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  • Open Access

    ARTICLE

    Hybrid Ensemble and Federated Learning Framework for Privacy-Preserving Cardiovascular MRI Segmentation

    Karim Gasmi1,*, Afrah Alanazi2, Inam Alanazi2, Sahar Almenwer1, Norah Alanazi1, Sarah Almaghrabi3, Samia Yahyaoui4

    CMES-Computer Modeling in Engineering & Sciences, Vol.147, No.3, 2026, DOI:10.32604/cmes.2026.081705 - 30 June 2026

    Abstract Cardiac magnetic resonance imaging (MRI) segmentation is an essential aspect of quantitative cardiovascular analysis, facilitating accurate evaluation of ventricular volumes, myocardial mass, and functional parameters. Deep learning-based segmentation models have shown strong performance on benchmark datasets such as ACDC, but they remain challenging to deploy in real-world multi-centre settings. Data privacy laws make it hard to share data across institutions, and differences in imaging protocols and patient populations mean that data is not always distributed in the same way (non-IID). This can have a big impact on how well models work together and how well… More >

  • Open Access

    ARTICLE

    An Explainability-Aware Transformer Framework for Brain Tumor Segmentation and Classification Using MRI

    Mamoona Jabbar, Uzma Jamil*, Muhammad Younas, Bushra Zafar

    CMES-Computer Modeling in Engineering & Sciences, Vol.147, No.1, 2026, DOI:10.32604/cmes.2026.080241 - 27 April 2026

    Abstract Magnetic Resonance Imaging is one of the most commonly used neuro-oncology imaging modalities, which is a non-invasive mode of imaging and helps in detecting brain abnormalities in an effective way. Earlier researchers have demonstrated that brain tumor segmentation and classification can be effectively performed using deep learning techniques. Existing studies are primarily aimed at increasing prediction accuracy and provide insignificant consideration to model interpretability, limiting their practical application in clinical practice. To address this limitation, this research presents a two-stage explainable deep learning model, which combines transformer-based segmentation with an ensemble classification model that is… More >

  • Open Access

    ARTICLE

    Analysis of risk factors for MRI-invisible prostate cancer—the significance of AGGF1 immunohistochemical detection and PSAD

    Jingcheng Lyu1,2,#, Ruiyu Yue1,2,#, Ye Tian1,2,*, Boyu Yang1,2,*

    Canadian Journal of Urology, Vol.33, No.2, pp. 361-375, 2026, DOI:10.32604/cju.2026.074814 - 20 April 2026

    Abstract Objectives: Patients with a multi-parameter magnetic resonance imaging (mpMRI) prostate imaging report and data system (PI-RADS) score ≤ 3, but with clinically significant prostate cancer (CSPCa) detected by biopsy, are termed MRI-Invisible prostate cancer (MRI(-)PCa). This study aims to explore risk factors for MRI(-)PCa and identify immunohistochemical indicators with predictive significance. Methods: A retrospective analysis was conducted on 376 patients with PI-RADS score ≤ 3 who underwent 24-needle systematic prostate biopsy at Beijing Friendship Hospital, Capital Medical University (January 2015 to October 2025). Clinical data, imaging data, and Angiogenic factor with G and FHA domain… More >

  • Open Access

    ARTICLE

    NeuroTriad-ViT: A Scalable and Interpretable Framework for Multi-Class Brain Tumor Classification via MRI and Knowledge Distillation

    Sultan Kahla1, Zuping Zhang1,*, Majed Alsafyani2, Ahmed Emara3,*, Mohammod Abdullah Bin Hossain4, Abdulwahab Osman Sheikhdon1

    CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.076402 - 09 April 2026

    Abstract The effective diagnosis and treatment planning require the correct classification of the cerebral neoplasia, such as glioma, meningioma, and pituitary tumors. The recent developments in the deep learning field have made a significant contribution to the field of image analysis in medicine; however, Vision Transformers (ViTs) have achieved good results but are computationally complex. This paper presents NeuroTriad-ViT, a proprietary large-scale Vision Transformer of 235 million parameters, which is represented as a high-performance teacher model to classify brain tumors. Knowledge distillation is applied in an attempt to transfer the representations that the teacher learned to… More >

  • Open Access

    EDITORIAL

    Smarter, Not More: The Rationale for Reducing Systematic Cores in the MRI-Targeted Biopsy Era

    Zhihong Lv, Yong Xu, Xingkang Jiang*

    Canadian Journal of Urology, Vol.33, No.1, pp. 1-2, 2026, DOI:10.32604/cju.2026.079600 - 28 February 2026

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Effective Deep Learning Models for the Semantic Segmentation of 3D Human MRI Kidney Images

    Roshni Khedgaonkar1, Pravinkumar Sonsare2, Kavita Singh1, Ayman Altameem3, Hameed R. Farhan4, Salil Bharany5, Ateeq Ur Rehman6,*, Ahmad Almogren7,*

