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  • Open Access

    ARTICLE

    CYP19A1 Silencing Inhibits Cell Proliferation and Endoplasmic Reticulum Stress in Stomach Adenocarcinoma

    Yi Jin1, Zexing Shan2, Fan Yang1, Xinwen Fan1, Jie Lin3, Zeqing Huang1,*, Xudong Zhu3,4,*

    Oncology Research, Vol.33, No.10, pp. 2937-2960, 2025, DOI:10.32604/or.2025.062250 - 26 September 2025

    Abstract Background: As a major histopathological subtype of gastric cancer (GC), stomach adenocarcinoma (STAD) is an important malignant tumor in the digestive system. Increasing evidence also indicates that endoplasmic reticulum (ER) stress plays a pivotal role in the pathogenesis and progression of GC. Therefore, this study aims to screen and identify vital ER stress-related genes that could contribute to the malignant development and poor prognosis for STAD. Methods: A novel ER stress-related risk score signature was developed employing machine learning techniques. Then, a prognostic prediction nomogram was also built based on the clinicopathological characteristics and the… More > Graphic Abstract

    CYP19A1 Silencing Inhibits Cell Proliferation and Endoplasmic Reticulum Stress in Stomach Adenocarcinoma

  • Open Access

    ARTICLE

    Stress Detection of IT and Hospital Workers Using Novel ResTFTNet and Federated Learning Models

    Pikkili Gopala Krishna1,*, Jalari Somasekar2

    Intelligent Automation & Soft Computing, Vol.40, pp. 235-259, 2025, DOI:10.32604/iasc.2025.063657 - 28 April 2025

    Abstract Stress is mental tension caused by difficult situations, often experienced by hospital workers and IT professionals who work long hours. It is essential to detect the stress in shift workers to improve their health. However, existing models measure stress with physiological signals such as PPG, EDA, and blink data, which could not identify the stress level accurately. Additionally, the works face challenges with limited data, inefficient spatial relationships, security issues with health data, and long-range temporal dependencies. In this paper, we have developed a federated learning-based stress detection system for IT and hospital workers, integrating… More >

  • Open Access

    ARTICLE

    Effect of Proline Pretreatment on the Water Stress Response in “Siete Caldos” Pepper Plants

    Blanca Olivia Trejo-Paniagua1, Nancy Ruiz-Lau2,*, María Goretty Caamal-Chan3, Rosa Isela Cruz-Rodríguez1, Anayancy Lam-Gutiérrez4, Víctor Manuel Ruíz-Valdiviezo1

    Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 861-873, 2025, DOI:10.32604/phyton.2025.062410 - 31 March 2025

    Abstract Exogenous proline is an effective agent for increasing plant tolerance to abiotic stress in plants. In this study, we evaluated its effect on seedlings of Siete Caldos chili pepper (Capsicum frutescens), a semi-domesticated variety. The Capsicum genus is known for its sensitivity to water stress. We pretreated the seedlings’ roots by immersing them in proline solutions (0, 2.5, 5, 7.5, and 10 mM) for 48 h. Then, we exposed them to water stress using a Hoagland nutrient solution supplemented with 10% polyethylene glycol (PEG-8000) for nine days. We analyzed key physiological and biochemical parameters, including relative… More >

  • Open Access

    ARTICLE

    Spatial Variability Assessment on Staple Crop Yields in Hisar District of Haryana, India Using GIS and Remote Sensing

    Sanghati Banerjee1, Om Pal2, Tauseef Ahmad3, Shruti Kanga4, Suraj Kumar Singh1,*, Bhartendu Sajan1

    Revue Internationale de Géomatique, Vol.34, pp. 71-88, 2025, DOI:10.32604/rig.2025.057963 - 24 February 2025

    Abstract Agriculture is a primary activity in many countries, with wheat being a major cereal crop in India. Accurate pre-harvest forecasts of crop acreage and production are critical for policymakers to address supply-demand dynamics, pricing, and trade. This study focuses on estimating wheat acreage and yield in Barwala block, Hisar district, Haryana, for the 2019–2020 Rabi season using remote sensing techniques. Multi-temporal satellite data capturing phenological stages of wheat (Seedling to Ripening) were processed using supervised classification with a maximum likelihood classifier in ERDAS Imagine. Wheat crop acreage was determined by overlaying ground truth points on… More >

  • Open Access

    ARTICLE

    Comparative Effects of Compost and Arbuscular Mycorrhizal Fungi Versus NPK on Agro-Physiological, Biochemical and Tolerance Responses of Tomatoes to Drought

    Abderrahim Boutasknit1,2,3,*, Wissal Benaffari2,3, Mohamed Anli2,3, Abdoussadeq Ouamnina2,3, Amine Assouguem4, Rachid Lahlali4,*, Abdelilah Meddich2,3,5

    Phyton-International Journal of Experimental Botany, Vol.93, No.12, pp. 3589-3616, 2024, DOI:10.32604/phyton.2024.057881 - 31 December 2024

    Abstract Drought stress (DS) and overuse of chemical fertilizers cause considerable losses in the agro-physiological as well as biochemical performance of plants. In this context, considerable effort will be required to replace chemical fertilizers (NPK) with biostimulants as an important approach to enhance the productivity and sustainability of agriculture. Here, we evaluated the effect of separating and/or combining arbuscular mycorrhizal fungi (AMF) with compost (C) in comparison to the use of NPK on the growth, physiological and biochemical of tomatoes under DS. The findings showed that DS significantly reduced the growth and physiological attributes of tomatoes.… More >

