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  • Open Access

    ARTICLE

    Some Important Features of the Lambert Equivalent Azimuthal Projection

    Miljenko Lapaine*

    Revue Internationale de Géomatique, Vol.34, pp. 793-808, 2025, DOI:10.32604/rig.2025.066916 - 06 November 2025

    Abstract The paper investigates the properties of the Lambert equivalent azimuthal projection, which is often used in normal aspect in atlases for maps of the northern and southern hemispheres. The field of research is theoretical in nature and assumes a mastery of mathematics because it deals with map projections. The transverse aspect is commonly used for eastern and western hemisphere atlas maps. In addition, the Hammer projection was created from the transverse aspect of that projection. Therefore, if we want to get to know the Hammer projection better, we must first investigate the Lambert equivalent azimuthal… More >

  • Open Access

    ARTICLE

    Phytochemicals, Antioxidation, and Heat Stability of Aqueous Extracts from Cherry (Prunus serrulata) Petals

    Sy-Yu Shiau*, Shuting Ni, Yanli Yu, Songling Cai, Wenbo Huang

    Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3047-3060, 2025, DOI:10.32604/phyton.2025.070289 - 29 October 2025

    Abstract Consumers are increasingly demanding natural colorants that are safe and offer health benefits. In addition to their ornamental characteristics, Kanzan cherry (KC) blossoms present a promising source of red-hued natural colorants and functional bioactive substances. This research utilized distilled water to extract KC petals (KCP) and their ground powders (KCPP) under varying temperatures (30°C–90°C) and times (30–180 min). The total monomeric anthocyanins (TMAC) and total phenolics (TPC) in the extracts were evaluated via the pH differential and Folin–Ciocalteu methods. Antioxidant capacities were assessed by DPPH free radical scavenging ability and reducing power. Results indicated that… More >

  • Open Access

    ARTICLE

    An Efficient CSP-PDW Approach for ECG Signal Compression and Reconstruction for IoT-Based Healthcare

    Hari Mohan Rai1,#, Chandra Mukherjee2,#, Joon Yoo1, Hanaa A. Abdallah3, Saurabh Agarwal4,*, Wooguil Pak4,*

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5723-5745, 2025, DOI:10.32604/cmc.2025.070391 - 23 October 2025

    Abstract A hybrid Compressed Sensing and Primal-Dual Wavelet (CSP-PDW) technique is proposed for the compression and reconstruction of ECG signals. The compression and reconstruction algorithms are implemented using four key concepts: Sparsifying Basis, Restricted Isometry Principle, Gaussian Random Matrix, and Convex Minimization. In addition to the conventional compression sensing reconstruction approach, wavelet-based processing is employed to enhance reconstruction efficiency. A mathematical model of the proposed algorithm is derived analytically to obtain the essential parameters of compression sensing, including the sparsifying basis, measurement matrix size, and number of iterations required for reconstructing the original signal and determining More >

  • Open Access

    REVIEW

    Exosomal Non-Coding RNAs in Pancreatic Cancer: From Mechanisms to Clinical Applications

    Chengru Yang1,#, Zhiyu Wang1,#, Shaowu Bi1, Xinmiao Zhang1, Zhaoqiang Xu1, Yifei Ge1, Tianjie Zhang1, Nan Wang1, Yi Xu1,2,3,4,5,6,7,8,9,*, Xiangyu Zhong1,*

    Oncology Research, Vol.33, No.11, pp. 3207-3229, 2025, DOI:10.32604/or.2025.066150 - 22 October 2025

    Abstract Pancreatic cancer (PC) is an extremely aggressive cancer of the digestive system with insidious onset and the lack of effective biomarkers, resulting in late-stage diagnosis and poor prognosis. Exosomal non-coding RNAs (ncRNAs) are key mediators of intercellular communication that drive PC initiation and advancement. By modulating gene expression, they impact tumor microenvironment (TME) remodeling, proliferation, migration, apoptosis, and immune evasion. Critically, exosomal ncRNAs serve as promising biomarkers for early diagnosis and prognostic assessment. This review summarizes the current research achievements regarding exosomal ncRNAs in PC, systematically elaborating on their roles in tumor occurrence, metastasis, chemoresistance More >

  • Open Access

    REVIEW

    Auxin-Mediated Redox Control of the Ubiquitin-Proteasome System: A Key Mechanism for Plant Growth and Development

    Nuria Malena Tebez1, María Cecilia Terrile1,*, María Elisa Picco1, María José Iglesias2,*

    BIOCELL, Vol.49, No.10, pp. 1913-1928, 2025, DOI:10.32604/biocell.2025.067833 - 22 October 2025

    Abstract In plants, the ubiquitin–proteasome system (UPS) plays a central role in hormonal regulation, including the action of the phytohormone auxin, which orchestrates numerous aspects of growth and development. Auxin modulates redox metabolism and promotes the accumulation of nitric oxide (NO) in various tissues and physiological contexts. NO functions as a redox signaling molecule, exerting its effects in part through the reversible oxidation of cysteine residues via a post-translational modification known as S-nitrosylation. Recent findings highlight a dynamic interplay between S-nitrosylation and the ubiquitination machinery, shaping critical aspects of auxin-mediated plant responses. In this review, we More >

