Xiangmei Ye^1,2,3, Baoyi Yang⁴, Xin Zhang⁵, Luyuan Yang¹, Likun Zhang⁵, Qin Ren¹, Xiaobing Li¹, Leiguang Feng¹, Lanlan Wei^3,6,7,*, Peng Song¹, Yuqing Ye⁸, Xin Lian⁹, Yujuan Gao⁹, Haidi Tang¹, Zhiyu Liu¹

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068814 - 30 December 2025

Abstract Objectives: Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia and Philadelphia-like B-cell acute lymphoblastic leukemia (Ph+/Ph-like ALL) constitute the majority of relapsed/refractory B-ALL (R/R B-ALL) cases, highlighting an urgent need to discover new therapeutic targets. This study aims to elucidate the mechanisms underlying poor prognosis in Ph+/Ph-like ALL through transcriptome sequencing and functional cytological assays, with the goal of informing new clinical treatment strategies. Results: Transcriptomic analysis of Ph+/Ph-like ALL patients revealed that low expression of P2X Purinoceptor 1 (P2RX1) was associated with unfavorable outcomes. Specifically, patients with poor prognosis and low P2RX1 expression exhibited downregulation of… More >

Xiaopan Zou^1,2, Meiyang Sun³, Xin Jiang¹, Jingze Yu², Xiaomeng Li^4,*, Bingyu Nie^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.066662 - 30 December 2025

Abstract Objective: Triple-negative breast cancer (TNBC) is highly aggressive and lacks an effective targeted therapy. This study aimed to elucidate the functions and possible mechanisms of action of zinc finger miz-type containing 2 (ZMIZ2) and minichromosome maintenance complex component 3 (MCM3) in TNBC progression. Methods: The relationship between ZMIZ2 expression and clinical characteristics of TNBC was investigated. In vitro and in vivo experiments were performed to investigate the role of ZMIZ2 dysregulation in TNBC cell malignant behaviors. The regulatory relationship between ZMIZ2 and MCM3 was also explored. Transcriptome sequencing was performed to elucidate possible mechanisms underlying the ZMIZ2/MCM3… More >

Arshad Riaz^1,*, Misbah Ilyas¹, Muhammad Naeem Aslam², Safia Akram³, Sami Ullah Khan⁴, Ghaliah Alhamzi⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3481-3509, 2025, DOI:10.32604/cmes.2025.072513 - 23 December 2025

Abstract Peristaltic transport of non-Newtonian nanofluids with double diffusion is essential to biological engineering, microfluidics, and manufacturing processes. The authors tackle the key problem of Sisko nanofluids under double diffusion convection with thermal radiations and electroosmotic effects. The study proposes a solution approach by using Morlet-Wavelet Neural Networks that can effectively solve this complex problem by their superior ability in the capture of nonlinear dynamics. These convergence analyses were calculated across fifty independent runs. Theil’s Inequality Coefficient and the Mean Squared Error values range from 10⁻⁷ to 10⁻⁵ and 10⁻⁷ to 10⁻¹⁰, respectively. These values showed the proposed More >

U. Anwar^a, N. A. Noor^b, S. Mumtaz^c,*, I. M. Moussad¹

Chalcogenide Letters, Vol.22, No.3, pp. 261-276, 2025, DOI:10.15251/CL.2025.223.261

Abstract The combination of two-step synthesis processes is employed for the fabrication of (NiO)(_0.5)/(Fe₂O₃)(_0.5)@C@MoS₂ (NFCM) nanofibers composite through electrospinning and hydrothermal techniques. This nanofiber composite is designed for tunable dielectric materials and electromagnetic interference (EMI) shielding applications. Using impedance spectroscopy, the electrical properties of an NFCM pellet are analyzed using an equivalent circuit model (R₁1<), with a primary focus on the variation of relaxation time with frequency at different temperatures. Utilizing the Mott. variable range hopping (MVRH) model, and small polaronic hopping model, the localization length of the hoping carriers is determined to be 0.98 Å and More >

X. L. Guo^a, Y. F. Zhang^a,*, S. Y. Li^b, Q. Li^b, Q. Hao^c, X. Y. Ran^c, Y. M. Zhao^d

Chalcogenide Letters, Vol.22, No.4, pp. 313-330, 2025, DOI:10.15251/CL.2025.224.313

Abstract MoS₂ has excellent properties but low conductivity, limiting its use in supercapacitors. Carbon’s high conductivity and stability enhance MoS₂’s electrochemical performance and cycling stability. This study prepared MoS₂/C composites via a one-step hydrothermal method, exploring the effects of solvents and carbon content. Deionized water as a solvent resulted in composites with large specific surface areas and good electrochemical properties. Increasing carbon content improved electrochemical performance, peaking at a glucose content of 0.28 mmol, achieving a specific capacitance of 202.6 F/g. However, excessive carbon content led to decreased performance. More >

