Abdu Salam¹, Mohammad Abrar², Raja Waseem Anwer³, Farhan Amin^4,*, Faizan Ullah⁵, Isabel de la Torre^6,*, Gerardo Mendez Mezquita⁷, Henry Fabian Gongora⁷

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2457-2479, 2025, DOI:10.32604/cmes.2025.072765 - 26 November 2025

Abstract Brain tumors pose significant diagnostic challenges due to their diverse types and complex anatomical locations. Due to the increase in precision image-based diagnostic tools, driven by advancements in artificial intelligence (AI) and deep learning, there has been potential to improve diagnostic accuracy, especially with Magnetic Resonance Imaging (MRI). However, traditional state-of-the-art models lack the sensitivity essential for reliable tumor identification and segmentation. Thus, our research aims to enhance brain tumor diagnosis in MRI by proposing an advanced model. The proposed model incorporates dilated convolutions to optimize the brain tumor segmentation and classification. The proposed model… More >

Jingcheng Lyu^1,2,#, Ruiyu Yue^1,2,#, Boyu Yang^1,2, Xuanhao Li^1,2, Jian Song^1,2,*

Canadian Journal of Urology, Vol.32, No.5, pp. 445-456, 2025, DOI:10.32604/cju.2025.068853 - 30 October 2025

Abstract Objectives: This study aimed to develop an artificial intelligence (AI)-based image recognition system using the nnU-Net adaptive neural network to assist clinicians in detecting magnetic resonance imaging (MRI)-invisible prostate cancer. The motivation stems from the diagnostic challenges, especially when MRI findings are inconclusive (Prostate Imaging Reporting and Data System [PI-RADS] score ≤ 3). Methods: We retrospectively included 150 patients who underwent systematic prostate biopsy at Beijing Friendship Hospital between January 2013 and January 2023. All were pathologically confirmed to have clinically significant prostate cancer, despite negative findings on preoperative MRI. A total of 1475 MRI… More >

Abdullah G. M. Almansour^1,*, Faisal Alshomrani², Abdulaziz T. M. Almutairi³, Easa Alalwany⁴, Mohammed S. Alshuhri¹, Hussein Alshaari⁵, Abdullah Alfahaid⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2395-2418, 2025, DOI:10.32604/cmes.2025.069661 - 31 August 2025

Abstract The early and precise identification of Alzheimer’s Disease (AD) continues to pose considerable clinical difficulty due to subtle structural alterations and overlapping symptoms across the disease phases. This study presents a novel Deformable Attention Vision Transformer (DA-ViT) architecture that integrates deformable Multi-Head Self-Attention (MHSA) with a Multi-Layer Perceptron (MLP) block for efficient classification of Alzheimer’s disease (AD) using Magnetic resonance imaging (MRI) scans. In contrast to traditional vision transformers, our deformable MHSA module preferentially concentrates on spatially pertinent patches through learned offset predictions, markedly diminishing processing demands while improving localized feature representation. DA-ViT contains only More >

Khalil Ibrahim Lairedj¹, Zouaoui Chama¹, Amina Bagdaoui¹, Samia Larguech², Younes Menni^3,4,*, Nidhal Becheikh⁵, Lioua Kolsi^6,*, Badr M. Alshammari⁷

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2419-2443, 2025, DOI:10.32604/cmes.2025.069396 - 31 August 2025

Abstract Brain tumor segmentation from Magnetic Resonance Imaging (MRI) supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans, making it a crucial yet challenging task. Supervised models such as 3D U-Net perform well in this domain, but their accuracy significantly improves with appropriate preprocessing. This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model (GGMM) to T1 contrast-enhanced MRI scans from the BraTS 2020 dataset. The Expectation-Maximization (EM) algorithm is employed to estimate parameters for four tissue classes, generating a More >

Fatma M. Talaat^1,2,*, Mohamed Salem¹, Mohamed Shehata^3,4,*, Warda M. Shaban⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2325-2358, 2025, DOI:10.32604/cmes.2025.067195 - 31 August 2025

Abstract The diagnosis of brain tumors is an extended process that significantly depends on the expertise and skills of radiologists. The rise in patient numbers has substantially elevated the data processing volume, making conventional methods both costly and inefficient. Recently, Artificial Intelligence (AI) has gained prominence for developing automated systems that can accurately diagnose or segment brain tumors in a shorter time frame. Many researchers have examined various algorithms that provide both speed and accuracy in detecting and classifying brain tumors. This paper proposes a new model based on AI, called the Brain Tumor Detection (BTD)… More >