  • Open Access

    REVIEW

    Extracellular Vesicles as Therapeutic Tools against Infectious Diseases

    CHIOMA C. EZEUKO#, SANDANI V. T. WIJERATHNE#, QIANA L. MATTHEWS*

    BIOCELL, Vol.49, No.9, pp. 1605-1629, 2025, DOI:10.32604/biocell.2025.065474 - 25 September 2025

    Abstract Extracellular vesicles (EVs) have arisen as potential therapeutic tools in managing infectious diseases because EVs can regulate cell-to-cell signaling, function as drug transport mechanisms, and influence immune reactions. They are obtained from a myriad of sources, such as plants, humans, and animal cells. EVs like exosomes and ectosomes can be utilized in their native form as therapeutics or engineered to encompass antimicrobials, vaccines, and oligonucleotides of interest with a targeted delivery strategy. An in-depth understanding of host-pathogen dynamics provides a solid foundation for exploiting its full potential in therapeutics against infectious diseases. This review mainly More >

  • Open Access

    ARTICLE

    Optimizing In Vitro Regeneration of Wheat via Somatic Embryogenesis Using Endosperm-Supported Mature Embryos

    Sumeyra Ucar1, Muhammed Aldaif 2, Esra Yaprak1, Esma Yigider 2, Murat Aydin2,*, Emre Ilhan1, Abdulkadir Ciltas2, Ertan Yildirim3

    Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2461-2477, 2025, DOI:10.32604/phyton.2025.068383 - 29 August 2025

    Abstract Wheat is a crucial crop for global food security, and effective in vitro plant regeneration techniques are considered a precondition for genetic engineering in wheat breeding programs. A practical approach for in vitro regeneration of the Kırik bread wheat cultivar via somatic embryogenesis was investigated using endosperm-supported mature embryos. Callus cultures were initiated from mature embryos supported by endosperm, cultured on phytagel-based Murashige and Skoog (MS) basal medium containing dicamba (12 mg/L) and indole-3-acetic acid (IAA) (0.5 mg/L) under dark conditions. This research was designed to examine the impact of putrescine (Put) (0.0 and 1.0 mM) on… More >

  • Open Access

    ARTICLE

    Evaluation of Seaweeds as Stimulators to Alleviate Salinity-Induced Stress on Some Agronomic Traits of Different Peanut (Arachis hypogaea L.) Cultivars

    Nilüfer Kocak Sahin*

    Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2399-2421, 2025, DOI:10.32604/phyton.2025.067880 - 29 August 2025

    Abstract Peanut (Arachis hypogaea) is of international importance as a source of oil and protein. Soil salinity is one of the most significant abiotic stress factors affecting the yield and quality of peanuts. This study evaluated the potential of a seaweed-based biostimulant to enhance emergence and seedling growth of four peanut cultivars (‘Ayse Hanım’, ‘Halis Bey’, ‘NC-7’, and ‘Albenek’) under increasing salinity levels. The experiment was conducted under greenhouse conditions using a randomized complete block design with four replicates. Seeds were sown in trays and treated with two doses of seaweed extract (0 and 5 g L−1) applied… More >

  • Open Access

    ARTICLE

    Inhibition of Proteasome LMP2 Activity Suppresses Chil3 Expression in Mouse Colon Adenocarcinoma Tissue and Restrains Tumor Growth

    Tatiana M. Astakhova, Nikita S. Karpov, Nataliya O. Dashenkova, Elena V. Alpeeva, Mikhail V. Nesterchuk, Sergey B. Akopov, Arsen S. Mikaelyan, Anfisa S. Ryabchenko, Pavel A. Erokhov, Natalia P. Sharova*

    Oncology Research, Vol.33, No.9, pp. 2573-2595, 2025, DOI:10.32604/or.2025.066611 - 28 August 2025

    Abstract Objectives: Proteasomes, multi-subunit proteases, are key actors of cellular protein catabolism and a number of regulatory processes. The detection of subtle proteasome functioning in tumors may contribute to our understanding of the mechanisms of cancer development. The current study aimed to identify the role of low molecular mass protein 2 (LMP2), a proteasome immune subunit, in the development of mouse colon 26 (C26) adenocarcinoma. Methods: The functions of the LMP2 subunit in tumor development in Balb/c mice were studied using its irreversible inhibitor KZR-504. LMP2 activity was detected by the hydrolysis of the fluorogenic substrate… More >

  • Open Access

    ARTICLE

    MRPL18 Promotes Breast Cancer Progression: Connecting Mitochondrial Ribosomal Protein to Immune Response

    Hailong Li1,#, Wen Ouyang2,#, Yiyin Long1, Yun Peng1, Ziyi Liu1, Qi Zhou1, Rong Xu1,*, Wei Du1,*

    Oncology Research, Vol.33, No.9, pp. 2549-2571, 2025, DOI:10.32604/or.2025.065050 - 28 August 2025

    Abstract Background: The study aimed to explore the clinical value of mitochondrial ribosomal protein L18 (MRPL18) in breast cancer. Methods: Multiple databases were used to validate the expression of MRPL18. The prognostic impact and predictive value of MRPL18 were evaluated by using predictive models. Protein-protein interaction (PPI) networks were constructed by using GeneMANIA. Enrichment analysis is used to explore the signaling pathway regulated by MRPL18. Cell counting kit-8 (CCK-8) assays, colony formation, migration assays, flow cytometry, and xenograft models were employed to evaluate the role of MRPL18 in tumor progression. The immune response of MRPL18 was More >

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