022, DOI:10.32381/JPM.2022.39.1-2.8

Abstract Biocompatible graphene derivative materials (GBMs) to harness the maximum potential of pristine graphene biologically, is the most important strategy for its advanced applications in pharmaceutical and other biomedical fields. Currently, scientists are trying to find this by using biopolymer nanocomposites or anchored materials. Nevertheless, tuning the bare GBMs towards biocompatibility is a beautiful approach to exploit the fundamental potential of pristine graphene vis-à-vis suppressing the effects of incorporated biopolymers or anchored materials. Herein, a large-scale, cost-effective, facile, and environment-friendly green synthetic strategy is used for the synthesis of reduced graphene oxide (rGO) nanosheet using L-ascorbic acid (L-AA) as a reducing/stabilizing/capping… More >

Guilhem Paillard-Brunet^*, Audrey Couillet

Psycho-Oncologie, Vol.18, No.1, pp. 23-31, 2024, DOI:10.32604/po.2023.047888

Abstract This study aimed to gather healthcare professionals’ expectations and reluctance toward peer support in a cancer center. Semistructured interviews were conducted among 12 professionals, recruited in different professions. The interviews were fully transcribed, and a thematic analysis was then conducted. Of the data analysis, three main themes about professionals’ expectations emerged: the need for the strongest support of the patients, to break the isolation in the sickness, and to enhance the care system. Three main themes also emerged from the data analysis about professionals’ reluctances: the limitations related to the intervention of the peer-workers, the psychological issues of the relationship,… More >

Carolle Annie Njopvoui^*, Armel Valdin Teague Tsopgny, Henri Rodrigue Njengoue Ngamaleu

Psycho-Oncologie, Vol.18, No.1, pp. 59-68, 2024, DOI:10.32604/po.2023.047499

Abstract Estimated at more than 2.2 million cases worldwide, most breast cancer cases and deaths from breast cancer occur in low and middle-income countries. In Cameroon, many studies have underlined the effect of knowledge of breast cancer on screening measures such as self-examination and, to a lesser extent, the perception of the threat of this disease. This research aims to assess according to the Health Belief Model (HBM), the moderating effect of perceived threat of breast cancer on the relation between knowledge and breast self-examination. A questionnaire survey was conducted among 517 Cameroonian women to assess their general knowledge about breast… More >

Wanxiu Zhu^*

Psycho-Oncologie, Vol.18, No.1, pp. 69-77, 2024, DOI:10.32604/po.2023.046593

Abstract Exploring the relationship between social support and the mental health of cancer patients is a vital endeavor for enhancing mental well-being. The objective of this study was to explore the relationship between social support and psychological well-being in cancer patients and to provide new empirical evidence for psychological improvement in cancer patients. This research holds significant practical implications for optimizing China’s public health system and strengthening the development of a healthy China. Using data from the 2018 China Health and Retirement Longitudinal Study (CHARLS) database, we empirically examined the influence of social support on the mental health of cancer patients.… More >

Maria Inês Clara^1,2,3,*, Maria Cristina Canavarro^2,3, Ana Severina⁴, Susana Ramos⁴, Carla Rafael⁴, Ana Allen Gomes^1,2,3

Psycho-Oncologie, Vol.18, No.1, pp. 49-57, 2024, DOI:10.32604/po.2023.044320

Abstract Aims: We aimed to compare cancer survivors’ fatigue expression with that of the general population and examine psychobiological factors associated with fatigue. Procedure: In this quantitative, transversal study, we analyzed clinical and sociodemographic indicators of 389 participants (68.38% females): 148 cancer survivors on active treatment, 55 disease-free survivors, 75 patients with another chronic disease, and 111 healthy individuals. Results: Fatigue was expressed dissimilarly in patients with a previous history of cancer and participants without a history of cancer. Survivors on active treatment reported significantly higher levels of fatigue than the other clinical status groups. Nonetheless, some level of cancer-related fatigue… More >

Julien Biaudet^1,*, Lisa Laroussi-Libeault², Mauricette Michallet³, Laurie Panse², Raymond Merle⁴

Psycho-Oncologie, Vol.18, No.1, pp. 17-22, 2024, DOI:10.32604/po.2023.043536

Abstract This article aims to share an innovative experience of organizing and funding research involving those most directly affected: patients. The “ECLAIR” working group of the Canceropole Lyon Auvergne-Rhone-Alpes (CLARA) was created at the end of 2020 with the goal of contributing to the development of a call for projects on the patient experience in oncology, which was launched in January 2021. Initially composed of 8 members, including 7 patients, coordinated by a project manager from CLARA, the ECLAIR working group actively participated in drafting the specifications of the call for projects, developing the eligibility criteria for applications, revising the evaluation… More >