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  • Open Access

    CASE REPORT

    Life Threatening Broad QRS Tachycardia in an Infant with Conduction Disorder and SCN5A Mutation

    Elio Caruso1,*, Silvia Farruggio1, Alfredo Di Pino1, Paolo Guccione1, Mohammadrafie Khorgami2

    Congenital Heart Disease, Vol.17, No.5, pp. 551-556, 2022, DOI:10.32604/chd.2022.023711

    Abstract We present the case of an infant admitted to our department for a rapid broad complex tachycardia and cardiovascular collapse. The patient was submitted to genetic testing because of a conduction defect at baseline ECG and family history of gene mutation. A new SCN5A gene mutation variant was found leading to diagnosis of sodium-channel dysfunction arrhythmia. More > Graphic Abstract

    Life Threatening Broad QRS Tachycardia in an Infant with Conduction Disorder and <i>SCN5A</i> Mutation

  • Open Access

    ARTICLE

    Efficacy of Singing Bowls in Childhood Asthma—A Pilot and Feasibility Study

    Sukhbir Shahid*

    Sound & Vibration, Vol.56, No.3, pp. 245-253, 2022, DOI:10.32604/sv.2022.016139

    Abstract The potential use of sound and vibration for diagnostic and therapeutic purposes remains largely under-explored and under-estimated. Sound and vibrational energy has great positive impact on the mind and body. It could be particularly useful for psychosomatic diseases as a complementary therapy. Singing bowls, the spiritual ancient therapy has been claimed to aid in mind relaxation and painful and inflammatory conditions. Childhood asthma is an inflammatory airway disease and a psychosomatic disorder. The psychological management in it is often neglected leading to under-treatment or a relapse. Hence, we hypothesized that sound therapy with singing bowls might be useful as complementary… More >

  • Open Access

    ARTICLE

    A New Childhood Pneumonia Diagnosis Method Based on Fine-Grained Convolutional Neural Network

    Yang Zhang1, Liru Qiu2, Yongkai Zhu1, Long Wen1,*, Xiaoping Luo2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.133, No.3, pp. 873-894, 2022, DOI:10.32604/cmes.2022.022322

    Abstract Pneumonia is part of the main diseases causing the death of children. It is generally diagnosed through chest X-ray images. With the development of Deep Learning (DL), the diagnosis of pneumonia based on DL has received extensive attention. However, due to the small difference between pneumonia and normal images, the performance of DL methods could be improved. This research proposes a new fine-grained Convolutional Neural Network (CNN) for children’s pneumonia diagnosis (FG-CPD). Firstly, the fine-grained CNN classification which can handle the slight difference in images is investigated. To obtain the raw images from the real-world chest X-ray data, the YOLOv4… More >

  • Open Access

    ARTICLE

    Congenital Coronary Artery Fistula in Children: A Review of 28 Cases with Clinical and Imaging Outcomes

    Pornrawee Plearntummakun1, Chodchanok Vijarnsorn1,*, Kritvikrom Durongpisitkul1, Prakul Chanthong1, Paweena Chungsomprasong1, Supaluck Kanjanauthai1, Thita Pacharapakornpong1, Jarupim Soongswang1, Thaworn Subtaweesin2

    Congenital Heart Disease, Vol.17, No.4, pp. 463-478, 2022, DOI:10.32604/chd.2022.021545

    Abstract Background: Congenital coronary artery fistula (CCAF) is a rare anomaly. Treatment strategies tend to close the defect with a symptomatic and significant shunt, primarily based on expert consensus and case series. Results for long-term follow-up in children are limited Methods: We conducted a retrospective study to assess clinical and imaging outcomes of children with CCAF at Siriraj Hospital, Thailand during 2000–2020. Patients with single ventricle were excluded. Treatment strategies [surgical closure (SC), and percutaneous closure (PC)] were classified and the clinical outcomes at the follow-up in 2021, including coronary thrombosis, myocardial ischemia, and the results of cardiovascular imaging were reviewed.… More > Graphic Abstract

    Congenital Coronary Artery Fistula in Children: A Review of 28 Cases with Clinical and Imaging Outcomes

  • Open Access

    ARTICLE

    Efficacy, Safety and Characteristics of the Amplatzer Vascular Plug II and IV Utilization for Various Percutaneous Occlusions in Children under 10 Years

    Hugues Lucron1,*, Alban-Elouen Baruteau2,3, Caroline Ovaert4, Ali Houeijeh5, Mélanie Brard1, Patrice Guerin2, François Bourlon6, Claire Dauphin7, Saskia Tuttle1, Maha Tagorti3, Rishika Banydeen8, François Godart5

    Congenital Heart Disease, Vol.17, No.4, pp. 421-436, 2022, DOI:10.32604/chd.2022.020835

    Abstract Objectives: We aim to describe the efficacy, safety, and characteristics of the Amplatzer Vascular Plug (AVP) II and IV “off-label” use for multiple cardiovascular occlusions in children under 10 years. Methods: Observational retrospective multicenter (2007–2020, 6 centers) review of paediatric procedures using AVP II or IV. Results: A total of 125 children (49.6% aged ≤ 1 year, 147 lesions) underwent 136 successive procedures (success rate: 98.5%) using 169 devices (109 AVP IV, 60 AVP II). The mean device diameter was 7.7 ± 3.2 mm (4–20 mm). The median AVP size to vessel diameter ratio was 1.3 (0–2). The median age and weight… More > Graphic Abstract

