Zheng Yao^*, Puqing Chang

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-18, 2026, DOI:10.32604/cmc.2025.068248 - 10 November 2025

Abstract As Internet of Things (IoT) applications expand, Mobile Edge Computing (MEC) has emerged as a promising architecture to overcome the real-time processing limitations of mobile devices. Edge-side computation offloading plays a pivotal role in MEC performance but remains challenging due to complex task topologies, conflicting objectives, and limited resources. This paper addresses high-dimensional multi-objective offloading for serial heterogeneous tasks in MEC. We jointly consider task heterogeneity, high-dimensional objectives, and flexible resource scheduling, modeling the problem as a Many-objective optimization. To solve it, we propose a flexible framework integrating an improved cooperative co-evolutionary algorithm based on More >

Yan Gui^1,#, Wen Pan^1,#, Ziyi Dong^1,#, Dongzhi Hu^1,#, Yaoyang Guo¹, Xinyi Wen¹, Haiyang Zhang², Zhansheng Jiang^1,*, Xiangqian Zheng^1,*, Ming Gao^2,*, Junyi Wang^1,*

Oncology Research, Vol.33, No.12, pp. 3991-4011, 2025, DOI:10.32604/or.2025.067182 - 27 November 2025

Abstract Objectives: Metastatic spread to the lung is one of the leading causes of fatal outcomes in thyroid cancer, but the underlying molecular mechanisms remain unclear. To investigate how exosomal microRNA-17-5p (miR-17-5p) promotes lung metastasis in thyroid cancer within the framework of the “seed and soil” hypothesis. Methods: Serum exosomes from thyroid cancer lung metastasis patients and controls were analyzed for miR-17, which was elevated in metastatic cases. miR-17 was transfected into embryonic lung fibroblasts (MRC-5), and their supernatants were co-cultured with thyroid cancer cells (Cal62). Cell proliferation and migration were evaluated using colony formation, Ki67… More >

Miljenko Lapaine^*

Revue Internationale de Géomatique, Vol.34, pp. 793-808, 2025, DOI:10.32604/rig.2025.066916 - 06 November 2025

Abstract The paper investigates the properties of the Lambert equivalent azimuthal projection, which is often used in normal aspect in atlases for maps of the northern and southern hemispheres. The field of research is theoretical in nature and assumes a mastery of mathematics because it deals with map projections. The transverse aspect is commonly used for eastern and western hemisphere atlas maps. In addition, the Hammer projection was created from the transverse aspect of that projection. Therefore, if we want to get to know the Hammer projection better, we must first investigate the Lambert equivalent azimuthal… More >

Sy-Yu Shiau^*, Shuting Ni, Yanli Yu, Songling Cai, Wenbo Huang

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3047-3060, 2025, DOI:10.32604/phyton.2025.070289 - 29 October 2025

Abstract Consumers are increasingly demanding natural colorants that are safe and offer health benefits. In addition to their ornamental characteristics, Kanzan cherry (KC) blossoms present a promising source of red-hued natural colorants and functional bioactive substances. This research utilized distilled water to extract KC petals (KCP) and their ground powders (KCPP) under varying temperatures (30°C–90°C) and times (30–180 min). The total monomeric anthocyanins (TMAC) and total phenolics (TPC) in the extracts were evaluated via the pH differential and Folin–Ciocalteu methods. Antioxidant capacities were assessed by DPPH free radical scavenging ability and reducing power. Results indicated that… More >

Hari Mohan Rai^1,#, Chandra Mukherjee^2,#, Joon Yoo¹, Hanaa A. Abdallah³, Saurabh Agarwal^4,*, Wooguil Pak^4,*

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5723-5745, 2025, DOI:10.32604/cmc.2025.070391 - 23 October 2025

Abstract A hybrid Compressed Sensing and Primal-Dual Wavelet (CSP-PDW) technique is proposed for the compression and reconstruction of ECG signals. The compression and reconstruction algorithms are implemented using four key concepts: Sparsifying Basis, Restricted Isometry Principle, Gaussian Random Matrix, and Convex Minimization. In addition to the conventional compression sensing reconstruction approach, wavelet-based processing is employed to enhance reconstruction efficiency. A mathematical model of the proposed algorithm is derived analytically to obtain the essential parameters of compression sensing, including the sparsifying basis, measurement matrix size, and number of iterations required for reconstructing the original signal and determining More >

