YANG LI^1,2, JIAN LIU^1,3,*, YUEDI HU^1,2, CHENGZHI CONG^1,2, YIMING CHEN^1,2, QIAO ZHOU^1,2

BIOCELL, Vol.48, No.1, pp. 9-19, 2024, DOI:10.32604/biocell.2023.045862

Abstract Rheumatoid arthritis (RA) is a prevalent autoimmune disease whose main features include chronic synovial inflammation, bone destruction, and joint degeneration. Neutrophils are often considered to be the first responders to inflammation and are a key presence in the inflammatory milieu of RA. Neutrophil extracellular traps (NETs), a meshwork of DNA-histone complexes and proteins released by activated neutrophils, are widely involved in the pathophysiology of autoimmune diseases, especially RA, in addition to playing a key role in the neutrophil innate immune response. NETs have been found to be an important source of citrullinated autoantigen antibodies and inflammatory factor release, which can… More > Graphic Abstract

PING YANG^1,2,3, YUANXIANG LAN^1,2, ZHONG ZENG^1,2, YAN WANG^1,2, HECHUN XIA^1,2,*

BIOCELL, Vol.48, No.1, pp. 149-162, 2024, DOI:10.32604/biocell.2023.042367

Abstract Background: As a form of biological therapy, placenta-derived mesenchymal stem cells (PDMSCs) exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury (TBI) due to their multi-target and multi-pathway mode of action. Material & Methods: This study investigates the protective mechanisms and benefits of PDMSCs in mitigating the effects of controlled cortical impact (CCI) in rats and glutamate-induced oxidative stress injury in HT22 cells in vitro. Our primary objective is to provide evidence supporting the clinical application of PDMSCs. Results: In the in vivo arm of our investigation, we observed a swift elevation of matrix metalloproteinase-9 (MMP-9) in… More > Graphic Abstract

Qi Li, Jinsheng Hu^*, Peng Wan

International Journal of Mental Health Promotion, Vol.25, No.11, pp. 1173-1186, 2023, DOI:10.32604/ijmhp.2023.030343

Abstract

Given the ongoing character of COVID-19, higher-education students encountered multifaceted pressures brought about by the pandemic and had to overcome many difficulties during this period. Accordingly, it is imperative to identify the factors that may have protective effects on the social functioning and mental status of college students in the aftermath of COVID-19. This cross-sectional study sought to ascertain the internal mechanism of positive coping (PC) styles affecting post-traumatic growth (PTG) and considered the mediating roles of cognitive reappraisal (CR), psychological resilience (PR), and deliberate rumination (DR), which are essential for understanding how and to what extent these factors shaped… More >

Cuirong Xu^1,*, Han Yan², Dawei Xu³, Guanjie Chen⁵, Qian Xu², Kunpeng Li⁶, Yehao Rui⁷, Zanmin Song³, Neeraj Gill³, Jing Sun^3,4,*

International Journal of Mental Health Promotion, Vol.25, No.10, pp. 1089-1102, 2023, DOI:10.32604/ijmhp.2023.030526

Abstract Objective: The purpose of this study was to evaluate the effectiveness of post-traumatic growth (PTG) model-based intervention to improve positive psychological traits in Chinese breast cancer patients. Design: A randomized control trial of a psychological group intervention based on PTG model. Methods: The Clinical Trial was registered on 17 August 2019 at Chinese Clinical Trials.gov with Registration number ChiCTR1900025264. A total of 92 patients with breast cancer were recruited. The participants were randomly assigned to the experimental group (n = 46) and the control group (n = 46). A six-session psychological group intervention based on PTG model was implemented in… More >

Jonathan T. Wolkinson, Michael Weinberg^*

International Journal of Mental Health Promotion, Vol.25, No.10, pp. 1137-1145, 2023, DOI:10.32604/ijmhp.2023.029641

Abstract Living under ongoing shelling and missile attacks could cause a widespread of disruption of everyday life and emotional distress. Coping with such distress could be associated with the personal resources of religion and spirituality. The present study aimed to examine the relationships between religiosity and spirituality with Post Traumatic stress Disorder (PTSD) symptoms among a civilian population frequently exposed to missile and rocket threats. One hundred and twenty-four (N = 124) civilian participants living within 10 km from shelling and missile attacks fired towards them, completed demographic, religiosity, spirituality, and PTSD questionnaires. The study findings demonstrate that religiosity is associated… More >