  • Open Access

    ARTICLE

    The Hydraulic Fracturing Optimization for Stacked Tight Gas Reservoirs Using Multilayers and Multiwells Fracturing Strategies

    Yuanyuan Yang1, Xian Shi1,2,*, Cheng Ji3, Yujie Yan3, Na An3, Teng Zhang4

    Energy Engineering, Vol.121, No.12, pp. 3667-3688, 2024, DOI:10.32604/ee.2024.056266 - 22 November 2024

    Abstract Based on a geology-engineering sweet spot evaluation, the high-quality reservoir zones and horizontal well landing points were determined. Subsequently, fracture propagation and production were simulated with a multilayer fracturing scenario. The optimal hydraulic fracturing strategy for the multilayer fracturing network was determined by introducing a vertical asymmetry factor. This strategy aimed to minimize stress shadowing effects in the vertical direction while maximizing the stimulated reservoir volume (SRV). The study found that the small vertical layer spacing of high-quality reservoirs and the presence of stress-masking layers (with a stress difference of approximately 3~8 MPa) indicate that… More > Graphic Abstract

    The Hydraulic Fracturing Optimization for Stacked Tight Gas Reservoirs Using Multilayers and Multiwells Fracturing Strategies

  • Open Access

    ARTICLE

    Arbuscular Mycorrhizal Fungi Improve Drought Tolerance of Quinoa Grown in Compost-Amended Soils by Altering Primary and Secondary Metabolite Levels

    Wissal Benaffari1,2,3, Fatima-Ezzahra Soussani1,2,4, Abderrahim Boutasknit1,2,5, Salma Toubali1,2,3, Abir Ben Hassine3, Hala Ben Ahmed3, Rachid Lahlali7,*, Abdelilah Meddich1,2,6,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2285-2302, 2024, DOI:10.32604/phyton.2024.055052 - 30 September 2024

    Abstract Quinoa (Chenopodium quinoa) has recently gained popularity as a pseudo-cereal cultivated in various countries due to the nutritional and antioxidant benefits of its seeds, and its capacity to persist in water-stressed environments. Our study aimed to assess the effects of native arbuscular mycorrhizal fungi (AMF) and local organic amendments on the metabolic responses and antioxidant activity of quinoa seeds under water-stressed conditions. To this end, quinoa plants were grown in soils inoculated with an indigenous mycorrhizal consortium AMF and amended with two types of compost from horse manure (HM) and green waste (GW) under two water… More >

  • Open Access

    ARTICLE

    Enhancing Canola Yield and Photosynthesis under Water Stress with Hydrogel Polymers

    Elham A. Badr1, Gehan Sh. Bakhoum1, Mervat Sh. Sadak2, Ibrahim Al-Ashkar3, Mohammad Sohidul Islam4, Ayman El Sabagh5,6,*, Magdi T. Abdelhamid2,7,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1623-1645, 2024, DOI:10.32604/phyton.2024.054453 - 30 July 2024

    Abstract While Egypt’s canola production per unit area has recently grown, productivity remains low, necessitating increased productivity. Hydrogels are water-absorbent polymer compounds that can optimize irrigation schedules by increasing the soil’s ability to retain water. Accordingly, two field experiments were conducted to examine hydrogel application to sandy soil on canola growth, biochemical aspects, yield, yield traits, and nutritional quality of yielded seeds grown under water deficit stress conditions. The experiments were conducted by arranging a split-plot layout in a randomized complete block design (RCBD) with three times replications of each treatment. While water stress at 75%… More >

  • Open Access

    ARTICLE

    Cu Stress-Induced Transcriptome Alterations in Sorghum and Expression Analysis of the Transcription Factor-Encoding Gene SbWRKY24

    Mingchuan Yang1, Jia Zheng2, Wenhui Yu1, Yanghua Li2, Yali Wang1, Zilu Zhang1, Zhenhui Kang1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1503-1521, 2024, DOI:10.32604/phyton.2024.051718 - 30 July 2024

    Abstract Sorghum is not only an important bio-energy crop but also a vital raw material for brewing. Exogenous copper affects the growth and metabolism of crops in specific ways. This study identified 8475 differentially expressed genes (DEGs) by high-throughput transcriptome sequencing in the sorghum cultivar ‘Jinnuoliang 2’ after 24 h of treatment with 10 mM CuSO. Using GO analysis, 476 genes were functionally annotated, which were mainly related to catabolism and biosynthetic processes. Additionally, 90 pathways were annotated by employing the KEGG analysis. Among them, glutathione metabolism and peroxisome were induced, while photosynthesis, photosynthesis-antenna protein, and… More >

  • Open Access

    ARTICLE

    Physiological Response Mechanism and Drought Resistance Evaluation of Passiflora edulis Sims under Drought Stress

    Binyang Zhao1, Fengchan Wu2, Guojun Cai3, Peiyu Xi2, Yulin Guo2, Anding Li2,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1345-1363, 2024, DOI:10.32604/phyton.2024.050950 - 27 June 2024

    Abstract In order to explore the response mechanism of Passiflora edulis Sims to drought stress, the changes in morphological and physiological traits of Passiflora edulis Sims under different drought conditions were studied. A total of 7 germplasm resources of Passiflora edulis Sims were selected and tested under drought stress by the pot culture method under 4 treatment levels: 75%–80% (Control, CK) of maximum field water capacity, 55%–60% (Light Drought, LD) of maximum field water capacity, i.e., mild drought, 40%–45% (Moderate Drought, MD) of maximum field water capacity, i.e., moderate drought and 30%–35% (Severe Drought, SD) of maximum field water… More >

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