Walid El-Shafai^1,*, Randa Ali¹, Ahmed Sedik², Taha El-Sayed Taha¹, Mohammed Abd-Elnaby³, Fathi E. Abd El-Samie¹

Intelligent Automation & Soft Computing, Vol.35, No.2, pp. 1843-1856, 2023, DOI:10.32604/iasc.2023.019198

Abstract The use of intelligent machines to work and react like humans is vital in emerging smart cities. Computer-aided analysis of complex and huge MRI (Magnetic Resonance Imaging) scans is very important in healthcare applications. Among AI (Artificial Intelligence) driven healthcare applications, tumor detection is one of the contemporary research fields that have become attractive to researchers. There are several modalities of imaging performed on the brain for the purpose of tumor detection. This paper offers a deep learning approach for detecting brain tumors from MR (Magnetic Resonance) images based on changes in the division of the training and testing data… More >

Xinshan Cao^*, Ling Xu^†, Quanyuan Liu^*, Lijuan Yang^‡, Na Li^§, Xiaoxiao Li^*

Oncology Research, Vol.27, No.3, pp. 301-309, 2019, DOI:10.3727/096504018X15213058045841

Abstract Our study aimed to investigate the roles and possible regulatory mechanism of miR-1277 in the development of hepatocellular carcinoma (HCC). HCC patients were identified from patients who were diagnosed with focal liver lesions using magnetic resonance imaging (MRI). The expression levels of miR-1277 in the serum of HCC patients and HepG2 cells were measured. Then miR-1277 mimic, miR-1277 inhibitor, or scramble RNA was transfected into HepG2 cells. The effects of miR-1277 overexpression and suppression on HepG2 cell proliferation, migration, and invasion were then investigated. Additionally, the expression levels of epithelial– mesenchymal transition (EMT)-related markers, including E-cadherin, -catenin, and vimentin, were… More >

Piao Yongfeng^*†‡§1, Jiang Chuner^*¶#1, Wang Lei^*†‡§, Yan Fengqin^*†‡§, Ye Zhimin^*†‡§, Fu Zhenfu^*†‡§, Jiang Haitao^*,**††, Jiang Yangming^‡‡, Wang Fangzheng^*†‡§

Oncology Research, Vol.28, No.6, pp. 605-613, 2020, DOI:10.3727/096504020X16022401878096

Abstract The aim of this study was to explore the predictive role of pretreatment MRI-based radiomics on early response of neoadjuvant chemotherapy (NAC) in locoregionally advanced nasopharyngeal carcinoma (NPC) patients. Between January 2016 and December 2016, a total of 108 newly diagnosed NPC patients who were hospitalized in the Cancer Hospital of the University of Chinese Academy of Sciences were reviewed. All patients had complete data of enhanced MR of nasopharynx before treatment, and then received two to three cycles of TP-based NAC. After 2 cycles of NAC, enhanced MR of nasopharynx was conducted again. Compared with the enhanced MR images… More >

Abdullah A. Asiri¹, Tariq Ali², Ahmad Shaf², Muhammad Aamir², Muhammad Shoaib³, Muhammad Irfan⁴, Hassan A. Alshamrani^1,*, Fawaz F. Alqahtani¹, Osama M. Alshehri⁵

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 3983-4002, 2022, DOI:10.32604/cmc.2022.030923

Abstract Brain tumor is one of the most dreadful worldwide types of cancer and affects people leading to death. Magnetic resonance imaging methods capture skull images that contain healthy and affected tissue. Radiologists checked the affected tissue in the slice-by-slice manner, which was time-consuming and hectic task. Therefore, auto segmentation of the affected part is needed to facilitate radiologists. Therefore, we have considered a hybrid model that inherits the convolutional neural network (CNN) properties to the support vector machine (SVM) for the auto-segmented brain tumor region. The CNN model is initially used to detect brain tumors, while SVM is integrated to… More >

Irfan Ahmed Usmani^1,*, Muhammad Tahir Qadri¹, Razia Zia¹, Asif Aziz², Farheen Saeed³

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 4369-4392, 2022, DOI:10.32604/cmc.2022.030698

