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  • Open Access

    ARTICLE

    CBX4 Drives Gastric Cancer Progression by Activating β-Catenin Signaling

    Wendong Jia#, Ting Zhang#, Ziying Zhang, Lingzhi Wu, Xihao Fu, Zhenxin Wang*, Ni Yin*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068651 - 30 December 2025

    Abstract Objectives: Chromobox 4 (CBX4), a polycomb protein family member linked to tumor pathogenesis via dysregulation, has an incompletely defined role in gastric cancer (GC). The study aimed to investigate the role and mechanism of CBX4 in GC progression and evaluate its potential as a therapeutic target. Methods: CBX4 expression was assessed in GC tissues vs. adjacent non-cancerous tissues and in GC cell lines vs. normal gastric mucosal epithelial cells. Clinicopathological correlations were analyzed. Functional impacts of CBX4 were determined using knockdown and overexpression models in vitro (cell proliferation, migration, invasion) and in vivo (xenograft tumorigenesis in nude… More >

  • Open Access

    ARTICLE

    GFL-SAR: Graph Federated Collaborative Learning Framework Based on Structural Amplification and Attention Refinement

    Hefei Wang, Ruichun Gu*, Jingyu Wang, Xiaolin Zhang, Hui Wei

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-20, 2026, DOI:10.32604/cmc.2025.069251 - 10 November 2025

    Abstract Graph Federated Learning (GFL) has shown great potential in privacy protection and distributed intelligence through distributed collaborative training of graph-structured data without sharing raw information. However, existing GFL approaches often lack the capability for comprehensive feature extraction and adaptive optimization, particularly in non-independent and identically distributed (NON-IID) scenarios where balancing global structural understanding and local node-level detail remains a challenge. To this end, this paper proposes a novel framework called GFL-SAR (Graph Federated Collaborative Learning Framework Based on Structural Amplification and Attention Refinement), which enhances the representation learning capability of graph data through a dual-branch… More >

  • Open Access

    ARTICLE

    Genome-Wide Identification and Functional Characterization of UGT Gene Family in Sorghum bicolor with Insights into SbUGT12’s Role in C4 Photosynthesis

    Wenxiang Zhang1,2, Wenning Cui1, Juan Huang3, Zhangen Lu1, Kuijing Liang1, Lingbao Wang1,2, Shanshan Wei1,2, Liran Shi1, Huifen Li1, Xiaoli Guo1,2,*, Jianhui Ma4,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3893-3912, 2025, DOI:10.32604/phyton.2025.073736 - 29 December 2025

    Abstract UDP-glycosyltransferases (UGTs) play essential roles in plant secondary metabolism and stress responses, yet their composition and functions in Sorghum bicolor, a model C4 plant, remain inadequately characterized. This study identified 196 SbUGT genes distributed across all 10 chromosomes and classified them into 16 subfamilies (A–P) through phylogenetic analysis. Among these, 61.2% were intronless, and 10 conserved motifs, including the UGT-specific PSPG box, were identified. Synteny analysis using MCScanX revealed 12 segmental duplication events and conserved syntenic relationships with other Poaceae species (rice, maize, and barley). Promoter analysis uncovered 125 distinct cis-acting elements, predominantly associated with stress and… More >

  • Open Access

    ARTICLE

    Chemical Composition and Antifungal Efficacy of Mentha rotundifolia Essential Oil against Fusarium oxysporum f. sp. albedinis in Date Palm: Valorisation of Plant Biomass for Natural Antifungal Agents

    Hafida Khelafi1, Wassima Lakhdari2, Mustapha Mounir Bouhenna3, Said Boudeffeur4, Hayet Meamiche1, Salah Neghmouche Nacer5,*, Meriam Laouar6

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3975-3989, 2025, DOI:10.32604/phyton.2025.073210 - 29 December 2025

    Abstract Essential oils (EOs) derived from medicinal plants are gaining recognition as sustainable alternatives to synthetic fungicides in the management of plant pathogens. This study investigates the chemical composition, chromatographic profile, and antifungal of Mentha rotundifolia essential oil against Fusarium oxysporum f. sp. albedinis (Foa), the pathogen responsible for Bayoud disease in date palm. The oil was extracted through hydrodistillation and characterized using thin-layer chromatography (TLC) and gas chromatography–mass spectrometry (GC-MS), revealing multiple fractions corresponding to terpenoid constituents and 23 chemical constituents, predominantly oxygenated monoterpenes (68.51%), with piperitenone oxide as the major component (62.53%). The antifungal efficacy was evaluated… More >

  • Open Access

    ARTICLE

    E-AAPIV: Merkle Tree-Based Real-Time Android Manifest Integrity Verification for Mobile Payment Security

    Mostafa Mohamed Ahmed Mohamed Alsaedy1,*, Atef Zaki Ghalwash1, Aliaa Abd Elhalim Yousif2, Safaa Magdy Azzam1

    Journal of Cyber Security, Vol.7, pp. 653-674, 2025, DOI:10.32604/jcs.2025.073547 - 24 December 2025

