YUANLIN LIU^1,3,#, YAN LIU^2,#, YAN WANG², QIANG WANG², YAN YAN¹, DANDAN ZHANG^2,*, HUIQIN LIU^2,*

Oncology Research, Vol.32, No.7, pp. 1221-1229, 2024, DOI:10.32604/or.2024.047454

Abstract At present, the role of many long non-coding RNAs (lncRNAs) as tumor suppressors in the formation and development of cervical cancer (CC) has been studied. However, lncRNA prostate cancer gene expression marker 1 (PCGEM1), whose high expression not only aggravates ovarian cancer but also can induce tumorigenesis and endometrial cancer progression, has not been studied in CC. The objective of this study was to investigate the expression and the underlying role of PCGEM1 in CC. The relative expression of PCGEM1 in CC cells was detected by real-time PCR. After the suppression of PCGEM1 expression by… More > Graphic Abstract

XIAOBI HUANG^1,#, CHUNYUAN CHEN², YONGYANG CHEN^1,#, HONGLIAN ZHOU¹, YONGHUA CHEN¹, ZHONG HUANG¹, YULIU XIE¹, BAIYANG LIU¹, YUDONG GUO¹, ZHIXIONG YANG¹, GUANGHUA CHEN^3,*, WENMEI SU^1,4,*

Oncology Research, Vol.32, No.7, pp. 1185-1195, 2024, DOI:10.32604/or.2023.030771

Abstract Background: Long non-coding RNAs are important regulators in cancer biology and function either as tumor suppressors or as oncogenes. Their dysregulation has been closely associated with tumorigenesis. LINC00265 is upregulated in lung adenocarcinoma and is a prognostic biomarker of this cancer. However, the mechanism underlying its function in cancer progression remains poorly understood. Methods: Here, the regulatory role of LINC00265 in lung adenocarcinoma was examined using lung cancer cell lines, clinical samples, and xenografts. Results: We found that high levels of LINC00265 expression were associated with shorter overall survival rate of patients, whereas knockdown of LINC00265 inhibited proliferation… More >

Jiahui Liu^1,2, Lang Li^1,2,*, Di Li^1,2, Yu Ou^1,2

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4641-4657, 2024, DOI:10.32604/cmc.2024.051613

Abstract Correlation power analysis (CPA) combined with genetic algorithms (GA) now achieves greater attack efficiency and can recover all subkeys simultaneously. However, two issues in GA-based CPA still need to be addressed: key degeneration and slow evolution within populations. These challenges significantly hinder key recovery efforts. This paper proposes a screening correlation power analysis framework combined with a genetic algorithm, named SFGA-CPA, to address these issues. SFGA-CPA introduces three operations designed to exploit CPA characteristics: propagative operation, constrained crossover, and constrained mutation. Firstly, the propagative operation accelerates population evolution by maximizing the number of correct bytes… More >

Djeldjli Halima^1,*, Benatiallah Djelloul¹, Ghasri Mehdi², Tanougast Camel³, Benatiallah Ali⁴, Benabdelkrim Bouchra¹

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4725-4740, 2024, DOI:10.32604/cmc.2024.051002

Abstract When designing solar systems and assessing the effectiveness of their many uses, estimating sun irradiance is a crucial first step. This study examined three approaches (ANN, GA-ANN, and ANFIS) for estimating daily global solar radiation (GSR) in the south of Algeria: Adrar, Ouargla, and Bechar. The proposed hybrid GA-ANN model, based on genetic algorithm-based optimization, was developed to improve the ANN model. The GA-ANN and ANFIS models performed better than the standalone ANN-based model, with GA-ANN being better suited for forecasting in all sites, and it performed the best with the best values in the… More > Graphic Abstract

Junqing Bai¹, Qiuchao Dai^1,*, Yingying Li²

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 5083-5103, 2024, DOI:10.32604/cmc.2024.050921

