Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (174)
  • Open Access

    ARTICLE

    Healing from Human to Human

    Soigner d’humain à humain

    D. Gros

    Psycho-Oncologie, Vol.16, No.2, pp. 260-264, 2022, DOI:10.3166/pson-2022-0192

    Abstract To fulfill its function as well as possible, medical art requires considering each patient in the totality of his biological and biographical being. However, the medical world faces a model fond of standardization of practices and inclined to give primacy to the requirements of science and machines over those of humans. As health professionals, we all strive daily to preserve a harmonious alliance between science and humanity. We aspire to maintain it, but we are aware of the threats hanging over it. This awareness should encourage us to carry out an interdisciplinary reflection. A multidimensional object, infinitely overflowing the biomedical… More >

  • Open Access

    ARTICLE

    Impact of Precariousness and Perceived Social Support, on the Return to Work of Women with Breast Cancer, in the Year Following the Beginning of Adjuvant Treatments

    Influence de la précarité sociale et du soutien social perçu, sur le retour au travail des femmes ayant un cancer du sein, dans l’année suivant le début des traitements adjuvants

    B. Porro, A. Michel, F. Cousson-Gélie

    Psycho-Oncologie, Vol.16, No.2, pp. 273-281, 2022, DOI:10.3166/pson-2022-0181

    Abstract The aim is to assess the associations between social precariousness, perceived social support, and the return to work (RTW) in the first year following the beginning of adjuvant breast cancer treatment. Sixty-eight breast cancer patients encountered when starting their adjuvant treatment (T0) were followed up at 3 (T1) and 12 months (T2). Friends’ informative support at T0 favours the RTW at T1. Precariousness and negative support at T0 and T2 decrease the likelihood of RTW at T2. RTW support should be offered and tailored at the outset of treatment.

    Résumé
    L’objectif est d’étudier les liens entre précarité sociale, soutien… More >

  • Open Access

    REVIEW

    Targeting triple-negative breast cancer: A clinical perspective

    LAZAR S. POPOVIC1,2,*, GORANA MATOVINA-BRKO1, MAJA POPOVIC1,2, KEVIN PUNIE3, ANA CVETANOVIC4,5, MATTEO LAMBERTINI6,7

    Oncology Research, Vol.31, No.3, pp. 221-238, 2023, DOI:10.32604/or.2023.028525

    Abstract Triple-negative breast cancer (TNBC) is a disease with often an aggressive course and a poor prognosis compared to other subtypes of breast cancer. TNBC accounts for approximately 10%–15% of all diagnosed breast cancer cases and represents a high unmet need in the field. Up to just a few years ago, chemotherapy was the only systemic treatment option for this subtype (1). To date, TNBC is considered a heterogeneous disease. One of the existing classifications is based on the analysis of mRNA expression in 587 TNBC cases, in which Lehman et al. proposed six subtypes of TNBC as follows: two basal-like… More > Graphic Abstract

    Targeting triple-negative breast cancer: A clinical perspective

  • Open Access

    ARTICLE

    The role of AFAP1-AS1 in mitotic catastrophe and metastasis of triple-negative breast cancer cells by activating the PLK1 signaling pathway

    SHUIZHONG CEN1,#, XIAOJIE PENG2,#, JIANWEN DENG3,#, HAIYUN JIN4, ZHINAN DENG5, XIAOHUA LIN3, DI ZHU3, MING JIN6, YANWEN ZHU3, PUSHENG ZHANG3, YUNFENG LUO3, HONGYAN HUANG3,*

    Oncology Research, Vol.31, No.3, pp. 375-388, 2023, DOI:10.32604/or.2023.028256

    Abstract Triple-negative breast cancer (TNBC) is characterized by fast growth, high metastasis, high invasion, and a lack of therapeutic targets. Mitosis and metastasis of TNBC cells are two important biological behaviors in TNBC malignant progression. It is well known that the long noncoding RNA AFAP1-AS1 plays a crucial role in various tumors, but whether AFAP1-AS1 is involved in the mitosis of TNBC cells remains unknown. In this study, we investigated the functional mechanism of AFAP1-AS1 in targeting Polo-like Kinase 1 (PLK1) activation and participating in mitosis of TNBC cells. We detected the expression of AFAP1-AS1 in the TNBC patient cohort and… More > Graphic Abstract

    The role of AFAP1-AS1 in mitotic catastrophe and metastasis of triple-negative breast cancer cells by activating the PLK1 signaling pathway

  • Open Access

    ARTICLE

    Senescent mesenchymal stem/stromal cells in pre-metastatic bone marrow of untreated advanced breast cancer patients

    FRANCISCO RAÚL BORZONE1,*, MARÍA BELÉN GIORELLO1, LEANDRO MARCELO MARTINEZ2, MARÍA CECILIA SANMARTIN1,3, LEONARDO FELDMAN4, FEDERICO DIMASE5, EMILIO BATAGELJ6, GUSTAVO YANNARELLI3, NORMA ALEJANDRA CHASSEING1,*

