Abdelhak Rhouma¹, Lobna Hajji-Hedfi^1,*, Nahla Alsayd Bouqellah^2,*, Pravin Babasaheb Khaire³, Samar Dali¹, Omaima Bargougui¹, Amira Khlif¹, Laith Khalil Tawfeeq Al-Ani⁴

Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2857-2881, 2024, DOI:10.32604/phyton.2024.057591 - 30 November 2024

Abstract Beauveria bassiana and Metarhizium spp. are entomopathogenic fungi with potential applications beyond insect pest control, including plant disease suppression, plant growth promotion, and rhizosphere colonization. This study investigated the plant growth-promoting characteristics and extracellular enzyme activities of Metarhizium spp. and B. bassiana in relation to phytopathogen interactions and plant growth. Additionally, the efficacy of these fungi in mitigating damping-off and root rot caused by Rhizoctonia solani on cucumber plants was evaluated in vitro and in vivo. Results indicate that B. bassiana and M. anisopliae produce indole-3-acetic acid, hydrocyanic acid, and hydrolytic enzymes. Seed treatment with these fungi significantly reduced disease severity (3.85%–1.86%, respectively)… More >

Ahmed Mahmoud Ismail^1,2,3,*, Eman Said Elshewy³, Isra H. Ali^4,5, Naglaa Abd Elbaki Sallam Muhanna³, Eman Yehia Khafagi³

Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2787-2811, 2024, DOI:10.32604/phyton.2024.057518 - 30 November 2024

Abstract Rhizoctonia solani Kühn and Sclerotium rolfsii Sacc. are the primary soil-borne plant diseases responsible for significant reductions in global crop yields. The primary goal of this study was to investigate the antifungal potentials of clove essential oil (CEO), nanoemulsion form (CEONE) and chitosan/nanoemulsion nanocomposite (CS/CEONE) against R. solani and S. rolfsii through in vitro and in vivo trials. Both CEONE and CS/CEONE were prepared and investigated for their physical chemical and morphological characterization. The poisoned medium method was utilized to evaluate the inhibitory effects of CEO, CEONE and CS/CEONE on the mycelial growth and enzymatic activity of R. solani and S. rolfsii. The… More >

Yiyuan Li¹, Yongjing Li^1,2, Shilin Yan^1,2,*, Pin Wen^1,2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 3105-3119, 2024, DOI:10.32604/cmes.2024.051375 - 08 July 2024

Abstract Based on the traditional re-entrant honeycomb, a novel re-entrant octagon honeycomb (ROH) is proposed. The deformation mode of the honeycomb under quasi-static compression is analyzed by numerical simulation, and the results are in good agreement with the experimental ones. The deformation modes, mechanical properties, and energy absorption characteristics of ROH along the impact and perpendicular directions gradient design are investigated under different velocities. The results indicated that the deformation mode of ROH is affected by gradient design along the direction of impact and impact speed. In addition, gradient design along the direction of impact can… More >

Xu Xu¹, Xiaoteng Wang¹, Haitian Yang¹, Zhenjun Yang², Yiqian He^1,3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1831-1861, 2024, DOI:10.32604/cmes.2024.048199 - 20 May 2024

Abstract The multiscale method provides an effective approach for the numerical analysis of heterogeneous viscoelastic materials by reducing the degree of freedoms (DOFs). A basic framework of the Multiscale Scaled Boundary Finite Element Method (MsSBFEM) was presented in our previous works, but those works only addressed two-dimensional problems. In order to solve more realistic problems, a three-dimensional MsSBFEM is further developed in this article. In the proposed method, the octree SBFEM is used to deal with the three-dimensional calculation for numerical base functions to bridge small and large scales, the three-dimensional image-based analysis can be conveniently… More >

Jialun Lin¹, Qiong Chen^1,2,3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.2, pp. 1549-1561, 2024, DOI:10.32604/cmes.2023.029631 - 17 November 2023

Abstract Watermarks can provide reliable and secure copyright protection for optical coherence tomography (OCT) fundus images. The effective image segmentation is helpful for promoting OCT image watermarking. However, OCT images have a large amount of low-quality data, which seriously affects the performance of segmentation methods. Therefore, this paper proposes an effective segmentation method for OCT fundus image watermarking using a rough convolutional neural network (RCNN). First, the rough-set-based feature discretization module is designed to preprocess the input data. Second, a dual attention mechanism for feature channels and spatial regions in the CNN is added to enable… More >