    Efficacy, Safety and Characteristics of the Amplatzer Vascular Plug II and IV Utilization for Various Percutaneous Occlusions in Children under 10 Years

  • Open Access

    ARTICLE

    Excellent Early Outcomes of Combined Chemotherapy With Arsenic Trioxide for Stage 4/M Neuroblastoma in Children: A Multicenter Nonrandomized Controlled Trial

    Chunmou Li*1, Xiaomin Peng*1, Chuchu Feng*1, Xilin Xiong*, Jianxin Li, Ning Liao, Zhen Yang§, Aiguo Liu, Pingping Wu*, Xuehong Liang, Yunyan He, Xin Tian§, Yunbi Lin§, Songmi Wang, Yang Li*

    Oncology Research, Vol.28, No.7-8, pp. 791-800, 2020, DOI:10.3727/096504021X16184815905096

    Abstract This nonrandomized, multicenter cohort, open-label clinical trial evaluated the efficacy and safety of combined chemotherapy with arsenic trioxide (ATO) in children with stage 4/M neuroblastoma (NB). We enrolled patients who were newly diagnosed with NB and assessed as stage 4/M and received either traditional chemotherapy or ATO combined with chemotherapy according to their own wishes. Twenty-two patients were enrolled in the trial group (ATO combined with chemotherapy), and 13 patients were enrolled in the control group (traditional chemotherapy). Objective response rate (ORR) at 4 weeks after completing induction chemotherapy was defined as the main outcome, and adverse events were monitored… More >

  • Open Access

    ARTICLE

    Emotion Exploration in Autistic Children as an Early Biomarker through R-CNN

    S. P. Abirami1,*, G. Kousalya1, R. Karthick2

    Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 595-607, 2023, DOI:10.32604/iasc.2023.027562

    Abstract Autism Spectrum Disorder (ASD) is found to be a major concern among various occupational therapists. The foremost challenge of this neurodevelopmental disorder lies in the fact of analyzing and exploring various symptoms of the children at their early stage of development. Such early identification could prop up the therapists and clinicians to provide proper assistive support to make the children lead an independent life. Facial expressions and emotions perceived by the children could contribute to such early intervention of autism. In this regard, the paper implements in identifying basic facial expression and exploring their emotions upon a time-variant factor. The… More >

  • Open Access

    ARTICLE

    Pathways to Psychiatry Care among Children with Mental Health Problems

    Hisham A. Ramy, Soheir H. Elghonemy, Nesreen M. Mohsen, Safi M. Nagib*, Mohamed Y. Mohamed

    International Journal of Mental Health Promotion, Vol.24, No.4, pp. 539-550, 2022, DOI:10.32604/ijmhp.2022.020108

    Abstract Many children with mental health problems in Egypt, as in many other countries, do not receive the help they need. Investigating the pathways of care is crucial for the early detection and treatment of these children. This study examined referral patterns and the duration of untreated psychiatric illness of 350 children attending two urban clinical settings in Egypt. Diagnoses were made using the Kiddie Schedule for Affective Disorder and Schizophrenia for School-aged children present and lifetime (K-SADS-PL), Child behavior checklist (CBCL,) and the Stanford-Binet Intelligence Scale. For 46.3%, the most distressing symptom was behavioral problems. A delay in seeking psychiatric… More >

  • Open Access

    ARTICLE

    The Effects of Therapeutic Horseback Riding Program on Motor Skills in Children with Autism Spectrum Disorder

    Mengxian Zhao1, Yonghao You2, Jinming Li3, Sean Healy4, Alyx Taylor5, Zhihao Zhang3, Linlin Li6, Liye Zou7,*

    International Journal of Mental Health Promotion, Vol.24, No.4, pp. 475-489, 2022, DOI:10.32604/ijmhp.2022.021361

    Abstract Therapeutic horseback riding (THR) as an animal-assisted intervention is one of the innovative approaches emerging in the treatment for children with autism spectrum disorder (ASD). The current study was designed to investigate the effects of a 12-week, twice a week THR program on motor skills in sixty-eight children with ASD aged 5–10 years old. All participants selected met the DSM-V criteria for ASD, and a total of fifty-three participants completed the study. A randomized controlled trial design was utilized for the study. Data was collected via a pre-THR test, interim-THR test, and post-THR test to investigate the possible changes in… More >

  • Open Access

    ARTICLE

    Predictors of Health-Related Quality of Life in Children with Cyanotic Heart Disease Who Underwent Palliative and Total Repair

    Jutarat Tanasansuttiporn1, Maliwan Oofuvong1,*, Wirat Wasinwong1, Voravit Chittithavorn2, Pongsanae Duangpakdee2, Jirayut Jarutach3, Qistina Yunuswangsa1

    Congenital Heart Disease, Vol.17, No.3, pp. 245-267, 2022, DOI:10.32604/chd.2022.021778

    Abstract Background: Studies on predictors of health-related quality of life (HRQOL) in pediatric patients with cyanotic heart disease who are waiting for the next stage and those who have undergone total repair are scarce. Therefore, we aimed to identify such predictors in children who received the modified Blalock–Taussig shunt (MBTS) and those who underwent total repair. Methods: In this historical cohort and concurrent follow-up study, data of children who underwent MBTS at the age of 0–3 years between January 2005 and December 2016 at a super-tertiary care hospital in Southern Thailand were obtained. Children who were alive in December 2017 were… More > Graphic Abstract

    Predictors of Health-Related Quality of Life in Children with Cyanotic Heart Disease Who Underwent Palliative and Total Repair

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