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  • Open Access

    REVIEW

    Role of Platelet Derivatives and Their Therapeutic Potential in Wound Healing

    Sanggu Kim1, Seongmo Yang1, Soochong Kim1,2,*

    BIOCELL, Vol.49, No.12, pp. 2335-2364, 2025, DOI:10.32604/biocell.2025.072418 - 24 December 2025

    Abstract Regenerative medicine has attracted increasing attention across diverse organs, including the skin, musculoskeletal tissues, eye, and nervous system, where structural repair is limited. Among these, skin wound care is particularly urgent and challenging because diabetic ulcers, pressure injuries, and severe burns often resist standard dressings, debridement, and revascularization, resulting in infection, amputation, and high costs. Platelet-rich plasma (PRP) has gained value because platelets release coordinated growth factors and cytokines (e.g., platelet-derived growth factor, transforming growth factor-β, vascular endothelial growth factor, epidermal growth factor, fibroblast growth factor, and insulin-like growth factor-1) that modulate hemostasis, inflammation, angiogenesis,… More >

  • Open Access

    ARTICLE

    Framework for the Structural Analysis of Fractional Differential Equations via Optimized Model Reduction

    Inga Telksniene1, Tadas Telksnys2, Romas Marcinkevičius3, Zenonas Navickas2, Raimondas Čiegis1, Minvydas Ragulskis2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2131-2156, 2025, DOI:10.32604/cmes.2025.072938 - 26 November 2025

    Abstract Fractional differential equations (FDEs) provide a powerful tool for modeling systems with memory and non-local effects, but understanding their underlying structure remains a significant challenge. While numerous numerical and semi-analytical methods exist to find solutions, new approaches are needed to analyze the intrinsic properties of the FDEs themselves. This paper introduces a novel computational framework for the structural analysis of FDEs involving iterated Caputo derivatives. The methodology is based on a transformation that recasts the original FDE into an equivalent higher-order form, represented as the sum of a closed-form, integer-order component G(y) and a residual… More >

  • Open Access

    ARTICLE

    Predictive and Global Effect of Active Smoker in Asthma Dynamics with Caputo Fractional Derivative

    Muhammad Farman1,2,3,*, Noreen Asghar4, Muhammad Umer Saleem4, Kottakkaran Sooppy Nisar5,6, Kamyar Hosseini1,2,7, Mohamed Hafez8,9

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 721-751, 2025, DOI:10.32604/cmes.2025.069541 - 30 October 2025

    Abstract Smoking is harmful to the lungs and has numerous effects on our bodies. This leads to decreased lung function, which increases the lungs’ susceptibility to asthma triggers. In this paper, we develop a new fractional-order model and investigate the impact of smoking on the progression of asthma by using the Caputo operator to analyze different factors. Using the Banach contraction principle, the existence and uniqueness of solutions are established, and the positivity and boundedness of the model are proved. The model further incorporates different stages of smoking to account for incubation periods and other latent… More >

  • Open Access

    PROCEEDINGS

    Thermoelastic Transient Memory Response Analysis of Spatio-Temporal Non-Localized Porous Hollow Cylinder Based on Moore-Gibson-Thompson Thermoelasticity Theory

    Yixin Zhang, Yongbin Ma*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.012268

    Abstract In this paper, a novel porous thermoelastic model is developed, building upon the existing framework of thermoelastic model. The objective of this study is to investigate the thermoelastic response behavior of porous materials. The Klein-Gordon (KG) operator is employed to describe the effect of spatio-temporal non-localization in the constitutive equation, and the memory-dependent derivative (MDD) is incorporated into the Moore-Gibson-Thompson (MGT) heat conduction equation. The model is applied to study the thermoelastic response of hollow porous cylinders under thermal shock, which accurately captures the complex micro-interaction characteristics and memory-dependent properties of the porous structure. Subsequently,… More >

  • Open Access

    REVIEW

    Extraction, Utilization, Functional Modification, and Application of Cellulose and Its Derivatives

    Wohua He, Fangji Wu, Haoqun Hong*

    Journal of Renewable Materials, Vol.13, No.9, pp. 1707-1763, 2025, DOI:10.32604/jrm.2025.02025-0005 - 22 September 2025

    Abstract Under the background of the current energy crisis and environmental pollution, the development of green and sustainable materials has become particularly urgent. As one of the most abundant natural polymers on earth, cellulose has attracted wide attention due to its green recycling, sustainable development, degradability, and low cost. Therefore, cellulose and its derivatives were used as the starting point for comprehensive analysis. First, the basic structural properties of cellulose were discussed, and then the extraction and utilization methods of cellulose were reviewed, including Sodium Hydroxide based solvent system, N, N-Dimethylacetamide/Lithium Chloride System, N-Methylmorpholine-N-Oxide (NMMO) system, More > Graphic Abstract

    Extraction, Utilization, Functional Modification, and Application of Cellulose and Its Derivatives

  • Open Access

    ARTICLE

    Derivative Free and Dispatch Algorithm-Based Optimization and Power System Assessment of a Biomass-PV-Hydrogen Storage-Grid Hybrid Renewable Microgrid for Agricultural Applications

    Md. Fatin Ishraque1, Akhlaqur Rahman2, Kamil Ahmad1, Sk. A. Shezan3,*, Md. Meheraf Hossain1, Sheikh Rashel Al Ahmed1, Md. Iasir Arafat1, Noor E Nahid Bintu4

