Jizeng Wang^*, Jin Qian^*, Huajian Gao^∗,†

Molecular & Cellular Biomechanics, Vol.5, No.1, pp. 19-26, 2008, DOI:10.3970/mcb.2008.005.019

Abstract Experiments have shown that stable adhesion of a variety of animal cells on substrates prepared with precisely controlled ligand distribution can be formed only if the ligand spacing is below 58 nm. To explain this phenomenon, here we propose a confined polymer model to study the stability of molecular adhesion mediated by polymer repellers and ligand-receptor bonds. In this model, both repellers and binders are treated as wormlike chains confined in a nanoslit, and the stability of adhesion is considered as a competition between attractive interactions of ligand-receptor binding and repulsive forces due to the size mismatch between repellers and… More >

Shaohua Hu^*, Ning Wang^†

Molecular & Cellular Biomechanics, Vol.3, No.2, pp. 49-60, 2006, DOI:10.3970/mcb.2006.003.049

Abstract One fundamental question in cell biology is how mechanical stresses are distributed inside the cytoplasm. Recently we have developed a synchronous detection approach to map cytoplasmic displacements and stresses using yellow fluorescent protein tagged mitochondria as fiducial markers of the cytoskeleton (CSK) in response to a localized load applied via an RGD-coated magnetic bead (7). We have shown that stresses are propagated to remote sites in the cytoplasm, a finding that contradicts continuum model predictions. Here we show that long distance force propagation in the cytoplasm was abolished when the contractile prestress in the CSK was lowered by relaxing agents… More >

Morakot Likhitpanichkul¹, X. Edward Guo², Van C. Mow^1,3

Molecular & Cellular Biomechanics, Vol.2, No.4, pp. 191-204, 2005, DOI:10.3970/mcb.2005.002.191

Abstract Thorough analyses of the mechano-electrochemical interaction between articular cartilage matrix and the chondrocytes are crucial to understanding of the signal transduction mechanisms that modulate the cell metabolic activities and biosynthesis. Attempts have been made to model the chondrocytes embedded in the collagen-proteoglycan extracellular matrix to determine the distribution of local stress-strain field, fluid pressure and the time-dependent deformation of the cell. To date, these models still have not taken into account a remarkable characteristic of the cartilage extracellular matrix given rise from organization of the collagen fiber architecture, now known as the tension-compression nonlinearity (TCN) of the tissue, as well… More >

Shouqin Lü¹, Mian Long^1,2

Molecular & Cellular Biomechanics, Vol.2, No.4, pp. 161-178, 2005, DOI:10.3970/mcb.2005.002.161

Abstract Selectin-ligand interactions are crucial to such biological processes as inflammatory cascade or tumor metastasis. How transient formation and dissociation of selectin-ligand bonds in blood flow are coupled to molecular conformation at atomic level, however, has not been well understood. In this study, steered molecular dynamics (SMD) simulations were used to elucidate the intramolecular and intermolecular conformational evolutions involved in forced dissociation of three selectin-ligand systems: the construct consisting of P-selectin lectin (Lec) and epidermal growth factor (EGF)-like domains (P-LE) interacting with synthesized sulfoglycopeptide or SGP-3, P-LE with sialyl Lewis X (sLe^X), and E-LE with sLe^X. SMD simulations were based on… More >

Marco Orellana¹, Jordi Selga¹, Paris Vélez¹, Marc Sans¹, Ana Rodríguez², Vicente Boria², Ferran Martín¹

CMC-Computers, Materials & Continua, Vol.52, No.3, pp. 159-174, 2016, DOI:10.3970/cmc.2016.052.157

Abstract This paper is focused on the automated synthesis of wideband bandpass filters operating at microwave frequencies and based on electromagnetic bandgap (EBG) structures. The classical counterpart of such filter consists of a combination of transmission line sections and shunt-connected grounded stubs placed at equidistant positions. By replacing the transmission line sections with capacitively-loaded lines (a kind of EBG-based lines) exhibiting the same phase shift at the lower cutoff frequency and the same characteristic (actually Bloch) impedance, filter size is reduced and the spurious pass bands can be efficiently suppressed. In practice, the loading capacitances are implemented by means of patches,… More >

