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  • Open Access

    ARTICLE

    Bioactive Potential of Calophyllum inophyllum: Phytochemical Profiles, Biological Activities, and In Silico Pharmacokinetic Predictions

    Luksamee Vittaya1,*, Chakhriya Chalad1, Sittichoke Janyong2, Nararak Leesakul3

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4091-4115, 2025, DOI:10.32604/phyton.2025.074891 - 29 December 2025

    Abstract Calophyllum inophyllum is a tropical plant that could have useful medicinal properties for pharmaceutical and cosmetic applications. The present study extracted the flower, fruit, leaf, twig, and bark of the plant by maceration in different organic solvents. The correlation between bioactive compounds and their biological activities was investigated, with emphasis on their therapeutic relevance through in silico pharmacokinetic predictions using SwissADME. Qualitative and quantitative analyses were conducted to determine the total phenolic, flavonoid, and saponin contents of the extracts. Spectral analysis of the extracts revealed –OH, C=O, C=C, and C–H functional groups. The antioxidant activity of the… More > Graphic Abstract

    Bioactive Potential of <i>Calophyllum inophyllum</i>: Phytochemical Profiles, Biological Activities, and <i>In Silico</i> Pharmacokinetic Predictions

  • Open Access

    ARTICLE

    Chitosan-Selenate Complex Improves Bioactive Profile and Antioxidant Response in Wheat Sprouts (Triticum aestivum L.)

    Jazmín Montserrat Gaucin-Delgado1, Cristian Oswaldo Solis-López2, Pablo Preciado-Rangel3, Bernardo Espinosa-Palomeque4, Francisco Gerardo Veliz-Deras2, Viridiana Contreras-Villarreal2, Ricardo Israel Ramírez-Gottfried5,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3961-3973, 2025, DOI:10.32604/phyton.2025.072536 - 29 December 2025

    Abstract Selenium (Se) deficiency is a global health problem affecting more than 500 million people; crop biofortification is a sustainable strategy for its mitigation. This study investigated the effect of the application of selenate nanoparticles (SeO42−) and the combination of selenate (SeO42−) and chitosan (CS) (forming a SeO42−-CS complex) on the antioxidant profile, growth, biomass, bioactive compounds, enzymes, and Se accumulation of wheat (Triticum spp.) sprouts. Fourteen treatments were applied using a factorial design combining seven concentrations and two formulations: SeO42− and SeO42−-CS. It was identified that chitosan increased Se uptake efficiency by 30% versus conventional selenate. The optimal… More >

  • Open Access

    ARTICLE

    Customer-employee exchange work through psychological safety and self-efficacy for improved hotel employees’ work engagement

    Fan Deng*

    Journal of Psychology in Africa, Vol.35, No.6, pp. 797-805, 2025, DOI:10.32604/jpa.2025.068735 - 30 December 2025

    Abstract This study investigated the relationship between customer-employee exchange (CEX) and employee work engagement (vigor, dedication, absorption), and the role of psychological safety and self-efficacy mediate that relationship. Survey data were collected from 329 Chinese hotel employees (females = 52.9%, tenure: 1–3 years = 50.5%). The results following ordinary least squares regression and the SPSS PROCESS macro indicate that higher customer-employee exchange is associated with employee vigor, dedication, and absorption. Psychological safety and self-efficacy mediate the relationship between customer-employee exchange and vigor and dedication to be stronger, while the work absorption mediating effect is not significant. More >

  • Open Access

    ARTICLE

    Engineering Amorphous Solid Dispersions of Abiraterone Acetate via HPMC HME: A Polymer-Centric Hot-Melt Extrusion Strategy for Formulation-Driven Bioavailability Improvement

    Manisha Choudhari1, Shantanu Damle2, Rajat Vashist1, Ranendra Narayan Saha3, Sunil Kumar Dubey4, Gautam Singhvi1,*

    Journal of Polymer Materials, Vol.42, No.4, pp. 1199-1229, 2025, DOI:10.32604/jpm.2025.072987 - 26 December 2025

    Abstract Abiraterone acetate (ABTA) was approved by the USFDA in 2011 for treating metastatic castration-resistant prostate cancer (mCRPC). ABTA exhibits poor aqueous solubility, inadequate dissolution, low oral bioavailability (<10%), and significant positive food effects. To overcome these limitations, in the present work, ABTA solid dispersions (SDs) were developed by using hot melt extrusion technology (HME) with various grades of hydroxypropyl methylcellulose HME (HPMC HME 15LV and 100LV) at different extrusion temperatures. HPMC HME demonstrated the ability to prevent drug precipitation for up to 120 min compared to the free drug (10 min), sustaining the supersaturation state… More > Graphic Abstract

    Engineering Amorphous Solid Dispersions of Abiraterone Acetate via HPMC HME: A Polymer-Centric Hot-Melt Extrusion Strategy for Formulation-Driven Bioavailability Improvement

  • Open Access

    ARTICLE

    Optimizing Performance Prediction of Perovskite Photovoltaic Materials by Statistical Methods-Intelligent Calculation Model

    Guo-Feng Fan1,2, Jia-Jing Qian1, Li-Ling Peng1, Xin-Hang Jia1, Ling-Han Zuo1, Jia-Can Yan1, Jiang-Yan Chen1, Anantkumar J. Umbarkar3, Wei-Chiang Hong4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3813-3837, 2025, DOI:10.32604/cmes.2025.073615 - 23 December 2025

