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  • Open Access

    ARTICLE

    Circ_0053943 complexed with IGF2BP3 drives uveal melanoma progression via regulating N6-methyladenosine modification of Epidermal growth factor receptor

    ANDI ZHAO1,2,#, YUE WANG3,#, ZIJIN WANG1,2, QING SHAO1,2, QI GONG1,2, HUI ZHU1,2, SHIYA SHEN1,2, HU LIU1,2,*, XUEJUAN CHEN1,2,*

    Oncology Research, Vol.32, No.5, pp. 983-998, 2024, DOI:10.32604/or.2024.045972

    Abstract Numerous studies have characterized the critical role of circular RNAs (circRNAs) as regulatory factors in the progression of multiple cancers. However, the biological functions of circRNAs and their underlying molecular mechanisms in the progression of uveal melanoma (UM) remain enigmatic. In this study, we identified a novel circRNA, circ_0053943, through re-analysis of UM microarray data and quantitative RT-PCR. Circ_0053943 was found to be upregulated in UM and to promote the proliferation and metastatic ability of UM cells in both in vitro and in vivo settings. Mechanistically, circ_0053943 was observed to bind to the KH1 and KH2 domains of insulin-like growth… More > Graphic Abstract

    <i>Circ_0053943</i> complexed with IGF2BP3 drives uveal melanoma progression via regulating N6-methyladenosine modification of <i>Epidermal growth factor receptor</i>

  • Open Access

    ARTICLE

    Detection of Student Engagement in E-Learning Environments Using EfficientnetV2-L Together with RNN-Based Models

    Farhad Mortezapour Shiri1,*, Ehsan Ahmadi2, Mohammadreza Rezaee1, Thinagaran Perumal1

    Journal on Artificial Intelligence, Vol.6, pp. 85-103, 2024, DOI:10.32604/jai.2024.048911

    Abstract Automatic detection of student engagement levels from videos, which is a spatio-temporal classification problem is crucial for enhancing the quality of online education. This paper addresses this challenge by proposing four novel hybrid end-to-end deep learning models designed for the automatic detection of student engagement levels in e-learning videos. The evaluation of these models utilizes the DAiSEE dataset, a public repository capturing student affective states in e-learning scenarios. The initial model integrates EfficientNetV2-L with Gated Recurrent Unit (GRU) and attains an accuracy of 61.45%. Subsequently, the second model combines EfficientNetV2-L with bidirectional GRU (Bi-GRU), yielding an accuracy of 61.56%. The… More >

  • Open Access

    ARTICLE

    Analysis of Color Landscape Characteristics in “Beautiful Village” of China Based on 3D Real Scene Models

    Yiyi Cen1,3, Wenzheng Jia2, Wen Dai3,*, Chun Wang4, He Wu1

    Revue Internationale de Géomatique, Vol.33, pp. 93-109, 2024, DOI:10.32604/rig.2024.050273

    Abstract Color, as a significant element of village landscapes, serves various functions such as enhancing aesthetic appeal and attractiveness, conveying emotions and cultural values. To explore the three-dimensional spatial characteristics of color landscapes in beautiful villages, this study conducted a comparative experiment involving eight provincial-level beautiful villages and eight ordinary villages in Jinzhai County. Landscape pattern indices were used to analyze the color landscape patterns on the facades of these villages, complemented by a quantitative analysis of color attributes using the Munsell color system. The results indicate that (1) Natural landscape colors in beautiful villages are primarily concentrated in the yellow-red… More >

  • Open Access

    ARTICLE

    A Deep Learning Model for Insurance Claims Predictions

    Umar Isa Abdulkadir*, Anil Fernando*

    Journal on Artificial Intelligence, Vol.6, pp. 71-83, 2024, DOI:10.32604/jai.2024.045332

    Abstract One of the significant issues the insurance industry faces is its ability to predict future claims related to individual policyholders. As risk varies from one policyholder to another, the industry has faced the challenge of using various risk factors to accurately predict the likelihood of claims by policyholders using historical data. Traditional machine-learning models that use neural networks are recognized as exceptional algorithms with predictive capabilities. This study aims to develop a deep learning model using sequential deep regression techniques for insurance claim prediction using historical data obtained from Kaggle with 1339 cases and eight variables. This study adopted a… More >

  • Open Access

    ARTICLE

    A Hand Features Based Fusion Recognition Network with Enhancing Multi-Modal Correlation

    Wei Wu*, Yuan Zhang, Yunpeng Li, Chuanyang Li, Yan Hao

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 537-555, 2024, DOI:10.32604/cmes.2024.049174

    Abstract Fusing hand-based features in multi-modal biometric recognition enhances anti-spoofing capabilities. Additionally, it leverages inter-modal correlation to enhance recognition performance. Concurrently, the robustness and recognition performance of the system can be enhanced through judiciously leveraging the correlation among multimodal features. Nevertheless, two issues persist in multi-modal feature fusion recognition: Firstly, the enhancement of recognition performance in fusion recognition has not comprehensively considered the inter-modality correlations among distinct modalities. Secondly, during modal fusion, improper weight selection diminishes the salience of crucial modal features, thereby diminishing the overall recognition performance. To address these two issues, we introduce an enhanced DenseNet multimodal recognition network… More > Graphic Abstract

