CHENYANG CHEN^1,*, JUAN WEN¹, WEI HUANG¹, JIANG LI^2,*

BIOCELL, Vol.47, No.11, pp. 2423-2433, 2023, DOI:10.32604/biocell.2023.044459

Abstract Background: Pulmonary arterial hypertension (PAH) is a chronic and progressive disease that is strongly associated with dysregulation of glucose metabolism. Alterations in nuclear receptor subfamily 4 group A member 1 (NR4A1) activity alter the outcome of PAH. This study aimed to investigate the effects of NR4A1 on glycolysis in PAH and its underlying mechanisms. Methods: This study included twenty healthy volunteers and twenty-three PAH patients, and plasma samples were collected from the participants. To mimic the conditions of PAH in vitro, a hypoxia-induced model of pulmonary artery smooth muscle cell (PASMC) model was established. The proliferation of PASMCs was assessed… More > Graphic Abstract

Dana F. Doghramachi^1,*, Siddeeq Y. Ameen²

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 717-732, 2023, DOI:10.32604/cmc.2023.041186

Abstract The rapid adoption of the Internet of Things (IoT) across industries has revolutionized daily life by providing essential services and leisure activities. However, the inadequate software protection in IoT devices exposes them to cyberattacks with severe consequences. Intrusion Detection Systems (IDS) are vital in mitigating these risks by detecting abnormal network behavior and monitoring safe network traffic. The security research community has shown particular interest in leveraging Machine Learning (ML) approaches to develop practical IDS applications for general cyber networks and IoT environments. However, most available datasets related to Industrial IoT suffer from imbalanced class distributions. This study proposes a… More >

Ali Khan^1,4, Somaiya Khan², Bilal Hassan³, Rizwan Khan^1,4, Zhonglong Zheng^1,4,*

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 403-424, 2023, DOI:10.32604/cmc.2023.040251

Abstract Smoking has an economic and environmental impact on society due to the toxic substances it emits. Convolutional Neural Networks (CNNs) need help describing low-level features and can miss important information. Moreover, accurate smoker detection is vital with minimum false alarms. To answer the issue, the researchers of this paper have turned to a self-attention mechanism inspired by the ViT, which has displayed state-of-the-art performance in the classification task. To effectively enforce the smoking prohibition in non-smoking locations, this work presents a Vision Transformer-inspired model called SmokerViT for detecting smokers. Moreover, this research utilizes a locally curated dataset of 1120 images… More >

Rufus Gikera^1,*, Jonathan Mwaura², Elizaphan Muuro³, Shadrack Mambo³

Journal on Artificial Intelligence, Vol.5, pp. 75-112, 2023, DOI:10.32604/jai.2023.043229

Abstract k-means is a popular clustering algorithm because of its simplicity and scalability to handle large datasets. However, one of its setbacks is the challenge of identifying the correct k-hyperparameter value. Tuning this value correctly is critical for building effective k-means models. The use of the traditional elbow method to help identify this value has a long-standing literature. However, when using this method with certain datasets, smooth curves may appear, making it challenging to identify the k-value due to its unclear nature. On the other hand, various internal validation indexes, which are proposed as a solution to this issue, may be… More >

Qingyun Zeng^1,2, Mingxin Zheng^1,*, Dan Huang²

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.12, pp. 2981-3005, 2023, DOI:10.32604/fdmp.2023.029427

Abstract A complex interface exists between water flow and solid particles during hydraulic soil erosion. In this study, the particle discrete element method (DEM) has been used to simulate the hydraulic erosion of a granular soil under moving bed conditions and surrounding terrain changes. Moreover, the weakly compressible smoothed particle hydrodynamics (WCSPH) approach has been exploited to simulate the instability process of the free surface fluid and its propagation characteristics at the solid–liquid interface. The influence of a suspended medium on the water flow dynamics has been characterized using the mixed viscosity concept accounting for the solid–liquid mixed particle volume ratio.… More > Graphic Abstract

