Kastriot Zoto¹, Ilir Vardhami², Dušan Bajović³, Zoran D. Mitrović^3,*, Stojan Radenović⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.1, pp. 673-686, 2023, DOI:10.32604/cmes.2022.022878

Abstract The focus of our work is on the most recent results in fixed point theory related to contractive mappings. We describe variants of -contractions that expand, supplement and unify an important work widely discussed in the literature, based on existing classes of interpolative and -contractions. In particular, a large class of contractions in terms of and F for both linear and nonlinear contractions are defined in the framework of -metric-like spaces. The main result in our paper is that --weak contractions have a fixed point in -metric-like spaces if function F or the specified contraction is continuous. As an application… More >

BINFEN HOU¹, LI ZHAO¹, T IANHAO ZHAO¹, MINGMING YANG¹, WANWAN ZHU¹, XIAODONG CHEN², XIQUAN KE¹, ZHENZENG MA¹, LIN GU¹, MENG WANG¹, MIN DENG^1,*

BIOCELL, Vol.47, No.1, pp. 175-186, 2023, DOI:10.32604/biocell.2022.021359

Abstract Aim: Gastric cancer (GC) is one of the most common malignant tumors. Chrysophanol has been reported to possess antitumor effects on a variety of cancers; however, its role in GC remains unclear. This study aimed to investigate the effects of chrysophanol on the proliferation, pyroptosis, migration, and invasion of GC cells. Methods: Human GC cell lines MKN 28 and AGS cells were treated with different concentrations of chrysophanol, then cell proliferation, migration, invasion and pyroptosis were determined by CCK-8, colony-forming assay, wound healing assay, Transwell assay, and flow cytometry. Cell migration and invasion were reassessed in these transfected cells following… More >

Khalid Hamid¹, Muhammad Waseem Iqbal^2,*, Muhammad Usman Ashraf³, Ahmed Mohammed Alghamdi⁴, Adel A. Bahaddad⁵, Khalid Ali Almarhabi⁶

CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 363-378, 2023, DOI:10.32604/cmc.2023.032271

Abstract Due to a tremendous increase in mobile traffic, mobile operators have started to restructure their networks to offload their traffic. New research directions will lead to fundamental changes in the design of future Fifth-generation (5G) cellular networks. For the formal reason, the study solves the physical network of the mobile base station for the prediction of the best characteristics to develop an enhanced network with the help of graph theory. Any number that can be uniquely calculated by a graph is known as a graph invariant. During the last two decades, innumerable numerical graph invariants have been portrayed and used… More >

R. T. Pavendan^1,*, K. Sankar¹, K. A. Varun Kumar²

Intelligent Automation & Soft Computing, Vol.35, No.3, pp. 3331-3348, 2023, DOI:10.32604/iasc.2023.028029

Abstract Attacks on the cyber space is getting exponential in recent times. Illegal penetrations and breaches are real threats to the individuals and organizations. Conventional security systems are good enough to detect the known threats but when it comes to Advanced Persistent Threats (APTs) they fails. These APTs are targeted, more sophisticated and very persistent and incorporates lot of evasive techniques to bypass the existing defenses. Hence, there is a need for an effective defense system that can achieve a complete reliance of security. To address the above-mentioned issues, this paper proposes a novel honeypot system that tracks the anonymous behavior… More >

JÉRÔME LALOZE^1,2, ALEXIS DESMOULIÈRE^1,*

BIOCELL, Vol.46, No.12, pp. 2701-2704, 2022, DOI:10.32604/biocell.2022.022229

Abstract Advances in regenerative medicine correlate strongly with progress in the use of adipose tissue-derived mesenchymal stem/stromal cells. The range of therapeutic indications has also expanded over recent years. Numerous recent studies have highlighted the primary importance of paracrine secretion by these cells. Though it is interesting to compare the different types of such secretions, we believe that exosomes (extra-cellular vesicles possessing the same properties as their source cells) will likely be the main key in tomorrow’s cell therapy. Exosomes also have many advantages compared to the direct use of cells, making these particles a major target in fundamental and translational… More >