    Oncology Research, Vol.31, No.3, pp. 361-374, 2023, DOI:10.32604/or.2023.028104

    Abstract Breast cancer is the predominant form of carcinoma among women worldwide, with 70% of advanced patients developing bone metastases, with a high mortality rate. In this sense, the bone marrow (BM) mesenchymal stem/stromal cells (MSCs) are critical for BM/bone homeostasis, and failures in their functionality, transform the BM into a pre-metastatic niche (PMN). We previously found that BM-MSCs from advanced breast cancer patients (BCPs, infiltrative ductal carcinoma, stage III-B) have an abnormal profile. This work aims to study some of the metabolic and molecular mechanisms underlying MSCs shift from a normal to an abnormal profile in this group of patients.… More >

  • Open Access

    ARTICLE

    « We-ness, we-disease » : impact sur la résilience sexuelle des couples confrontés au cancer du sein

    “We-ness, We-Disease”: Impact on Sexual Resilience of Couples Facing Breast Cancer

    T. Normandin, A. Stulz

    Psycho-Oncologie, Vol.16, No.3, pp. 295-302, 2022, DOI:10.3166/pson-2022-0210

    Abstract This paper presents our research thesis with the aim of obtaining the interuniversity diploma of sexology.
    Aim: The objective of our research is to observe the link between the sense of “we-ness, we-disease” and the sexual resilience of the couple facing breast cancer.
    Procedure: The methodology was qualitative and observational. Five couples were included in the study and participated in a couple interview. The transcription of research interviews was analyzed using the “We-ness coding scale” (Reid) and a thematic content analysis of intimate and sexual life of the five couples.
    Results: For three couples, the content analysis of the interviews… More >

  • Open Access

    REVIEW

    The progress of combination therapy with immune checkpoint inhibitors in breast cancer

    KAIMIN FAN, JUNWEI WENG*

    BIOCELL, Vol.47, No.6, pp. 1199-1211, 2023, DOI:10.32604/biocell.2023.028516

    Abstract Immunotherapy targets the dysfunctional immune system to induce cancer cell killing by CD8-positive T cells. Immune checkpoint inhibitors (ICIs), specifically anti-PD-1 antibodies, anti-PD-L1 antibodies, and anti-CTLA4 antibodies, have revolutionized the management of many malignancies due to their significant role in generating a durable clinical response. However, clinical data suggest that response rates to ICI monotherapy are low due to the immunologically silent characteristics of breast cancer (BC). Chemotherapy, surgery, radiotherapy, and targeted therapy were recently reported to alter the tumor microenvironment and enhance the ICI response. Some clinical studies supported that ICIs, in combination with other treatment strategies, show superior… More >

  • Open Access

    ARTICLE

    “Cancer Is Not Just about a Disease”: the Experience of Breast Cancer in the Light of Patients’ Metaphors

    « Le cancer, ce n’est pas juste une histoire de maladie » : l’expérience du cancer du sein à la lumière des métaphores des patientes

    A. Guité-Verret, M. Vachon

    Psycho-Oncologie, Vol.17, No.1, pp. 44-50, 2023, DOI:10.3166/pson-2022-0220

    Abstract The aim of this study is to better understand the experience of breast cancer through the analysis of the metaphors in the narratives of women with breast cancer. The blogs of two women were selected and processed according to an interpretative phenomenological analysis. This analysis highlights three metaphors in light of which these women seemed to understand their experience: the body as a medical battlefield, the fragmented body, and the cancer journey. These findings underline the violent changes in the boundaries of the body and the subject that can occur during cancer treatment, as well as the need to integrate… More >

  • Open Access

    ARTICLE

    Associated Factors with Anxiety and Depression Symptoms in Tunisian Women Affected by Breast Cancer

    Facteurs associés à la symptomatologie anxiodépressive chez des femmes tunisiennes atteintes d’un cancer du sein

    M. Karoui, R. Kamoun, H. Nefzi, N. Marrakchi, H. Raies, A. Mezlini, K. Meddeb, F. Ellouze

    Psycho-Oncologie, Vol.17, No.1, pp. 31-37, 2023, DOI:10.3166/pson-2022-0211

    Abstract Aim: The objective of this study is to investigate the prevalence of depression and anxiety in women Tunisian population followed for breast cancer and to identify the socio-demographic, clinical, and of couple relationship factors associated with them.
    Procedure: Cross-sectional study on 100 patients followed for confirmed breast cancer. A questionnaire on the sociodemographic, clinical, therapeutic, conjugal, and sexual characteristics of the couple was completed. The HADS (Hospital Anxiety and Depression Scale) was used for the detection of anxiety and depressive symptoms.
    Results: A clinical score was found in 48% of cases for anxiety and 37% of cases for depression. Patients… More >

  • Open Access

    ARTICLE

    Breast Cancer Diagnosis Using Artificial Intelligence Approaches: A Systematic Literature Review

    Alia Alshehri, Duaa AlSaeed*

    Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 939-970, 2023, DOI:10.32604/iasc.2023.037096

    Abstract One of the most prevalent cancers in women is breast cancer. Early and accurate detection can decrease the mortality rate associated with breast cancer. Governments and health organizations emphasize the significance of early breast cancer screening since it is associated to a greater variety of available treatments and a higher chance of survival. Patients have the best chance of obtaining effective treatment when they are diagnosed early. The detection and diagnosis of breast cancer have involved using various image types and imaging modalities. Breast “infrared thermal” imaging is one of the imaging modalities., a screening instrument used to measure the… More >

Displaying 31-40 on page 4 of 174. Per Page