Xiaorong Zhao¹, Hongjin Zhu¹, Peizhong Shi¹, Chunpeng Ge², Xiufang Qian^1,*, Honghui Fan¹, Zhongjun Fu¹

CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 133-145, 2019, DOI:10.32604/cmc.2019.05661

Abstract With the rapid development of ultra-wideband communications, the design requirements of CMOS radio frequency integrated circuits have become increasingly high. Ultra-wideband (UWB) low noise amplifiers are a key component of the receiver front end. The paper designs a high power gain (S₂₁) and low noise figure (NF) common gate (CG) CMOS UWB low noise amplifier (LNA) with an operating frequency range between 3.1 GHz and 10.6 GHz. The circuit is designed by TSMC 0.13 μm RF CMOS technology. In order to achieve high gain and flat gain as well as low noise figure, the circuit uses many technologies. To improve… More >

Wen Tian¹, Xiaopeng Ji^1,*, Weiwei Liu¹, Guangjie Liu¹, Rong Lin^1,2, Jiangtao Zhai³, Yuewei Dai³

CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 193-211, 2019, DOI:10.32604/cmc.2019.05290

Abstract Cyber-physical system (CPS) is an advanced system that integrats physical processes, computation and communication resources. The security of cyber-physical systems has become an active research area in recent years. In this paper, we focus on defensive strategies against network attacks in CPS. We introduce both low- and highinteraction honeypots into CPS as a security management tool deliberately designed to be probed, attacked and compromised. In addition, an analysis resource constraint is introduced for the purpose of optimizing defensive strategies against network attacks in CPS. We study the offensive and defensive interactions of CPS and model the offensive and defensive process… More >

Dae-Young Kim¹, Se Dong Min^{2, †}, Seokhoon Kim^{3, †, *}

CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 1-14, 2019, DOI:10.32604/cmc.2019.06102

Abstract The importance of Blockchain and IoT technology have been highlighted in various fields. These are not unaccustomed words anymore in our lives. Although the technologies are in the infancy step and are still many remaining technical challenges, there is no doubt that it will be one of the major parts of the future Internet. The efficiency and security of data transmission scheme have always been major issues in the legacy Internet, and a data transmission scheme for the future Internet, including 5G and IoT environment should also provide and support these issues. Consequently, we propose a new data transmission scheme… More >

Muhammad Shoaib Arif^1,*, Ali Raza¹, Muhammad Rafiq², Mairaj Bibi³, Rabia Fayyaz³, Mehvish Naz³, Umer Javed⁴

CMC-Computers, Materials & Continua, Vol.59, No.3, pp. 787-804, 2019, DOI:10.32604/cmc.2019.04655

Abstract In this paper, a reliable stochastic numerical analysis for typhoid fever incorporating with protection against infection has been considered. We have compared the solutions of stochastic and deterministic typhoid fever model. It has been shown that the stochastic typhoid fever model is more realistic as compared to the deterministic typhoid fever model. The effect of threshold number T* hold in stochastic typhoid fever model. The proposed framework of the stochastic non-standard finite difference scheme (SNSFD) preserves all dynamical properties like positivity, bounded-ness and dynamical consistency defined by Mickens, R. E. The stochastic numerical simulation of the model showed that increase… More >

Lina Shi¹, Zichi Wang¹, Zhenxing Qian^1,*, Nannan Huang¹, Pauline Puteaux², Xinpeng Zhang¹

CMC-Computers, Materials & Continua, Vol.59, No.3, pp. 943-953, 2019, DOI:10.32604/cmc.2019.05768

Abstract Nowadays, emoji image is widely used in social networks. To achieve covert communication in emoji images, this paper proposes a distortion function for emoji images steganography. The profile of image content, the intra- and inter-frame correlation are taken into account in the proposed distortion function to fit the unique properties of emoji image. The three parts are combined together to measure the risks of detection due to the modification on the cover data. With the popular syndrome trellis coding (STC), the distortion of stego emoji image is minimized using the proposed distortion function. As a result, less detectable artifacts could… More >