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  • Open Access

    ARTICLE

    A Multi-Constraint Path Optimization Scheme Based on Information Fusion in Software Defined Network

    Jinlin Xu1,2, Wansu Pan1,*, Longle Cheng1,2, Haibo Tan1,2, Munan Yuan1,*, Xiaofeng Li1,2

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1399-1418, 2024, DOI:10.32604/cmc.2024.049622

    Abstract The existing multipath routing in Software Defined Network (SDN) is relatively blind and inefficient, and there is a lack of cooperation between the terminal and network sides, making it difficult to achieve dynamic adaptation of service requirements and network resources. To address these issues, we propose a multi-constraint path optimization scheme based on information fusion in SDN. The proposed scheme collects network topology and network state information on the network side and computes disjoint paths between end hosts. It uses the Fuzzy Analytic Hierarchy Process (FAHP) to calculate the weight coefficients of multiple constrained parameters and constructs a composite quality… More >

  • Open Access

    ARTICLE

    MIDNet: Deblurring Network for Material Microstructure Images

    Jiaxiang Wang1, Zhengyi Li1, Peng Shi1, Hongying Yu2, Dongbai Sun1,3,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1187-1204, 2024, DOI:10.32604/cmc.2024.046929

    Abstract Scanning electron microscopy (SEM) is a crucial tool in the field of materials science, providing valuable insights into the microstructural characteristics of materials. Unfortunately, SEM images often suffer from blurriness caused by improper hardware calibration or imaging automation errors, which present challenges in analyzing and interpreting material characteristics. Consequently, rectifying the blurring of these images assumes paramount significance to enable subsequent analysis. To address this issue, we introduce a Material Images Deblurring Network (MIDNet) built upon the foundation of the Nonlinear Activation Free Network (NAFNet). MIDNet is meticulously tailored to address the blurring in images capturing the microstructure of materials.… More >

  • Open Access

    ARTICLE

    Biological function of miRNA-145-5p in angiotensin II induced renal inflammation

    BIN LI1,2,3,#, YUCHENG SHENG4,#, XIAOYING XU4, SHENGCUN WANG3, HONGYAN SONG3, JINGYUAN LI3, HAONAN JI1, QINGHUA WANG3, XIAODI ZHOU1,*, LONGJU QI2,*

    BIOCELL, Vol.48, No.4, pp. 601-611, 2024, DOI:10.32604/biocell.2024.047404

    Abstract Objective: Chronic kidney disease (CKD) is a progressive disorder characterized by intricate structural and functional alterations in the kidneys, attributable to diverse causative factors. Notably, the therapeutic promise of miR-145-5p in addressing renal pathologies has been discerned. This investigation seeks to elucidate the functional role of miR-145-5p in injured kidneys by subjecting human glomerular mesangial cells (HGMCs) to stimulation with Angiotensin II (AngII). Materials and Methods: Cellular viability and the levels of inflammatory mediators were evaluated utilizing Cell Counting Kit-8 (CCK-8), quantitative real-time polymerase chain reaction (qRT-PCR), and western blot methodologies, both in the presence of AngII incubation and in… More >

  • Open Access

    ARTICLE

    Study of the Effect of Graphite Filler on the Vulcanizing Behavior and Properties of Nitrile Rubber and NBRPVC Blends

    D. MURALI MANOHAR1,*, B.C. CHAKRABORTY2, S. SHAMSHATH BEGUM3

    Journal of Polymer Materials, Vol.37, No.1-2, pp. 91-107, 2020, DOI:10.32381/JPM.2020.37.1-2.7

    Abstract In search of improved materials for efficient shock and vibration mounts for machineries, graphite loaded NBR and NBR/PVC blend were made and investigated. The scorch time was seen to be reduced and vulcanization rate was enhanced due to graphite inclusion. Scanning electron microscopy images have shown homogenous dispersion of graphite powder. NBRgraphite showed a gradual increase in the hardness, tensile strength, Young’s modulus, and tear values with increasing graphite loading. In the case of NBR/PVC-graphite composition, a drop in the tensile strength and increase in the Young’ modulus and tear strength was observed. Various mathematical models were used to investigate… More >

  • Open Access

    ARTICLE

    Identifying and validating MMP family members (MMP2, MMP9, MMP12, and MMP16) as therapeutic targets and biomarkers in kidney renal clear cell carcinoma (KIRC)

    KUNLUN LI1, DANDAN LI2, BARBOD HAFEZ3,*, MOUNIR M. SALEM BEKHIT4, YOUSEF A. BIN JARDAN4, FARS KAED ALANAZI4, EHAB I. TAHA4, SAYED H. AUDA4, FAIQAH RAMZAN5,*, MUHAMMAD JAMIL6

    Oncology Research, Vol.32, No.4, pp. 737-752, 2024, DOI:10.32604/or.2023.042925

    Abstract Kidney Renal Clear Cell Carcinoma (KIRC) is a malignant tumor that carries a substantial risk of morbidity and mortality. The MMP family assumes a crucial role in tumor invasion and metastasis. This study aimed to uncover the mechanistic relevance of the MMP gene family as a therapeutic target and diagnostic biomarker in Kidney Renal Clear Cell Carcinoma (KIRC) through a comprehensive approach encompassing both computational and molecular analyses. STRING, Cytoscape, UALCAN, GEPIA, OncoDB, HPA, cBioPortal, GSEA, TIMER, ENCORI, DrugBank, targeted bisulfite sequencing (bisulfite-seq), conventional PCR, Sanger sequencing, and RT-qPCR based analyses were used in the present study to analyze MMP… More >

