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  • Open Access

    ARTICLE

    NAD+ associated genes as potential biomarkers for predicting the prognosis of gastric cancer

    XIANGDONG SUN1,2,#, HUIJUAN WEN1,2,#, FAZHAN LI1,2, IHTISHAM BUKHARI1,2, FEIFEI REN1,2, XIA XUE1,2, PENGYUAN ZHENG1,2,*, YANG MI1,2,*

    Oncology Research, Vol.32, No.2, pp. 283-296, 2024, DOI:10.32604/or.2023.044618

    Abstract Nicotinamide adenine dinucleotide (NAD+) plays an essential role in cellular metabolism, mitochondrial homeostasis, inflammation, and senescence. However, the role of NAD+-regulated genes, including coding and long non-coding genes in cancer development is poorly understood. We constructed a prediction model based on the expression level of NAD+ metabolism-related genes (NMRGs). Furthermore, we validated the expression of NMRGs in gastric cancer (GC) tissues and cell lines; additionally, β-nicotinamide mononucleotide (NMN), a precursor of NAD+, was used to treat the GC cell lines to analyze its effects on the expression level of NMRGs lncRNAs and cellular proliferation, cell cycle, apoptosis, and senescence-associated secretory… More > Graphic Abstract

    NAD+ associated genes as potential biomarkers for predicting the prognosis of gastric cancer

  • Open Access

    ARTICLE

    CRABP2 regulates infiltration of cancer-associated fibroblasts and immune response in melanoma

    SHUANGSHUANG ZENG1,2, XI CHEN1,2, QIAOLI YI1,2, ABHIMANYU THAKUR3, HUI YANG4,*, YUANLIANG YAN1,2, SHAO LIU1,2,*

    Oncology Research, Vol.32, No.2, pp. 261-272, 2024, DOI:10.32604/or.2023.042345

    Abstract Finding biomarkers for immunotherapy is an urgent issue in cancer treatment. Cellular retinoic acid-binding protein 2 (CRABP2) is a controversial factor in the occurrence and development of human tumors. However, there is limited research on the relationship between CRABP2 and immunotherapy response. This study found that negative correlations of CRABP2 and immune checkpoint markers (PD-1, PD-L1, and CTLA-4) were observed in breast invasive carcinoma (BRCA), skin cutaneous melanoma (SKCM), stomach adenocarcinoma (STAD) and testicular germ cell tumors (TGCT). In particular, in SKCM patients who were treated with PD-1 inhibitors, high levels of CRABP2 predicted poor prognosis. Additionally, CRABP2 expression was… More >

  • Open Access

    ARTICLE

    Maximizing Influence in Temporal Social Networks: A Node Feature-Aware Voting Algorithm

    Wenlong Zhu1,2,*, Yu Miao1, Shuangshuang Yang3, Zuozheng Lian1,2, Lianhe Cui1

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3095-3117, 2023, DOI:10.32604/cmc.2023.045646

    Abstract Influence Maximization (IM) aims to select a seed set of size k in a social network so that information can be spread most widely under a specific information propagation model through this set of nodes. However, most existing studies on the IM problem focus on static social network features, while neglecting the features of temporal social networks. To bridge this gap, we focus on node features reflected by their historical interaction behavior in temporal social networks, i.e., interaction attributes and self-similarity, and incorporate them into the influence maximization algorithm and information propagation model. Firstly, we propose a node feature-aware voting… More >

  • Open Access

    ARTICLE

    From Social Media to Ballot Box: Leveraging Location-Aware Sentiment Analysis for Election Predictions

    Asif Khan1, Nada Boudjellal2, Huaping Zhang1,*, Arshad Ahmad3, Maqbool Khan3

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3037-3055, 2023, DOI:10.32604/cmc.2023.044403

    Abstract Predicting election outcomes is a crucial undertaking, and various methods are employed for this purpose, such as traditional opinion polling, and social media analysis. However, traditional polling approaches often struggle to capture the intricate nuances of voter sentiment at local levels, resulting in a limited depth of analysis and understanding. In light of this challenge, this study focuses on predicting elections at the state/regional level along with the country level, intending to offer a comprehensive analysis and deeper insights into the electoral process. To achieve this, the study introduces the Location-Based Election Prediction Model (LEPM), which utilizes social media data,… More >