Chengru Yang^1,#, Zhiyu Wang^1,#, Shaowu Bi¹, Xinmiao Zhang¹, Zhaoqiang Xu¹, Yifei Ge¹, Tianjie Zhang¹, Nan Wang¹, Yi Xu^{1,2,3,4,5,6,7,8,9,*}, Xiangyu Zhong^1,*

Oncology Research, Vol.33, No.11, pp. 3207-3229, 2025, DOI:10.32604/or.2025.066150 - 22 October 2025

Abstract Pancreatic cancer (PC) is an extremely aggressive cancer of the digestive system with insidious onset and the lack of effective biomarkers, resulting in late-stage diagnosis and poor prognosis. Exosomal non-coding RNAs (ncRNAs) are key mediators of intercellular communication that drive PC initiation and advancement. By modulating gene expression, they impact tumor microenvironment (TME) remodeling, proliferation, migration, apoptosis, and immune evasion. Critically, exosomal ncRNAs serve as promising biomarkers for early diagnosis and prognostic assessment. This review summarizes the current research achievements regarding exosomal ncRNAs in PC, systematically elaborating on their roles in tumor occurrence, metastasis, chemoresistance More >

Nuria Malena Tebez¹, María Cecilia Terrile^1,*, María Elisa Picco¹, María José Iglesias^2,*

BIOCELL, Vol.49, No.10, pp. 1913-1928, 2025, DOI:10.32604/biocell.2025.067833 - 22 October 2025

Abstract In plants, the ubiquitin–proteasome system (UPS) plays a central role in hormonal regulation, including the action of the phytohormone auxin, which orchestrates numerous aspects of growth and development. Auxin modulates redox metabolism and promotes the accumulation of nitric oxide (NO) in various tissues and physiological contexts. NO functions as a redox signaling molecule, exerting its effects in part through the reversible oxidation of cysteine residues via a post-translational modification known as S-nitrosylation. Recent findings highlight a dynamic interplay between S-nitrosylation and the ubiquitination machinery, shaping critical aspects of auxin-mediated plant responses. In this review, we More >

CHIOMA C. EZEUKO^#, SANDANI V. T. WIJERATHNE^#, QIANA L. MATTHEWS^*

BIOCELL, Vol.49, No.9, pp. 1605-1629, 2025, DOI:10.32604/biocell.2025.065474 - 25 September 2025

Abstract Extracellular vesicles (EVs) have arisen as potential therapeutic tools in managing infectious diseases because EVs can regulate cell-to-cell signaling, function as drug transport mechanisms, and influence immune reactions. They are obtained from a myriad of sources, such as plants, humans, and animal cells. EVs like exosomes and ectosomes can be utilized in their native form as therapeutics or engineered to encompass antimicrobials, vaccines, and oligonucleotides of interest with a targeted delivery strategy. An in-depth understanding of host-pathogen dynamics provides a solid foundation for exploiting its full potential in therapeutics against infectious diseases. This review mainly More >

Sumeyra Ucar¹, Muhammed Aldaif ², Esra Yaprak¹, Esma Yigider ², Murat Aydin^2,*, Emre Ilhan¹, Abdulkadir Ciltas², Ertan Yildirim³

Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2461-2477, 2025, DOI:10.32604/phyton.2025.068383 - 29 August 2025

Abstract Wheat is a crucial crop for global food security, and effective in vitro plant regeneration techniques are considered a precondition for genetic engineering in wheat breeding programs. A practical approach for in vitro regeneration of the Kırik bread wheat cultivar via somatic embryogenesis was investigated using endosperm-supported mature embryos. Callus cultures were initiated from mature embryos supported by endosperm, cultured on phytagel-based Murashige and Skoog (MS) basal medium containing dicamba (12 mg/L) and indole-3-acetic acid (IAA) (0.5 mg/L) under dark conditions. This research was designed to examine the impact of putrescine (Put) (0.0 and 1.0 mM) on… More >

Nilüfer Kocak Sahin^*

Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2399-2421, 2025, DOI:10.32604/phyton.2025.067880 - 29 August 2025

Abstract Peanut (Arachis hypogaea) is of international importance as a source of oil and protein. Soil salinity is one of the most significant abiotic stress factors affecting the yield and quality of peanuts. This study evaluated the potential of a seaweed-based biostimulant to enhance emergence and seedling growth of four peanut cultivars (‘Ayse Hanım’, ‘Halis Bey’, ‘NC-7’, and ‘Albenek’) under increasing salinity levels. The experiment was conducted under greenhouse conditions using a randomized complete block design with four replicates. Seeds were sown in trays and treated with two doses of seaweed extract (0 and 5 g L⁻¹) applied… More >