Yanqun Dong¹, Karen J. Ruth², Thomas M. Churilla¹, Rosalia Viterbo³, Mark L. Sobczak¹, Marc C. Smaldone³, David Y.T. Chen³, Robert G. Uzzo³, Mark H. Hallman¹, Eric M. Horwitz¹

Canadian Journal of Urology, Vol.24, No.1, pp. 8656-8662, 2017

Abstract Introduction: To evaluate if androgen deprivation therapy (ADT) improves outcomes for patients with localized, intermediate-risk prostate cancer treated with definitive external beam radiation therapy (EBRT) in the dose-escalated era.
Materials and methods: This is a retrospective study using a single institutional database. We included patients with localized, intermediate-risk prostate cancer treated with dose-escalated radiation therapy (RT) with 3D conformal radiotherapy or intensity-modulated radiotherapy (74-80 Gy in daily fraction of 1.8 Gy-2.0 Gy, or 70.2 Gy in daily fraction of 2.7 Gy) from 1992 to 2013. To further risk stratify the patients, PSA 10 ng/mL-20 ng/mL, Gleason 3+4,… More >

Mee-Young Ahn^*1, Hyo-Eun Yoon^†1, Seong-Yong Moon^‡, Yong-Chul Kim^§, Jung-Hoon Yoon^†

Oncology Research, Vol.25, No.2, pp. 295-304, 2017, DOI:10.3727/096504016X14732527645922

Abstract Photodynamic therapy (PDT) is a therapeutic alternative for malignant tumors that uses a photosensitizer. Our group recently synthesized photosensitizer pheophorbide a (Pa) from chlorophyll-a. The present study investigated the therapeutic effect of PDT using intratumoral administration of the synthetic photosensitizer Pa in an in vivo murine oral squamous cell carcinoma (OSCC) animal model. Pa accumulation was measured using the fluorescence spectrum and imaging in living C3H mice. Intratumoral treatment of Pa-PDT (IT Pa-PDT) significantly inhibited the growth of transplanted OSCC cells. Histopathological examination of tumor tissues showed that PCNA expression was significantly decreased, while TUNEL-stained… More >

K. Abe¹, H. Fujii¹, S. Yoshimura¹

CMES-Computer Modeling in Engineering & Sciences, Vol.113, No.1, pp. 71-87, 2017, DOI:10.3970/cmes.2017.113.068

Abstract Microscopic traffic simulations are useful for solving various traffic- related problems, e.g. traffic jams and accidents, local and global environmental and energy problems, maintaining mobility in aging societies, and evacuation plan- ning for natural as well as man-made disasters. The origin-destination (OD) matrix is often used as the input to represent traffic demands into traffic simulators. In this study, we propose an indirect method for estimating the OD matrix using a traffic simulator as an internal model. The proposed method is designed to output results that are consistent with the input of the simulator. The More >

Meryem NAOUM¹, Mustapha EL ALAMI²

FDMP-Fluid Dynamics & Materials Processing, Vol.12, No.2, pp. 56-68, 2016, DOI:10.3970/fdmp.2016.012.056

Abstract A numerical study of mixed convection from a U-shaped channel is carried out. The flow is considered two dimensionnel. The inlet opening is adjusted in the right vertical part of the channel, while the outlet one is placed on the left vertical part. Navier–Stokes equations are solved using a control volume method and the SIMPLEC algorithm is considered for the treatment of pressure–velocity coupling. Special emphasis is given to detail the effect of the Reynolds and Rayleigh numbers on the heat transfer generated by mixed convection. The results are given for the parameters of control More >

ADNANI Massinissa¹, MEZIANI Bachir², OURRAD Ouerdia², ZITOUNE Mounir¹

FDMP-Fluid Dynamics & Materials Processing, Vol.12, No.1, pp. 1-14, 2016, DOI:10.3970/fdmp.2016.012.001

