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  • Open Access

    ARTICLE

    Construction of an International Digital Sharing Platform of Dongba Manuscripts and Dongba Hieroglyphs

    Xu Xiaoli1,∗, Li Dong1, Jiang Zhanglei1, Li Ning1, Wu Guoxin1, Wang Hongjun1, Zhang Xu2, Bai Feng2

    Computer Systems Science and Engineering, Vol.34, No.4, pp. 191-199, 2019, DOI:10.32604/csse.2019.34.191

    Abstract With the aim of protecting, bequeathing, and sharing globally the Dongba manuscripts of the Chinese Naxi minority, the memory and heritage of which is under threat, this paper proposes ideas and plans for building a digital sharing platform to fulfil this aim using computer technology, information processing, online dissemination, multimedia display and other technologies to build an international digital platform for the sharing of Dongba manuscripts. This platform provides digital resources comprising Dongba manuscripts and related literature, tools for deciphering Dongba manuscripts, an environment for undertaking and sharing research, and dynamic information on the research findings and inheritance. The platform… More >

  • Open Access

    ARTICLE

    Enhancing Embedding-Based Chinese Word Similarity Evaluation with Concepts and Synonyms Knowledge

    Fulian Yin, Yanyan Wang, Jianbo Liu*, Meiqi Ji

    CMES-Computer Modeling in Engineering & Sciences, Vol.124, No.2, pp. 747-764, 2020, DOI:10.32604/cmes.2020.010579

    Abstract Word similarity (WS) is a fundamental and critical task in natural language processing. Existing approaches to WS are mainly to calculate the similarity or relatedness of word pairs based on word embedding obtained by massive and high-quality corpus. However, it may suffer from poor performance for insuf- ficient corpus in some specific fields, and cannot capture rich semantic and sentimental information. To address these above problems, we propose an enhancing embedding-based word similarity evaluation with character-word concepts and synonyms knowledge, namely EWS-CS model, which can provide extra semantic information to enhance word similarity evaluation. The core of our approach contains… More >

  • Open Access

    REVIEW

    Mechanisms of the Formation and Involuntary Repetition of Trauma-Related Flashback: A Review of Major Theories of PTSD

    Ming Wang1, Jing Liu2,*, Qiwu Sun3,4, Wenzhen Zhu4

    International Journal of Mental Health Promotion, Vol.21, No.3, pp. 81-97, 2019, DOI:10.32604/IJMHP.2019.011010

    Abstract Trauma-related flashback is one of the typical symptoms of patients suffered from posttraumatic stress disorder (PTSD), which intrudes into the body and mind of patients uncontrobaly and repeatedly. Psychodynamic theories of mechanisms of the formation and involuntary repetition of trauma-related flashback establish a foundation for most cognitive theories of PTSD. Cognitive behavioral theories of PTSD, from the initial use of behavioristic principles (e.g., conditioning, alternative learning, generalization, etc.) to explain fear conditioning to the emphasis on the roles of cognitive and behavioral factors (e.g., cognitive model or schema, completion tendency, associative network, data-driven processing, analogue representation, etc.) in the representation… More >

  • Open Access

    REVIEW

    Cognitive Intervention on the Flashback of Traumatic Event: Based on the Dual Representation Theory of PTSD

    Jing Liu1, Xuelian Chen1,*, Ming Wang2, Lin Cheng3

    International Journal of Mental Health Promotion, Vol.20, No.3, pp. 75-82, 2018, DOI:10.32604/IJMHP.2018.010857

    Abstract Flashback, related to the traumatic event, is a prominent symptom of posttraumatic stress disorder (PTSD). The dual representation theory (DRT) of PTSD emphasizes that the weakened contextual representation (C-rep), the enhanced sensory representation (S-rep) and the loss of connection between C-rep and S-rep play an important role in the formation and retrieval of flashback. DRT proposes that cognitive intervention tasks which inhibit S-rep or enhance C-rep can reduce flashbacks. And many studies have proved this theoretical hypothesis. In the future, simulation intervention studies should continue to strengthen, some clinical application studies should also be appropriately carried out. Besides, future researchers… More >

  • Open Access

    ARTICLE

    Knockdown of apoptosis-inducing factor disrupts function of respiratory complex

    MIROSLAV VAŘECHA1*, DANIELA PÁCLOVÁ2, JIŘINA PROCHÁZKOVÁ2, PAVEL MATULA1, DUŠAN CMARKO3, AND MICHAL KOZUBEK1

    BIOCELL, Vol.36, No.3, pp. 121-126, 2012, DOI:10.32604/biocell.2012.36.121

    Abstract Recent findings suggest that apoptotic protein apoptosis-inducing factor (AIF) may also play an important non-apoptotic function inside mitochondria. AIF was proposed to be an important component of respiratory chain complex I that is the major producer of superoxide radical. The possible role of AIF is still controversial. Superoxide production could be used as a valuable measure of complex I function, because the majority of superoxide is produced there. Therefore, we employed superoxide-specific mitochondrial fluorescence dye for detection of superoxide production. We studied an impact of AIF knockdown on function of mitochondrial complex I by analyzing superoxide production in selected cell… More >

