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  • Open Access

    ARTICLE

    Hybrid Metamodel—NSGA-III—EDAS Based Optimal Design of Thin Film Coatings

    Kamlendra Vikram1, Uvaraja Ragavendran2, Kanak Kalita1,*, Ranjan Kumar Ghadai3, Xiao-Zhi Gao4

    CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1771-1784, 2021, DOI:10.32604/cmc.2020.013946

    Abstract In this work, diamond-like carbon (DLC) thin film coatings are deposited on silicon substrates by using plasma-enhanced chemical vapour deposition (PECVD) technique. By varying the hydrogen (H2) flow rate, CH4−Argon (Ar) flow rate and deposition temperature (Td) as per a Box-Behnken experimental design (BBD), 15 DLC deposition experiments are carried out. The Young’s modulus (E) and the coefficient of friction (COF) for the DLCs are measured. By using a second-order polynomial regression approach, two metamodels are built for E and COF, that establish them as functions of H2 flow rate, CH4-Ar flow rate and Td. A non-dominated sorting genetic algorithm… More >

  • Open Access

    ARTICLE

    Intrusion Detection and Anticipation System (IDAS) for IEEE 802.15.4 Devices

    Usman Tariq

    Intelligent Automation & Soft Computing, Vol.25, No.2, pp. 231-242, 2019, DOI:10.31209/2018.100000040

    Abstract Wireless Sensor Networks (WSNs) empower the reflection of the environment with an extraordinary resolve. These systems are combination of several minuscule squat-cost, and stumpy-power on-chip transceiver sensing motes. Characteristically, a sensing device comprises of four key gears: an identifying element for data attainment, a microcontroller for native data dispensation, a message component to permit the broadcast/response of data to/from additional associated hardware, and lastly, a trivial energy source. Near field frequency series and inadequate bandwidth of transceiver device drags to multi-stage data transactions at minimum achievable requirements. State of art, and prevailing operating systems, such as TinyOS (Levis, et.al. 2005),… More >

  • Open Access

    ARTICLE

    Dithiothreitol and PEG Induced Combined Stress May Affect the Expressions of ABA Aldehyde Oxidase, Sucrose Synthase and Proline Metabolic Genes in Maize Seedlings

    Cansu Altuntaş1, Rabiye Terzi1,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.3, pp. 487-495, 2020, DOI:10.32604/phyton.2020.08919

    Abstract The endoplasmic reticulum (ER) is an organelle in the cell where proteins are created and folded. Folding is a very elaborate process that is often interrupted by various biotic and abiotic stresses, leading to the formation of unfolded and misfolded proteins called ER stress. Dithiothreitol (DTT)-induced unfolded protein response (UPR) in endoplasmic reticulum (ER) has been recently reported in plants. Also, previous studies demonstrated that treatment with polyethylene glycol (PEG6000) could stimulate water deficit in crops. However, further researches should be conducted to elucidate the molecular mechanism of ER stress response and the relationship between water deficiency and ER. In… More >

  • Open Access

    ARTICLE

    Pharmacotherapy for patent ductus arteriosus closure

    John M. Ferguson

    Congenital Heart Disease, Vol.14, No.1, pp. 52-56, 2019, DOI:10.1111/chd.12715

    Abstract Even though up to 60% of premature infants less than 28 weeks gestation develop persistent patent ductus arteriosus (PDA), there remains controversy regarding if, when, and how to close the PDA. Failure to close the PDA has been associated with significant morbidity but no cause‐and‐effect has been proven for short‐term or long‐term outcomes in modern times. Surgical closure has the advantage of eliminating the PDA, but short‐term complications and long‐term adverse outcomes are worrisome. Intravenous indomethacin has been the “gold standard” for pharmacologic treatment over the past 40 years with high closure rates and decreased incidence of severe intraventricular hemorrhage… More >

  • Open Access

    ARTICLE

    Comparative case studies: PDAs treated with medication, surgical ligation, and transcatheter device closure

    Ruth Seaton, Chandler Williams, Julia Peredo

    Congenital Heart Disease, Vol.14, No.1, pp. 65-68, 2019, DOI:10.1111/chd.12711

    Abstract The ductus arteriosus is a lifeline for the developing fetus prior to delivery, allowing the circulation of oxygen‐rich blood from the placenta to bypass the lungs and per‐ fuse the body. However, when the ductus fails to close after birth, the pressures can cause blood to shunt from the aorta back into the lungs, causing pulmonary edema. This is called a left‐to‐right shunt. The patent ductus arteriosus (PDA) can also shunt blood from the pulmonary arteries to the aorta, bypassing the lungs and causing oxy‐ gen‐poor blood to mix with the oxygen‐rich blood circulating to the body. This is called… More >

  • Open Access

    ARTICLE

    An in vitro study to explore the role of prolylcarboxypeptidase in non-small cell lung cancer