U. Anwar^a,, M. Rafi^b, N. A. Noor^c, S. Mumtaz^d,, Hosam O. Elansary^e

Chalcogenide Letters, Vol.22, No.4, pp. 293-311, 2025, DOI:10.15251/CL.2025.224.293

Abstract This study presents a multifunctional NiFe₂O₄@MoS₂ nanomaterial synthesized by co-precipitation and hydrothermal methods. The highly magnified Field emission scanning electron microscopic (FESEM) images expose an excellent interconnected network of MoS₂ petals and NiFe₂O₄ cores. NiFe₂O₄@MoS₂ nanomaterial's crystalline arrangement and phase purity are explored using X-ray diffraction (XRD) analysis. A comprehensive analysis of the NiFe₂O₄@MoS₂ nanomaterial, focusing on its dynamic electrical properties across a temperature zone of 183 K to 373 K. The temperature-dependent impedance and modulus plots versus frequency reveal insights into the material’s conduction and relaxation. Electrical characteristics verify the contribution of electroactive regions, such as grains… More >

C. B. Cui^a,b, G. C. Yang^b, Z. Zhang^a,, X. J. Wang^c,

Chalcogenide Letters, Vol.22, No.6, pp. 507-520, 2025, DOI:10.15251/CL.2025.226.507

Abstract This research introduces an innovative aptasensor for detecting alpha-fetoprotein with exceptional sensitivity and specificity, employing a novel MoS₂/Fe₃O₄ composite fabricated through an advanced in-situ growth methodology. The composite exhibited a hierarchical flower-like structure with uniformly distributed Fe3O4 nanoparticles, confirmed by SEM, XRD, and Raman spectroscopy. The MoS₂/Fe₃O₄ composite demonstrated a 66% increase in surface area (7.16 m^²/g) compared to pristine MoS2, enhancing aptamer immobilization and electron transfer efficiency. Electrochemical characterization revealed a significant increase in interfacial resistance upon AFP binding, with a detection limit of 0.3 pg/mL and a dual linear range of 0.001–0.1 ng/mL and 0.1–100 More >

K. Wang^a,b,*, G. L. Lian^c, Y. F. Qiao^d

Chalcogenide Letters, Vol.22, No.10, pp. 889-904, 2025, DOI:10.15251/CL.2025.2210.889

Abstract The remediation of acid mine drainage (AMD), characterized by its high concentrations of toxic metal ions and low pH, presents a significant environmental challenge. In this study, exfoliated two-dimensional MoS_₂ nanosheets were prepared using a liquid-phase ultrasonication method and evaluated for their efficiency in removing Cd^²⁺, Cu^²⁺, and Pb^²⁺ from aqueous solutions. Detailed structural and morphological analyses confirmed that the exfoliation process significantly enhanced surface area, pore volume, and exposure of reactive sulfur sites. Through isotherm and kinetic modeling analyses, the adsorption behavior was found to align with the Langmuir model and pseudo-second-order kinetic equation, which implies More >

Mohd Hakimi Abdul Rahman¹, Amir Sharifuddin Ab Latip^1,*, Zulkiflee Abd Latif^1,2, Siti Balqis Mohd Tun¹, Nur Azlina Hariffin¹, Mohd Fikri Razali³

Revue Internationale de Géomatique, Vol.34, pp. 959-972, 2025, DOI:10.32604/rig.2025.071109 - 12 December 2025

Abstract Atmospheric phase delay, primarily caused by water vapor in the troposphere, is a major source of error in InSAR measurements, especially for land subsidence monitoring. This study integrates GNSS and GACOS data to correct tropospheric delay and enhance InSAR accuracy in Banting, Selangor. A total of 27 Sentinel-1A images, 14 GNSS stations, and 27 corresponding GACOS ZTD maps were used to monitor subsidence between 2023 and 2025. The InSAR data were processed using SNAP, StaMPS, and the TRAIN toolbox, incorporating both GNSS- and GACOS-derived ZTD corrections. The results show that applying atmospheric correction improved the… More >

Amina Mahreen¹, Fateh Mebarek-Oudina^2,3,4,*, Amna Ashfaq¹, Jawad Raza¹, Sami Ullah Khan⁵, Hanumesh Vaidya⁶

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.11, pp. 2829-2853, 2025, DOI:10.32604/fdmp.2025.072492 - 01 December 2025

Abstract Understanding the complex interaction between heat and mass transfer in non-Newtonian microflows is essential for the development and optimization of efficient microfluidic and thermal management systems. This study investigates the magnetohydrodynamic (MHD) thermosolutal convection of a Casson fluid within an inclined, porous microchannel subjected to convective boundary conditions. The nonlinear, coupled equations governing momentum, energy, and species transport are solved numerically using the MATLAB bvp4c solver, ensuring high numerical accuracy and stability. To identify the dominant parameters influencing flow behavior and to optimize transport performance, a comprehensive hybrid optimization framework—combining a modified Taguchi design, Grey… More >