Umair Muneer Butt^1,2,*, Rimsha Arif², Sukumar Letchmunan^1,*, Babur Hayat Malik², Muhammad Adil Butt²

CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 2551-2570, 2023, DOI:10.32604/cmc.2023.039164

Abstract The detection of brain disease is an essential issue in medical and research areas. Deep learning techniques have shown promising results in detecting and diagnosing brain diseases using magnetic resonance imaging (MRI) images. These techniques involve training neural networks on large datasets of MRI images, allowing the networks to learn patterns and features indicative of different brain diseases. However, several challenges and limitations still need to be addressed further to improve the accuracy and effectiveness of these techniques. This paper implements a Feature Enhanced Stacked Auto Encoder (FESAE) model to detect brain diseases. The standard stack auto encoder’s results are… More >

AN-SOO JANG^*

BIOCELL, Vol.47, No.8, pp. 1703-1708, 2023, DOI:10.32604/biocell.2023.028975

Abstract Exposure to air pollutants such as PM₁₀, PM_2.5, PM_0.1, O₃, CO, NO₂, and SO₂, and biological pollutants are important factors causing the evolution and furtherance of obstructive lung diseases (OLD), including asthma and chronic obstructive pulmonary disease (COPD). Asthma is the most frequent chronic inflammatory airway disease, characterized by breathlessness, wheezing, chest tightness, and cough, together with the presence of exaggerated expiratory airflow fluctuation that varies over time. COPD is a heterogeneous lung condition characterized by chronic respiratory symptoms such as dyspnea, cough, expectoration, and/or exacerbations due to abnormalities of the airways and/or alveoli that cause persistent, often progressive, airflow… More >

CARL RANDALL HARREL¹, VALENTIN DJONOV², ANA VOLAREVIC³, DRAGICA PAVLOVIC⁴, VLADISLAV VOLAREVIC^4,5,*

BIOCELL, Vol.47, No.8, pp. 1757-1769, 2023, DOI:10.32604/biocell.2023.028567

Abstract Exosomes derived from mesenchymal stem cells (MSC-Exos) are nano-sized extracellular vesicles enriched with bioactive molecules, such as microRNAs, enzymes, cytokines, chemokines, immunomodulatory, trophic, and growth factors. These molecules regulate the survival, phenotype, and function of malignant and tumor-infiltrated immune cells. Due to their nano-size and bilayer lipid envelope, MSC-Exos can easily bypass biological barriers and may serve as drug carriers to deliver chemotherapeutics directly into the tumor cells. Here, we summarize current knowledge regarding molecular mechanisms responsible for MSC-Exos-dependent modulation of tumor progression and discuss insights regarding the therapeutic potential of MSC-Exos in the treatment of malignant diseases. More > Graphic Abstract

B. Ramesh, Kuruva Lakshmanna^*

CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.3, pp. 2513-2528, 2023, DOI:10.32604/cmes.2023.028944

Abstract Major chronic diseases such as Cardiovascular Disease (CVD), diabetes, and cancer impose a significant burden on people and healthcare systems around the globe. Recently, Deep Learning (DL) has shown great potential for the development of intelligent mobile Health (mHealth) interventions for chronic diseases that could revolutionize the delivery of health care anytime, anywhere. The aim of this study is to present a systematic review of studies that have used DL based on mHealth data for the diagnosis, prognosis, management, and treatment of major chronic diseases and advance our understanding of the progress made in this rapidly developing field. Type 2… More > Graphic Abstract

Fawad Ali Shah¹, Habib Akbar¹, Abid Ali^2,3, Parveen Amna⁴, Maha Aljohani⁵, Eman A. Aldhahri⁶, Harun Jamil^7,*

Computer Systems Science and Engineering, Vol.47, No.2, pp. 1385-1413, 2023, DOI:10.32604/csse.2023.036144