  • Open Access

    ABSTRACT

    Abstracts from the XLII Annual Meeting of Rosario Society of Biology

    BIOCELL, Vol.47, Suppl.5, pp. 1-23, 2023

    Abstract This article has no abstract. More >

  • Open Access

    ABSTRACT

    Abstracts from the XL Annual Meeting of Sociedad de Biología de Cuyo

    BIOCELL, Vol.47, Suppl.4, pp. 1-83, 2023

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Genetic Diversity, Population Structure, and Genome-Wide Association Study of Seven Agronomic Traits in 273 Diverse Upload Cotton Accessions

    Yajun Liang1,2,#, Juyun Zheng1,#, Junduo Wang1,#, Zhaolong Gong1, Zhiqiang Li3, Ling Min4, Zeliang Zhang2, Zhiwei Sang2, Yanying Qu2, Xueyuan Li1,*, Quanjia Chen2,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.12, pp. 3345-3357, 2023, DOI:10.32604/phyton.2023.028755

    Abstract Upland cotton (Gossypium hirsutum) is the most important plant producing natural fibers for the textile industry. In this study, we first investigated the phenotypic variation of seven agronomic traits of 273 diverse cotton accessions in the years 2017 and 2018, which were from 18 geographical regions. We found large variations among the traits in different geographical regions and only half of the traits in either years 2017 or 2018 followed a normal distribution. We then genotyped the collection with 81,612 high quality SNPs. Phylogenetic tree and population structure revealed a diverse genetic structure of the core collection, and geographical diversification… More >

  • Open Access

    ARTICLE

    A Model for Predicting the Psychological Well-Being of Older Adults in South Korea

    Hyangjin Park1, Haeryun Cho2, So Yeon Yoo3,*

    International Journal of Mental Health Promotion, Vol.25, No.11, pp. 1219-1228, 2023, DOI:10.32604/ijmhp.2023.041490

    Abstract This study examined factors related to the psychological well-being of older adults and built and verified a model for predicting psychological well-being. The participants were 350 older adults aged over 60 years who lived in South Korea and were active in the local community. The model proposed in this study was found to be suitable. Depression, self-efficacy, and social support had a direct effect on the psychological well-being of older adults, while depression, activities of daily living (ADLs), and self-efficacy had an indirect effect. Self-efficacy and social support mediated the relationship between depression and psychological well-being, and self-efficacy mediated the… More >

  • Open Access

    ARTICLE

    On Factorization of N-Qubit Pure States and Complete Entanglement Analysis of 3-Qubit Pure States Containing Exactly Two Terms and Three Terms

    Dhananjay P. Mehendale1,*, Madhav R. Modak2

    Journal of Quantum Computing, Vol.5, pp. 15-24, 2023, DOI:10.32604/jqc.2023.043370

    Abstract A multi-qubit pure quantum state is called separable when it can be factored as the tensor product of 1-qubit pure quantum states. Factorizing a general multi-qubit pure quantum state into the tensor product of its factors (pure states containing a smaller number of qubits) can be a challenging task, especially for highly entangled states. A new criterion based on the proportionality of the rows of certain associated matrices for the existence of certain factorization and a factorization algorithm that follows from this criterion for systematically extracting all the factors is developed in this paper. 3-qubit pure states play a crucial… More >

  • Open Access

    ARTICLE

    Convolutional Neural Network Model for Fire Detection in Real-Time Environment

    Abdul Rehman, Dongsun Kim*, Anand Paul

    CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 2289-2307, 2023, DOI:10.32604/cmc.2023.036435

    Abstract Disasters such as conflagration, toxic smoke, harmful gas or chemical leakage, and many other catastrophes in the industrial environment caused by hazardous distance from the peril are frequent. The calamities are causing massive fiscal and human life casualties. However, Wireless Sensors Network-based adroit monitoring and early warning of these dangerous incidents will hamper fiscal and social fiasco. The authors have proposed an early fire detection system uses machine and/or deep learning algorithms. The article presents an Intelligent Industrial Monitoring System (IIMS) and introduces an Industrial Smart Social Agent (ISSA) in the Industrial SIoT (ISIoT) paradigm. The proffered ISSA empowers smart… More >

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