Yonghong Liu¹, Muhammad Waheed², Umair Saleem³, Muhammad Kamran Jamil^4,*, Muhammad Naveed⁵, Mohammad Reza Farahani⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.2, pp. 1899-1916, 2023, DOI:10.32604/cmes.2023.025071

Abstract L-valine is a glycogen-type amino acid regarded among the necessary mammalian amino acids. This is an amino acid that is essential for protein synthesis. N-salicylidene-L-valine is gaining a lot of attention because of its unique structure and increased catalytic and cytotoxic activity. We explore the chain of supramolecular dialkyltin N-salicylidene-L-valine complexes 2, 3, and 4 to learn more about this structure and its features regarding topological indices. We computed the first and second Randić index, harmonic index, sum-connectivity index, atom-bond-connectivity index, geometric arithmetic index and reduced reciprocal Randić index of Supramolecular Chain of Different Complexes of N-Salicylidene-L-Valine. Furthermore, we present… More >

Lilia Oreto^1,*, Giuseppe Mandraffino², Paolo Ciliberti³, Teresa P. Santangelo⁴, Placido Romeo⁵, Antonio Celona⁵, Placido Gitto¹, Lorenzo Galletti³, Fiore S. Iorio³, Alfredo Di Pino¹, Aurelio Secinaro⁴, Paolo Guccione³, Robert H. Anderson⁶, Salvatore Agati¹

Congenital Heart Disease, Vol.18, No.1, pp. 97-111, 2023, DOI:10.32604/chd.2022.023619

Abstract Aims: Evidence is emerging that, in the setting of isomerism, the atrial and bronchial arrangement are not always concordant, nor are these patterns always harmonious with the arrangement of the abdominal organs. We aimed to evaluate the concordance between these features in a cohort of patients with cardiac malformations in the setting of known isomerism, seeking to determine whether it was feasible to assess complexity on this basis, in this regard taking note of the potential value of bronchial as opposed to appendage morphology. Methods and Results: We studied 78 patients known to have isomerism of the bronchuses, 43 with… More > Graphic Abstract

Fairouz Tchier¹, Hassan Khan^2,3,*, Shahbaz Khan², Poom Kumam^4,5, Ioannis Dassios⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.3, pp. 2137-2153, 2023, DOI:10.32604/cmes.2023.022855

Abstract The nonlinearity in many problems occurs because of the complexity of the given physical phenomena. The present paper investigates the non-linear fractional partial differential equations’ solutions using the Caputo operator with Laplace residual power series method. It is found that the present technique has a direct and simple implementation to solve the targeted problems. The comparison of the obtained solutions has been done with actual solutions to the problems. The fractional-order solutions are presented and considered to be the focal point of this research article. The results of the proposed technique are highly accurate and provide useful information about the… More >

USAMA SHARIF AHMAD, KARTHIK SARAVANAN, HONG WAN^*

Oncology Research, Vol.29, No.6, pp. 377-391, 2021, DOI:10.32604/or.2022.026085

Abstract The Yes-associated protein (YAP) is a downstream effector of the Hippo pathway and acts as a key transcription co-factor to regulate cell migration, proliferation, and survival. The Hippo pathway is evolutionarily conserved and controls tissue growth and organ size. Dysregulation and heterogeneity of this pathway are found in cancers, including oral squamous cell carcinoma (OSCC), leading to overexpression of YAP and its regulated proliferation machinery. The activity of YAP is associated with its nuclear expression and is negatively regulated by the Hippo kinase-mediated phosphorylation resulting in an induction of its cytoplasmic translocation. This review focuses on the role of YAP… More >

Aravindan Madhavan^1,*, Yamuna Govindarajan¹, Neelakandan Rajamohan²

Computer Systems Science and Engineering, Vol.45, No.2, pp. 2049-2058, 2023, DOI:10.32604/csse.2023.031566

Abstract In an underdetermined system, compressive sensing can be used to recover the support vector. Greedy algorithms will recover the support vector indices in an iterative manner. Generalized Orthogonal Matching Pursuit (GOMP) is the generalized form of the Orthogonal Matching Pursuit (OMP) algorithm where a number of indices selected per iteration will be greater than or equal to 1. To recover the support vector of unknown signal ‘x’ from the compressed measurements, the restricted isometric property should be satisfied as a sufficient condition. Finding the restricted isometric constant is a non-deterministic polynomial-time hardness problem due to that the coherence of the… More >