Apoorav Sharma¹, Ayush Dogra^2,*, Bhawna Goyal³, Archana Saini², Vinay Kukreja²

CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 367-481, 2025, DOI:10.32604/cmc.2025.066481 - 29 August 2025

Abstract To enable proper diagnosis of a patient, medical images must demonstrate no presence of noise and artifacts. The major hurdle lies in acquiring these images in such a manner that extraneous variables, causing distortions in the form of noise and artifacts, are kept to a bare minimum. The unexpected change realized during the acquisition process specifically attacks the integrity of the image’s quality, while indirectly attacking the effectiveness of the diagnostic process. It is thus crucial that this is attended to with maximum efficiency at the level of pertinent expertise. The solution to these challenges… More >

Yao-Tien Chen¹, Nisar Ahmad^1,*, Khursheed Aurangzeb²

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 1197-1224, 2025, DOI:10.32604/cmes.2025.066580 - 31 July 2025

Abstract Accurate and efficient brain tumor segmentation is essential for early diagnosis, treatment planning, and clinical decision-making. However, the complex structure of brain anatomy and the heterogeneous nature of tumors present significant challenges for precise anomaly detection. While U-Net-based architectures have demonstrated strong performance in medical image segmentation, there remains room for improvement in feature extraction and localization accuracy. In this study, we propose a novel hybrid model designed to enhance 3D brain tumor segmentation. The architecture incorporates a 3D ResNet encoder known for mitigating the vanishing gradient problem and a 3D U-Net decoder. Additionally, to… More > Graphic Abstract

Rachana Poongodan¹, Dayanand Lal Narayan², Deepika Gadakatte Lokeshwarappa³, Hirald Dwaraka Praveena⁴, Dae-Ki Kang^5,*

CMC-Computers, Materials & Continua, Vol.84, No.3, pp. 5751-5772, 2025, DOI:10.32604/cmc.2025.066314 - 30 July 2025

Abstract In recent decades, brain tumors have emerged as a serious neurological disorder that often leads to death. Hence, Brain Tumor Segmentation (BTS) is significant to enable the visualization, classification, and delineation of tumor regions in Magnetic Resonance Imaging (MRI). However, BTS remains a challenging task because of noise, non-uniform object texture, diverse image content and clustered objects. To address these challenges, a novel model is implemented in this research. The key objective of this research is to improve segmentation accuracy and generalization in BTS by incorporating Switchable Normalization into Faster R-CNN, which effectively captures the… More >

Mohammed Alshahrani¹, Mohammed Al-Jabbar^1,*, Ebrahim Mohammed Senan^2,3, Fatima Ali Amer jid Almahri⁴, Sultan Ahmed Almalki¹, Eman A. Alshari^3,5

CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.3, pp. 3639-3675, 2025, DOI:10.32604/cmes.2025.064668 - 30 June 2025

Abstract Multiple Sclerosis (MS) poses significant health risks. Patients may face neurodegeneration, mobility issues, cognitive decline, and a reduced quality of life. Manual diagnosis by neurologists is prone to limitations, making AI-based classification crucial for early detection. Therefore, automated classification using Artificial Intelligence (AI) techniques has a crucial role in addressing the limitations of manual classification and preventing the development of MS to advanced stages. This study developed hybrid systems integrating XGBoost (eXtreme Gradient Boosting) with multi-CNN (Convolutional Neural Networks) features based on Ant Colony Optimization (ACO) and Maximum Entropy Score-based Selection (MESbS) algorithms for early… More >

Jasem Almotiri^*

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2109-2142, 2025, DOI:10.32604/cmc.2025.062923 - 16 April 2025

Abstract The evolving field of Alzheimer’s disease (AD) diagnosis has greatly benefited from deep learning models for analyzing brain magnetic resonance (MR) images. This study introduces Dynamic GradNet, a novel deep learning model designed to increase diagnostic accuracy and interpretability for multiclass AD classification. Initially, four state-of-the-art convolutional neural network (CNN) architectures, the self-regulated network (RegNet), residual network (ResNet), densely connected convolutional network (DenseNet), and efficient network (EfficientNet), were comprehensively compared via a unified preprocessing pipeline to ensure a fair evaluation. Among these models, EfficientNet consistently demonstrated superior performance in terms of accuracy, precision, recall, and… More >