    Abstract Mobile financial applications and payment systems face significant security challenges from reverse engineering attacks. Attackers can decompile Android Package Kit (APK) files, modify permissions, and repackage applications with malicious capabilities. This work introduces E-AAPIV (Enhanced Android Apps Permissions Integrity Verifier), an advanced framework that uses Merkle Tree technology for real-time manifest integrity verification. The proposed system constructs cryptographic Merkle Tree from AndroidManifest.xml permission structures. It establishes secure client-server connections using Elliptic Curve Diffie-Hellman Protocol (ECDH-P384) key exchange. Root hashes are encrypted with Advanced Encryption Standard-256-Galois/Counter Mode (AES-256-GCM), integrated with hardware-backed Android Keystore for enhanced security. More >

  • Open Access

    ARTICLE

    Development of AgCuS nanostructures with optimized photocatalytic efficiency under solar irradiation

    S. Younus, N. Amin*, A. Ali, K. Mahmood

    Chalcogenide Letters, Vol.22, No.10, pp. 905-915, 2025, DOI:10.15251/CL.2025.2210.905

    Abstract Wastewater generated by the textile industry contains high levels of various pollutants. Advanced conventional methods, such as chemical and electrical treatments, are effective in addressing these contaminants. However, the significant operational and capital costs associated with these conventional systems limit their accessibility for industrial stakeholders. In contrast, more economically viable methods tend to be less efficient. This study aims to identify a suitable approach for integrating photocatalytic degradation (PCD) with a low-cost method to enhance the cost-effectiveness of wastewater treatment processes in the textile sector. The study utilized silver copper sulfide (AgCuS) nanocomposites as a… More >

  • Open Access

    ARTICLE

    GC-MS Analysis and Tyrosinase Inhibitory Potential of Pimenta dioica Flower Essential Oil

    Heba A. S. El-Nashar1,*, Ahmed T. Negmeldin2,3,*, Aziza El Baz4, Marizé Cuyler5, Brandon Alston5, Namrita Lall5,6,7, Naglaa S. Ashmawy1,8,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3269-3281, 2025, DOI:10.32604/phyton.2025.067998 - 29 October 2025

    Abstract Pimenta dioica is a tropical Caribbean tree belonging to the family Myrtaceae, widely used in various human activities, including perfume production, food flavoring, natural pesticides, and medicine. This study aimed to explore the chemical composition of Pimenta dioica flower essential oil obtained via hydrodistillation using GC-MS analysis. Additionally, the oil’s tyrosinase inhibitory activity was investigated. The effectiveness of the oil’s major constituents in binding to tyrosinase was also evaluated through molecular docking simulations. GC-MS analysis identified fifteen compounds, with eugenol (70.59%) as the major component, followed by β-myrcene (10.54%), limonene (8.55%), β-ocimene (4.92%), α-phellandrene (1.39%), and linalool… More >

  • Open Access

    ARTICLE

    Traffic Profiling and Secure Virtualized Data Handling of 5G Networks via MinIO Storage

    Khawaja Tahir Mehmood1,*, Muhammad Majid Hussain2

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5643-5670, 2025, DOI:10.32604/cmc.2025.068404 - 23 October 2025

    Abstract In the modern era of 5th generation (5G) networks, the data generated by User Equipments (UE) has increased significantly, with data file sizes varying from modest sensor logs to enormous multimedia files. In modern telecommunications networks, the need for high-end security and efficient management of these large data files is a great challenge for network designers. The proposed model provides the efficient real-time virtual data storage of UE data files (light and heavy) using an object storage system MinIO having inbuilt Software Development Kits (SDKs) that are compatible with Amazon (S3) Application Program Interface (API)… More >

  • Open Access

    RETRACTION

    Retraction: CSTB Downregulation Promotes Cell Proliferation and Migration and Suppresses Apoptosis in Gastric Cancer SGC-7901 Cell Line

    Oncology Research Editorial Office

    Oncology Research, Vol.33, No.11, pp. 3605-3605, 2025, DOI:10.32604/or.2025.074402 - 22 October 2025

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Variable Integral Parameter Control Strategy for Secondary Frequency Regulation with Multiple Energy Storage Units

    Jinyu Guo*, Xingxu Zhu, Zezhong Liu, Cuiping Li

    Energy Engineering, Vol.122, No.10, pp. 3961-3983, 2025, DOI:10.32604/ee.2025.067811 - 30 September 2025

    Abstract In high-renewable-energy power systems, the demand for fast-responding capabilities is growing. To address the limitations of conventional closed-loop frequency control, where the integral coefficient cannot dynamically adjust the frequency regulation command based on the state of charge (SoC) of energy storage units, this paper proposes a secondary frequency regulation control strategy based on variable integral coefficients for multiple energy storage units. First, a power-uniform controller is designed to ensure that thermal power units gradually take on more regulation power during the frequency regulation process. Next, a control framework based on variable integral coefficients is proposed… More >

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