B. Li¹, F. Li¹, H-X. Li¹, X-C. Xu¹, M. Szczodry¹, Z-C. Yang¹, J-S. Lin², J. H-C. Wang^{1, *}

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 225-227, 2006, DOI:10.32604/mcb.2006.003.225

Abstract This article has no abstract. More >

F. Li¹, X. Wang¹, X. Liao¹, C. Niyibizi¹

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 167-168, 2006, DOI:10.32604/mcb.2006.003.167

Abstract This article has no abstract. More >

E. K. Moioli¹, B. Shah¹, P. A. Clark¹, M. Stroscio¹, J. J. Mao¹

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 153-155, 2006, DOI:10.32604/mcb.2006.003.153

Abstract This article has no abstract. More >

I. A. Titushkin¹, M. Cho¹

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 151-151, 2006, DOI:10.32604/mcb.2006.003.151

Abstract This article has no abstract. More >

Zahra HOSSEININIA¹, Sara SOLTANIAN², Naser MAHDAVI-SHAHRI³, Hesam DEHGHANI^1,4

BIOCELL, Vol.43, No.3, pp. 145-154, 2019, DOI:10.32604/biocell.2019.06468

Abstract Maintenance of pluripotency depends to diverse regulatory factors. Studies in embryonic stem cells (ESCs) have indicated that large intergenic non-coding RNAs (lincRNAs) are involved in the regulatory network of pluripotency. However, the presence and function of pluripotency-associated lincRNAs in cancer cells with pluripotency features are unknown. In this study, we used embryonal carcinoma (EC) P19 cell lines to investigate the expression level of Halr1 in pluripotency and retinoic acid (RA)-induced differentiated states. Down-regulation of pluripotency associated factors such as OCT4, NANOG, SSEA1 and alkaline phosphatase at transcript and protein levels were used to confirm the differentiated status of P19 cells.… More >

James D.Turner, Manoranjan Majji, John L. Junkins

The International Conference on Computational & Experimental Engineering and Sciences, Vol.16, No.1, pp. 11-12, 2011, DOI:10.3970/icces.2011.016.011

Abstract Modeling uncertainty for nonlinear systems is often handled by developing a mathematical model, defining suitable parameters, establishing suitable initial conditions and numerically integrating the system response in order to study the behavior of the system. The potential range of behaviors that can be realized is assessed by varying the model parameters, integrating the response, and recording the changes in the system behaviors. In theory this process is straightforward for implementing. The only potential barrier to carrying out the repeated integrations of the system dynamics is the availability of powerful computer resources that can provide the density of sample points required… More >

Ruikai Chen¹, Delphine Dean^1,*

Molecular & Cellular Biomechanics, Vol.14, No.3, pp. 153-169, 2017, DOI:10.3970/mcb.2017.014.153

Abstract Vascular smooth muscle cells (VSMCs) play an important role in regulating blood flow and pressure by contracting and relaxing in response to a variety of mechanical stimuli. A fully differentiated and functional VSMC should have both the ability to contract and relax in response to environmental stimuli. In addition, it should have the proper mechanical properties to sustain the mechanically active vascular environment. Stem cells can differentiate towards VSMC lineages and so could be used as a potential treatment for vascular repair. However, few studies have assessed the time it takes for stems cells to acquire similar mechanical property to… More >

Yidan Chen^#,1, Kang Zhang^#,1, Juhui Qiu¹, Shicheng He¹, Junyang Huang², Lu Huang¹, Dongyu Jia³, Bo Ling¹, Da Sun⁴, Xiang Xie¹, Tieying Yin^*,1, Guixue Wang^*,1

Molecular & Cellular Biomechanics, Vol.14, No.2, pp. 83-100, 2017, DOI:10.3970/mcb.2017.014.081

Abstract Abnormal shear stress in the blood vessel is an important stimulating factor for the formation of angiogenesis and vulnerable plaques. This paper intended to explore the role of shear stress-regulated Id1 in angiogenesis. First, we applied a carotid artery ring ligation to create local stenosis in ApoE^-/- mice. Then, 3D geometry of the vessel network was reconstructed based on MRI, and our analysis of computational fluid dynamics revealed that wall shear stress of the proximal region was much higher than that of the distal region. In addition, results from histological staining of the proximal region found more vulnerable-probe plaques with… More >

F. S. Tabatabaei^∗, M. Jazayeri^†, P. Ghahari^‡, N. Haghighipour^§

Molecular & Cellular Biomechanics, Vol.11, No.3, pp. 209-220, 2014, DOI:10.3970/mcb.2014.011.209

Abstract During orthodontic treatments, applied mechanical forces create strain and result in tooth movement through the alveolar bone. This response to mechanical strain is a fundamental biological reaction. The present study evaluated the effect of equiaxial strain within the range of orthodontic forces on the osteogenic differentiation of human dental pulp stem cells (hDPSCs). Following isolation and culture of hDPSCs, 3rd passage cells were transferred on a silicone membrane covered with collagen. Cell adhesion to the membrane was evaluated under scanning electron microscope (SEM). Cells were divided into three groups: the first group was placed in a conventional culture medium, transferred… More >

Norizadeh Abbariki Tannaz^*,†, Shokrgozar Mohammad Ali^†,‡, Haghighipour Nooshin^*,§, Aghdami Nasser^¶, Mahdian Rezak^II, Amanzadeh Amir^*, Jazayeri Maryam^*,†

Molecular & Cellular Biomechanics, Vol.11, No.1, pp. 19-37, 2014, DOI:10.3970/mcb.2014.011.019

Abstract Background: Environmental factors affect stem cell differentiation. In addition to chemical factors, mechanical signals have been suggested to enhance myogenic differentiation of stem cells. Therefore, this study was undertaken to illustrate and compare the effect of chemical and mechanical stimuli on Myogenin (MyoG) and Myosin heavy chani 2 (Myh2) expression of mouse bone marrowderived mesenchymal stem cells (BMSCs) and embryonic stem cells (ESCs). Methods: After isolation and expansion of BMSCs and generation of embryoid bodies and spontaneous differentiation of ESCs, cells were examined in 4 groups: (1) control group: untreated cells; (2) chemical group: cells incubated in myogenic medium (5-azacythidine… More >