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  • Open Access

    ARTICLE

    A Multi-Block Material Balance Framework for Connectivity Evaluation and Optimization of Water-Drive Gas Reservoirs

    Fankun Meng1,2,3, Yuyang Liu1,2,*, Xiaohua Liu4, Chenlong Duan1,2, Yuhui Zhou1,2,3

    FDMP-Fluid Dynamics & Materials Processing, Vol.22, No.1, 2026, DOI:10.32604/fdmp.2026.075865 - 06 February 2026

    Abstract Carbonate gas reservoirs are often characterized by strong heterogeneity, complex inter-well connectivity, extensive edge or bottom water, and unbalanced production, challenges that are also common in many heterogeneous gas reservoirs with intricate storage and flow behavior. To address these issues within a unified, data-driven framework, this study develops a multi-block material balance model that accounts for inter-block flow and aquifer influx, and is applicable to a wide range of reservoir types. The model incorporates inter-well and well-group conductive connectivity together with pseudo–steady-state aquifer support. The governing equations are solved using a Newton–Raphson scheme, while particle More > Graphic Abstract

    A Multi-Block Material Balance Framework for Connectivity Evaluation and Optimization of Water-Drive Gas Reservoirs

  • Open Access

    ARTICLE

    Flowback Behavior of Deep Coalbed Methane Horizontal Wells

    Wei Sun1,2, Yanqing Feng1,2,*, Yuan Wang1,2, Zengping Zhao1,2, Qian Wang2, Xiangyun Li3, Dong Feng4

    FDMP-Fluid Dynamics & Materials Processing, Vol.22, No.1, 2026, DOI:10.32604/fdmp.2026.075630 - 06 February 2026

    Abstract Significant differences exist between deep and medium-shallow coalbed methane (CBM) reservoirs. The unclear understanding of flowback and production behavior severely constrains the development of deep CBM resources. To address this challenge, guided by the gas-liquid two-phase flow theory in ultra-low permeability reservoirs, and integrating theoretical analysis, numerical simulation, and insights from production practices, this study classifies the flowback and production stages of deep CBM well considering the Daning-Jixian Block, Eastern Ordos Basin as a representative case. We summarize the flowback characteristics for each stage and establish a standard flowback production type curve, aiming to guide… More > Graphic Abstract

    Flowback Behavior of Deep Coalbed Methane Horizontal Wells

  • Open Access

    REVIEW

    A Systematic Review of Frameworks for the Detection and Prevention of Card-Not-Present (CNP) Fraud

    Kwabena Owusu-Mensah*, Edward Danso Ansong , Kofi Sarpong Adu-Manu, Winfred Yaokumah

    Journal of Cyber Security, Vol.8, pp. 33-92, 2026, DOI:10.32604/jcs.2026.074265 - 20 January 2026

    Abstract The rapid growth of digital payment systems and remote financial services has led to a significant increase in Card-Not-Present (CNP) fraud, which is now the primary source of card-related losses worldwide. Traditional rule-based fraud detection methods are becoming insufficient due to several challenges, including data imbalance, concept drift, privacy concerns, and limited interpretability. In response to these issues, a systematic review of twenty-four CNP fraud detection frameworks developed between 2014 and 2025 was conducted. This review aimed to identify the technologies, strategies, and design considerations necessary for adaptive solutions that align with evolving regulatory standards.… More >

  • Open Access

    ARTICLE

    Gut Associated Metabolites Enhance PD-L1 Blockade Efficacy in Prostate Cancer

    Ke Liu1,2,3,#, Xia Xue1,2,3,#, Haiming Qin4,5,#, Jiaying Zhu6,#, Meng Jin1,6, Die Dai6, Youcai Tang1, Ihtisham Bukhari1, Hangfan Liu1, Chunjing Qiu1, Feifei Ren1, Pengyuan Zheng1,2,3, Yang Mi1,2,3,*, Weihua Chen6,7,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.072661 - 19 January 2026

    Abstract Background: The gut microbiome has emerged as a critical modulator of cancer immunotherapy response. However, the mechanisms by which gut-associated metabolites influence checkpoint blockade efficacy in prostate cancer (PC) remain not fully explored. The study aimed to explore how gut metabolites regulate death-ligand 1 (PD-L1) blockade via exosomes and boost immune checkpoint inhibitors (ICIs) in PC. Methods: We recruited 70 PC patients to set up into five subgroups. The integrated multi-omics analysis was performed. In parallel, we validated the function of gut microbiome-associated metabolites on PD-L1 production and immunotherapy treatment efficacy in PC cell lines… More >

  • Open Access

    REVIEW

    The Frontier of Melanoma Treatment: Defeating Immunotherapy Resistance—A Systematic Review

    Kamila Mozga1, Olga Synowiecka1, Igor Rydzyk1, Anna Marek1, Ewelina Wieczorek1, Alicja Petniak2,*, Paulina Gil-Kulik2

