Noreen Fuentes¹, Janeth Ugang¹, Narcisan Galamiton¹, Suzette Bacus¹, Samantha Shane Evangelista², Fatima Maturan², Lanndon Ocampo^2,3,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-26, 2026, DOI:10.32604/cmc.2025.068104 - 10 November 2025

Abstract This study demonstrates a novel integration of large language models, machine learning, and multi-criteria decision-making to investigate self-moderation in small online communities, a topic under-explored compared to user behavior and platform-driven moderation on social media. The proposed methodological framework (1) utilizes large language models for social media post analysis and categorization, (2) employs k-means clustering for content characterization, and (3) incorporates the TODIM (Tomada de Decisão Interativa Multicritério) method to determine moderation strategies based on expert judgments. In general, the fully integrated framework leverages the strengths of these intelligent systems in a more systematic evaluation… More >

Puneetha B. H.^1,*, Manoj Kumar M. V.^2,*, Prashanth B. S.², Piyush Kumar Pareek³

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-33, 2026, DOI:10.32604/cmc.2025.067706 - 10 November 2025

Abstract Processes supported by process-aware information systems are subject to continuous and often subtle changes due to evolving operational, organizational, or regulatory factors. These changes, referred to as incremental concept drift, gradually alter the behavior or structure of processes, making their detection and localization a challenging task. Traditional process mining techniques frequently assume process stationarity and are limited in their ability to detect such drift, particularly from a control-flow perspective. The objective of this research is to develop an interpretable and robust framework capable of detecting and localizing incremental concept drift in event logs, with a… More >

Zhe Liu^1,2,3,*, Sijia Zhu⁴, Yulong Huang^1,*, Tapan Senapati^5,6,7, Xiangyu Li⁸, Wulfran Fendzi Mbasso⁹, Himanshu Dhumras¹⁰, Mehdi Hosseinzadeh^11,12,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2157-2188, 2025, DOI:10.32604/cmes.2025.072352 - 26 November 2025

Abstract Uncertainty and ambiguity are pervasive in real-world intelligent systems, necessitating advanced mathematical frameworks for effective modeling and analysis. Fermatean fuzzy sets (FFSs), as a recent extension of classical fuzzy theory, provide enhanced flexibility for representing complex uncertainty. In this paper, we propose a unified parametric divergence operator for FFSs, which comprehensively captures the interplay among membership, non-membership, and hesitation degrees. The proposed operator is rigorously analyzed with respect to key mathematical properties, including non-negativity, non-degeneracy, and symmetry. Notably, several well-known divergence operators, such as Jensen-Shannon divergence, Hellinger distance, and χ²-divergence, are shown to be special cases More >

Duong Tien Dung^1,2,3, Ha Hai Nam⁴, Nguyen Long Giang³, Luong Thi Hong Lan^5,*

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5625-5642, 2025, DOI:10.32604/cmc.2025.069636 - 23 October 2025

Abstract Semi-supervised clustering techniques attempt to improve clustering accuracy by utilizing a limited number of labeled data for guidance. This method effectively integrates prior knowledge using pre-labeled data. While semi-supervised fuzzy clustering (SSFC) methods leverage limited labeled data to enhance accuracy, they remain highly susceptible to inappropriate or mislabeled prior knowledge, especially in noisy or overlapping datasets where cluster boundaries are ambiguous. To enhance the effectiveness of clustering algorithms, it is essential to leverage labeled data while ensuring the safety of the previous knowledge. Existing solutions, such as the Trusted Safe Semi-Supervised Fuzzy Clustering Method (TS3FCM),… More >

Duong Tien Dung^1,2,3, Ha Hai Nam⁴, Nguyen Long Giang³, Luong Thi Hong Lan^5,*

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5341-5357, 2025, DOI:10.32604/cmc.2025.068299 - 23 October 2025

Abstract Active semi-supervised fuzzy clustering integrates fuzzy clustering techniques with limited labeled data, guided by active learning, to enhance classification accuracy, particularly in complex and ambiguous datasets. Although several active semi-supervised fuzzy clustering methods have been developed previously, they typically face significant limitations, including high computational complexity, sensitivity to initial cluster centroids, and difficulties in accurately managing boundary clusters where data points often overlap among multiple clusters. This study introduces a novel Active Semi-Supervised Fuzzy Clustering algorithm specifically designed to identify, analyze, and correct misclassified boundary elements. By strategically utilizing labeled data through active learning, our More >