    Binbin QIAN1, Xiaoduo LIU2, Xiaolin GU1, Lu YANG3, Dake CHEN1,*

    BIOCELL, Vol.44, No.1, pp. 19-26, 2020, DOI:10.32604/biocell.2020.07859

    Abstract Prolylcarboxypeptidase (PRCP) belongs to the S28 family of proteases, which is also a dipeptidyl peptidase. In this study, we demonstrate the expression pattern of PRCP in Non-small cell lung cancer (NSCLC). We found that the repression of PRCP expression by small interfering RNA successfully inhibited cell proliferation, migration, and invasion. Further, we explored the involvement of PRCP in the regulation of epithelial-mesenchymal transition (EMT). The epithelial marker E-cadherin was significantly increased, meanwhile mesenchymal markers MUC1, vimentin, and SNAIL were markedly decreased in PRCP knockdown cells. Moreover, the downregulation of PRCP in the NSCLC cells induced the expression of apoptosis-related proteins… More >

  • Open Access

    ARTICLE

    Chemical Constituents from Turnip and Their Effects on α-Glucosidase

    Swastika Paul1,3, Xuemei Zhang1, Yongping Yang2, Changan Geng1,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 131-136, 2020, DOI:10.32604/phyton.2020.08328

    Abstract Brassica rapa var. rapa (turnip) is an important crop in Qinghai-Tibet Plateau (QTP) with anti-hypoxic effect. Turnip is rich in glucosinolates, isothiocyanates and phenolic compounds with diverse biological activities, involving anti-oxidant, anti-tumor, anti-diabetic, anti-inflammatory, anti-microbial, hypolipidemic, cardioprotective, hepatoprotective, nephroprotective and analgesic properties. In this study, the ethyl acetate (EtOAc) and butanol parts of Brassica rapa were first revealed with inhibitory effects on α-glucosidase, whereas the water part was inactive. Subsequent bioassay-guided isolation on the EtOAc and butanol parts yielded 12 compounds, involving three indole derivatives, indole-3- acetonitrile (1) 4-methoxyindole-3-acetonitrile (2) and indole-3-aldehyde (3) two flavonoids, liquiritin (4) and licochalcone A… More >

  • Open Access

    ARTICLE

    Stress Ameliorative Effects of Indole Acetic Acid on Hordeum vulgare L. Seedlings Subjected to Zinc Toxicity

    Monika Sood1, Shanti S. Sharma1, Joginder Singh1, Ram Prasad2,3,*, Dhriti Kapoor1,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 71-86, 2020, DOI:10.32604/phyton.2020.07180

    Abstract The heavy metals present in the environment accumulate in the plants and affect their productivity and yield. By entering the food chain, metals cause several serious health problems in human beings as well as in other organisms. Indole acetic acid (IAA) is known to act as a signaling molecule between symbiotic association of metal accumulating plants and plant growth promoting rhizobacteria (PGPR). Present study demonstrated a protective role of IAA against surplus Zinc (Zn)-induced toxicity to Hordeum vulgare seedlings. Elevated Zn concentrations suppressed the plant growth, caused a reduction in leaf relative water contents (RWC) and elevated free proline and… More >

  • Open Access

    ARTICLE

    Synaptonemal complexes and XY behavior in two species of argentinian armadillos: Chaetophractus villosus and Dasypus hybridus (Xenarthra, Dasypodidae)

    R. B. SCIURANO, M.S. MERANI, JIMENA BUSTOS, A.J. SOLARI

    BIOCELL, Vol.30, No.1, pp. 57-66, 2006, DOI:10.32604/biocell.2006.30.057

    Abstract Spermatocytes from the two armadillo species, C. villosus and D. hybridus were studied in microspreads for synaptonemal complexes (SCs) and in thin sections for electron microscopy (EM). The complete SC karyotype generally agrees with previous reports on mitotic chromosomes, except for the sex chromosomes. The X chromosome is submetacentric in both species and the Y is the shortest one in C. villosus and the second shortest in D. hybridus, and an extremely acrocentric one. A SC is formed along the total length of the Y chromosome, and this SC persists along all the pachytene substages. A single recombination nodule (RN)… More >

  • Open Access

    ARTICLE

    Selenium invoked antioxidant defense system in Azolla caroliniana plant

    Hassan AMA, EM Mostafa

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 262-269, 2016, DOI:10.32604/phyton.2016.85.262

    Abstract Plants of Azolla caroliniana were treated with different selenium concentrations (0, 1, 2, 5, 7, 10 ppm) for seven days. Selenium (Se) content in Azolla plants increased significantly with increasing Se concentrations in the culture media up to 5 ppm. This indicated that Azolla plants were a good accumulator for Se. Selenium accumulation determined changes in Azolla biomass, doubling time and relative growth rates. Treatment of Azolla plants with low concentrations of Se (1 ppm) resulted in a significant increase in biomass. This was accompanied by a reduction in hydrogen peroxide and malondialdehyde (MDA) contents; the decrease percentages were 78%… More >

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