    Abstract Accurate prediction of perovskite photovoltaic materials’ optoelectronic properties is crucial for developing efficient and stable materials, advancing solar technology. To address poor interpretability, high computational complexity, and inaccurate predictions in relevant machine learning models, this paper proposes a novel methodology. The technical route of this paper mainly centers on the random forest-knowledge distillation-bidirectional gated recurrent unit with attention technology (namely RF-KD-BIGRUA), which is applied in perovskite photovoltaic materials. Primarily, it combines random forest to quantitatively assess feature importance, selecting variables with significant impacts on photoelectric conversion efficiency. Subsequently, statistical techniques analyze the weight distribution of More >

  • Open Access

    REVIEW

    Advances in the Improved Element-Free Galerkin Methods: A Comprehensive Review

    Heng Cheng1, Yichen Yang1, Yumin Cheng2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 2853-2894, 2025, DOI:10.32604/cmes.2025.073178 - 23 December 2025

    Abstract The element-free Galerkin (EFG) method, which constructs shape functions via moving least squares (MLS) approximation, represents a fundamental and widely studied meshless method in numerical computation. Although it achieves high computational accuracy, the shape functions are more complex than those in the conventional finite element method (FEM), resulting in great computational requirements. Therefore, improving the computational efficiency of the EFG method represents an important research direction. This paper systematically reviews significant contributions from domestic and international scholars in advancing the EFG method. Including the improved element-free Galerkin (IEFG) method, various interpolating EFG methods, four distinct More >

  • Open Access

    ARTICLE

    Numerical Exploration on Load Transfer Characteristics and Optimization of Multi-Layer Composite Pavement Structures Based on Improved Transfer Matrix Method

    Guo-Zhi Li1, Hua-Ping Wang1,2,*, Si-Kai Wang1, Jing-Cheng Zhou1, Ping Xiang3,4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3165-3195, 2025, DOI:10.32604/cmes.2025.072750 - 23 December 2025

    Abstract Transportation structures such as composite pavements and railway foundations typically consist of multi-layered media designed to withstand high bearing capacity. A theoretical understanding of load transfer mechanisms in these multi-layer composites is essential, as it offers intuitive insights into parametric influences and facilitates enhanced structural performance. This paper employs an improved transfer matrix method to address the limitations of existing theoretical approaches for analyzing multi-layer composite structures. By establishing a two-dimensional composite pavement model, it investigates load transfer characteristics and validates the accuracy through finite element simulation. The proposed method offers a straightforward analytical approach… More >

  • Open Access

    ARTICLE

    Novel Quantum-Integrated CNN Model for Improved Human Activity Recognition in Smart Surveillance

    Tanvir Fatima Naik Bukht1,2, Yanfeng Wu1, Nouf Abdullah Almujally3, Shuoa S. AItarbi4, Hameedur Rahman2, Ahmad Jalal2,5,*, Hui Liu1,6,7,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 4013-4036, 2025, DOI:10.32604/cmes.2025.071850 - 23 December 2025

    Abstract Human activity recognition (HAR) is crucial in fields like robotics, surveillance, and healthcare, enabling systems to understand and respond to human actions. Current models often struggle with complex datasets, making accurate recognition challenging. This study proposes a quantum-integrated Convolutional Neural Network (QI-CNN) to enhance HAR performance. The traditional models demonstrate weak performance in transferring learned knowledge between diverse complex data collections, including D3D-HOI and Sysu 3D HOI. HAR requires better extraction models and techniques that must address current challenges to achieve improved accuracy and scalability. The model aims to enhance HAR task performance by combining… More >

  • Open Access

    ARTICLE

    Improved electrochemical performance of nanostructured CO3O4/CO3S4 composite for supercapacitor applications

    J. Ahmada, Naeem-Ur-Rehmana,*, M. Shakila, M. Saleema, K. Mahmoodb, A. Alib, M. Imranc, S. Sharifd, Hosam O. Elansarye, S. Mumtazf, A. D. Khalidg

    Chalcogenide Letters, Vol.22, No.4, pp. 277-292, 2025, DOI:10.15251/CL.2025.224.277

    Abstract This study highlights the superior electrochemical performance of Co3O4/Co3S4 composite nanoparticles for supercapacitors, compared to individual Co3O4 and Co3S4, synthesized using sol-gel, co-precipitation, and mechanical alloying methods. The composite combines pseudocapacitance and electric double-layer capacitance, as evidenced by cyclic voltammetry. It exhibits a specific capacitance of 722.9 F/g at 0.5 A/g and an energy density of 73.8 Wh/kg at 405 W/kg. Electrochemical impedance spectroscopy reveals low charge transfer resistance and excellent cycling stability is achieved, with 98.5% capacitance retention after 1500 cycles. These results confirm the composite's potential for high-performance energy storage applications. More >

  • Open Access

    ARTICLE

    Structural, optical and electrical properties of NiO thin films for hole transport layer in chalcogenide and perovskite materials based solar cells

    M. Abbasa, M. Haseeb-u-Rehmana, M. Sohailb, G. H. Tariqa,*

    Chalcogenide Letters, Vol.22, No.7, pp. 561-577, 2025, DOI:10.15251/CL.2025.227.561

    Abstract This work presents the fabrication of NiO thin films via versatile sol-gel spin coating method and investigation of annealing effects on their physical properties. After the deposition process, the NiO thin films underwent annealing process at different values of temperatures ranging from 200°C to 350°C for one hour duration. XRD patterns confirmed the polycrystalline nature, along the preferred orientations (110) and (101) planes. Nanoparticles in NiO thin films demonstrated an increase in crystallite size with rising annealing temperatures, reaching a maximum size of 49 nm at annealing temperature 300°C. FTIR patterns revealed Ni-O bands at… More >

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