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  • Open Access

    REVIEW

    Bacterial endotoxins in periodontal health and diseases

    FARIHA NUSRAT1, MOHAMMAD TARIQUR RAHMAN2, MUHAMMAD MANJURUL KARIM3,*

    BIOCELL, Vol.47, No.1, pp. 81-89, 2023, DOI:10.32604/biocell.2023.024635

    Abstract Bacterial endotoxins are a major concern in periodontal health and diseases owing to their structure and biological activity. With up-to-date knowledge of endotoxins and the recent findings about the influence of endotoxins in dental health, their probable mode of pathogenesis, and standard detection methods, this review analyzes the potential efficacy and benefits of probiotics in combination with conventional and contemporary treatment measures. In the oral cavity, Gram-negative bacteria are documented to predominate in the pulpal lesions with radiolucent areas and in the root canal with pulp necrosis, where they pose an absolute threat by promoting a series of inflammatory reactions.… More >

  • Open Access

    REVIEW

    Review on microbial metabolomics of probiotics and pathogens: Methodologies and applications

    XIN MENG*, XUE LI, LIANRONG YANG, RUI YIN, LEHUI QI, QI GUO

    BIOCELL, Vol.47, No.1, pp. 91-107, 2023, DOI:10.32604/biocell.2023.024310

    Abstract In recent years, microbial metabolomics, a new field that has attracted wide attention, provides a map of metabolic pathways and clarifies the interaction mechanism between microorganisms and hosts. Many microorganisms are found in the human intestine, oral cavity, vagina, etc. Probiotics could maintain the good health of the host, while pathogens and an imbalance of bacterial flora lead to a series of diseases of the body and mind. Metabolomics is a science for qualitative and quantitative analysis of all metabolites in an organism or biological system, which could provide key information to understand the related metabolic pathways and associated changes.… More >

  • Open Access

    ARTICLE

    Probiotics enhance the recovery of gut atrophy in experimental malnutrition

    DIANA B. DOCK*, JOSÉ E. AGUILAR-NASCIMENTO**, MARCIA Q. LATORRACA*

    BIOCELL, Vol.28, No.2, pp. 143-150, 2004, DOI:10.32604/biocell.2004.28.143

    Abstract AIM: The aim of this study was to evaluate the effect of probiotics on the recovery of the bowel atrophy induced by malnutrition in rats. METHODS: Twenty-and-six Wistar rats (200-250g) were fed with either a normoproteic (sham group, n=6) or a free-protein diet (n=20) during 12 days. Twelve malnourished rats were randomized to recover during 15 days with either a hydrolyzed diet (control group, n=6) or the same diet enriched with probiotics (Streptococcus thermophilus and Lactobacillus helveticus; probiotic group, n=6). RESULTS: Probiotic group showed similar gain of body, liver and bowel weight than controls. At the jejunum, both the villus… More >

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