Abstract The detection of rice leaf disease is significant because, as an agricultural and rice exporter country, Pakistan needs to advance in production and lower the risk of diseases. In this rapid globalization era, information technology has increased. A sensing system is mandatory to detect rice diseases using Artificial Intelligence (AI). It is being adopted in all medical and plant sciences fields to access and measure the accuracy of results and detection while lowering the risk of diseases. Deep Neural Network (DNN) is a novel technique that will help detect disease present on a rice leave because DNN is also considered… More >

Shah Faisal¹, Kashif Javed¹, Sara Ali¹, Areej Alasiry², Mehrez Marzougui², Muhammad Attique Khan^3,*, Jae-Hyuk Cha^4,*

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 895-914, 2023, DOI:10.32604/cmc.2023.039781

Abstract Citrus fruit crops are among the world’s most important agricultural products, but pests and diseases impact their cultivation, resulting in yield and quality losses. Computer vision and machine learning have been widely used to detect and classify plant diseases over the last decade, allowing for early disease detection and improving agricultural production. This paper presented an automatic system for the early detection and classification of citrus plant diseases based on a deep learning (DL) model, which improved accuracy while decreasing computational complexity. The most recent transfer learning-based models were applied to the Citrus Plant Dataset to improve classification accuracy. Using… More >

Ali Haider Khan^1,2,*, Hassaan Malik², Wajeeha Khalil³, Sayyid Kamran Hussain⁴, Tayyaba Anees⁵, Muzammil Hussain²

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 133-150, 2023, DOI:10.32604/cmc.2023.039518

Abstract To prevent irreversible damage to one’s eyesight, ocular diseases (ODs) need to be recognized and treated immediately. Color fundus imaging (CFI) is a screening technology that is both effective and economical. According to CFIs, the early stages of the disease are characterized by a paucity of observable symptoms, which necessitates the prompt creation of automated and robust diagnostic algorithms. The traditional research focuses on image-level diagnostics that attend to the left and right eyes in isolation without making use of pertinent correlation data between the two sets of eyes. In addition, they usually only target one or a few different… More >

Bhawna Goyal^1,*, Ayush Dogra², Rahul Khoond¹, Dawa Chyophel Lepcha¹, Vishal Goyal³, Steven L. Fernandes⁴

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 311-327, 2023, DOI:10.32604/cmc.2023.038398

Abstract The synthesis of visual information from multiple medical imaging inputs to a single fused image without any loss of detail and distortion is known as multimodal medical image fusion. It improves the quality of biomedical images by preserving detailed features to advance the clinical utility of medical imaging meant for the analysis and treatment of medical disorders. This study develops a novel approach to fuse multimodal medical images utilizing anisotropic diffusion (AD) and non-subsampled contourlet transform (NSCT). First, the method employs anisotropic diffusion for decomposing input images to their base and detail layers to coarsely split two features of input… More >

Mona Jamjoom¹, Ahmed Elhadad², Hussein Abulkasim^3,*, Safia Abbas⁴

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 367-382, 2023, DOI:10.32604/cmc.2023.037310

Abstract Several pests feed on leaves, stems, bases, and the entire plant, causing plant illnesses. As a result, it is vital to identify and eliminate the disease before causing any damage to plants. Manually detecting plant disease and treating it is pretty challenging in this period. Image processing is employed to detect plant disease since it requires much effort and an extended processing period. The main goal of this study is to discover the disease that affects the plants by creating an image processing system that can recognize and classify four different forms of plant diseases, including Phytophthora infestans, Fusarium graminearum,… More >

Huaxin Zhou^1,2, Ziying Fang³, Yilin Wang⁴, Mengjun Tong^1,2,*

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 175-194, 2023, DOI:10.32604/cmc.2023.037342

Abstract Plant diseases have become a challenging threat in the agricultural field. Various learning approaches for plant disease detection and classification have been adopted to detect and diagnose these diseases early. However, deep learning entails extensive data for training, and it may be challenging to collect plant datasets. Even though plant datasets can be collected, they may be uneven in quantity. As a result, the problem of classification model overfitting arises. This study targets this issue and proposes an auxiliary classifier GAN (small-ACGAN) model based on a small number of datasets to extend the available data. First, after comparing various attention… More >