Memet Şahin¹, Vakkas Uluçay², S. A. Edalatpanah^3,*, Fayza Abdel Aziz Elsebaee⁴, Hamiden Abd El-Wahed Khalifa⁵

CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 3221-3229, 2023, DOI:10.32604/cmc.2023.033006

Abstract Recently, fuzzy multi-sets have come to the forefront of scientists’ interest and have been used in algebraic structures such as multi-groups, multi-rings, anti-fuzzy multigroup and (α, γ)-anti-fuzzy subgroups. In this paper, we first summarize the knowledge about the algebraic structure of fuzzy multi-sets such as (α, γ)-anti-multi-fuzzy subgroups. In a way, the notion of anti-fuzzy multigroup is an application of anti-fuzzy multi sets to the theory of group. The concept of anti-fuzzy multigroup is a complement of an algebraic structure of a fuzzy multi set that generalizes both the theories of classical group and fuzzy group. The aim of this… More >

Wenhu Wang^1,2,3, Hibba Arshad⁴, Asfand Fahad^4,*, Imran Javaid⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.2, pp. 1685-1699, 2023, DOI:10.32604/cmes.2022.023563

Abstract One of the most recent developments in the field of graph theory is the analysis of networks such as Butterfly networks, Benes networks, Interconnection networks, and David-derived networks using graph theoretic parameters. The topological indices (TIs) have been widely used as graph invariants among various graph theoretic tools. Quantitative structure activity relationships (QSAR) and quantitative structure property relationships (QSPR) need the use of TIs. Different structure-based parameters, such as the degree and distance of vertices in graphs, contribute to the determination of the values of TIs. Among other recently introduced novelties, the classes of ev-degree and ve-degree dependent TIs have… More >

Rui Jiang^1,3,*, Kaisheng Lai², Jianping Xu¹, Xiang Feng¹, Shaoye Wang¹, Xiaojian Wang³, Zhe Liu²

Congenital Heart Disease, Vol.17, No.6, pp. 675-686, 2022, DOI:10.32604/chd.2022.021626

Abstract Background: The etiology of pulmonary arterial hypertension associated with congenital heart disease (PAHCHD) is complicated and the phenotype is heterogeneous. Genetic defects of NOTCH3 were associated with cerebral disease and pulmonary hypertension. However, the relationship between NOTCH3 mutations and the clinical phenotype has not been reported in CHD-PAH. Methods: We eventually enrolled 142 PAH-CHD patients from Fuwai Hospital. Whole exome sequencing (WES) was performed to screen the rare deleterious variants of NOTCH3 gene. Results: This PAH-CHD cohort included 43 (30.3%) men and 99 (69.7%) women with the mean age 29.8 ± 10.9 years old. The pathogenic or likely pathogenic mutations… More >

JIAFU FENG^1,2,#,*, BEI XU^1,2,#, CHUNMEI DAI^1,2,#, YAODONG WANG^1,4, GANG XIE^1,5, WENYU YANG^1,2, BIN ZHANG^1,2, XIAOHAN LI⁶, JUN WANG³

Oncology Research, Vol.29, No.5, pp. 331-349, 2021, DOI:10.32604/or.2022.03554

Abstract Due to its difficulty in early diagnosis and lack of sensitivity to chemotherapy and radiotherapy, renal cell carcinoma (RCC) remains to be a frequent cause of cancer-related death. Here, we probed into new targets for its early diagnosis and treatment for RCC. microRNA (miRNA) data of M2-EVs and RCC were searched on the Gene Expression Omnibus database, followed by the prediction of the potential downstream target. Expression of target genes was measured via RT-qPCR and Western blot, respectively. M2 macrophage was obtained via flow cytometry with M2-EVs extracted. The binding ability of miR-342-3p to NEDD4L and to CEP55 ubiquitination was… More >

Kastriot Zoto¹, Ilir Vardhami², Dušan Bajović³, Zoran D. Mitrović^3,*, Stojan Radenović⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.1, pp. 673-686, 2023, DOI:10.32604/cmes.2022.022878

Abstract The focus of our work is on the most recent results in fixed point theory related to contractive mappings. We describe variants of -contractions that expand, supplement and unify an important work widely discussed in the literature, based on existing classes of interpolative and -contractions. In particular, a large class of contractions in terms of and F for both linear and nonlinear contractions are defined in the framework of -metric-like spaces. The main result in our paper is that --weak contractions have a fixed point in -metric-like spaces if function F or the specified contraction is continuous. As an application… More >