  • Open Access

    ARTICLE

    Isolation of epithelial cells, villi and crypts from small intestine of pigeons (Columba livia)

    OSCAR MAC DONAL1, JUAN G. CHEDIACK1,2,3, ENRIQUE CAVIEDES-VIDAL1,2,3

    BIOCELL, Vol.32, No.3, pp. 219-227, 2008, DOI:10.32604/biocell.2008.32.219

    Abstract The isolation of viable enterocytes, villi and crypts from the small intestine of a feral bird (Columba livia) is important for performing physiological experiments in ecologically relevant processes of membrane transport. The effectiveness of mechanical disruption, enzymatic digestion and chelating agents were compared. The objectives were to isolate enterocytes, villi and crypts from the small intestine of young pigeons; to evaluate the viability of the isolated intestinal epithelial cells isolated; and to verify the integrity of enterocytes by biochemical features. Enzymatic and mechanical methods yielded both elongated columnar and spherical cells. With the chelating method villi and crypts were obtained.… More >

  • Open Access

    ABSTRACT

    Fast Force Loading Disrupts Molecular Bond Stability in Human and Mouse Cell Adhesions

    Yunfeng Chen1,2,3,†,*, Jiexi Liao4,†, Zhou Yuan1, Kaitao Li4, Baoyu Liu4, Lining Arnold Ju4,5,6, Cheng Zhu1,2,4,5,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 97-97, 2019, DOI:10.32604/mcb.2019.07123

    Abstract Force-mediated molecular binding initiates numerous cellular activities such as cell adhesion, migration, and activation. Dynamic force spectroscopy (DFS) is widely used to examine molecular binding and cell mechano-signaling [1]. The rate of dissociation, off-rate, is an important attribute of molecular binding that reflects bond stability. Extensive DFS works have demonstrated that off-rates are a function of force magnitude, yielding signature bond behaviors like “catch bond” [2]. However, as a controversial topic of the field, different DFS assays, i.e., force-clamp and force-ramp assays, often yielded distinctive "off-rate vs. force" relations from the same molecular system [3]. Such discrepancies cast doubt on… More >

  • Open Access

    ARTICLE

    Advanced Design Concepts and Maintenance by Integrated Risk Evaluation for Aerostructures

    R. Citarella1, A. Apicella2

    Structural Durability & Health Monitoring, Vol.2, No.3, pp. 183-196, 2006, DOI:10.3970/sdhm.2006.002.183

    Abstract This paper presents an overview of the achievements of a research and development project sponsored by the European Commission in the general area of Key Actions and New Perspectives in Aeronautics. The project was coordinated by Alenia and involved partners from major European Aircraft and Helicopter manufactures as well as research institutions and universities. The project was in support of EU policies on energy and environment, in addition to those on transport, economic and social cohesion, industry and, of course, research and technology.
    The overall objective of Advanced Design concepts and Maintenance by Integrated risk Evaluation for aerostructures (ADMIRE) was… More >

  • Open Access

    ABSTRACT

    Minireview : Old Species and New Concepts in The Taxonomy of Pomacea (Gastropoda: Ampullariidae)

    NÉSTOR J. CAZZANIGA

    BIOCELL, Vol.26, Suppl.S, pp. 71-81, 2002

    Abstract The taxonomic history of the South American genus Pomacea Perry, 1810, and some shifts of systematic concepts during recent decades are briefly reviewed. Too many pre-evolutionist, shell-defined species created a gibberish, the only acceptable solution of which being perhaps a conventional, somewhat authoritarian decision based on expertise. The addition of other sources of morphological, biochemical, ecological or genetic information should not solve the problem if it is not accompanied by a sound reappraisal of the species concepts. Since the assumptions of each concept differ, any correspondence between them is irrelevant, and may drive to incompatible results. The shell variability of… More >

  • Open Access

    REVIEW

    Adipose-derived mesenchymal stem/stromal cells: from the lab bench to the basic concepts for clinical translation

    Yesica Romina FRONTINI-LÓPEZ1, Aldana Daniela GOJANOVICH1, Diego MASONE1,2, Diego Martín BUSTOS1,3, Marina UHART1

    BIOCELL, Vol.42, No.3, pp. 67-78, 2018, DOI:10.32604/biocell.2018.07013

    Abstract In the last years, much work has shown that the most effective repair system of the body is represented by stem cells, which are defined as undifferentiated precursors that own unlimited or prolonged self-renewal ability, which also have the potential to transform themselves into various cell types through differentiation.All tissues that form the body contain many different types of somatic cells, along with stem cells that are called ‘mesenchymal stem (or stromal) cells’ (MSC). In certain circumstances, some of these MSC migrate to injured tissues to replace dead cells or to undergo differentiation to repair it.The discovery of MSC has… More >

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