    A Hand Features Based Fusion Recognition Network with Enhancing Multi-Modal Correlation

  • Open Access

    ARTICLE

    Decoupling Algorithms for the Gravitational Wave Spacecraft

    Xue Wang1,2, Weizhou Zhu1,2, Zhao Cui2,3, Xingguang Qian2,3, Jinke Yang1,2, Jianjun Jia1,2,*, Yikun Wang2,3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 325-337, 2024, DOI:10.32604/cmes.2024.048804

    Abstract The gravitational wave spacecraft is a complex multi-input multi-output dynamic system. The gravitational wave detection mission requires the spacecraft to achieve single spacecraft with two laser links and high-precision control. Establishing one spacecraft with two laser links, compared to one spacecraft with a single laser link, requires an upgraded decoupling algorithm for the link establishment. The decoupling algorithm we designed reassigns the degrees of freedom and forces in the control loop to ensure sufficient degrees of freedom for optical axis control. In addressing the distinct dynamic characteristics of different degrees of freedom, a transfer function compensation method is used in… More >

  • Open Access

    ARTICLE

    Effect of Modulus Heterogeneity on the Equilibrium Shape and Stress Field of α Precipitate in Ti-6Al-4V

    Di Qiu1,3,4, Rongpei Shi2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1017-1028, 2024, DOI:10.32604/cmes.2024.048797

    Abstract For media with inclusions (e.g., precipitates, voids, reinforcements, and others), the difference in lattice parameter and the elastic modulus between the matrix and inclusions cause stress concentration at the interfaces. These stress fields depend on the inclusions’ size, shape, and distribution and will respond instantly to the evolving microstructure. This study develops a phase-field model concerning modulus heterogeneity. The effect of modulus heterogeneity on the growth process and equilibrium state of the α plate in Ti-6Al-4V during precipitation is evaluated. The α precipitate exhibits strong anisotropy in shape upon cooling due to the interplay of the elastic strain and interfacial… More >

  • Open Access

    ARTICLE

    Application of the CatBoost Model for Stirred Reactor State Monitoring Based on Vibration Signals

    Xukai Ren1,2,*, Huanwei Yu2, Xianfeng Chen2, Yantong Tang2, Guobiao Wang1,*, Xiyong Du2

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 647-663, 2024, DOI:10.32604/cmes.2024.048782

    Abstract Stirred reactors are key equipment in production, and unpredictable failures will result in significant economic losses and safety issues. Therefore, it is necessary to monitor its health state. To achieve this goal, in this study, five states of the stirred reactor were firstly preset: normal, shaft bending, blade eccentricity, bearing wear, and bolt looseness. Vibration signals along x, y and z axes were collected and analyzed in both the time domain and frequency domain. Secondly, 93 statistical features were extracted and evaluated by ReliefF, Maximal Information Coefficient (MIC) and XGBoost. The above evaluation results were then fused by D-S evidence… More >

  • Open Access

    ARTICLE

    Finite Element Simulations of the Localized Failure and Fracture Propagation in Cohesive Materials with Friction

    Chengbao Hu1,2,3, Shilin Gong4,*, Bin Chen1,2,3, Zhongling Zong4, Xingwang Bao5, Xiaojian Ru5

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 997-1015, 2024, DOI:10.32604/cmes.2024.048640

    Abstract Strain localization frequently occurs in cohesive materials with friction (e.g., composites, soils, rocks) and is widely recognized as a fundamental cause of progressive structural failure. Nonetheless, achieving high-fidelity simulation for this issue, particularly concerning strong discontinuities and tension-compression-shear behaviors within localized zones, remains significantly constrained. In response, this study introduces an integrated algorithm within the finite element framework, merging a coupled cohesive zone model (CZM) with the nonlinear augmented finite element method (N-AFEM). The coupled CZM comprehensively describes tension-compression and compression-shear failure behaviors in cohesive, frictional materials, while the N-AFEM allows nonlinear coupled intra-element discontinuities without necessitating extra nodes or… More >

  • Open Access

    ARTICLE

    A Lightweight Network with Dual Encoder and Cross Feature Fusion for Cement Pavement Crack Detection

    Zhong Qu1,*, Guoqing Mu1, Bin Yuan2

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 255-273, 2024, DOI:10.32604/cmes.2024.048175

    Abstract Automatic crack detection of cement pavement chiefly benefits from the rapid development of deep learning, with convolutional neural networks (CNN) playing an important role in this field. However, as the performance of crack detection in cement pavement improves, the depth and width of the network structure are significantly increased, which necessitates more computing power and storage space. This limitation hampers the practical implementation of crack detection models on various platforms, particularly portable devices like small mobile devices. To solve these problems, we propose a dual-encoder-based network architecture that focuses on extracting more comprehensive fracture feature information and combines cross-fusion modules… More > Graphic Abstract

    A Lightweight Network with Dual Encoder and Cross Feature Fusion for Cement Pavement Crack Detection

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