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.070505 - 19 January 2026

    Abstract Objectives: Immunotherapy based on immune checkpoint blockade (ICB) has become a key treatment for melanoma. However, the increasing number of cases of melanoma resistant to immunotherapy highlights the need to develop methods to overcome this resistance. This study aims to collect the most recent information on melanoma immunotherapy, discuss potential strategies to overcome resistance to immunotherapy, and identify areas that require further analysis. Methods: To achieve this goal, scientific publications from 2021–2024 available in PubMed and Google Scholar databases were analyzed. The databases were searched using the following terms: “melanoma”, “immunotherapy”, “Immune Checkpoint Blockade”, and More >

  • Open Access

    ARTICLE

    HATLedger: An Approach to Hybrid Account and Transaction Partitioning for Sharded Permissioned Blockchains

    Shuai Zhao, Zhiwei Zhang*, Junkai Wang, Ye Yuan, Guoren Wang

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.073315 - 12 January 2026

    Abstract With the development of sharded blockchains, high cross-shard rates and load imbalance have emerged as major challenges. Account partitioning based on hashing and real-time load faces the issue of high cross-shard rates. Account partitioning based on historical transaction graphs is effective in reducing cross-shard rates but suffers from load imbalance and limited adaptability to dynamic workloads. Meanwhile, because of the coupling between consensus and execution, a target shard must receive both the partitioned transactions and the partitioned accounts before initiating consensus and execution. However, we observe that transaction partitioning and subsequent consensus do not require… More >

  • Open Access

    ARTICLE

    Secured-FL: Blockchain-Based Defense against Adversarial Attacks on Federated Learning Models

    Bello Musa Yakubu1,*, Nor Shahida Mohd Jamail 2, Rabia Latif 2, Seemab Latif 3

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072426 - 12 January 2026

    Abstract Federated Learning (FL) enables joint training over distributed devices without data exchange but is highly vulnerable to attacks by adversaries in the form of model poisoning and malicious update injection. This work proposes Secured-FL, a blockchain-based defensive framework that combines smart contract–based authentication, clustering-driven outlier elimination, and dynamic threshold adjustment to defend against adversarial attacks. The framework was implemented on a private Ethereum network with a Proof-of-Authority consensus algorithm to ensure tamper-resistant and auditable model updates. Large-scale simulation on the Cyber Data dataset, under up to 50% malicious client settings, demonstrates Secured-FL achieves 6%–12% higher accuracy, More >

  • Open Access

    ARTICLE

    A Novel Signature-Based Secure Intrusion Detection for Smart Transportation Systems

    Hanaa Nafea1, Awais Qasim2, Sana Abdul Sattar2, Adeel Munawar3, Muhammad Nadeem Ali4, Byung-Seo Kim4,*

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072281 - 12 January 2026

    Abstract The increased connectivity and reliance on digital technologies have exposed smart transportation systems to various cyber threats, making intrusion detection a critical aspect of ensuring their secure operation. Traditional intrusion detection systems have limitations in terms of centralized architecture, lack of transparency, and vulnerability to single points of failure. This is where the integration of blockchain technology with signature-based intrusion detection can provide a robust and decentralized solution for securing smart transportation systems. This study tackles the issue of database manipulation attacks in smart transportation networks by proposing a signature-based intrusion detection system. The introduced More >

  • Open Access

    ARTICLE

    Action Recognition via Shallow CNNs on Intelligently Selected Motion Data

    Jalees Ur Rahman1, Muhammad Hanif1, Usman Haider2,*, Saeed Mian Qaisar3,*, Sarra Ayouni4

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.071251 - 12 January 2026

    Abstract Deep neural networks have achieved excellent classification results on several computer vision benchmarks. This has led to the popularity of machine learning as a service, where trained algorithms are hosted on the cloud and inference can be obtained on real-world data. In most applications, it is important to compress the vision data due to the enormous bandwidth and memory requirements. Video codecs exploit spatial and temporal correlations to achieve high compression ratios, but they are computationally expensive. This work computes the motion fields between consecutive frames to facilitate the efficient classification of videos. However, contrary… More >

  • Open Access

    ARTICLE

    Blockchain and Smart Contracts with Barzilai-Borwein Intelligence for Industrial Cyber-Physical System

    Gowrishankar Jayaraman1, Ashok Kumar Munnangi2, Ramesh Sekaran3, Arunkumar Gopu3, Manikandan Ramachandran4,*

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.071124 - 12 January 2026

    Abstract Industrial Cyber-Physical Systems (ICPSs) play a vital role in modern industries by providing an intellectual foundation for automated operations. With the increasing integration of information-driven processes, ensuring the security of Industrial Control Production Systems (ICPSs) has become a critical challenge. These systems are highly vulnerable to attacks such as denial-of-service (DoS), eclipse, and Sybil attacks, which can significantly disrupt industrial operations. This work proposes an effective protection strategy using an Artificial Intelligence (AI)-enabled Smart Contract (SC) framework combined with the Heterogeneous Barzilai–Borwein Support Vector (HBBSV) method for industrial-based CPS environments. The approach reduces run time… More >

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