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  • Open Access

    ARTICLE

    Tissue-Specific Transcriptomic Responses and Viral Accumulation in Lily Cultivars Infected with Cucumber Mosaic Virus

    Yun-Im Kang1, Youn Jung Choi1, Su Young Lee1, Young-Ran Lee1, Ki-Byung Lim2,3, Yun-Jae Ahn2,3,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.073138 - 30 January 2026

    Abstract Cucumber mosaic virus (CMV) threatens lily production by reducing floral quality and enabling carry-over via infected planting stock. To explore tissue-specific host responses, we analyzed a legacy, single-replicate RNA-seq dataset from two cultivars, ‘Cancun’ and ‘Connecticut King’ (CK), profiling leaf (source) and bulb (sink) tissues at 0 and 28 days post-inoculation (dpi), alongside leaf DAS-ELISA. Principal component analysis indicated that tissue identity dominated the transcriptome (PC1 = 47.7%), with CMV treatment driving within-tissue shifts over time. Exploratory Gene Ontology/KEGG summaries and a focused marker panel revealed a consistent split: in leaves, genes linked to jasmonate/WRKY-associated… More >

  • Open Access

    ARTICLE

    Machine Learning Models for Predicting Smoking-Related Health Decline and Disease Risk

    Vaskar Chakma1,*, Md Jaheid Hasan Nerab1, Abdur Rouf1, Abu Sayed2, Hossem Md Saim3, Md. Nournabi Khan3

    Journal of Intelligent Medicine and Healthcare, Vol.4, pp. 1-35, 2026, DOI:10.32604/jimh.2026.074347 - 23 January 2026

    Abstract Smoking continues to be a major preventable cause of death worldwide, affecting millions through damage to the heart, metabolism, liver, and kidneys. However, current medical screening methods often miss the early warning signs of smoking-related health problems, leading to late-stage diagnoses when treatment options become limited. This study presents a systematic comparative evaluation of machine learning approaches for smoking-related health risk assessment, emphasizing clinical interpretability and practical deployment over algorithmic innovation. We analyzed health screening data from 55,691 individuals, examining various health indicators including body measurements, blood tests, and demographic information. We tested three advanced… More >

  • Open Access

    ARTICLE

    LP-YOLO: Enhanced Smoke and Fire Detection via Self-Attention and Feature Pyramid Integration

    Qing Long1, Bing Yi2, Haiqiao Liu3,*, Zhiling Peng1, Xiang Liu1

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072058 - 12 January 2026

    Abstract Accurate detection of smoke and fire sources is critical for early fire warning and environmental monitoring. However, conventional detection approaches are highly susceptible to noise, illumination variations, and complex environmental conditions, which often reduce detection accuracy and real-time performance. To address these limitations, we propose Lightweight and Precise YOLO (LP-YOLO), a high-precision detection framework that integrates a self-attention mechanism with a feature pyramid, built upon YOLOv8. First, to overcome the restricted receptive field and parameter redundancy of conventional Convolutional Neural Networks (CNNs), we design an enhanced backbone based on Wavelet Convolutions (WTConv), which expands the… More >

  • Open Access

    ARTICLE

    Spatio-Temporal Earthquake Analysis via Data Warehousing for Big Data-Driven Decision Systems

    Georgia Garani1,*, George Pramantiotis2, Francisco Javier Moreno Arboleda3

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.071509 - 12 January 2026

    Abstract Earthquakes are highly destructive spatio-temporal phenomena whose analysis is essential for disaster preparedness and risk mitigation. Modern seismological research produces vast volumes of heterogeneous data from seismic networks, satellite observations, and geospatial repositories, creating the need for scalable infrastructures capable of integrating and analyzing such data to support intelligent decision-making. Data warehousing technologies provide a robust foundation for this purpose; however, existing earthquake-oriented data warehouses remain limited, often relying on simplified schemas, domain-specific analytics, or cataloguing efforts. This paper presents the design and implementation of a spatio-temporal data warehouse for seismic activity. The framework integrates… More >

  • Open Access

    ARTICLE

    HE4 Might Participate in Extracellular Matrix Remodeling in Ovarian Cancer via Activation of Fibroblasts

    Yimin Liu1,#, Bin Liu2,3,4,#, Huabin Gao1, Jinlong Wang5, Jingya Duan1, Xiaolan Huang1, Yuexi Liu1, Ying Huang1, Wenjing Liao1, Ruonan Li1,*, Hua Linghu1,*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069007 - 30 December 2025

    Abstract Objectives: High-grade serous ovarian cancer (HGSOC), the most common subtype of epithelial ovarian cancer (EOC), exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis. Human epididymis protein 4 (HE4), a key diagnostic biomarker for ovarian cancer, is involved in fibrotic processes in several non-malignant diseases. Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis, this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC. Methods: A total of 126 patients with gynecological conditions were included and divided into… More > Graphic Abstract

    HE4 Might Participate in Extracellular Matrix Remodeling in Ovarian Cancer via Activation of Fibroblasts

  • Open Access

    ARTICLE

    A Transformer-Based Deep Learning Framework with Semantic Encoding and Syntax-Aware LSTM for Fake Electronic News Detection