    Energy Engineering, Vol.122, No.8, pp. 3347-3375, 2025, DOI:10.32604/ee.2025.067492 - 24 July 2025

    Abstract In this research work, the localized generation from renewable resources and the distribution of energy to agricultural loads, which is a local microgrid concept, have been considered, and its feasibility has been assessed. Two dispatch algorithms, named Cycle Charging and Load Following, are implemented to find the optimal solution (i.e., net cost, operation cost, carbon emission. energy cost, component sizing, etc.) of the hybrid system. The microgrid is also modeled in the DIgSILENT Power Factory platform, and the respective power system responses are then evaluated. The development of dispatch algorithms specifically tailored for agricultural applications… More >

  • Open Access

    ARTICLE

    A Novel Cascaded TID-FOI Controller Tuned with Walrus Optimization Algorithm for Frequency Regulation of Deregulated Power System

    Geetanjali Dei1,2, Deepak Kumar Gupta1, Binod Kumar Sahu2, Amitkumar V. Jha3, Bhargav Appasani3,*, Nicu Bizon4,5,*

    Energy Engineering, Vol.122, No.8, pp. 3399-3431, 2025, DOI:10.32604/ee.2025.067357 - 24 July 2025

    Abstract This paper presents an innovative and effective control strategy tailored for a deregulated, diversified energy system involving multiple interconnected area. Each area integrates a unique mix of power generation technologies: Area 1 combines thermal, hydro, and distributed generation; Area 2 utilizes a blend of thermal units, distributed solar technologies (DST), and hydro power; and Third control area hosts geothermal power station alongside thermal power generation unit and hydropower units. The suggested control system employs a multi-layered approach, featuring a blended methodology utilizing the Tilted Integral Derivative controller (TID) and the Fractional-Order Integral method to enhance… More >

  • Open Access

    ARTICLE

    Synthesis of Cyclohexyl Acrylate Derivative and Its Evaluation as a Plasticizer for PVC

    Zhihong Wang1,#, Wei Wei1,2,#, Song Wang1, Bingli Zhou2, Yingle Chen1, Liu Yang1, Qiaoguang Li2, Lei Zeng1,*

    Journal of Polymer Materials, Vol.42, No.2, pp. 449-462, 2025, DOI:10.32604/jpm.2025.066668 - 14 July 2025

    Abstract In this study, 3,4-Epoxycyclohexylmethyl 3,4-epoxycyclohexanecarboxylate (ECC) and refined Camellia oleifera seed oil (RCOSO) obtained from saponification and acidified hydrolysis has been used as raw materials to perform ring-opening reactions for the preparation of cyclohexyl acrylate derivative (CAR). The structure of the synthesized product was characterized using infrared spectroscopy, Raman spectroscopy, and nuclear magnetic resonance spectroscopy. CAR was employed as a plasticizer to produce modified polyvinyl chloride (PVC) films, dioctyl phthalate plasticizer (DOP) used in reference samples to investigate the influence of different plasticizer molecular structures on the properties of PVC films. Observation suggested that (1) CAR More >

  • Open Access

    ARTICLE

    Analysis of a Laplace Spectral Method for Time-Fractional Advection-Diffusion Equations Incorporating the Atangana-Baleanu Derivative

    Kamran1,*, Farman Ali Shah1, Kallekh Afef 2, J. F. Gómez-Aguilar 3, Salma Aljawi4, Ioan-Lucian Popa5,6,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.3, pp. 3433-3462, 2025, DOI:10.32604/cmes.2025.064815 - 30 June 2025

    Abstract In this article, we develop the Laplace transform (LT) based Chebyshev spectral collocation method (CSCM) to approximate the time fractional advection-diffusion equation, incorporating the Atangana-Baleanu Caputo (ABC) derivative. The advection-diffusion equation, which governs the transport of mass, heat, or energy through combined advection and diffusion processes, is central to modeling physical systems with nonlocal behavior. Our numerical scheme employs the LT to transform the time-dependent time-fractional PDEs into a time-independent PDE in LT domain, eliminating the need for classical time-stepping methods that often suffer from stability constraints. For spatial discretization, we employ the CSCM, where More >

  • Open Access

    ARTICLE

    Investigating the Link between Ascaris Lumbricoides and Asthma in Human with Analysis of Fractal Fractional Caputo-Fabrizio of a Mathematical Model

    Manal Adil Murad1, Shayma Adil Murad2,*, Thabet Abdeljawad3,4,5,6,*, Aziz Khan3, D. K. Almutairi7

    CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.3, pp. 3377-3409, 2025, DOI:10.32604/cmes.2025.064245 - 30 June 2025

    Abstract Asthma is the most common allergic disorder and represents a significant global public health problem. Strong evidence suggests a link between ascariasis and asthma. This study aims primarily to determine the prevalence of Ascaris lumbricoides infection among various risk factors, to assess blood parameters, levels of immunoglobulin E (IgE) and interleukin-4 (IL-4), and to explore the relationship between ascariasis and asthma in affected individuals. The secondary objective is to examine a fractal-fractional mathematical model that describes the four stages of the life cycle of Ascaris infection, specifically within the framework of the Caputo-Fabrizio derivative. A… More >

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