Abstract Knowledge-based transfer learning techniques have shown good performance for brain tumor classification, especially with small datasets. However, to obtain an optimized model for targeted brain tumor classification, it is challenging to select a pre-trained deep learning (DL) model, optimal values of hyperparameters, and optimization algorithm (solver). This paper first presents a brief review of recent literature related to brain tumor classification. Secondly, a robust framework for implementing the transfer learning technique is proposed. In the proposed framework, a Cartesian product matrix is generated to determine the optimal values of the two important hyperparameters: batch size and learning rate. An extensive… More >

Walid El-Shafai^1,2, Amira A. Mahmoud¹, El-Sayed M. El-Rabaie¹, Taha E. Taha¹, Osama F. Zahran¹, Adel S. El-Fishawy¹, Naglaa F. Soliman³, Amel A. Alhussan^4,*, Fathi E. Abd El-Samie¹

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 3119-3135, 2022, DOI:10.32604/cmc.2022.028935

Abstract This paper presents a study of the segmentation of medical images. The paper provides a solid introduction to image enhancement along with image segmentation fundamentals. In the first step, the morphological operations are employed to ensure image detail protection and noise-immunity. The objective of using morphological operations is to remove the defects in the texture of the image. Secondly, the Fuzzy C-Means (FCM) clustering algorithm is used to modify membership function based only on the spatial neighbors instead of the distance between pixels within local spatial neighbors and cluster centers. The proposed technique is very simple to implement and significantly… More >

R. Priyadharsini^*, A. Kunthavai

Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 261-279, 2023, DOI:10.32604/iasc.2023.025884

Abstract Radio waves and strong magnetic fields are used by Magnetic Resonance Imaging (MRI) scanners to detect tumours, wounds and visualize detailed images of the human body. Wi-Fi and other medical devices placed in the MRI procedure room produces RF noise in MRI Images. The RF noise is the result of electromagnetic emissions produced by Wi-Fi and other medical devices that interfere with the operation of the MRI scanner. Existing techniques for RF noise mitigation involve RF shielding techniques which induce eddy currents that affect the MRI image quality. RF shielding techniques are complex and lead to RF leakage. VLC (Visible… More >

K. Chola Raja^1,*, S. Kannimuthu²

Computer Systems Science and Engineering, Vol.44, No.1, pp. 741-755, 2023, DOI:10.32604/csse.2023.025331

Abstract Autism Spectrum Disorder (ASD) requires a precise diagnosis in order to be managed and rehabilitated. Non-invasive neuroimaging methods are disease markers that can be used to help diagnose ASD. The majority of available techniques in the literature use functional magnetic resonance imaging (fMRI) to detect ASD with a small dataset, resulting in high accuracy but low generality. Traditional supervised machine learning classification algorithms such as support vector machines function well with unstructured and semi structured data such as text, images, and videos, but their performance and robustness are restricted by the size of the accompanying training data. Deep learning on… More >

Syed Nauyan Rashid¹, Muhammad Hanif^2,*, Usman Habib², Akhtar Khalil³, Omair Inam⁴, Hafeez Ur Rehman¹

CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 1001-1017, 2022, DOI:10.32604/cmc.2022.023135

Abstract Gliomas are the most aggressive brain tumors caused by the abnormal growth of brain tissues. The life expectancy of patients diagnosed with gliomas decreases exponentially. Most gliomas are diagnosed in later stages, resulting in imminent death. On average, patients do not survive 14 months after diagnosis. The only way to minimize the impact of this inevitable disease is through early diagnosis. The Magnetic Resonance Imaging (MRI) scans, because of their better tissue contrast, are most frequently used to assess the brain tissues. The manual classification of MRI scans takes a reasonable amount of time to classify brain tumors. Besides this,… More >

Yin Liang^1,*, Gaoxu Xu¹, Sadaqat ur Rehman²

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 4645-4661, 2022, DOI:10.32604/cmc.2022.026999

Abstract Whole brain functional connectivity (FC) patterns obtained from resting-state functional magnetic resonance imaging (rs-fMRI) have been widely used in the diagnosis of brain disorders such as autism spectrum disorder (ASD). Recently, an increasing number of studies have focused on employing deep learning techniques to analyze FC patterns for brain disease classification. However, the high dimensionality of the FC features and the interpretation of deep learning results are issues that need to be addressed in the FC-based brain disease classification. In this paper, we proposed a multi-scale attention-based deep neural network (MSA-DNN) model to classify FC patterns for the ASD diagnosis.… More >