Wenjun Hu, Liquan Zhang^*

Journal of Polymer Materials, Vol.42, No.4, pp. 1159-1179, 2025, DOI:10.32604/jpm.2025.072450 - 26 December 2025

Abstract Addressing the persistent challenge of shale hydration and swelling in water-based drilling fluids (WBDFs), this study developed a smart thermo-responsive shale inhibitor, Hyperbranched Polyethyleneimine-Propylene Oxide-N-isopropylacrylamide (HPN). It was synthesized by grafting hyperbranched polyethyleneimine (HPEI) with propylene oxide (PO) and N-isopropylacrylamide (NIPAM), creating a synergistic hydration barrier through hydrophobic association and temperature-triggered pore plugging. Structural characterization by Fourier-Transform Infrared (FTIR) spectroscopy and gel permeation chromatography (GPC) confirmed the successful formation of the HPN terpolymer, revealing a unique “cationic–nonionic” amphiphilic architecture with temperature-responsive properties. Performance evaluation demonstrated that HPN significantly outperforms conventional inhibitors, including potassium chloride (KCl),… More >

Dong Hwan Ho^1,*, Minhyung Lee^2,3, Daleum Nam¹, Hyejung Kim¹, Janghwan Kim^2,3, Mi Kyoung Seo^4,5, Sung Woo Park^4,5, Ilhong Son^1,6,*

BIOCELL, Vol.49, No.7, pp. 1225-1244, 2025, DOI:10.32604/biocell.2025.065486 - 25 July 2025

Abstract Background: Parkinson’s disease (PD) is a common neurodegenerative disease, characterized by symptoms like tremors, muscle rigidity, and slow movement. The main cause of these symptoms is the loss of dopamine-producing neurons in a brain area called the substantia nigra. Various genetic and environmental factors contribute to this neuronal loss. Once symptoms of PD begin, they worsen with age, which also impacts several critical cellular processes. Leucine-rich repeat kinase 2 (LRRK2) is a gene associated with PD. Certain mutations in LRRK2, such as G2019S, increase its activity, disrupting cellular mechanisms necessary for healthy neuron function, including… More >

Yiqin He^1,2, Chenhan Hu^1,2, Xiangshu Meng^1,2, Rundong Ma^1,2, Kexin Duan^1,2, Yu Guo^2,3, Changqing Liu^1,2, Caiyun Ma^1,2, Gaofeng Liu^1,2,*, Chunjing Wang^1,2,*

BIOCELL, Vol.49, No.6, pp. 1037-1055, 2025, DOI:10.32604/biocell.2025.064633 - 24 June 2025

Abstract Background: Mesenchymal stem cells (MSCs) have shown great potential in treating neurodegenerative diseases, including Parkinson’s disease (PD), due to their ability to differentiate into neurons and secrete neurotrophic factors. Genetic modification of MSCs for PD treatment has become a research focus. Methods: In this study, rat pulmonary mesenchymal stem cells (PMSCs) were transduced with lentiviral vectors carrying Lmx1a/NeuroD1 to establish genetically engineered PMSCs (LN-PMSCs) and induce their differentiation into dopaminergic neurons. The LN-PMSCs were then transplanted into the right medial forebrain bundle region of PD model rats prepared using the 6-Hydroxydopamine (6-OHDA) method. Four weeks… More >

Jinliang Luo, Dongliang Li, Yang Li, Miaojiao Wang, Xiaomin Kang, Zhitao Hu^*

Journal of Polymer Materials, Vol.42, No.1, pp. 125-140, 2025, DOI:10.32604/jpm.2024.059636 - 27 March 2025

Abstract With the rapid development of flexible wearable electronic products, their application fields and demands are increasing, posing new challenges to flexible conductive materials. This paper selected flexible polydimethylsiloxane (PDMS) as the substrate. In order to enhance the adhesion between the substrate and the metal coating, dopamine and silanization were used to co-modify its surface. A conductive layer of metallic copper is deposited on its surface using an inexpensive, easy-to-use electroless plating technique. By optimizing the process conditions, it is found that a uniform copper layer of about 0.6 μm can be formed on the surface More >

Tawfeeq Shawly¹, Ahmed A. Alsheikhy^2,*, Yahia Said³, Shaaban M. Shaaban³, Husam Lahza⁴, Aws I. AbuEid⁵, Abdulrahman Alzahrani⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.3, pp. 3181-3212, 2025, DOI:10.32604/cmes.2025.061608 - 03 March 2025