    CMC-Computers, Materials & Continua, Vol.87, No.1, 2026, DOI:10.32604/cmc.2025.072651 - 10 February 2026

    Abstract Recent studies indicate that millions of individuals suffer from renal diseases, with renal carcinoma, a type of kidney cancer, emerging as both a chronic illness and a significant cause of mortality. Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) have become essential tools for diagnosing and assessing kidney disorders. However, accurate analysis of these medical images is critical for detecting and evaluating tumor severity. This study introduces an integrated hybrid framework that combines three complementary deep learning models for kidney tumor segmentation from MRI images. The proposed framework fuses a customized U-Net and Mask R-CNN… More >

  • Open Access

    ARTICLE

    A Parallelized Grey Wolf Optimizer-Based Fuzzy C-Means for Fast and Accurate MRI Segmentation on GPU

    Mohammed Debakla1,*, Ali Mezaghrani1, Khalifa Djemal2, Imane Zouaneb1

    CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-21, 2026, DOI:10.32604/cmc.2025.071927 - 09 December 2025

    Abstract Magnetic Resonance Imaging (MRI) has a pivotal role in medical image analysis, for its ability in supporting disease detection and diagnosis. Fuzzy C-Means (FCM) clustering is widely used for MRI segmentation due to its ability to handle image uncertainty. However, the latter still has countless limitations, including sensitivity to initialization, susceptibility to local optima, and high computational cost. To address these limitations, this study integrates Grey Wolf Optimization (GWO) with FCM to enhance cluster center selection, improving segmentation accuracy and robustness. Moreover, to further refine optimization, Fuzzy Entropy Clustering was utilized for its distinctive features… More >

  • Open Access

    ARTICLE

    SwinHCAD: A Robust Multi-Modality Segmentation Model for Brain Tumors Using Transformer and Channel-Wise Attention

    Seyong Jin1, Muhammad Fayaz2, L. Minh Dang3, Hyoung-Kyu Song3, Hyeonjoon Moon2,*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-23, 2026, DOI:10.32604/cmc.2025.070667 - 10 November 2025

    Abstract Brain tumors require precise segmentation for diagnosis and treatment plans due to their complex morphology and heterogeneous characteristics. While MRI-based automatic brain tumor segmentation technology reduces the burden on medical staff and provides quantitative information, existing methodologies and recent models still struggle to accurately capture and classify the fine boundaries and diverse morphologies of tumors. In order to address these challenges and maximize the performance of brain tumor segmentation, this research introduces a novel SwinUNETR-based model by integrating a new decoder block, the Hierarchical Channel-wise Attention Decoder (HCAD), into a powerful SwinUNETR encoder. The HCAD… More >

  • Open Access

    ARTICLE

    A Hybrid Deep Learning Multi-Class Classification Model for Alzheimer’s Disease Using Enhanced MRI Images

    Ghadah Naif Alwakid*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-25, 2026, DOI:10.32604/cmc.2025.068666 - 10 November 2025

    Abstract Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that significantly affects cognitive function, making early and accurate diagnosis essential. Traditional Deep Learning (DL)-based approaches often struggle with low-contrast MRI images, class imbalance, and suboptimal feature extraction. This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans. Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization (CLAHE) and Enhanced Super-Resolution Generative Adversarial Networks (ESRGAN). A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient (MCC)-based evaluation method into the design.… More >

  • Open Access

    ARTICLE

    A Comprehensive Brain MRI and Neurodevelopmental Dataset in Children with Tetralogy of Fallot

    Yang Xu1,#, Yaqi Zhang2,#, Meijiao Zhu3, Pengcheng Xue4, Siyu Ma1, Di Yu1, Liang Hu1, Yuxi Zhang1, Wei Peng1, Jirong Qi1, Xuyun Wen4, Ming Yang3, Xuming Mo1,2,5,*

    Congenital Heart Disease, Vol.20, No.5, pp. 559-570, 2025, DOI:10.32604/chd.2025.072242 - 30 November 2025

    Abstract Background: The life-course management of children with tetralogy of Fallot (TOF) has focused on demonstrating brain structural alterations, developmental trajectories, and cognition-related changes that unfold over time. Methods: We introduce an magnetic resonance imaging (MRI) dataset comprising TOF children who underwent brain MRI scanning and cross-sectional neurocognitive follow-up. The dataset includes brain three-dimensional T1-weighted imaging (3D-T1WI), three-dimensional T2-weighted imaging (3D-T2WI), and neurodevelopmental evaluations using the Wechsler Preschool and Primary Scale of Intelligence–Fourth Edition (WPPSI-IV). Results: Thirty-one children with TOF (age range: 4–33 months; 18 males) were recruited and completed corrective surgery at the Children’s Hospital of Nanjing More >

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