Siliang Chen¹, Dongri Shan^2,*, Yansheng Niu³

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5263-5286, 2025, DOI:10.32604/cmc.2025.067892 - 23 October 2025

Abstract With the increasing deployment of Unmanned Aerial Vehicle-Hangar (UAV-H) clusters in dynamic environments such as disaster response and precision agriculture, existing networking schemes often struggle with adaptability to complex scenarios, while traditional Vertical Handoff (VHO) algorithms fail to fully address the unique challenges of UAV-H systems, including high-speed mobility and limited computational resources. To bridge this gap, this paper proposes a heterogeneous network architecture integrating 5th Generation Mobile Communication Technology (5G) cellular networks and self-organizing mesh networks for UAV-H clusters, accompanied by a novel VHO algorithm. The proposed algorithm leverages Multi-Attribute Decision-Making (MADM) theory combined… More >

Tian Tian^1,2, Boyue Wang^1,2, Xiaxia He^1,2,*, Wentong Wang³, Meng Wang¹

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4885-4898, 2025, DOI:10.32604/cmc.2025.067795 - 23 October 2025

Abstract Attribute-graph clustering aims to divide the graph nodes into distinct clusters in an unsupervised manner, which usually encodes the node attribute feature and the corresponding graph structure into a latent feature space. However, traditional attribute-graph clustering methods often neglect the effect of neighbor information on clustering, leading to suboptimal clustering results as they fail to fully leverage the rich contextual information provided by neighboring nodes, which is crucial for capturing the intrinsic relationships between nodes and improving clustering performance. In this paper, we propose a novel Neighbor Dual-Consistency Constrained Attribute-Graph Clustering that leverages information from… More >

Pasi Fränti^1,*, Claude Cariou², Qinpei Zhao³

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4687-4704, 2025, DOI:10.32604/cmc.2025.066534 - 23 October 2025

Abstract K-means uses the sum-of-squared error as the objective function to minimize within-cluster distances. We show that, as a consequence, it also maximizes between-cluster variances. This means that the two measures do not provide complementary information and that using only one is enough. Based on this property, we propose a new objective function called cluster overlap, which is measured intuitively as the proportion of points shared between the clusters. We adopt the new function within k-means and present an algorithm called overlap k-means. It is an alternative way to design a k-means algorithm. A localized variant is also More >

Xuejun Guo^1,2, Yilin Fu³, Natalia Baran^4,5, Wenxue Ma^6,*

Oncology Research, Vol.33, No.11, pp. 3375-3385, 2025, DOI:10.32604/or.2025.071708 - 22 October 2025

Abstract Cluster of differentiation 47 (CD47), an immune checkpoint commonly referred to as the “don’t eat me” signal, plays a pivotal role in tumor immune evasion by inhibiting phagocytosis through interaction with signal regulatory protein alpha (SIRPα) on macrophages and dendritic cells (DCs). Although early enthusiasm drove broad clinical development, recent discontinuations of major CD47-targeted programs have prompted re-evaluation of its therapeutic potential. The purpose of this commentary is to contextualize the setbacks observed with first-generation CD47 inhibitors and to highlight strategies aimed at overcoming their limitations. Clinical challenges, including anemia, thrombocytopenia, suboptimal pharmacokinetics, and limited… More >

Ana Clara Ciglioni Salustiano^1,2, Gabriela Barbosa^1,3,4, Rodolfo Borges dos Reis^2,4, Amílcar Castro de Mattos^5,6, Athanase Billis⁶, Leonardo O. Reis^1,3,4,*

Oncology Research, Vol.33, No.11, pp. 3417-3428, 2025, DOI:10.32604/or.2025.068023 - 22 October 2025

Abstract Objective: The tumor microenvironment plays a pivotal role in prostate cancer progression and may differ across metastatic sites. This study aimed to evaluate and compare the primary and metastatic prostate adenocarcinoma tumor microenvironment. Methods: A total of 27 formalin-fixed paraffin-embedded tissue samples derived from 17 patients diagnosed with prostate adenocarcinoma, including the primary tumors, and the corresponding metastatic lymphatic and hematogenous lesions from various anatomical sites. Immunohistochemical labeling was performed using antibodies against Cluster of Differentiation 3 epsilon chain (CD3e), CD8 alpha chain (CD8a), Cluster of Differentiation 68 (CD68), Cluster of Differentiation 163 (CD163), Forkhead… More > Graphic Abstract