Abstract Email communication plays a crucial role in both personal and professional contexts; however, it is frequently compromised by the ongoing challenge of spam, which detracts from productivity and introduces considerable security risks. Current spam detection techniques often struggle to keep pace with the evolving tactics employed by spammers, resulting in user dissatisfaction and potential data breaches. To address this issue, we introduce the Divide and Conquer-Generative Adversarial Network Squeeze and Excitation-Based Framework (DaC-GANSAEBF), an innovative deep-learning model designed to identify spam emails. This framework incorporates cutting-edge technologies, such as Generative Adversarial Networks (GAN), Squeeze and… More >

Y. L. Hou^*, L. Z Bai

Chalcogenide Letters, Vol.21, No.10, pp. 785-796, 2024, DOI:10.15251/CL.2024.2110.785

Abstract This study investigated the development of a novel composite modified asphalt incorporating PDA-MoS₂ into styrene-butadiene-styrene (SBS) modified asphalt. The successful synthesis of PDA-MoS₂ was confirmed through various characterization techniques. The incorporation of PDA-MoS₂ into SBS modified asphalt resulted in significant improvements in performance properties. With a PDA-MoS₂ content of 0.7 wt%, the modified asphalt showed a notable 15.1% rise in softening point and a 24% drop in penetration in comparison to the control SBS modified asphalt. Dynamic Shear Rheometer tests revealed a 2.4-fold increase in the rutting factor at 60°C. Multiple Stress Creep Recovery tests demonstrated enhanced… More >

Xianzhi Chen¹, Dong Niu^1,*, Hongtao Gao¹, Mu Du^2,3,*

Frontiers in Heat and Mass Transfer, Vol.22, No.6, pp. 1743-1760, 2024, DOI:10.32604/fhmt.2024.058274 - 19 December 2024

Abstract Thermosensitive hydrogel can integrate vapor molecular capture, in-situ liquefaction, and thermal-induced water release for freshwater capture. This study aimed to examine the dynamic behavior of poly (N-isopropylacrylamide) (PNIPAM) single chain and cross-linking thermosensitive hydrogel through molecular dynamics simulation. Specifically, the impact of lower critical solution temperature (LCST) on the conformation of polymer chain and the interaction between water and polymer chain were also investigated. The polymer chain conformation underwent a transition from coil to globule when the temperature exceeded the LCST, indicating the temperature responsiveness of PNIPAM. Additionally, thermosensitive hydrogel samples with different cross-linking degrees (DOC) More > Graphic Abstract

MOHAMMAD-SADEGH LOTFI, FATEMEH B. RASSOULI^*

BIOCELL, Vol.48, No.10, pp. 1419-1428, 2024, DOI:10.32604/biocell.2024.053597 - 02 October 2024

Abstract Parkinson’s disease (PD) is one of the fastest-growing neurodegenerative disorders worldwide. So far, PD treatments only offer little clinical relief and cannot reverse or stop the disease progression. Stem cell (SC) therapy is a rapidly evolving technology that holds significant promise for enhancing current therapeutic approaches. Adipose-derived mesenchymal SCs (AD-MSCs) have many features such as easy harvest with minimal invasive techniques, high plasticity, non-immunogenicity, and no ethical issues, which have made them suitable choices for clinical applications in regenerative research. AD-MSCs are ideal tools to treat PD, as they have the potential to differentiate into… More >

Hussein Alaa Al-Kabbi^1,2, Mohammad-Reza Feizi-Derakhshi^1,*, Saeed Pashazadeh³

Intelligent Automation & Soft Computing, Vol.39, No.4, pp. 665-682, 2024, DOI:10.32604/iasc.2024.050452 - 06 September 2024

Abstract SMS spam poses a significant challenge to maintaining user privacy and security. Recently, spammers have employed fraudulent writing styles to bypass spam detection systems. This paper introduces a novel two-level detection system that utilizes deep learning techniques for effective spam identification to address the challenge of sophisticated SMS spam. The system comprises five steps, beginning with the preprocessing of SMS data. RoBERTa word embedding is then applied to convert text into a numerical format for deep learning analysis. Feature extraction is performed using a Convolutional Neural Network (CNN) for word-level analysis and a Bidirectional Long… More >

Ana Elena de Villalobos^1,2,*, María Andrea Long^1,2

Phyton-International Journal of Experimental Botany, Vol.93, No.8, pp. 2037-2050, 2024, DOI:10.32604/phyton.2024.053928 - 30 August 2024

Abstract Livestock grazing has a significant impact on natural grasslands, with approximately one-third of the world’s land area dedicated to this industry. Around 20% of global grasslands are highly degraded due to overgrazing, affecting their productivity and conservation capacity. Best practices are required to ensure sustainable livestock production that supports biodiversity. The Intermediate Disturbance Hypothesis (IDH) suggests that environments with moderate levels of disturbance exhibit a higher species diversity. Moderate grazing can reduce the dominance of certain species, thereby enhancing plant diversity. However, concerns arise regarding the increase of exotic and unpalatable species under moderate grazing… More >