Liping Yang^1,#, Xin Wan^2,3,#, Runyang Zhou¹, Yingdan Yuan^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.1, pp. 81-96, 2024, DOI:10.32604/phyton.2023.045389

Abstract As one of the main active components of Dendrobium catenatum, alkaloids have high medicinal value. The physicochemical properties, conserved domains and motifs, phylogenetic analysis, and cis-acting elements of the gene family members in the alkaloid biosynthesis pathway of D. catenatum were analyzed by bioinformatics, and the expression of the genes in different years and tissues was analyzed by qRT-PCR. There are 16 gene families, including 25 genes, in the D. catenatum alkaloid biosynthesis pathway. The analysis of conserved domains and motifs showed that the types, quantities, and orders of domains and motifs were similar among members of the same family,… More >

Kesheng Lin^1,2, Jiawen Zhou^1,2, Lijuan Han^1,2, Ning Li^1,2,*

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 285-296, 2023, DOI:10.32604/phyton.2022.023219

Abstract As a traditional herbal medicine, the major alkaloids in Uncaria rhynchophylla have been proven to have blood pressure-lowering and sedative effects. It is essential to develop an effective method for the determination of the major alkaloids in U. rhynchophylla. In this research, a rapid quantitative analysis involving multi-components analysis by a single marker strategy coupled with core-shell column HPLC was adopted to analyse four alkaloids (corynoxeine, isocorynoxeine, isorhynchophylline, rhynchophylline) in U. rhynchophylla. Isorhynchophylline was selected as the internal reference substance, the content of which was determined by the traditional external standard method. Relative correction factors (RCF) between isorhynchophylline and the… More >

Lohanathan Bharathi Priya^1,#, Balamuralikrishnan Balasubramanian^2,#, Balamurugan Shanmugaraj³, Shanmugam Subbiah⁴, Rouh-Mei Hu⁵, Chih-Yang Huang^6,7,8,9,*, Rathinasamy Baskaran^5,*

Phyton-International Journal of Experimental Botany, Vol.91, No.6, pp. 1129-1140, 2022, DOI:10.32604/phyton.2022.017707

Abstract For thousands of years, plant based herbal medicines have been utilized by millions of people all over the world. Plant materials or products are used in different folk/traditional medical systems, such as the Chinese, African and Indian medical systems, like Siddha, Ayurveda, Unani, and Homeopathy. Tinospora cordifolia (TC) is a medicinal plant belonging to the family Menispermaceae. It is a big deciduous, climbing shrub growing prevalently in the tropical part of Indian subcontinent regions such as India, Pakistan, Nepal, Bhutan, Bangladesh and Srilanka, and in Myanmar, and China. Guduchi, Giloy, Shindilkodi, and Amritha are all the common names for this… More >

JIANFEI GAO¹, KANGNING XIONG^2,*, WEIJIE LI¹, WEI ZHOU³

BIOCELL, Vol.46, No.1, pp. 285-296, 2022, DOI:10.32604/biocell.2021.016253

Abstract Kadsura coccinea (Lem.) is a woody wine plant with a peculiar fruit enriched in important health-promoting compounds. The non-editable part of the fruit, i.e., the seed and peel, represents more than 60% of the fruit and is considered a biowaste. This significantly restricts the development of the K. coccinea fruit industry. Clarifying the metabolic components of the different fruit parts can help to improve the utilization rate and valorization of K. coccinea. Herein, we evaluated K. coccinea fruit peel, pulp, and seed using widely-targeted metabolomics and quantified a set of 736 bioactive compounds from 11 major metabolite classes. The most… More >

Imad Ahmad^1,2, Haroon Khan^2,*, Muhammad Usman Amin¹, Shah Khalid³, Tapan Behl⁴, Najeeb Ur Rahman¹

Oncologie, Vol.23, No.3, pp. 321-333, 2021, DOI:10.32604/Oncologie.2021.018296

Abstract Punarnavine (PN) has been isolated from the roots of Boerhaavia diffusa L. (Nyctaginaceae). It is an important medicinal plant with a vast historical ethnopharmacological background. Its identification resulted from the interrogation of ‘Punarnava’, a tribal medicinal product. The molecule exhibited its position as incipient anticancer therapeutic agent. The inhibition of NFκB, ATF-2, c-Fos, and CREB-1 are one of the underlying mechanisms of anticancer action along with modification of the immune system. These signalling molecules are upregulated in the cancer microenvironment. Punarnavine also modified the release of interleukins, i.e., upregulated IL-2, IL-7, IL-10, IL-12, IFN-γ, while downregulated IL-1β, IL-6, TNF-α, VEGF,… More >

Mohammed Ali Ashehri^*

Phyton-International Journal of Experimental Botany, Vol.90, No.6, pp. 1749-1762, 2021, DOI:10.32604/phyton.2021.016290

Abstract In most of Arabian courtiers Rhazya stricta is extensively utilized in public medicine for several diseases treatment. In this study, crude alkaloid extract of R. stricta (CAERS) coated with silver nanoparticles (CAERS-AgNPs) as potential treatment against diabetes in DM animal model was evaluated. Swiss albino male rats (n = 80) were injected with STZ to induce Diabetes Mellitus type-2 (DM). DM-rats were injected different doses of CAERS or CAERS-nanoparticles (CAERS-NPs) for 2 months. The results exhibited that mRNA expression of insulin and insulin receptor was down-regulated, activity levels of antioxidant enzymes were decreased, generation of ROS mediated DNA adducts and apoptosis in… More >

Guiming Deng^1,2,3, Ou Sheng^1,2,3, Fangcheng Bi^1,2,3, Chunyu Li^1,2,3, Tongxin Dou^1,2,3, Tao Dong^1,2,3, Qiaosong Yang^1,2,3, Huijun Gao^1,2,3, Jing Liu⁴, Xiaohong Zhong⁴, Miao Peng⁴, Ganjun Yi^1,2,3, Weidi He^1,2,3, Chunhua Hu^1,2,3,*

Phyton-International Journal of Experimental Botany, Vol.89, No.4, pp. 1101-1130, 2020, DOI:10.32604/phyton.2020.010970

Abstract Banana (Musa spp.) is an ancient and popular fruit plant with highly nutritious fruit. The pseudo-stem of banana represents on average 75% of the total dry mass but its valorization as a nutritional and industrial by-product is limited. Recent advances in metabolomics have paved the way to understand and evaluate the presence of diverse sets of metabolites in different plant parts. This study aimed at exploring the diversity of primary and secondary metabolites in the banana pseudo-stem. Hereby, we identified and quantified 373 metabolites from a diverse range of classes including, alkaloids, flavonoids, lipids, phenolic acids, amino acids and its… More >

Pérez-Amador¹ MC, V Muñoz Ocotero¹, JM García Castañeda¹, AR González Esquinca²

Phyton-International Journal of Experimental Botany, Vol.76, pp. 39-45, 2007, DOI:10.32604/phyton.2007.76.039

Abstract A comparison was made between plants of Solanum torvum Sw that grow in Chiapas, Mexico, and plants of the same species originating from India. This was effected to establish either similarities or differences between these plants in total alkaloid contents and presence of solasodine, an important alkaloid for the partial synthesis of steroids. The total alkaloid content (0.12%) of the plants coming from Chiapas and India was the same. However, solasodine was found only in the plants of Chiapas. In addition, the total amount of glycoalkaloids (0.038%) and two glycosilated compounds derived from solasodine, solasonine (0.0043%) and solamargine (0.0028%), were… More >