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  • Open Access

    ARTICLE

    AI-driven radiogenomic analysis of clear cell renal cell carcinoma: perinephric adipose tissue stranding as a key feature of the NIPAL4-associated imaging pattern

    Federico Greco1,2,*, Marco Cataldo3, Valerio D’Andrea2,4, Luca Pugliese5, Andrea Panunzio6, Alessandro Tafuri6, Bruno Beomonte Zobel2,4, Carlo Augusto Mallio2,4

    Canadian Journal of Urology, Vol.32, No.5, pp. 433-443, 2025, DOI:10.32604/cju.2025.068390 - 30 October 2025

    Abstract Background: Radiogenomics offers a non-invasive approach to correlate imaging features with tumor molecular profiles. This study aims to identify computed tomography (CT) imaging characteristics associated with positive NIPA-like domain containing 4 (NIPAL4) expression in clear cell renal cell carcinoma (ccRCC) and to develop a radiogenomic predictive model to support personalized risk stratification. Methods: A retrospective analysis was conducted on 241 ccRCC patients from The Cancer Genome Atlas (TCGA) and The Cancer Imaging Archive (TCIA) databases. Clinical, pathological, and CT features were compared between NIPAL4-positive and NIPAL4-negative groups. A penalized logistic regression model was built to… More >

  • Open Access

    ARTICLE

    RPMS-DSAUnet: A Segmentation Model for the Pancreas in Abdominal CT Images

    Tiren Huang, Chong Luo, Xu Li*

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5847-5865, 2025, DOI:10.32604/cmc.2025.067986 - 23 October 2025

    Abstract Automatic pancreas segmentation in CT scans is crucial for various medical applications including early disease detection, treatment planning and therapeutic evaluation. However, the pancreas’s small size, irregular morphology, and low contrast with surrounding tissues make accurate pancreas segmentation still a challenging task. To address these challenges, we propose a novel RPMS-DSAUnet for accurate automatic pancreas segmentation in abdominal CT images. First, a Residual Pyramid Squeeze Attention module enabling hierarchical multi-resolution feature extraction with dynamic feature weighting and selective feature reinforcement capabilities is integrated into the backbone network, enhancing pancreatic feature extraction and improving localization accuracy.… More >

  • Open Access

    ARTICLE

    DeblurTomo: Self-Supervised Computed Tomography Reconstruction from Blurry Images

    Qingyang Zhou1, Guofeng Lu2, Yunfan Ye3,*, Zhiping Cai1

    CMC-Computers, Materials & Continua, Vol.84, No.2, pp. 2411-2427, 2025, DOI:10.32604/cmc.2025.066810 - 03 July 2025

    Abstract Computed Tomography (CT) reconstruction is essential in medical imaging and other engineering fields. However, blurring of the projection during CT imaging can lead to artifacts in the reconstructed images. Projection blur combines factors such as larger ray sources, scattering and imaging system vibration. To address the problem, we propose DeblurTomo, a novel self-supervised learning-based deblurring and reconstruction algorithm that efficiently reconstructs sharp CT images from blurry input without needing external data and blur measurement. Specifically, we constructed a coordinate-based implicit neural representation reconstruction network, which can map the coordinates to the attenuation coefficient in the… More >

  • Open Access

    ARTICLE

    Optimizing Computed Tomography Processing Parameters for Accurate Detection of Internal Defects in Reinforced Concrete

    Yueshun Chen1,2,*, Yupeng Zhou1, Cao Yin3

    Structural Durability & Health Monitoring, Vol.19, No.3, pp. 575-592, 2025, DOI:10.32604/sdhm.2024.057005 - 03 April 2025

    Abstract Computed tomography (CT) can inspect the internal structure of concrete with high resolution, but improving the accuracy of measurements remains a key challenge due to the reliance on complex image processing and significant manual intervention. This study aims to optimize CT scanning parameters to enhance the accuracy of measuring crack widths and rebar volumes in reinforced concrete. Nine sets of specimens, each with varying rebar diameters and concrete cover thicknesses, were scanned before and after corrosion using an Optima CT scanner, followed by three-dimensional reconstructions using Avizo software. The effects of threshold values and “Erosion” More >

  • Open Access

    ARTICLE

    3D Reconstruction for Early Detection of Liver Cancer

    Rana Mohamed1,2,*, Mostafa Elgendy1, Mohamed Taha1

    Computer Systems Science and Engineering, Vol.49, pp. 213-238, 2025, DOI:10.32604/csse.2024.059491 - 10 January 2025

    Abstract Globally, liver cancer ranks as the sixth most frequent malignancy cancer. The importance of early detection is undeniable, as liver cancer is the fifth most common disease in men and the ninth most common cancer in women. Recent advances in imaging, biomarker discovery, and genetic profiling have greatly enhanced the ability to diagnose liver cancer. Early identification is vital since liver cancer is often asymptomatic, making diagnosis difficult. Imaging techniques such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT), and ultrasonography can be used to identify liver cancer once a sample of liver tissue is… More >