  • Open Access

    ARTICLE

    ADVANCES IN THERMODIFFUSION AND THERMOPHORESIS (SORET EFFECT) IN LIQUID MIXTURES

    Morteza Eslamian*

    Frontiers in Heat and Mass Transfer, Vol.2, No.4, pp. 1-20, 2011, DOI:10.5098/hmt.v2.4.3001

    Abstract Recent advances in thermodiffusion (Soret effect) in binary and higher multicomponent liquid mixtures are reviewed. The mixtures studied include the hydrocarbon, associating, molten metal and semiconductor, polymer, and DNA mixtures. The emphasis is placed on the theoretical works, particularly models based on the nonequilibrium thermodynamics, although other approaches such as the statistical, kinetic and hydrodynamic approaches are discussed as well. For each mixture, the major theoretical and experimental works are discussed and the research trends and challenges are addressed. Some of the challenges include a need for combining various methods to develop a comprehensive theoretical model or at least to… More >

  • Open Access

    ARTICLE

    Security Monitoring and Management for the Network Services in the Orchestration of SDN-NFV Environment Using Machine Learning Techniques

    Nasser Alshammari1, Shumaila Shahzadi2, Saad Awadh Alanazi1,*, Shahid Naseem3, Muhammad Anwar3, Madallah Alruwaili4, Muhammad Rizwan Abid5, Omar Alruwaili4, Ahmed Alsayat1, Fahad Ahmad6,7

    Computer Systems Science and Engineering, Vol.48, No.2, pp. 363-394, 2024, DOI:10.32604/csse.2023.040721

    Abstract Software Defined Network (SDN) and Network Function Virtualization (NFV) technology promote several benefits to network operators, including reduced maintenance costs, increased network operational performance, simplified network lifecycle, and policies management. Network vulnerabilities try to modify services provided by Network Function Virtualization MANagement and Orchestration (NFV MANO), and malicious attacks in different scenarios disrupt the NFV Orchestrator (NFVO) and Virtualized Infrastructure Manager (VIM) lifecycle management related to network services or individual Virtualized Network Function (VNF). This paper proposes an anomaly detection mechanism that monitors threats in NFV MANO and manages promptly and adaptively to implement and handle security functions in order… More >

  • Open Access

    ARTICLE

    DeepSVDNet: A Deep Learning-Based Approach for Detecting and Classifying Vision-Threatening Diabetic Retinopathy in Retinal Fundus Images

    Anas Bilal1, Azhar Imran2, Talha Imtiaz Baig3,4, Xiaowen Liu1,*, Haixia Long1, Abdulkareem Alzahrani5, Muhammad Shafiq6

    Computer Systems Science and Engineering, Vol.48, No.2, pp. 511-528, 2024, DOI:10.32604/csse.2023.039672

    Abstract Artificial Intelligence (AI) is being increasingly used for diagnosing Vision-Threatening Diabetic Retinopathy (VTDR), which is a leading cause of visual impairment and blindness worldwide. However, previous automated VTDR detection methods have mainly relied on manual feature extraction and classification, leading to errors. This paper proposes a novel VTDR detection and classification model that combines different models through majority voting. Our proposed methodology involves preprocessing, data augmentation, feature extraction, and classification stages. We use a hybrid convolutional neural network-singular value decomposition (CNN-SVD) model for feature extraction and selection and an improved SVM-RBF with a Decision Tree (DT) and K-Nearest Neighbor (KNN)… More >

  • Open Access

    ARTICLE

    Improving Prediction of Chronic Kidney Disease Using KNN Imputed SMOTE Features and TrioNet Model

    Nazik Alturki1, Abdulaziz Altamimi2, Muhammad Umer3,*, Oumaima Saidani1, Amal Alshardan1, Shtwai Alsubai4, Marwan Omar5, Imran Ashraf6,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3513-3534, 2024, DOI:10.32604/cmes.2023.045868

    Abstract Chronic kidney disease (CKD) is a major health concern today, requiring early and accurate diagnosis. Machine learning has emerged as a powerful tool for disease detection, and medical professionals are increasingly using ML classifier algorithms to identify CKD early. This study explores the application of advanced machine learning techniques on a CKD dataset obtained from the University of California, UC Irvine Machine Learning repository. The research introduces TrioNet, an ensemble model combining extreme gradient boosting, random forest, and extra tree classifier, which excels in providing highly accurate predictions for CKD. Furthermore, K nearest neighbor (KNN) imputer is utilized to deal… More >

  • Open Access

    ARTICLE

    A Sound Quality Evaluation Method for Vehicle Interior Noise Based on Auditory Loudness Model

    Zhiheng He1, Hui Guo2, Houguang Liu1,*, Yu Zhao1,3, Zipeng Zhang1, Shanguo Yang1

    Sound & Vibration, Vol.58, pp. 47-58, 2024, DOI:10.32604/sv.2024.045470

    Abstract When designing and optimizing the hull of vehicles, their sound quality needs to be considered, which greatly depends on the psychoacoustic parameters. However, the traditional psychoacoustic calculation method does not consider the influence of the real human ear anatomic structure, even the loudness which is most related to the auditory periphery. In order to introduce the real physiological structure of the human ear into the evaluation of vehicle sound quality, this paper first carried out the vehicle internal noise test to obtain the experimental samples. Then, the physiological loudness was predicted based on an established human ear physiological model, and… More >

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