Abstract To support the explosive growth of Information and Communications Technology (ICT), Mobile Edge Computing (MEC) provides users with low latency and high bandwidth service by offloading computational tasks to the network’s edge. However, resource-constrained mobile devices still suffer from a capacity mismatch when faced with latency-sensitive and compute-intensive emerging applications. To address the difficulty of running computationally intensive applications on resource-constrained clients, a model of the computation offloading problem in a network consisting of multiple mobile users and edge cloud servers is studied in this paper. Then a user benefit function EoU (Experience of Users) is… More >

Cheng Yang^1,2, Miaojia Lou^2,*, Xiaoyu Chen^1,2, Zixuan Ren¹

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4107-4126, 2024, DOI:10.32604/cmc.2024.049183

Abstract Chinese shadow puppetry has been recognized as a world intangible cultural heritage. However, it faces substantial challenges in its preservation and advancement due to the intricate and labor-intensive nature of crafting shadow puppets. To ensure the inheritance and development of this cultural heritage, it is imperative to enable traditional art to flourish in the digital era. This paper presents an Interactive Collaborative Creation System for shadow puppets, designed to facilitate the creation of high-quality shadow puppet images with greater ease. The system comprises four key functions: Image contour extraction, intelligent reference recommendation, generation network, and… More >

Mahatir Ahmed Tusher¹, Saket Choudary Kongara¹, Sagar Dhanraj Pande², SeongKi Kim^3,*, Salil Bharany^4,*

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4063-4080, 2024, DOI:10.32604/cmc.2024.049007

Abstract The challenging task of handwriting style synthesis requires capturing the individuality and diversity of human handwriting. The majority of currently available methods use either a generative adversarial network (GAN) or a recurrent neural network (RNN) to generate new handwriting styles. This is why these techniques frequently fall short of producing diverse and realistic text pictures, particularly for terms that are not commonly used. To resolve that, this research proposes a novel deep learning model that consists of a style encoder and a text generator to synthesize different handwriting styles. This network excels in generating conditional… More >

Abdulelah Alwabel^1,*, Chinmaya Kumar Swain²

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4127-4148, 2024, DOI:10.32604/cmc.2024.048833

Abstract Fog computing has recently developed as a new paradigm with the aim of addressing time-sensitive applications better than with cloud computing by placing and processing tasks in close proximity to the data sources. However, the majority of the fog nodes in this environment are geographically scattered with resources that are limited in terms of capabilities compared to cloud nodes, thus making the application placement problem more complex than that in cloud computing. An approach for cost-efficient application placement in fog-cloud computing environments that combines the benefits of both fog and cloud computing to optimize the… More >

Chao-Lung Yang^1,*, Melkamu Mengistnew Teshome¹, Yu-Zhen Yeh¹, Tamrat Yifter Meles²

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 3519-3547, 2024, DOI:10.32604/cmc.2024.048462

Abstract In this study, we introduce a novel multi-objective optimization model tailored for modern manufacturing, aiming to mitigate the cost impacts of operational disruptions through optimized corrective maintenance. Central to our approach is the strategic placement of maintenance stations and the efficient allocation of personnel, addressing a crucial gap in the integration of maintenance personnel dispatching and station selection. Our model uniquely combines the spatial distribution of machinery with the expertise of operators to achieve a harmonious balance between maintenance efficiency and cost-effectiveness. The core of our methodology is the NSGA III+ Dispatch, an advanced adaptation… More >

Mutasem K. Alsmadi^*

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 5175-5200, 2024, DOI:10.32604/cmc.2024.044065

Abstract Lung cancer is among the most frequent cancers in the world, with over one million deaths per year. Classification is required for lung cancer diagnosis and therapy to be effective, accurate, and reliable. Gene expression microarrays have made it possible to find genetic biomarkers for cancer diagnosis and prediction in a high-throughput manner. Machine Learning (ML) has been widely used to diagnose and classify lung cancer where the performance of ML methods is evaluated to identify the appropriate technique. Identifying and selecting the gene expression patterns can help in lung cancer diagnoses and classification. Normally,… More >