Abstract A numerical study of natural convection in a square cavity subjected to the thermals boundary conditions on the sidewalls is presented and discussed. The fluid is Newtonian and equations governing the flow field and the heat transfer are given in dimensionless form. The finite volume method was adopted to solve the algebraic system. Influence of the Prandtl and the Rayleigh numbers on heat transfer and the flow field is illustrated and discussed as the stream functions, isotherms, horizontal velocity, local and average Nusselt numbers. Results indicate that improved heat transfer is more pronounced with increasing More >

CMC-Computers, Materials & Continua, Vol.52, No.2, pp. 123-131, 2016, DOI:10.3970/cmc.2016.052.123

Abstract In this paper, the gyrotropic bi-anisotropy of the chiral medium in substrate constitutive parameters (xc and hc) of a rectangular microstrip patch antenna is introduced in order to observe its effects on the complex resonant frequency and half-power bandwidth. The analysis is based on the full-wave spectral domain approach using the Moment Method, with sinusoidal type basis functions. The numerical calculations related to the dominant mode have been carried out, and it has been observed that the resonant frequency and the bandwidth are directly linked to the medium chirality. The new results can be considered More >

Zhengzheng Cao¹, Yuejin Zhou^1,2

CMC-Computers, Materials & Continua, Vol.48, No.2, pp. 77-90, 2015, DOI:10.3970/cmc.2015.048.077

Abstract Reasonable width design of narrow coal pillar is the key for ensuring stability of surrounding rock in the roadway driving along next goaf. Based on movement characteristics of overlying strata in gob-side entry, the paper establishes the mechanical model of surrounding rock structure for roadway driving along next goaf, and analyzes the interaction mechanism between key blocks and coal pillar. Besides, in allusion to the mechanical equilibrium of key block B in basic roof, the stability coefficients K₁ and K₂ of key block B and sensitive coefficient of influencing factor are introduced. When the stability coefficient K₁ is… More >

Mohammad Ilati¹, Mehdi Dehghan²

CMES-Computer Modeling in Engineering & Sciences, Vol.109-110, No.4, pp. 325-360, 2015, DOI:10.3970/cmes.2015.109.325

Abstract In this paper, at first, a new combined shape function is proposed. Then, based on this shape function, the meshless local weak form method is applied to find the numerical solution of time-dependent non-linear Brusselator and Gierer- Meinhardt systems. The combined shape function inherits the properties of radial point interpolation (RPI), moving least squares (MLS) and moving Kriging (MK) shape functions and is controlled by control parameters, which take different values in the domain [0;1]. The combined shape function provides synchronic use of different shape functions and this leads to more flexibility in the used More >

Neeraj Dubey¹, Geeta Agnihotri¹

CMC-Computers, Materials & Continua, Vol.45, No.1, pp. 39-56, 2015, DOI:10.3970/cmc.2015.045.039

Abstract In this paper, midrib of coconut palm leaves (MCL) was investigated for the purpose of development of natural fiber reinforced polymer matrix composites. A new natural fiber composite as MCL/polyester is developed by the hand lay-up method, and the material and mechanical properties of the fiber, matrix and composite materials were evaluated. The effect of fiber content on the tensile, flexural, impact, compressive strength and heat distortion temperature (HDT) was investigated. It was found that the MCL fiber had the maximum tensile strength, tensile modulus flexural strength, flexural modulus and Izod impact strength of 177.5MPa, More >

Hawa Singh¹, Paras Ram², Vikas Kumar³

FDMP-Fluid Dynamics & Materials Processing, Vol.10, No.4, pp. 521-550, 2014, DOI:10.3970/fdmp.2014.010.521

Abstract The fluctuating flow produced by magneto - hydrodynamic free convection past an impulsively started isothermal vertical plate is studied taking into account the effects of radiation and viscous dissipation. By using the similarity transformation, the governing equations are transformed into dimensionless form and then the system of nonlinear partial differential equations is solved by a perturbation technique. The considered uniform magnetic field acts perpendicular to the plate, which absorbs the fluid with a given suction velocity. A comparison is made in velocity and temperature profiles for two particular cases of real and imaginary time dependent More >