Akanksha Tiwari^1,*, Ram Bilas Pachori^1,2, Premjit Khanganba Sanjram^1,3,4

CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 887-905, 2022, DOI:10.32604/cmc.2022.023886

Abstract Computer gaming is one of the most common activities that individuals are indulged in their usual activities concerning interactive system-based entertainment. Visuospatial processing is an essential aspect of mental rotation (MR) in playing computer-games. Previous studies have explored how objects’ features affect the MR process; however, non-isomorphic 2D and 3D objects lack a fair comparison. In addition, the effects of these features on brain activation during the MR in computer-games have been less investigated. This study investigates how dimensionality and angular disparity affect brain activation during MR in computer-games. EEG (electroencephalogram) data were recorded from sixty healthy adults while playing… More >

YAO XU^1,#, BIN WU^2,#, JING YANG³, SHENG ZHANG², LONGGEN LIU⁴, SUOBAO XU^2,*, JIAKAI JIANG^2,*

BIOCELL, Vol.46, No.6, pp. 1483-1491, 2022, DOI:10.32604/biocell.2022.017745

Abstract To study the roles and association of murine double minute gene 2 (MDM2) and fructose-1,6-biphosphatase (FBP1) in human hepatocellular carcinoma (HCC), growth response of human HCC cells was assessed using proliferation and apoptosis assay. Pro-survival AKT signaling associated proteins (p-AKT, survivin and cleaved caspase 3) were assessed using western blotting. The correlation between MDM2 and FBP1 was assessed using co-immunoprecipitation combined with ubiquitination assay. Our data suggested that low expression of FBP1 was correlated with high levels of MDM2 in HCC cell lines (Huh7 and Hep3B). Overexpression of FBP1 resulted in anti-proliferation, pro-apoptosis, the up-regulation of cleaved caspase 3 while… More >

Li Wang^1,2,#, Rongbai Tong^3,#, Juanli Wang^1,2,*, Jintao Wan^1,2,*, Yuhu Li^1,2, Pujun Jin^1,2, Daodao Hu^1,2

Journal of Renewable Materials, Vol.10, No.5, pp. 1349-1364, 2022, DOI:10.32604/jrm.2022.019372

Abstract Quest for bio-based halogen-free green flame retardant has attracted many concerns in recent years. Herein a reactive functional flame retardant containing phosphorus VDP is synthesized from vanillin, 9,10-dihydro-9-oxa-10-phosphophene-10-oxide (DOPO) and phenol via a facile way. VDP is characterized with ¹H NMR, ³¹P NMR, FTIR and Time of Flight Mass Spectrometry, and used as a new reactive flame retardant for bisphenol epoxy thermosets. Thermogravimetry analysis shows that when the VDP loading is only 0.5P% (based on phosphorus content), the residue increases from 14.2% to 21.1% at 750°C in N₂ compare with neat DGEBA. Correspondingly, the limit oxygen index increased to 29.6%,… More >

KATARINA BARALIć^1,*, KATARINA ŽIVANčEVIć¹, DRAGICA BoŽIĆ¹, DANYEL JENNEN², ALEKSANDRA BUHA DJORDJEVIC¹, EVICA ANTONIJEVIć MILJAKOVIć¹, DANIJELA ĐUKIć-ĆOSIć¹

BIOCELL, Vol.46, No.2, pp. 519-533, 2022, DOI:10.32604/biocell.2022.018271

Abstract This in silico toxicogenomic study aims to explore the relationship between phthalates and bisphenol A (BPA) co-exposure and obesity, as well as its comorbid conditions, in order to construct a possible set of genomic biomarkers. The Comparative Toxicogenomics Database (CTD; http://ctd.mdibl.org) was used as the main data mining tool, along with GeneMania (https://genemania.org), ToppGene Suite (https://toppgene.cchmc.org) and DisGeNET (http://www.disgenet.org). Among the phthalates, bis(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) were chosen as the most frequently curated phthalates in CTD, which also share similar mechanisms of toxicity. DEHP, DBP and BPA interacted with 84, 90 and 194 obesity-related genes/proteins, involved in… More >

RAFAEL MORENO-GÓMEZ-TOLEDANO^1,*, MARíA I. ARENAS², ESPERANZA VÉLEZ-VÉLEZ³, RICARDO J. BOSCH¹

BIOCELL, Vol.46, No.2, pp. 305-308, 2022, DOI:10.32604/biocell.2022.017894

Abstract Bisphenol A (BPA) is a xenoestrogen known for its implications for the endocrine systems and several other organs, including the kidneys. Recent renal studies have shown that BPA can induce alterations of the cytoskeleton and cell adhesion mechanisms such as a podocytopathy with proteinuria and hypertension, alterations involved in the progression of renal diseases. These data and the fact that BPA is known to be present in the urine of almost the entire population strongly suggest the critical need to reevaluate BPA exposures considered safe. More >

Zehba A. S. Raizah¹, Abdelraheem M. Aly^1,2,*

CMC-Computers, Materials & Continua, Vol.66, No.3, pp. 3233-3251, 2021, DOI:10.32604/cmc.2021.012402

Abstract This study simulates natural convection flow resulting from heat partitions in an H-shaped enclosure filled with a nanofluid using an incompressible smoothed particle hydrodynamics (ISPH) method. The right area of the H-shaped enclosure is saturated with non-Darcy porous media. The center variable partitions of the H-shaped enclosure walls are kept at a high-temperature T_h. The left and right walls of the H-shaped enclosure are positioned at a low temperature T_c and the other walls are adiabatic. In ISPH method, the source term in pressure Poisson equation (PPE) is modified. The influences of the controlling parameters on the temperature distributions, the… More >

Abdelraheem M. Aly^{1, 2, *}, Mitsuteru Asai³, Ehab Mahmoud Mohamed^{4, 5}

CMC-Computers, Materials & Continua, Vol.65, No.1, pp. 205-224, 2020, DOI:10.32604/cmc.2020.09227

Abstract In the present work, an incompressible smoothed particle hydrodynamic (SPH) method is introduced to simulate water-soil-structure interactions. In the current calculation, the water is modelled as a Newtonian fluid. The soil is modelled in two different cases. In the first case, the granular material is considered as a fluid where a Bingham type constitutive model is proposed based on Mohr-Coulomb yield-stress criterion, and the viscosity is derived from the cohesion and friction angle. In addition, the fictitious suspension layers between water and soil depending on the concentration of soil are introduced. In the second case, Hooke’s law introduces elastic soil.… More >