Hye Kyung Kim^1,*, Dae Sik Lee²

CMES-Computer Modeling in Engineering & Sciences, Vol.133, No.3, pp. 825-842, 2022, DOI:10.32604/cmes.2022.022103

Abstract The generating functions of special numbers and polynomials have various applications in many fields as well as mathematics and physics. In recent years, some mathematicians have studied degenerate version of them and obtained many interesting results. With this in mind, in this paper, we introduce the degenerate r-Dowling polynomials and numbers associated with the degenerate r-Whitney numbers of the second kind. We derive many interesting properties and identities for them including generating functions, Dobinski-like formula, integral representations, recurrence relations, differential equation and various explicit expressions. In addition, we explore some expressions for them that can be derived from repeated applications… More >

Eman K. Elsayed¹, Asmaa K. Elsayed^2,*, Kamal A. Eldahshan³

CMC-Computers, Materials & Continua, Vol.73, No.3, pp. 5103-5120, 2022, DOI:10.32604/cmc.2022.030803

Abstract Industry 4.0 production environments and smart manufacturing systems integrate both the physical and decision-making aspects of manufacturing operations into autonomous and decentralized systems. One of the key aspects of these systems is a production planning, specifically, Scheduling operations on the machines. To cope with this problem, this paper proposed a Deep Reinforcement Learning with an Actor-Critic algorithm (DRLAC). We model the Job-Shop Scheduling Problem (JSSP) as a Markov Decision Process (MDP), represent the state of a JSSP as simple Graph Isomorphism Networks (GIN) to extract nodes features during scheduling, and derive the policy of optimal scheduling which guides the included… More >

CHANG CHEN^1,#, LIMIN QIAO^2,#, KAIJUN GUO¹, YINGQIU WANG¹, MENGYI YUAN³, BOFAN FU⁴, XIAOBO GAO³, HEMIN NI¹, LONGFEI XIAO^1,*, XIANGGUO WANG^1,*

BIOCELL, Vol.46, No.11, pp. 2415-2423, 2022, DOI:10.32604/biocell.2022.021510

Abstract Endometritis affects the reproductive capacity of dairy cows and leads to serious economic losses in dairy farming. Clarification of the pathogenesis of endometritis is necessary to improve the reproductive efficiency of dairy cows. Exosomes and their miRNAs have been proven to play an important role in inflammatory regulation. Exosomal miR-218 is a differentially expressed miRNA found in endometrial epithelial cells (EECs) under endometrial inflammation. Therefore, we investigated the expression of miR-218 in the uterine tissue of dairy cows, lipopolysaccharide (LPS) treated EECs, exosomal vesicles, and regulation of exosomal miR-218 by targeting TGIF-2 inducible factor homology frame 2 (TGIF2)/transforming growth factor-beta… More >

Haojie Zhang¹, Xiaohong Wang^2,*, Yue Yu², Zhenlin Yang^3,*

Oncologie, Vol.24, No.2, pp. 247-259, 2022, DOI:10.32604/oncologie.2022.020993

Abstract Chemotherapy plays an important role in controlling cancer progression, but the long-term use of chemotherapeutic agents can lead to drug resistance and eventually treatment failure. Therefore, elucidation of the mechanism of drug resistance is the key to solve the problem of chemotherapy resistance. In recent years, exosomes derived from tumor cells have received extensive attention from researchers. In this paper, we reviewed the role and mechanism of exosome-mediated tumor drug resistance in recent years, summarized the related studies of exosome and chemotherapy drug resistance, and focused on several different ways by which exosomes participate in tumor drug resistance. It includes… More >

Ghulam Muhiuddin^1,*, Waseem A. Khan², Deena Al-Kadi³

CMES-Computer Modeling in Engineering & Sciences, Vol.132, No.3, pp. 763-779, 2022, DOI:10.32604/cmes.2022.017272

Abstract In this paper, we introduce modied degenerate polyexponential Cauchy (or poly-Cauchy) polynomials and numbers of the second kind and investigate some identities of these polynomials. We derive recurrence relations and the relationship between special polynomials and numbers. Also, we introduce modied degenerate unipolyCauchy polynomials of the second kind and derive some fruitful properties of these polynomials. In addition, positive associated beautiful zeros and graphical representations are displayed with the help of Mathematica. More >