Zhipeng Sheng, Jiasong Meng, Jun Tao^*, Daqiu Zhao^*

Phyton-International Journal of Experimental Botany, Vol.92, No.11, pp. 3133-3147, 2023, DOI:10.32604/phyton.2023.028818

Abstract

Tree peony (Paeonia suffruticosa Andr.) is a traditional Chinese flower, which prefers cool weather. However, high temperature in summer in the middle and lower reaches of the Yangtze River restricts its growth and development. In this study, osmotic regulation, antioxidant enzyme activities, and photosynthetic characteristics of tree peony in response to high-temperature stress were investigated. The results showed that high-temperature stress had destroyed the cell membrane, manifested as the increased relative electrical conductivity and malondialdehyde content. Moreover, high-temperature stress led to excessive accumulation of reactive oxygen species, thereby, activating antioxidant enzyme activities. Also, photosynthetic parameters and chlorophyll fluorescence parameters directly… More >

Océane Phanatzis^1,2,*, Rébecca Ratel^1,2, Isabelle Barcos^1,2, Marie Daspas³, Emmanuelle Clairembault³, François Alla^1,2

Psycho-Oncologie, Vol.17, No.3, pp. 133-145, 2023, DOI:10.32604/po.2023.044916

Abstract Aims: This article aims to explore the interventional and contextual components of smoking cessation support for cancer patients in the context of supportive care in cancer provided by an association, that is viable and effective in the French context, and to describe the partnership research process in which they were developed. Procedure: The intervention was developed from a dataset collected during a viability study for the development of a smoking cessation intervention carried out at the Ligue Contre le Cancer Gironde, a scoping review of evidence-based interventions and two narrative reviews on the determinants and ethical issues of smoking cessation… More >

Dongmei Huang¹, Dang Hong², Wei Li^1,*, Guidong Yang¹, Vesna Rajic³

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.1, pp. 509-524, 2024, DOI:10.32604/cmes.2023.029215

Abstract In this paper, the bifurcation properties of the vibro-impact systems with an uncertain parameter under the impulse and harmonic excitations are investigated. Firstly, by means of the orthogonal polynomial approximation (OPA) method, the nonlinear damping and stiffness are expanded into the linear combination of the state variable. The condition for the appearance of the vibro-impact phenomenon is to be transformed based on the calculation of the mean value. Afterwards, the stochastic vibro-impact system can be turned into an equivalent high-dimensional deterministic non-smooth system. Two different Poincaré sections are chosen to analyze the bifurcation properties and the impact numbers are identified… More >

Asmaa Salah¹, Hoda Sany¹, Abo El-Khair B. El-Sayed², Reham M. El-Bahbohy¹, Heba I. Mohamed^3,*, Ayman Amin^1,*

Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2875-2890, 2023, DOI:10.32604/phyton.2023.031064

Abstract Water is the most essential natural resource for the future development. Agriculture production is extensively water-dependent and a significant polluter of water resources. So, this work investigated the effect of two different preparation media [Bold’s Basal Medium (BBM) and Domiati cheese whey (DCW)] for agricultural drainage water (ADW) remediation. All treatments were incubated for 6 days. According to the results of biomass productivity, specific growth rate, photosynthetic pigments, and biochemical composition, Desmodesmus sp. can grow in drainage water without dilution. The two treatments significantly reduced the concentration of nitrate, phosphate, chemical oxygen demand, and sodium in ADW. Finally, using cheese… More >

Xiang Li¹, Guangyan Huang^1,2,*, Zhiwei Guo^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.4, pp. 1-3, 2023, DOI:10.32604/icces.2023.09269

Abstract SPH method is widely used to study the dynamic response of metal casing under explosive loading because of its superiority in simulating metal fracture phenomenon [1-3]. The distribution of the fragment from uncoupled charge structures with segmental shaped explosive were studied. The X-ray photographic images of fragmentation obtained from explosion experiment were compared with the numerical results based on SPH method and Lagrange method. The fragmentation shows that the numerical results based on the Lagrange method are in good agreement with the experimental results while some errors appear in results based on SPH method. The velocity of the fragments at… More >