    Hamza Murad Khan1, Shakila Basheer2, Mohammad Tabrez Quasim3, Raja`a Al-Naimi4, Vijaykumar Varadarajan5, Anwar Khan1,*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-25, 2026, DOI:10.32604/cmc.2025.069327 - 10 November 2025

    Abstract With the increasing growth of online news, fake electronic news detection has become one of the most important paradigms of modern research. Traditional electronic news detection techniques are generally based on contextual understanding, sequential dependencies, and/or data imbalance. This makes distinction between genuine and fabricated news a challenging task. To address this problem, we propose a novel hybrid architecture, T5-SA-LSTM, which synergistically integrates the T5 Transformer for semantically rich contextual embedding with the Self-Attention-enhanced (SA) Long Short-Term Memory (LSTM). The LSTM is trained using the Adam optimizer, which provides faster and more stable convergence compared… More >

  • Open Access

    PROCEEDINGS

    Mechanical Characterisation and Material Modelling of Human Aortas with Vascular Smooth Muscle Activation

    Ivan Breslavsky1,*, Giulio Franchini2, Francesco Giovanniello3, Ali Kassab3,4, Gerhard A. Holzapfel5,6, Marco Amabili1,3

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.34, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.012190

    Abstract Despite the critical role of vascular smooth muscle (VSM) activation in the biomechanics of human aortas, comprehensive experimental data and corresponding active material models remain limited. This study addresses this gap by presenting a detailed mechanical characterisation of human descending thoracic aortas under both passive and VSM-activated conditions.
    Specimens were obtained from thirteen heart-beating donors. Mechanical testing was conducted within hours of explantation. VSM activation was induced using potassium chloride and noradrenaline, and both isometric and quasistatic stress–strain responses were measured in circumferential and longitudinal tissue strips.
    Dynamic mechanical testing under physiologically relevant cyclic loading and More >

  • Open Access

    ARTICLE

    Synergistic Effects of Melatonin and Methyl Jasmonate in Mitigating Drought-Induced Oxidative Stress in Common Bean (Phaseolus vulgaris)

    Totan Kumar Ghosh1, Md. Roushonuzzaman Rakib1, Munna1, S. M. Zubair AL-Meraj1, Md. Moshiul Islam2, Anika Nazran1, Mohammad Golam Mostofa3,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3925-3943, 2025, DOI:10.32604/phyton.2025.073382 - 29 December 2025

    Abstract The productivity of common bean (Phaseolus vulgaris L.), an economically important legume, is severely hindered by drought stress. While melatonin (Mel) and methyl jasmonate (MeJA) are known to alleviate abiotic stresses, their combined effects in mitigating drought-induced oxidative stress are unknown. Here, we examined the synergistic effects of Mel and MeJA in alleviating drought-associated oxidative damage in common bean. Compared with well-watered controls, drought stress caused a significant decline in plant biomass, photosynthetic pigments, and photosystem II efficiency (Fv/Fm). Drought also significantly increased hydrogen peroxide (H2O2) accumulation, which likely contributed to membrane lipid peroxidation, as indicated by… More >

  • Open Access

    ARTICLE

    PPG Based Digital Biomarker for Diabetes Detection with Multiset Spatiotemporal Feature Fusion and XAI

    Mubashir Ali1,2, Jingzhen Li1, Zedong Nie1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 4153-4177, 2025, DOI:10.32604/cmes.2025.073048 - 23 December 2025

    Abstract Diabetes imposes a substantial burden on global healthcare systems. Worldwide, nearly half of individuals with diabetes remain undiagnosed, while conventional diagnostic techniques are often invasive, painful, and expensive. In this study, we propose a noninvasive approach for diabetes detection using photoplethysmography (PPG), which is widely integrated into modern wearable devices. First, we derived velocity plethysmography (VPG) and acceleration plethysmography (APG) signals from PPG to construct multi-channel waveform representations. Second, we introduced a novel multiset spatiotemporal feature fusion framework that integrates hand-crafted temporal, statistical, and nonlinear features with recursive feature elimination and deep feature extraction using… More >

  • Open Access

    ARTICLE

    Double Diffusion Convection in Sisko Nanofluids with Thermal Radiation and Electroosmotic Effects: A Morlet-Wavelet Neural Network Approach

    Arshad Riaz1,*, Misbah Ilyas1, Muhammad Naeem Aslam2, Safia Akram3, Sami Ullah Khan4, Ghaliah Alhamzi5

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3481-3509, 2025, DOI:10.32604/cmes.2025.072513 - 23 December 2025

    Abstract Peristaltic transport of non-Newtonian nanofluids with double diffusion is essential to biological engineering, microfluidics, and manufacturing processes. The authors tackle the key problem of Sisko nanofluids under double diffusion convection with thermal radiations and electroosmotic effects. The study proposes a solution approach by using Morlet-Wavelet Neural Networks that can effectively solve this complex problem by their superior ability in the capture of nonlinear dynamics. These convergence analyses were calculated across fifty independent runs. Theil’s Inequality Coefficient and the Mean Squared Error values range from 10−7 to 10−5 and 10−7 to 10−10, respectively. These values showed the proposed More >

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