  • Open Access

    PROCEEDINGS

    Effects of Hatch Spacing on Pore Segregation and Mechanical Properties During Blue Laser Directed Energy Deposition of AlSi10Mg

    Hongze Wang1,2,3,*, An Wang1,2, Zijue Tang1,2, Yi Wu1,2,3, Haowei Wang1,2,3,4

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012430

    Abstract Hatch spacing is a crucial parameter for achieving superior mechanical properties during the process of laser directed energy deposition (L-DED) process. However, the optimum hatch spacing is based on trial and error approaches using pre-existing experience. In this paper, we have systematically compared the porosity characteristics, microstructure evolution, and thermal gradients in double tracks of AlSi10Mg under various hatch spacings during blue laser directed energy deposition (BL-DED). A peculiar phenomenon of pore segregation is observed at the boundary of the overlapping zone of adjacent deposited tracks, where the porosity is almost 8 times that of… More >

  • Open Access

    REVIEW

    A Survey of Lung Nodules Detection and Classification from CT Scan Images

    Salman Ahmed1, Fazli Subhan2,3, Mazliham Mohd Su’ud3,*, Muhammad Mansoor Alam3,4, Adil Waheed5

    Computer Systems Science and Engineering, Vol.48, No.6, pp. 1483-1511, 2024, DOI:10.32604/csse.2024.053997 - 22 November 2024

    Abstract In the contemporary era, the death rate is increasing due to lung cancer. However, technology is continuously enhancing the quality of well-being. To improve the survival rate, radiologists rely on Computed Tomography (CT) scans for early detection and diagnosis of lung nodules. This paper presented a detailed, systematic review of several identification and categorization techniques for lung nodules. The analysis of the report explored the challenges, advancements, and future opinions in computer-aided diagnosis CAD systems for detecting and classifying lung nodules employing the deep learning (DL) algorithm. The findings also highlighted the usefulness of DL… More >

  • Open Access

    PROCEEDINGS

    Characterization on Fracture Toughness of Cermet Coating Coupling Instrumented Indentation and X-Ray Computed Tomography

    Ruizhe Huang1, Zhaoliang Qu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.011440

    Abstract The surface brittle fracture of cermet coating seriously restricts its application. Accurate evaluation of the fracture toughness of cermet coating is a prerequisite for improving its life. This paper aims to propose an accurate characterization method for fracture toughness of cermet coating. By coupling instrumented indentation and X‑ ray computed tomography, the indentation-induced fracture behaviors under various loads within WC-12%Co coatings were studied. The indentation response was correlated with the damage evolution directly observed within the coating. The impact of substrate effects on indentation-induced fracture behaviors was further studied using finite element analysis (FEA). The… More >

  • Open Access

    ARTICLE

    Enhancing Multi-Modality Medical Imaging: A Novel Approach with Laplacian Filter + Discrete Fourier Transform Pre-Processing and Stationary Wavelet Transform Fusion

    Mian Muhammad Danyal1,2, Sarwar Shah Khan3,4,*, Rahim Shah Khan5, Saifullah Jan2, Naeem ur Rahman6

    Journal of Intelligent Medicine and Healthcare, Vol.2, pp. 35-53, 2024, DOI:10.32604/jimh.2024.051340 - 08 July 2024

    Abstract Multi-modality medical images are essential in healthcare as they provide valuable insights for disease diagnosis and treatment. To harness the complementary data provided by various modalities, these images are amalgamated to create a single, more informative image. This fusion process enhances the overall quality and comprehensiveness of the medical imagery, aiding healthcare professionals in making accurate diagnoses and informed treatment decisions. In this study, we propose a new hybrid pre-processing approach, Laplacian Filter + Discrete Fourier Transform (LF+DFT), to enhance medical images before fusion. The LF+DFT approach highlights key details, captures small information, and sharpens… More >

  • Open Access

    ARTICLE

    Material-SAM: Adapting SAM for Material XCT

    Xuelong Wu1, Junsheng Wang1,*, Zhongyao Li1, Yisheng Miao1, Chengpeng Xue1, Yuling Lang2, Decai Kong2, Xiaoying Ma2, Haibao Qiao2

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3703-3720, 2024, DOI:10.32604/cmc.2024.047027 - 26 March 2024

    Abstract X-ray Computed Tomography (XCT) enables non-destructive acquisition of the internal structure of materials, and image segmentation plays a crucial role in analyzing material XCT images. This paper proposes an image segmentation method based on the Segment Anything model (SAM). We constructed a dataset of carbide in nickel-based single crystal superalloys XCT images and preprocessed the images using median filtering, histogram equalization, and gamma correction. Subsequently, SAM was fine-tuned to adapt to the task of material XCT image segmentation, resulting in Material-SAM. We compared the performance of threshold segmentation, SAM, U-Net model, and Material-SAM. Our method More >

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