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  • Open Access

    ARTICLE

    Sex ratio and spatial distribution of pistillate and staminate plants of Dasylirion cedrosanum

    Reyes-Valdés MH, JD Hernández-Quintero1, YA Morales-Reyes2, DV Mendoza-Rodríguez, DU González-Uribe, F Ramírez-Godina, JA Villarreal-Quintanilla

    Phyton-International Journal of Experimental Botany, Vol.86, pp. 171-180, 2017, DOI:10.32604/phyton.2017.86.171

    Abstract The genus Dasylirion forms a group of well-represented perennial, dioecious species called “sotoles” in Mexico. This genus is a main component of the arid lands of northern Mexico and southern United States, and plays important ecological and economic roles. Four D. cedrosanum populations from northeastern Mexico were surveyed to gather statistics related to sex ratios and spatial distribution. The statistics were performed on an unbiased sample of 448 plants. Tests for sex ratio and spatial distribution were carried out. No evidence of departure from a 1:1 sex ratio proportion was found, both at the global level and More >

  • Open Access

    ARTICLE

    Suppression of Ubiquitin-Specific Peptidase 17 (USP17) Inhibits Tumorigenesis and Invasion in Non-Small Cell Lung Cancer Cells

    Shengchao Zhang, Jun Yuan, Ruheng Zheng

    Oncology Research, Vol.24, No.4, pp. 263-269, 2016, DOI:10.3727/096504016X14666990347392

    Abstract Recently, deubiquitinating enzymes (DUBs) are emerging as new regulators in cancer progression. However, understanding of the involvement of DUBs in non-small cell lung cancer (NSCLC) is just beginning. In this study, we investigated the expression and biological function of ubiquitin-specific peptidase 17 (USP17) in NSCLC progression in vitro and in vivo. We found that the expression of USP17 was higher than in a normal control. We further efficiently depleted USP17 expression in two different NSCLC cells, A549 and H1299. The anchorage-independent growth ability of these cells, estimated by soft agar colony formation assay, was significantly More >

  • Open Access

    ARTICLE

    Selenium invoked antioxidant defense system in Azolla caroliniana plant

    Hassan AMA, EM Mostafa

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 262-269, 2016, DOI:10.32604/phyton.2016.85.262

    Abstract Plants of Azolla caroliniana were treated with different selenium concentrations (0, 1, 2, 5, 7, 10 ppm) for seven days. Selenium (Se) content in Azolla plants increased significantly with increasing Se concentrations in the culture media up to 5 ppm. This indicated that Azolla plants were a good accumulator for Se. Selenium accumulation determined changes in Azolla biomass, doubling time and relative growth rates. Treatment of Azolla plants with low concentrations of Se (1 ppm) resulted in a significant increase in biomass. This was accompanied by a reduction in hydrogen peroxide and malondialdehyde (MDA) contents; the decrease percentages… More >

  • Open Access

    ARTICLE

    Optimized enzyme-assisted microwave extraction and potential inhibitory action against α-glucosidase of polysaccharides from sweet corncobs

    Ma YQ, X Wang, SH Gao, J Zhang

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 79-86, 2016, DOI:10.32604/phyton.2016.85.079

    Abstract The conditions for extracting polysaccharides from sweet corncobs (SCP) were studied. Four parameters (ratio of water to raw material, compound enzyme concentration, temperature of enzymolysis and duration of enzymolysis) affecting the extraction of SCP were optimized using response surface methodology (RSM). Under the optimized conditions, the yield of SCP was 17.58 %. SCP had inhibitory effects on α-amylase and α-glucosidase activities, and the IC50 was 20.91 mg/mL and 12.47 mg/mL. SCP may therefore have prevention and treatment effects on postprandial hyperglycemia in diabetes. The inhibitory effects of SCP were improved after fractionation, and were strongest in More >

  • Open Access

    REVIEW

    What Is the Optimal Dose and Schedule for Dasatinib in Chronic Myeloid Leukemia: Two Case Reports and Review of the Literature

    Caroline Jamison*, Debra Nelson, Mete Eren, Dron Gauchan, Ryan Ramaekers, Max Norvell, Mehmet Sitki Copur

    Oncology Research, Vol.23, No.1-2, pp. 1-5, 2015, DOI:10.3727/096504015X14452563485986

    Abstract Efficacy and safety of dasatinib in chronic phase (CP) chronic myelogenous leukemia (CML) patients has been well established. Initially approved dose and schedule of 70 mg twice daily has been changed to 100 mg once daily after demonstration of the same efficacy with less toxicity. Some patients require significant dose reductions to enable continued treatment with dasatinib. Even at a dose of 80 mg once daily, several patients may require further dose reductions due to substantial toxicity while maintaining good control of their disease. We report two CP-CML patients achieving and maintaining major molecular responses More >

  • Open Access

    ARTICLE

    Seed morphology, presence of areoles and water entry at imbibition of Vicia dasycarpa Ten. cv. Tolse F.C.A

    Perissé P1 y GM Tourn2

    Phyton-International Journal of Experimental Botany, Vol.84, No.1, pp. 184-189, 2015, DOI:10.32604/phyton.2015.84.184

    Abstract The morphological characteristics of the seeds of Vicia dasycarpa Ten. cv. Tolse FCA were studied in relation to the area of imbibition water entry and were considered the presence of areoles. Seeds were analyzed using a stereo, optical and scanning electron microscope (SEM). The determination of the initial water entry area was carried out by immersing the seeds in a solution of tetrazolium (1%). This study showed that this species has seeds with a halo framing the hilum, an inconspicuous dry aril and a deltoid micropyle. The seedcoat pattern is papillose. The tracheid bar is surrounded More >

  • Open Access

    ARTICLE

    Study of the mitotic and meiotic chromosomes of sotol (Dasylirion cedrosanum Trel.)

    Hernández-Quintero JD1, MH Reyes-Valdés2, DV Mendoza-Rodríguez3, M Gómez-Martínez2, R Rodríguez-Herrera4

    Phyton-International Journal of Experimental Botany, Vol.84, No.1, pp. 107-112, 2015, DOI:10.32604/phyton.2015.84.107

    Abstract The genus Dasylirion is a group of plants typically present in the Chihuahuan Desert, perennial, with a dioecious sexual behavior and commonly called sotoles. This genus has been little studied from the biological point of view, and the bases of its reproductive response remain unknown. In this work we studied the chromosome number and meiotic response of Dasylirion cedrosanum in the county of Saltillo, Coahuila, located at the North East of Mexico. For the preparation of mitotic chromosomes, we used a technique based on enzymatic treatment with pectolyase and cellulase, as well as staining with acetocarmin… More >

  • Open Access

    ABSTRACT

  • Open Access

    ABSTRACT

  • Open Access

    ARTICLE

    Antimalarial drug artesunate aff ords protection against carrageenan induced acute infl ammation in rat

    Vijay L. KUMAR1 *, B. GURUPRASAD1, Priyanka CHAUDHARY2

    BIOCELL, Vol.38, No.1, pp. 1-6, 2014, DOI:10.32604/biocell.2014.38.001

    Abstract Artesunate, an antimalarial drug, has been shown to inhibit the release of inflammatory mediators in various disease conditions. The present study was carried out to evaluate the anti-edematogenic effect of artesunate in the rat paw edema model. Inflammation was induced in the hind paw of rat by sub-plantar injection of 0.1 mL of 0.5% carrageenan and the paw volume was measured up to a fixed mark just before the injection and then after 3 h. The difference in two volumes gave a measure of edema formation. At 3h the level of TNF-α, PGE2 and myeloperoxidase More >

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