M. Laget, L. Fasse, B. Fresneau, E. Ricadat, S. Rivollet

Psycho-Oncologie, Vol.16, No.2, pp. 267-272, 2022, DOI:10.3166/pson-2022-0190

Abstract Dans le cadre du dispositif de suivi médical destiné aux adultes guéris d’un cancer pédiatrique à l’Institut Gustave-Roussy (Villejuif, France), un entretien psychologique est proposé. Cet article s’appuie sur 198 entretiens auprès de patients ayant entre 18 et 67 ans, diagnostiqués entre 0 et 24 ans. Ces rencontres donnent à entendre la subjectivité du vécu du cancer et de la guérison, révélant les traces de cette expérience dans l’après-coup. Les enjeux de l’activité narrative amorcée dans le cadre de cette consultation, et pouvant se poursuivre au-delà, sont abordés dans une perspective métapsychologique. More >

JIAN LI¹, QINGQING WANG², XIAOYING ZHANG^1,*

BIOCELL, Vol.47, No.6, pp. 1307-1316, 2023, DOI:10.32604/biocell.2023.028714

Abstract Scutellarin (SCU) is a herbal flavonoid glucuronide with multiple pharmacological activities, including anti-oxidant, anti-inflammation, vascular relaxation, anti-platelet, and myocardial protection. However, the effect of SCU on complete Freund’s adjuvant (CFA)-induced rheumatoid arthritis (RA) had not been studied. In this study, we investigated the beneficial effects of SCU in the CFA-induced RA mice model and the anti-arthritic activity was evaluated by paw edema. Enzyme-linked immunosorbent assay (ELISA) was carried out to evaluate the plasma levels of immunoglobulin (Ig)G, IgE, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, receptor activator of nuclear factor-κB ligand (RANKL), and osteoprotegerin (OPG). Histological slides were prepared from… More >

Erhabor S. Idemudia¹, Babatola D. Olawa^1,*, Gail E. Wyatt², Norweeta G. Milburn²

International Journal of Mental Health Promotion, Vol.25, No.5, pp. 699-710, 2023, DOI:10.32604/ijmhp.2023.026852

Abstract It is established in the psychological literature that pre-displacement stressors, PTSD symptoms, and psychological distress are associated among internally displaced persons. However, existing studies have not demonstrated the mechanism underlying these associations. This study compared two explanatory models; one with PTSD symptoms severity explaining the indirect association between pre-displacement stressors and psychological distress, and the other with psychological distress explaining the indirect relationship between pre-displacement stressors and PTSD symptoms severity. In a cross-sectional design, 631 women (Mean age = 31.18 ± 8.59) were conveniently and purposely selected from the displaced women harboured in two camps in Borno State, Nigeria, due… More >

Zhimin Zhao^1,2, Jie Yan³, Shangbin Wang^1,2, Yuanhao Tie⁴, Ning Feng^1,2,5,*

Sound & Vibration, Vol.56, No.4, pp. 307-317, 2022, DOI:10.32604/sv.2022.028797

Abstract This paper theoretically introduced the feasibility of changing the vibration characteristics of flexible plates by using bio-inspired, extremely light, and powerful Pneumatic Artificial Muscle (PAM) actuators. Many structural plates or shells are typically flexible and show high vibration sensitivity. For this reason, this paper provides a way to achieve active vibration control for suppressing the oscillations of these structures to meet strict stability, safety, and comfort requirements. The dynamic behaviors of the designed plates are modeled by using the finite element (FE) method. As is known, the output force vs. contraction curve of PAM is nonlinear generally. In this present… More >

Yunyoung Nam¹, Seong Jun Choi², Jihwan Shin¹, Jinseok Lee^3,*

Computer Systems Science and Engineering, Vol.46, No.2, pp. 1521-1532, 2023, DOI:10.32604/csse.2023.034192

Abstract An otoscope is traditionally used to examine the eardrum and ear canal. A diagnosis of otitis media (OM) relies on the experience of clinicians. If an examiner lacks experience, the examination may be difficult and time-consuming. This paper presents an ear disease classification method using middle ear images based on a convolutional neural network (CNN). Especially the segmentation and classification networks are used to classify an otoscopic image into six classes: normal, acute otitis media (AOM), otitis media with effusion (OME), chronic otitis media (COM), congenital cholesteatoma (CC) and traumatic perforations (TMPs). The Mask R-CNN is utilized for the segmentation… More >