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  • Open Access

    REVIEW

    A review on re-emerging bacteriophage therapy in the era of XDR

    POOJA BHADORIYA1, RICHA SHARMA1, REKHA MEHROTRA1, SIMRAN KAUR1, ISHA SRIVASTAVA1, MUKUL JAIN2, PRASHANT KAUSHIK3,*

    BIOCELL, Vol.47, No.9, pp. 1915-1930, 2023, DOI:10.32604/biocell.2023.029564

    Abstract In the present medicine world antibiotic resistance is one of the key threats to universal health coverage. Researchers continue to work hard to combat this global health concern. Phage therapy, an age-old practice during the early twentieth century, was outshined by the discovery of antibiotics. With the advent of widespread antibiotic resistance, phage therapy has again redeemed itself as a potential alternative owing to its adeptness to target bacteria precisely. Limited side effects, the ability to migrate to different body organs, a distinct mode of action, and proliferation at the infection site, make phages a profitable candidate to replace conventional… More > Graphic Abstract

    A review on re-emerging bacteriophage therapy in the era of XDR

  • Open Access

    REVIEW

    Efficacy of oral consumption of curcumin/ for symptom improvement in inflammatory bowel disease: A systematic review of animal models and a meta-analysis of randomized clinical trials

    MARLA DE CERQUEIRA ALVES1, MONISE OLIVEIRA SANTOS1, NASSIB BEZERRA BUENO1, ORLANDO ROBERTO PIMENTEL DE ARAÚJO2, MARÍLIA OLIVEIRA FONSECA GOULART2,3,4, FABIANA ANDRÉA MOURA1,5,*

    BIOCELL, Vol.46, No.9, pp. 2015-2047, 2022, DOI:10.32604/biocell.2022.020407

    Abstract

    The roots of the vegetal Curcuma due to its high content of polyphenols, has been used successfully in several clinical situations. This review assessed the effect of curcumin/Curcuma longa on symptoms and metabolic changes in inflammatory bowel disease (IBD). A systematic review of animal models and randomized clinical trials (RCTs) was conducted by searching the following electronic databases: PubMed, CENTRAL, LILACS, Science Direct, and ClinicalTrials.gov. From 997 found records, 62 were included. More than 90% of the animal studies reported an improvement in macroscopic, histologic and/or functional activity; 80% identified decreased oxidative and/or inflammatory biomarkers in animals treated with curcumin.… More >

  • Open Access

    ARTICLE

    A Hybrid Deep Learning Model for COVID-19 Prediction and Current Status of Clinical Trials Worldwide

    Shwet Ketu*, Pramod Kumar Mishra

    CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1896-1919, 2021, DOI:10.32604/cmc.2020.012423

    Abstract Infections or virus-based diseases are a significant threat to human societies and could affect the whole world within a very short time-span. Corona Virus Disease-2019 (COVID-19), also known as novel coronavirus or SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2), is a respiratory based touch contiguous disease. The catastrophic situation resulting from the COVID-19 pandemic posed a serious threat to societies globally. The whole world is making tremendous efforts to combat this life-threatening disease. For taking remedial action and planning preventive measures on time, there is an urgent need for efficient prediction models to confront the COVID-19 outbreak. A deep learning-based ARIMA-LSTM hybrid… More >

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