Arjun Pon Avudaiappan¹, Pushan Prabhakar¹, Hariharan Ganapathi², Nathan VanderVeer-Harris³, Jorge Caso^1,3, Rohan Garje¹, Murugesan Manoharan^1,3

Canadian Journal of Urology, Vol.30, No.5, pp. 11686-11691, 2023

Abstract Introduction: Radical cystectomy (RC) is an effective curative treatment option for muscle-invasive bladder cancer (MIBC). However, chemoradiation (CRT) is an evolving bladder preservation protocol alternative to RC. With the increase in life expectancy, it is essential to understand the survival outcomes among octogenarians treated with RC and CRT. In this study, we use the National Cancer Database (NCDB) to compare the survival outcomes between RC and CRT in octogenarians.
Materials and methods: We collected the data of patients treated for bladder cancer between 2004 to 2018 from the NCDB. Our primary analytic cohort included patients with MIBC… More >

Sayyid Kamran Hussain¹, Ali Haider Khan^2,*, Malek Alrashidi³, Sajid Iqbal⁴, Qazi Mudassar Ilyas⁴, Kamran Shah⁵

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3763-3781, 2023, DOI:10.32604/cmc.2023.041722 - 08 October 2023

Abstract As ocular computer-aided diagnostic (CAD) tools become more widely accessible, many researchers are developing deep learning (DL) methods to aid in ocular disease (OHD) diagnosis. Common eye diseases like cataracts (CATR), glaucoma (GLU), and age-related macular degeneration (AMD) are the focus of this study, which uses DL to examine their identification. Data imbalance and outliers are widespread in fundus images, which can make it difficult to apply many DL algorithms to accomplish this analytical assignment. The creation of effcient and reliable DL algorithms is seen to be the key to further enhancing detection performance. Using… More >

LINGYAN LV^1,2,#, JING ZHAO^1,2,#, XUAN WANG^1,2, LIUYAN XU^1,2, YINGYI FAN², CHUNHUI WANG³, HONGQIAO FAN^4,5,*, XIAOHUA PEI^5,*

BIOCELL, Vol.47, No.9, pp. 1977-1994, 2023, DOI:10.32604/biocell.2023.030742 - 28 September 2023

Abstract Background: The development and prognosis of breast cancer are intricately linked to psychological stress. In addition, depression is the most common psychological comorbidity among breast cancer survivors, and reportedly, Fang-Xia-Dihuang decoction (FXDH) can effectively manage depression in such patients. However, its pharmacological and molecular mechanisms remain obscure. Methods: Public databases were used for obtaining active components and related targets. Main active components were further verified by ultra-high-performance liquid chromatography-high-resolution mass spectrometry (UPLC-HRMS). Protein–protein interaction and enrichment analyses were taken to predict potential hub targets and related pathways. Molecule docking was used to understand the interactions… More >

SHIMING YE^1,2,#, YUFENG ZHANG^3,#, TING LIU⁴, CONG WANG³, ZHENG YAN⁵, WANDONG SHE^2,*, HAIBING HUA^4,*

BIOCELL, Vol.47, No.9, pp. 1947-1964, 2023, DOI:10.32604/biocell.2023.029333 - 28 September 2023

Abstract Background: Despite its widespread therapeutic use and effectiveness, the underlying pharmacologic mechanisms of Wendan decoction (WDD) and how it works to treat sudden deafness (SD) remain unclear. In this study, the pharmacological mechanisms of WDD underlying SD were analyzed using network pharmacology and molecular docking. Methods: The Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) was employed to identify the active compounds and target genes of WDD, and genes associated with SD were screened on five databases. RGUI conducted Gene Ontology (GO) functional and the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses. A… More >

CHENHAO SHI¹, MAOHONG HUA², GUANHUA XU^3,*

BIOCELL, Vol.47, No.6, pp. 1329-1344, 2023, DOI:10.32604/biocell.2023.028381 - 19 May 2023

Abstract Background: Ulcerative colitis (UC) is a chronic disease that often presents with abdominal pain, diarrhea, hematochezia, and significant morbidity. Gancao Xiexin decoction (GXD), a traditional Chinese medicine, has been applied for the clinical treatment of UC, while its action mechanisms are unclear. Methods: The active ingredients and their targets of GXD, and UC-related targets, were derived from public databases. Protein-protein interaction, Gene Ontology (GO), and the Kyoto Encyclopedia of Genes and Genomes (KEGG) were used to analyze the important active compounds, key targets, and signaling pathways. Then, molecular docking and animal experiments were performed to verify… More >